Patents in Class 544/49

Matches 1 - 50 out of 150

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Match	Document	Document Title
1	7598240	Benzothiazin-3-one compound and intermediate therefor A medicine which contains as an active ingredient a benzothiazin-3-one-compound represented by the formula (1): (wherein n is 3 or 4; R represents ethyl or hydrogen; and R 1 represents...
2	7595343	Inhibitors of histone deacetylase The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides...
3	7566707	Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions The present invention relates to substituted imidazo-pyridinones and imidazo-pyridazinones of general formula wherein Y and R 1 to R 4 are defined as in claim 1 , the tautomers, enantiomers,...
4	7482337	Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions Disclosed are substituted xanthines of general formula wherein R 1 to R 4 are defined hereinbelow, the tautomers, the stereoisomers, the mixtures thereof, the prodrugs thereof and the salts...
5	7419542	2,9-dichloro-quinacridone as α-quinacridone crystal phase inhibitor The invention is directed to a method or use of 2,9-dichloro-quinacridone as an alpha crystal phase inhibitor and optionally, 4,11-dichloroquinacridone during the beta-quinacridone or...
6	7407950	N-(heteroaryl)-1H-indole-2-carboxamide derivatives and their use as vanilloid TRPV1 receptor ligands The invention concerns compounds of general formula (I), wherein n, X 1 , X 2 , X 3 , X 4 , Z 1 , Z 2 , Z 3 , Z 4 , Z 5 and W are as defined herein. Said compounds are ligands of the TRPV 1 ...
7	7232826	Tyrosine kinase inhibitors The present invention provides compounds of Formula I or II that are useful as anti-cancer agents and other diseases that can be treated by inhibiting tyrosine kinase enzymes
8	7199118	Benzothiazine derivatives, their preparation and use This invention relates to novel benzothiazine derivatives of Formula I useful as modulators of the AMPA sensitive glutamate receptors, pharmaceutical compositions comprising such compounds and...
9	7101428	2,9-Dichloro-quinacridone as alpha-quinacridone crystal phase inhibitor The invention is directed to a method or use of 2,9-dichloro-quinacridone as a crystal phase inhibitor during the beta-quinacridone or gamma-quinacridone crude pigment particle size reduction...
10	6967248	Crystalline forms of meloxicam and processes for their preparation and interconversion The invention relates to the new crystalline forms II, III and V of meloxicam; to the processes for obtaining the crystalline forms I, II, III and V; and, finally, to the interconversion processes...
11	6894041	Oxazolyl-acid amide derivatives useful as inhibitors of PDE4 isozymes This application is directed to compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic...
12	6881840	Benzothiazine dyes for imaging elements This relates to a dye represented by Formulae II and IIA below: wherein; R 1 represents a hydrogen, an aryl group containing 6 to 14 carbon atoms, or an alkyl group containing 1 to 12...
13	6869948	Meloxicam for oral administration The invention relates in its first aspect to a rapidly decomposing tablet for pain therapy containing meloxicam...
14	6869945	Pyrrolyl-and imidazolyl-acid amide derivatives useful as inhibitors of PDE4 isozymes This application is directed to compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic...
15	6844338	Piperidyindoles as serotonin receptor ligands A pharmaceutical compound of the formula (I) in which R 1 and R 2 are each hydrogen or C 1-6 alkyl, R 3 is —SR 10 , —SOR 10 , —SO 2 R 10 , —COR 10 , —CH 2 OH or —CONHR 11 , where R...
16	6713477	Hydroxamic acid derivatives A hydroxamic acid derivative represented by formula (1) or a prodrug thereof, or a pharmaceutically acceptable salt thereof, which has a matrix metalo-proteinase inhibitor.
17	6683101	Bicyclic cyclohexylamines and their use as NMDA receptor antagonists Described are heterocycle-substituted cyclohexylamines of formula (I), and their pharmaceutically acceptable salts thereof. The compounds of the formula (I) are antagonists of NMDA receptor channel...
18	6664251	Benzothiazine derivative Disclosed are benzothiazine derivatives represented by the following formula (I): wherein the dashed line indicates the presence or absence of a bond; Z represents one of the following groups: ...
19	6642383	Oxopiperazinyl derivatives and light stabilized compositions Compounds of the formula (I) wherein p is zero or 1; q and r, independently of each other, are an integer from 1 to 6; and s is a number ranging from 1 to 8; X is —O— or, when p is 1, X is...
20	6559144	Bicyclic amino acids Compounds of the formula I in which X, Y, Z, R 1 , R 2 , R 3 , R 4 , R 5 , R 7 , R 8 , R 11 , m and n have the meanings stated in claim 1, and their physiologically acceptable salts can be...
21	6545150	Certain benzothiazine dioxide endothelin antagonists and processes for their preparation The instant invention is a series of benzothiazine dioxides, or a pharmaceutically acceptable salt thereof, which are potent endothelin A antagonists with profound in vitro activity, and improved...
22	6448241	Thiazolobenzoheterocycles, their preparation and medicaments containing them Compounds of formula (I): their racemates, enantiomers, diastereoisomers and inorganic acid salts and organic acid salts thereof, processes for preparing them and the medicaments containing them...
23	6440962	Certain benzothiazine dioxide endothelin antagonists and processes for their preparation The instant invention is a series of benzothiazine dioxides, or a pharmaceutically acceptable salt thereof, which are potent endothelin A antagonists with profound in vitro activity, and improved...
24	6436927	IL-8 receptor antagonists The present invention involves certain 8-ureido and 8-thioureido, 1,2-benzothiazines, 1,2,4-benzothioxazines and 1,2,4-benzothiodiazines useful in the treatment of disease states mediated by the...
25	6329366	Pharmaceutical compounds A pharmaceutical compound of the formula ##STR1## in which R 1 and R 2 are each hydrogen, halo, cyano or methyl, the dotted line represents an optional double bond, ##STR2## where R 4 and R 5...
26	6316413	Peptide agonists of bradykinin B2 receptor The invention concerns a pseudopeptide compounds selected among the set constituted by: (i) the compounds of formula (I): ##STR1## in which: A 1 represents a single bond, D-Arg or L-Lys; ...
27	6069114	2-amino-4-bicycloamino-1,3,5-Triazines, their preparation, and their use as herbicide and plant growth regulators Compounds of the formula (I) and their salts ##STR1## in which R 1 to R 6 , Y 1 , to Y 2 , Y 3 , m and n are as defined in claim 1 are suitable as herbicides and plant growth regulators. They can...
28	5856503	Aminoalkyl-substituted benzo-heterocyclic compounds Aminoalkyl-substituted benzo-heterocyclic compounds of the formula ##STR1## wherein M, Q, R and T are as defined in the specification, as well as acid addition salts thereof. These compounds are...
29	5773437	Alkylenediamine derivatives The present invention relates to alkylenediamine derivatives which relieve urinating contraction and therefore are of value as active ingredients of therapeutic agents for treating dysuria.
30	5719151	Substituted benzene compounds Phthalazinedione compounds and pharmaceutical compositions are described. The compositions are useful in treating human or animal patients to alleviate or cure disease or disease symptoms caused by...
31	5610318	Imidocarboxylic acid activators and sulfimidocarboxylic acid activators processes for their preparation and their use This invention is directed to a process for preparing a compound containing a persalt activators and salts thereof which are derived from imidocarboxylic acids and sulfimidocarboxylic acids of the...
32	5602236	Metal-containing steroid mimics and ligands useful in the preparation thereof Metal-containing steroid mimic complexes are provided. Compositions containing a metal ion incorporated into a steroid skeleton structure and ligands useful in the preparation of such compositions...
33	5599811	Benzothiazine dioxides as endothelin antagonists Novel benzothiazine dioxides which are antagonists of endothelin are described, as well as novel intermediates used in their preparation, methods for the preparation, and pharmaceutical...
34	5563144	Antiserotonins, their preparation and pharmaceutical compositions containing them This invention relates to compounds having the formula R 1 -(CH 2 ) n -Het wherein R 1 is a residue having the formula (B), (C), (D); Het represents a radical phenyl-4 tetrahydro-1,2,3,6...
35	5547953	Substituted 1-oxo-1,2-dihydroisoquinolinoylguanidines and 1,1-dioxo-2H-1,2-benzothiazinoylguanidines, a process for their preparation, their use as medicaments or diagnostic agents, and medicaments containing them Substituted 1-oxo-1,2-dihydroisoquinolinoylguanidines and 1,1-dioxo-2H-1,2-benzothiazinoylguanidines, a process for their preparation, their use as medicament or diagnostic agent, and also a...
36	5504095	Aminobenzosultam derivatives as lipoxygenase inhibitors Aminobenzosultam derivatives, which are inhibitors of lipoxygenase, having the formula ##STR1## and the pharmaceutically acceptable acid addition salts thereof, wherein Ar is cycloalkyl having five...
37	5468857	Fungicides Fungicidal compounds of the formula (I): ##STR1## and stereoisomers thereof, wherein K is oxygen or sulphur; Z is optionally substituted aryl or optionally substituted heteroaryl; X is a specified...
38	5321025	Benzothiaziny derivatives The invention concerns a bicyclic heterocyclic compound of the formula I ##STR1## wherein Q is an optionally substituted 10-membered bicyclic heterocyclic moiety containing 1 or 2 N's and a further...
39	5187276	2-pyrimidinyl-1-piperazine derivatives The invention relates to substituted 2-pyrimidinyl-1-piperazine derivatives defined herein by formula (I), processes for their manufacture, compositions containing said substituted...
40	5149703	Quinoline-substituted chromans and related compounds as leukotriene antagonists Compounds having the formula I: ##STR1## are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents....
41	5132304	Benzothiazine derivatives and their applications as medicinal products or as synthesis intermediates for medicinal products The invention relates to the compounds corresponding to the general formula I ##STR1## in which: R 1 represents a lower alkyl radical (having one to four carbon atoms), a phenyl radical or a...
42	5097027	Heterocyclic compounds Heterocyclic compounds of the formula ##STR1## are used as pigments for surface coatings and for coloring and pigmenting high molecular weight organic material.
43	5081118	Benzothiazine dioxide derivatives A series of novel oxyethyl derivatives of certain selected enolic oxicam compounds are disclosed, including certain novel oxyethyl derivatives of...
44	5004742	Benzothiazine-1,1-dioxide derivatives The present invention relates to novel benzothiazine-1,1-dioxide derivatives. These benzothiazine-1,1-dioxide derivatives have a high hyaluronidase-inhibiting activity and accordingly can be used...
45	5003074	N-fluorinated sulfonamides Compounds of formula I ##STR1## wherein R 1 , R 2 , R 3 and R 4 are H, alkyl or aryl, m and n are 0 or 1, and A is a divalent organic radical which, with (CR 1 R 2 ) m NF--SO 2 (CR 3 R 4 ) n ...
46	4952580	Pesticidal polyhaloalkene derivatives Polyhaloalkene compounds of the formula: ##STR1## wherein X is sulfur, oxygen, or nitrogen, Y 1 and Y 2 are fluorine, Z is hydrogen or the same as Y 1 and Y 2 , and n is 1-4; provided that: ...
47	4948416	Phenyl-substituted sulfonamides This invention relates to novel condensed ring sulfonylureas and their use as herbicides and growth regulants.
48	4939140	Heterocyclic oxophthalazinyl acetic acids A heterocyclic oxophthalazinyl acetic acid having aldose reductast inhibitory activity of the formula ##STR1## wherein X is oxygen or sulfur; Z is a covalent bond, O, S, NH or CH 2 or CHR 5 Z is...
49	4919705	Trifluoromethanesulfonamide derivative, a method for the preparation thereof and a herbicide containing the same The present invention relates to a trifluoromethanesulfonamide derivative represented by the general formula given below, a herbicide with the derivative as the active ingredient and a method for...
50	4908056	Heterocyclic acyl sulfonamides This invention relates to novel heterocyclic carbonyl sulfonamides which are particularly useful as agricultural chemicals.

Matches 1 - 50 out of 150

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