Matches 201 - 250 out of 369 < 1 2 3 4 5 6 7 8 >
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4530925 Aminocyclopentane esters and pharmaceutical formulations  
Compounds are described of the formulae (1a) and (1b) ##STR1## in which: --COR 1 is an ester group, n is 1 or 2, W is C 1 -7 alkylene, X is cis or trans --CHCH or --CH 2 CH 2 --, ...
4525588 Chromogenic naphtholactams  
The invention relates to chromogenic naphtholactams of the general formula ##STR1## wherein Q is the radical of a couplable compound, X is oxygen or ##STR2## wherein R is hydrogen, lower alkyl...
4522944 Carboxamido-derivatives of 5H-1,3,4-thiadiazolo[3,2-a]pyrimidines, compositions and use  
The present invention relates to new carboxamido-derivatives of 5H-1,3,4-thiadiazolo[3,2-a]pyrimidines, to a process for their preparation and to pharmaceutical (i.e. anti-inflammatory and...
4518596 Antithrombotic use of 2-(perhydro-1,4-diazino)-pyrimido (5,4,D)-pyrimidines  
Compounds of the formula ##STR1## wherein R 1 is a substituted alkoxy group, or an optionally substituted mercapto or amino group, R 2 is a cyclic imino group, R 3 is hydrogen, phenyl,...
4518597 Substituted benzoxazin-2-ones and pharmaceutical compositions containing them  
This invention is directed to novel benzoxazin-2-ones of the formula ##STR1## wherein A is a sulfur atom or an SO, SO 2 , R--NS, or R--NSO 2 group where R is a hydrogen atom or an acyl...
4514408 N-substituted nicotinamide 1-oxide as histamine H.sub.2 receptor blockers  
N-substituted nicotinamide 1-oxide having histamine H 2 receptor blocking activity of formula ##STR1## wherein X is a nitrogen atom or a CH group and Am represents a mono- or disubstituted amino...
4505910 Amino-pyrimidine derivatives, compositions and use  
Herein is disclosed amino-pyrimidine derivatives, therapeutically acceptable acid addition salts thereof, processes for their preparation, methods of using the derivatives and pharmaceutical...
4500525 Pharmacologically active pyrazolo/4,3-c/pyridines  
The present invention is directed to new pyrazolo/4,3-c/pyridines, the process for their preparation, the pharmaceutical compositions containing them and their use as pharmocologically active...
4499089 2-Alkylthio-1-aminoalkyl-2-pyrroline-3-carbonitriles, compositions and use  
2-Alkylthio-1-aminoalkyl-2-pyrroline-3-carbonitriles and pharmaceutically acceptable acid addition salts, processes for their preparation and formulation into pharmaceutical compositions as well as...
4499091 1-Amino (or substituted amino)-1,4-dihydro-4-oxo-6-fluoro-7-heterylquinoline-3-carboxylic acids and their use as antibacterial agents  
Novel 1-R-1,4-dihydro-4-oxo-6-fluoro-7-(ZN--)-quinolinecarboxyl ic acids and esters thereof, where R is amino, lower-alkylamino, 2-propenylamino or di-lower-alkylamino, R" is hydrogen or...
4497808 N-Oxide compounds useful in the treatment of cardiovascular ailments  
The present invention relates to novel N-oxide compounds that have cardiovascular properties, especially antihypertensive activity, and that correspond to the formula ##STR1## in which Py...
4482549 Aminocyclopentane esters and pharmaceutical formulation  
Compounds are described of the formula ##STR1## in which --COR 1 is a complex ester or thioester group, W is alkylene, X is cis or trans --CHCH or --CH 2 CH 2 --, n is 1 or 2, Y...
4478834 Dihydropyridines and their use in the treatment of asthma  
New dihydropyridines are described. These compounds are useful in the treatment of asthma.
4477449 Certain 1,8-naphthyridine compounds useful as antibacterial agents  
Certain substituted 1,4-dihydro-4-oxo-7-(3-thiazolidinyl or 4-thiomorpholinyl)-1,8-naphthyridine-3-carboxylic acids and derivatives are disclosed as antibacterial agents.
4473568 Antibacterial thiazolidine or thiomorpholine substituted quinolines  
Certain thiazolidine or thiomorpholine substituted quinoline and pyridobenzoxazine compounds are antibacterial agents. Method for their preparation and use are disclosed.
4466965 Phthalazine compounds, compositions and use  
The present invention relates to new compounds of the formula ##STR1## alkylene, or --S-- where R 1 is hydrogen, alkyl, or aryl; W is hydrogen, hydroxy, amino, alkyloxy, aryloxy, O-alkyl, or...
4463001 6-Substituted 6H-dibenzo[b,d]pyran derivatives and process for their preparation  
The present invention relates to new 6-substituted 6H-dibenzo [b,d]pyran derivatives, to a process for their preparation and pharmaceutical and veterinary compositions containing them.
4447428 Prostanoid compounds and pharmaceutical compositions  
Prostanoid compounds are described having the formula: ##STR1## where A is a cyclopentane ring, which is substituted by oxo and/or hydroxy or etherified hydroxy and may be saturated or unsaturated;...
4438112 Prostanoid compounds and pharmaceutical formulations  
Prostanoids are described of the formulae ##STR1## (and the salts thereof) in which: X is cis or trans --CHCH-- or CH 2 CH 2 --; R 1 is C 1 -7 alkyl terminated by --COOR 10 where R 10 is...
4414211 Heterocyclic derivatives of guanidine  
5-Membered, 6-membered and 7-membered heterocyclic derivatives of guanidine having hypoglycemic activity.
4412071 Antiatherosclerotic compositions  
The present invention provides novel antiatherosclerotic furobenzoxazinones, e.g., 4,9-dimethoxy-4H-furo[3,2-g][1,3]benzoxazin-4-ones. These compounds are structurally and pharmacologically related...
4406897 6-Aryl-4-hydrazinyl-s-triazin-2-ones  
4399134 Pyrroloquinoline and benzoquinolizine compounds and antimicrobial compositions  
A benzoheterocyclic compound of the formula (I) ##STR1## wherein R 1 , R 2 , R 3 and n are as defined, and its pharmaceutically acceptable salts, processes for preparing same and antibacterial...
4387225 Heterocyclic alkylene triazinones  
Heterocyclic alkyl s-triazine compounds are prepared from the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give respectively...
4380547 Dihydropyridine compounds which are substituted in the 4-position by imidazolyl or thiazolyl and their medicinal use  
The invention relates to dihydropyridine compounds of formula (I) as defined in the specification, containing a hetero-ring substituent in the 4-position. Also included in the invention are...
4356024 Process for the preparation of 1-amino-1,3,5-triazine-2,4(1H, 3H)-dione compounds  
A process for the preparation of a 1-amino-1,3,5-triazine-2,4(1H, 3H)-dione compounds comprising the steps of reacting an N-substituted imido-dicarboxylic acid diaryl ester with an...
4345083 (1-Methyl-2-quinolinylidene) derivatives of guanidine  
(1-Methyl-2-pyridinylidene) and (1-methyl-2-quinolinylidene) derivatives of guanidine having hypoglycemic activity.
4342756 Aminocyclopentane alkenoic acids and esters and pharmaceutical compositions  
Compounds are described of the formula ##STR1## (and their salts and solvates) in which: X is cis or trans --CHCH--; R 1 is C 1 -7 alkyl terminated by --COOR 3 where R 3 is H, C 1 -6 alkyl...
4335123 1-Acyl-8-(3-amino-2-hydroxypropoxy)-1,2,3,4-tetrahydroquinolines, compositions and use  
A 1-acyl-8-[2,3-epoxypropoxy]- and/or 1-acyl-8-[3-halo-2-hydroxypropoxy]-1,2,3,4-tetrahydroquinoli ne are reacted with primary and secondary amines to obtain corresponding physiologically-active...
4331680 Pesticidal compounds, compositions and methods  
Novel compounds are described which are substituted benzophenone hydrazones. They have pesticidal activity, especially against insects and acarids, and pesticidal compositions and methods are...
4324893 4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives  
4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives are anti-secretory agents for use in the treatment of peptic ulcer disease.
4321373 2-Hydroxy-3-naphthoic acid amides  
This invention relates to 2-hydroxy-3-naphthoic acid amides of the general formula: ##STR1## wherein R 1 is hydrogen, a substituted or unsubstituted alkyl, cycloalkyl, aralkyl, or aryl group, and...
4316013 Substituted heterocyclic methine dyes  
Disclosed are disperse dyes for the dyeing of synthetic fibers such as cellulose acetate, triacetate, polyamide and especially polyester and its blends, which have the general formula ##STR1## in...
4305938 2,8-Disubstituted-10-hydroxy-5,5-dimethyl-tetrahydro-and hexahydro-5H-[1]-benzopyrano[4,3-c]pyridines, compositions and use  
The present invention provides 2,8-disubstituted-10-hydroxy-5,5-dimethyl-tetrahydro-and hexahydro-5H-[1]-benzopyrano[4,3-c]pyridines represented by Formulae I-III: ##STR1## wherein: R is selected...
4297498 4-Tertiary-amino-2,6-diaminopyridine 1-oxides  
A series of 2,6-diamino-4-tertiary-amino-pyridine 1-oxides is disclosed. Substituents in the 4-position include diethylamino, pyrrolidinyl, piperidino, morpholino, thiomorpholino, and...
4289765 4-Aminopyridines and medicaments containing the same  
4-Aminopyridines of the formula ##STR1## in which R 1 is hydrogen or alkyl of up to 6 carbon atoms and R 2 represents (a) alkyl of up to 6 carbon atoms substituted up to three times with at...
4288437 2-[(Amino)-aryl-methylene]-benzo[b]thiophen-3(2H)-ones  
Compounds of the formula ##STR1## wherein Ar is phenyl; mono- or di-substituted phenyl, where the substituents are one to two halogens, one to two alkyls of 1 to 3 carbon atoms, or one amino,...
4287338 Sulfooxy-pyrimidinium, -pyridinium, and -triazinium hydroxide inner salts  
The present invention provides novel substituted sulfooxy-pyrimidinium, -pyridinium, and -triazinium hydroxide inner salts. These compounds are useful for the treatment of hypertension and...
4284632 3-Pyrrolin-2-one derivatives and compositions  
New 3-cyclicaminoalkoxy-4-phenyl-3-pyrrolin-2-ones are disclosed. These compounds exhibit anti-hypertensive and vasodilatory action.
4284629 Process for the preparation of 4-pyridone-3-carboxylic acids and/or derivatives thereof  
The invention provides 4-pyridone-3-carboxylic acids and derivatives thereof together with a method for their preparation. Also included in the invention are compositions containing said...
4281120 7H-1,3,4-Thiadiazolo-[3,2-a]-pyrimidin-7-one-5-carboxylic compounds  
Derivatives of 7H-1,3,4-thiadiazolo-[3,2-a]-pyrimidin-7-one-5-carboxylic acid having basic substituents in the 2-position, the alkyl esters and/or pharmaceutically useable salts of these compounds...
4266062 (1-Methyl-2-pyridinylidene) derivatives of guanidine  
(1-Methyl-2-pyridinylidene) and (1-methyl-2-quinolinylidene) derivatives of guanidine having hypoglycemic activity.
4254116 5H-[1]Benzopyrano[3,4-d]pyridines  
5H-[1]Benzopyrano[3,4-d]pyridines represented by the formula ##STR1## wherein each R 1 is loweralkyl, R 2 is alkyl, cycloalkyl or ##STR2## wherein Y is a straight or branched chain alkylene group...
4250173 Heterocyclic compounds and pharmaceutical use  
A compound, with hypolgycaemic activity, having formula (II) or a pharmaceutically acceptable quaternary ammonium or acid addition salt thereof: ##STR1## wherein X represents oxygen or sulphur; n 7...
4247551 N-Pyrrolyl-pyridazineamines and their use as antihypertensive agents  
New-pyrrolyl-3-pyridazineamines having a further aminic substituent in the position 6. The compounds are useful as antihypertensive agents and may be prepared from 6-amino substituted-3-hydrazino...
4246406 Heterocyclic substituted pyrazinoylguanidines  
The case involves novel heterocyclic substituted pyrazinoylguanidines and a process for preparing same. The heterocyclic pyrazinoylguanidines are eukalemic agents possessing diuretic and...
4242347 Hypotensive indolylalkylpiperidyl guanidines and isoureas  
1-(Indolyl-3-alkyl)-3 or 4-(ureido or guanidino)-piperidines, e.g. those of the formula ##STR1## R=H; alkyl; free, etherified or esterified OH or SH; CF 3 , NO 2 or NH 2 m=1-4; n=2 or 3; ...
4235996 Bis(2-imida zolin-2-ylhydrazone)-9,10-dihydro-9,10-anthracenedicarboxaldehydes  
This disclosure describes 9,10-dihydroanthracene-9,10-dicarboxaldehyde-bis-hydrazones and derivatives thereof useful as antibacterial agents, for inhibiting the growth of transplanted mouse tumors,...
4232017 Treatment of psychic disorders and inflammation with fused isoquinolines  
New tricyclic ortho-fused heterocyclic compounds of formula ##STR1## wherein A is the group ##STR2## or the group ##STR3## in which R represents hydrogen, (C 1 -4)alkyl, phenyl or tolyl and R 1 ...
4228281 Dicarboxylic acids containing triazine rings  
Dicarboxylic acids containing at least two triazine rings are very suitable for producing thermoplastic polyesters having high glass transition temperatures and high dimensional stability under...
Matches 201 - 250 out of 369 < 1 2 3 4 5 6 7 8 >