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3980655 |
Basically substituted 1,4-dihydro-2H-isoquinoline derivatives and process for preparing them
1,4-Dihydro-2H-isoquinoline derivatives of the general formula I ##SPC1## in which R 1 represents hydrogen or straight chain or branched alkyl of 1 to 6 carbon atoms, R 2 represents low...
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3957791 |
Hydroxyalkyl-piperazino-quinoline nitrates
Disclosed are compounds of the class of quinolines substituted at the 2-, 3- or 4- position by an amino function bearing a hydroxyalkyl nitrate moiety, e.g. 4-(2-hydroxyethylpiperazino)-quinoline...
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3948898 |
1,3-Dioxo-2-aminoalkyl-4,4-dimethyl-isoquinolines and salts thereof
Compounds of the formula ##SPC1## Wherein R 1 is hydrogen, halogen, methoxy or methylthio R 2 is hydrogen or methoxy, n is 2 or 3, and A is ##SPC2## Or ##SPC3## Where R 3 is...
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3948917 |
1,4-Dithiino(2,3-c)pyrrole derivatives
New compounds of the formula: ##SPC1## Wherein A is a phenyl, pyridyl, pyridazinyl, 2-, 3- or 4-quinolyl or naphthyridinyl radical, or a said radical substituted by one or two atoms or radicals...
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3944551 |
N-Coumaranyl and chromanyl -methyl-or sulfur analogs thereof-N'- thiazolyl piperazines
Disubstituted piperazines of the formula: ##SPC1## Wherein: n is 1 or 2; X is oxygen or sulfur; R is hydrogen or lower alkyl; Het is pyridyl, pyrimidinyl, pyridazinyl, pyrazinyl,...
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3932412 |
1-(4-Hydroxyalkylpiperazino)-isoquinoline nitrates
Disclosed are compounds of the class of isoquinolines substituted at the 1-position by an amino function bearing a hydroxy-alkyl nitrate moiety, e.g.,...
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3932416 |
N-tetrazolyl quinaldamides
Compounds of the general formula (I): ##SPC1## in which R 1 , R 2 and R 3 may be the same or different and each represents a hdyrogen atom, an alkyl group, a nitro group, a halogen atom or a...
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3929791 |
2 Substituted-10[4-(2-oxazolidi none-lower alkyl)]-piperazine-dibenzo[b,f]t
Dibenzothiepin derivatives of the general formula ##SPC1## Wherein m, n, R 1 , R 2 , R 3 and X are as hereinafter set forth, And salts thereof as well as processes for their manufacture are...
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3917593 |
N-alkenyl and N-alkynyl (2-quinolyl)thio-acetamides
The compounds are N-alkenyl and N-alkynyl thioamides, for example N-allyl and N-propargyl 2-(2-pyridyl)thioacetamide, which are inhibitors of gastric acid secretion.
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3915965 |
2-Alkoxy(and 2-amino)-3-amino-2-heterocyclic-thiopropanamides
The compounds are 2-alkoxy(and 2-amino)-3-amino-2-heterocyclic-thiopropanamides, for example 2-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)thiopropanamide
, which are inhibitors of gastric acid...
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3914231 |
(-)(Cis-1,2-epoxypropyl)-phosphonic acid and salts thereof
(-) (Cis-1,2-epoxypropyl)-phosphonic acid, a water soluble acidic substance, and its salts are active against both gram-positive and gram-negative bacteria. The antibiotic is produced by growing...
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3910915 |
1-Aryl-2-[(substituted amino)alkanoyl]-1,2,3,4-tetrahydroisoquinolines
1-Aryl-2-[(substituted amino)alkanoyl]-1,2,3,4-tetrahydroisoquinolines having anti-arrhythmic, anti-bacterial, anti-fungal, anti-algal, anti-protozoal and anthelmintic activity are described...
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3905982 |
1-Aryl-n-dialkylaminoalkyl-3,4-dihydro-2(1H)-isoquinolinecarboxamides and related compounds
1-Aryl-N-dialkylaminoalkyl-3,4-dihydro-2(1H)-isoquinolinecar
boxamides and related N-substituted amides having anti-arrhythmic, anti-bacterial, anti-fungal, anti-algal and anthelmintic activity are...
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3886163 |
1,3(2H,4H)-dioxoisoquinoline-4-carboxamides
1,3(2H,4H)-Dioxoisoquinoline-4-carboxamides, nuclear unsubstituted and substituted, are prepared by reacting the appropriate homophthalimide with potassium cyanate. Secondary carboxamides are...
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3884921 |
Isoindoline derivatives
Isoindolin-1-one derivatives substituted in the 2-position by an unsubstituted or substituted quinolyl radical, substituted in the 3-position by a 4-methylpiperazin-1-ylcarbonyloxy or...
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3876645 |
Pyridine thioacetamide derivatives
Compounds of the formula ##SPC1## Wherein R 1 is hydrogen, lower alkyl, lower alkoxy or halogen and n is an integer of 1 to 4, or wherein (R 1 ) n is a divalent straight chain hydrocarbon radical...
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3860592 |
2-ALKOXY-3-AMINO-2-HETEROCYCLIC-THIOPROPANAMIDES
The compounds are 2-alkoxy(and 2-amino)-3-amino-2-heterocyclic-thiopropanamides, for example 2-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)thiopropanamide
, which are inhibitors of gastric acid...
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3856796 |
HYDROXYALKYL-SUBSTITUTED-AMINO-QUINOLINES AND NITRATES THEREOF
Disclosed are compounds of the class of quinolines substituted at the 2-, 3- or 4- position by an amino function bearing a hydroxyalkyl nitrate moiety, e.g. 4-(2-hydroxyethylpiperazino)-quinoline...
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3759924 |
1-AMINO-3(OR4)-PHENYL-3,4-DEHYDROISOQUINOLINES
3,4-Dihydroisoquinoline derivatives of the formula:- ##SPC1## Wherein the symbols R represent hydrogen, halogen or methoxy, or together form the methylenedioxy radical, the symbols R 1 and R 2 ...
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3723434 |
PIPERAZINO ISOQUINOLINE BRONCHODILATORS
A series of novel 4-piperazino-6,7-dialkoxyquinazolines and 1-piperazino-6,7-dialkoxyisoquinolines have been prepared, including their acid addition salts. These compounds are useful in therapy as...
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3692790 |
5-(AMINOALKYLAMINO)-6(OR)-HALO-8-QUINOLINEMETHANOLS, THEIR ALKYL ETHERS AND ALKANOYL ESTERS
5-(Aminoalkylamino)-6(or 7)-halo-8-quinolinemethanols, their lower-alkyl ethers and lower-alkanoyl esters, having schistosomacidal activity, are prepared by reducing the corresponding lower-alkyl...
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3682920 |
(PHENYL PIPERAZYL ALKYL) 3,4-DIHYDROCARBOSTYRIL
1-Substituted derivatives of 3,4-dihydrocarbostyril that are useful as analgesic agents. These compounds are prepared by reacting a 3,4-dihydrocarbostyril or substituted 3,4-dihydrocarbostyril with...
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3682927 |
5,7-BICHLORO-8-HYDROXY-2-ACETYLAMINO QUINOLINE
An extensive series of quinoline derivatives is disclosed, more particularly several 5,7-bichloro-8-hydroxy-quinolines carrying various substituents in the 2-position. The most interesting...
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3671518 |
BENZODIAZEPIN-2-ONES AND PROCESSES FOR THEIR PREPARATION
3-substituted benzodiazepin-2-ones, derivatives thereof and processes for their preparation are described. These compounds are useful as anti-convulsants, muscle relaxants and sedatives.
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3668207 |
2-AMINO-4-ARYL-QUINOLINES
2-Amino-4-aryl-quinolines, e.g. those of the formula ##SPC1## Acyl derivatives, quaternaries and salts thereof, exhibit antiinflammatory effects.
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3625969 |
6-SULFAMYL-4-HYDROXY-3-CARBOXY-QUINOLINES
Compounds of the formula ##SPC1## In which R = disubstituted amino group R 3 = lower aliphatic hydrocarbon radical, lower alkoxy group, lower alkenyloxy group, hydroxy group, halogen,...
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3622457 |
PROCESS FOR PREPARING 5-(AMINOALKYLAMINO)-6 (OR 7)-HALO-8-QUINOLINE METHANOLS
5-(aminoalkylamino)-6(or 7)-halo-8-quinolinemethanols, having schistosomacidal activity, are prepared by subjecting the correspoonding 6(or 7)-halo-5-(aminoalkylamino)-8-methylquinoline to the...
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3551413 |
BENZO-LACTAMS
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3542785 |
2-HYDROXY-4-ARYL-QUINOLINES
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3538101 |
4 PHENOL DIHYDROQUINOLINES
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3517005 |
CERTAIN 2- AND 4-SUBSTITUTED QUINAZOLINES
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3493570 |
QUINOLINE DERIVATIVES
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3488728 |
N-(NITRO-FURFURYLIDENE-METHYL-HETEROCYCLYL)-AMIDINES
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3472857 |
N-(3-PYRAZOLYL-PROPYL)-N'-PHENYL PIPERAZINES
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3444173 |
SUBSTITUTED 8-HYDROXY-QUINOLINE DERIVATIVES
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3399199 |
Nitroalkyl-piperazines
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3393195 |
1, 2, 3, 6, 7, 11b-hexahydro-4h-pyrazino-2, 1-a-isoquinolines
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3387001 |
Novel aminoacyl esters of desacetyl vincaleukoblastine
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3374231 |
Hydrazones of 1-amino-4-(xanthenyl and thioxanthenyl)piperazines
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3367936 |
4-(PIPERAZINOALKYL)-PYRAZOLES
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3362956 |
1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines
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3351525 |
Coccidiostatic compositions and methods of using same
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3341519 |
Novel benzoxazines, benzothiazines, benzoxazepins and benzothiazepins
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3331843 |
1-substituted-4-substituted aminoalkylene piperazines
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3330823 |
N-amino-loweralkylene-benzo-lactams
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3324129 |
Quinoline derivatives
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3311632 |
3-acetyl-cinchoninic acid compounds
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3275628 |
4-substituted-aliphatic-2, 2-dialiphatic-1, 2-dihydroquinolines
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3272807 |
Unsymmetrical disubstituted aminoalkyl hydrazines
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3272824 |
4-amino-6, 7-di(lower) alkoxyquinolines
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