Patents in Class 546/104

Matches 1 - 50 out of 190

1 2 3 4 >

Match	Document	Document Title
1	7511064	Derivatives of 4-(thio- or selenoxanthene-9-ylidene)-piperidine or acridine and its use as a selective 5-HT_2Breceptor antagonist The present invention relates to derivatives of 4-(Thio- or Selenoxanthene-9-ylidene)-piperidine or acridine and pharmaceutically acceptable salts thereof, use of these compounds as a medicament...
2	7351807	Cyanine-sulfenates for dual phototherapy Dye-sulfenate derivatives and their bioconjugates for dual phototherapy of tumors and other lesions. The compounds comprise sulfenates having the formula, t,0080 where E is selected from the group...
3	7300930	Therapeutic acridone and acridine compounds The present invention pertains to acridone and acridine compounds of formula (I), wherein either: (a) K is ═O, L is —H, alpha is a single bond, beta is a double bond, gamma is a single bond...
4	7297555	Hydrophilic chemiluminescent acridinium labeling reagents In accordance with the present invention, it has been discovered that introduction of hydrophilic sulfoalkyl substituents and/or hydrophilic linkers derived from homocysteic acid, cysteic acid,...
5	7122671	Luminescent labelling materials and procedures A compound for use as a chemiluminescent label in immunoassay comprises an aryl acridinium ester linked to an N-succinimidyl moiety. The compound is conveniently linked to a monoclonal antibody or...
6	7041674	Carbamic acid esters with anticholinergic activity A compound of formula 1 wherein X − , A, R 1 , R 2 , R 3 , and R 4 may have the meanings given in the claims and in the specification, processes for preparing them, their use in...
7	RE39047	Luminescence by reacting an acridinium ester with superoxide A light emitting method of an acridinium ester, comprising reacting said acridinium ester and a superoxide anion, and a method of detecting a substance to be examined, comprising detecting a light...
8	6995262	Use of acylsulfonamido-substituted polymethine dyes as fluorescene dyes and/or markers The invention relates to a novel polymethine dyes containing at least one acylsulfonamido group of the formula (I) in which n, Y, A and R have the meaning given in the claims, and at least one...
9	6994980	Chemiluminescent compounds and use thereof A novel chemiluminescent compound is provided. In one embodiment, the novel compound is employed in an assay to detect analytes. The assay to detect analytes includes the steps of binding the novel...
10	6924373	DNA labeling reagents, acridinium-9-carboxamide derivatives and process of preparing DNA labeling compounds The present invention relates to DNA labeling reagents comprising a furocoumarin derivative and a detectable group with or without bound via a binding enhancer, and acridinium-9-carboxamide...
11	6924154	Hydrophilic chemilumescent acridinium labeling reagents In accordance with the present invention, it has been discovered that introduction of hydrophilic sulfoalkyl substituents and/or hydrophilic linkers derived from homocysteic acid, cysteic acid,...
12	6858162	Single molecule realization of the switch and doide combination Diodes and switches are combined in a single molecular species. Thus, the single molecular species is capable of performing more than one function. A single molecular species having both diode and...
13	6800656	Tricyclic compounds and method of treating herpes virus The present invention provides a compound of the formula and pharmaceutically acceptable salts having useful antiviral activity against viruses of the herpes family. Wherein: X=O, (CH 2 ) m , S,...
14	6740649	Cyclic hydroxamic acids as inhibitors of matrix metalloproteinases and/or TNF- α converting enzyme (TACE) The present application describes novel cyclic hydroxamic acids of formula I: or pharmaceutically acceptable salt forms thereof, wherein ring B is a 5-7 membered cyclic system containing from...
15	6664043	Acridinium ester labels having hydrophilic modifiers The present invention is generally directed to detectable chemiluminescent acridinium ester labels having hydrophilic modifiers; to compositions, complexes and/or conjugates which include such...
16	6630481	Viologen linked acridine based molecule and process for the preparation thereof The present invention provides a series of novel bifunctional molecules based on viologen linked acridine, bisacridine and bisacridinium salts of the general formula 1 (1a, 1b, 1c and 1d) and or...
17	6417402	Squaraine based dyes and process for preparation thereof The present invention relates to squaraine dye containing terminal aminoanthracene or acridine groups and to a process for preparation thereof.
18	6417005	Covalently immobilized fluoroionophores as optical ion sensors Fluoroionophores that are functionalised with reactive groups and correspond to the formula I—R 1 —F—R 2 —G, wherein I is a monovalen residue of an ionophore, wherein F is a divalent...
19	6414152	Luminescent labelling material and procedures A compound for use as a chemiluminescent label in immunoassay comprises an aryl acridinium ester linked to an N-succinimidyl moiety. The compound is conveniently linked to a monoclonal antibody or...
20	6413984	8-(heterocyclylmethyl)quinoline derivatives for treating urinary incontinence The invention concerns compounds of formula (I) wherein: A represents either a hydrogen atom or a hydroxyl group; B represents a pyrrolidin-2-yl (D) or 2-piperidyl (E), B capable of being...
21	6410732	Processing and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives Synthetic processes and intermediates are disclosed for the preparation of N-arylacridancarboxylic acid derivatives. The derivatives are esters, thioesters, amides and sulfonimides. A key feature...
22	6355803	Near infrared chemiluminescent acridinium compounds and uses thereof This application relates to long-wavelength acridinium compounds having electron-donating groups, which may either be: (a) Part of an extended conjugation system attached by appropriate functional...
23	6274768	Acridin derivatives This invention relates to intermediates in the preparation of acridin derivatives of general formula ##STR1## or pharmaceutically acceptable salts thereof, and to a method of producing them.
24	6248884	Extended rhodamine compounds useful as fluorescent labels Extended rhodamine compounds exhibiting favorable fluorescence characteristics having the structure ##STR1## are disclosed. In addition, novel intermediates for synthesis of these dyes are...
25	6214816	Heterocyclic compounds The compounds are N-substituted azaheterocyclic compounds of formula I ##STR1## wherein R 1 and R 2 independently are hydrogen, halogen, trifluoromethyl, hydroxy, C 1 -6 -alkyl or C 1 -6 -alkoxy;...
26	6172058	Compounds with pharmaceutical properties A pharmaceutical compound of the formula ##STR1## in which R 1 is C 1 -10 alkyl, C 2 -10 alkenyl, C 2 -10 alkynyl, C 3 -10 cycloalkyl, C 3 -10 cycloalkyl-C 1 -10 alkyl, C 3 -10 cycloalkyl-C 2 -10...
27	6171520	Reagents for labeling SH groups, process for the preparation of them and method for labeling with them Disclosed are SH-labeling reagents containing acridine compounds represented by the following formula (I): ##STR1## wherein A represents the following group: --(CH 2 ) m1 -- or --(CH 2 ) m2...
28	6162918	Xanthene and acridine derivatives The invention relates to new and known tricyclic dione derivatives of the general formula ##STR1## and to their salts which are inhibitors of herpes simplex virus thymidine kinase in the treatment...
29	6162610	Xanthan-ester and acridan substrates for horseradish peroxidase Xanthan esters and acridans are substrates for horseradish peroxidase. These stable, enzymatically cleavable chemiluminescent esters are substrates for horseradish peroxidase which, together with...
30	6130228	Polycyclic compounds Compounds of Formula (I), methods for their preparation, pharmaceutical formulations and use thereof. ##STR1##
31	6126870	Chemiluminescent labeling compounds Chemiluminescent labeling compounds and chemiluminescent labeled conjugates are provided. The compounds comprise an acridan ring bearing an exocyclic double bond and further contain a labeling...
32	6114332	Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumor agents A compound which is a bis(acridinecarboxamide) or bis(phenazinecarboxamide) derivative of formula (I): ##STR1## wherein each X, which may be the same or different in a given molecule, is --CH or...
33	6111109	Process for the preparation of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide A process for producing an acridine carboxamide of formula (I): ##STR1## wherein each of R 1 , R 2 , R 5 and R 6 , which may be the same or different, is H or an organic subsituent, x is from 1 to...
34	6087502	Acridinium compound having a plurality of luminescent groups and binding groups, and conjugate thereof Acridinium compounds and their conjugates exhibiting high chemiluminescence yield are provided. Such compounds may be used to enable a highly sensitive specific binding assay. The acridinium...
35	6071908	Radiation-activated cytotoxin therapy of neoplastic disease A method of treating neoplastic disease wherein a patient in need of such treatment is administered an effective amount of a radiation-activated cytotoxin prodrug (RACP) which has low toxicity,...
36	6037347	Combination preparation for use in dementia The invention relates to a composition which is a pharmaceutical combination preparation comprising a compound which has an acetylcholinesterase-inhibitory action or exhibits muscarinergic action...
37	6020131	Nucleic acid polymer/intercalator monolayer and methods of using and making thereof The present invention has an object to provide an easy method for detecting a nucleic acid polymer in aqueous phase. The present invention provides a method for detecting the amount of nucleic acid...
38	6018047	Acridinium compounds as chemiluminogenic label New acridinium compounds are provided which comply with formula 1, wherein A is a divalent organic moiety, such as an alkylene chain, X is a group which can be transformed together with C-9...
39	6002007	Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays Chemiluminescent acridinium derivatives of the formula I ##STR1## in which R 4 represents a radical of the formula II or III ##STR2## and A θ, X--, R 1 -R 3 , R 5 and R 6 have the stated...
40	5969139	Acridine derivatives The invention relates to new and known tricyclic dione derivatives of the general formula ##STR1## wherein W represents hydrogen or lower alkyl; X represents lower alkyl; Y represents NR1; ...
41	5892042	Acridine derivative metal complexes used for transparent recording medium or optical recording medium An acridine derivative metal complex of formula 2 having a large absorption in the near-infrared range and a reduced absorption in the visible range, which acridine derivative metal complex is used...
42	5891886	Treatment of cancers A new treatment schedule for administration of N- 2-(dimethylamino)ethyl!acridine-4-carboxamide and other related carboxamide anticancer drugs in which the drug is administered in a divided-dose...
43	5883256	Process for removing aromatic heterocyclic compounds product-containing solutions A process for removing aromatic heterocyclic compounds from a product-containing solution, in particular a protein solution, by bringing the solution into contact with a support material. The...
44	5879888	Light emitting method of acridinium derivative and method of detecting substance to be examined using same A light emitting method of an acridinium ester, comprising reacting said acridinium ester and a superoxide anion, and a method of detecting a substance to be examined, comprising detecting a light...
45	5834157	2-acylamino-9-arylacridines, process for their preparation and photosensitive mixtures containing them Compounds of the formula ##STR1## are suitable as photoinitiators in free-radical-polymerizable mixtures and are notable for a reduced tendency to diffusion and sublimation than comparable known...
46	5792863	Acridine derivatives and metal complexes thereof used for transparent recording medium or optical recording medium An acridine derivative metal complex of formula 1 or formula 2 having a large absorption in the near-infrared range and a reduced absorption in the visible range, which acridine derivative metal...
47	5783699	Chemiluminescent acridinium salts Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds...
48	5783696	Special chemiluminescent acridine derivatives Chemiluminescent acridinium derivatives of the formula I ##STR1## in which R 4 represents a radical of the formula II or III ##STR2## and A θ, X--, R 1 -R 3 , R 5 and R 6 have the stated...
49	5669819	Chemiluminescent phenanthridinium Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds...
50	5622964	Heterocyclic derivatives Methods of treating asthma are provided which methods comprise administering to a mammal in need of such treatment an effective amount of a compound of Formula I ##STR1## or a pharmaceutically...

Matches 1 - 50 out of 190

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