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5366657 |
Geminal dimethylalkyl compounds, process for their preparation and their use in liquid-crystalline mixtures
Geminal dimethylalkyl compounds, process for their preparation and their use in liquid-crystalline mixtures Geminal dimethylalkyl compounds of the formula (I) ##STR1## in which: R 1 is, for...
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5366659 |
Ferroelectric liquid crystals containing pyrimidine and chiral compounds and liquid crystal compositions containing the same
A liquid crystal composition containing an optically active or a ferroelectric liquid crystal compound represented by the following formula: ##STR1## wherein A can be either --CH 2 -- or --CO--; R...
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5356559 |
Optically active piperazinyl derivatives as liquid crystals
Optically active compounds of the formula ##STR1## wherein rings A 1 and A 2 each independently signify pyridine-2,5-diyl, pyrimidine-2,5-diyl or 1,4-phenylene, which is unsubstituted or...
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5356898 |
Substituted 4,6-di-tertiary-butyl 5-hydroxy-pyrimidines
The present invention is novel compounds which are 4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidine substituted 1,2,4- and 1,3,4-thiadiazoles and oxadiazoles, and 1,2,4-triazoles, and...
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5350750 |
β-carboline-3-hydroxyalkylcarboxylic acid ester derivatives, process for their production and their use in pharmaceutical agents
β-carboline-3-hydroxyalkylcarboxylic acid ester derivatives of formula I ##STR1## in which R A , n, R 4 and R 3 , have the meaning indicated in the claims, as well as their production and their...
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5350851 |
Intermediates and a process for synthesis of tetrahydropteridine C6-stereoisomers, including (6S)-tetrahydrofolate and N5-formyl-(6S)-tetrahydrofolate
Intermediates and a process for the synthesis of 6-monosubstituted tetrahydropteridine C6-stereoisomers, including (6S)-tetrahydrofolic acid. The intermediates are shown in their two enantiomeric...
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5346902 |
Fungicidal diazinyl dioxime
Fungicidal compounds of the formula (I): ##STR1## and stereoisomers thereof, wherein Y is a specified small group or single atom and R 1 and R 2 are selected from a wide range of specified...
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RE34726 |
Ferroelectric liquid crystal compositions containing chiral haloalkoxy tail units
The subject application discloses a chiral nonracemic composition of the general formula: R 1 --Ar--O--CH 2 --C*HX--C*HY--CH 2 --O--R 2 wherein R 1 is an achiral tail of two to sixteen...
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5346647 |
Cyclohexane compounds used in liquid crystalline mixtures
Compounds of the formula ##STR1## wherein n stands for the number 0 or 1; R 1 denotes a group R 3 or R 3 --A 3 --Z 2 -- and R 2 denotes a group R 4 or R 4 --A 4 --Z 3 --; ring A 1 is...
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5344585 |
Use of 4-fluoropyrimidine derivatives as component for ferroelectric liquid crystal mixtures
The use of a fluoropyrimidine derivative of the general formula (I) as component in a ferroelectric liquid crystal mixture comprising 2 to 20 components, ##STR1## in which the symbols have the...
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5342837 |
Fungicides dizinyl oxime ethers
Fungicidal compounds having the formula (I): ##STR1## and stereoisomers thereof, wherein A is hydrogen, halo, hydroxy, C 1 -4 alkyl, C 1 -4 alkoxy, C 1 -4 haloalkyl, C 1 -4 haloalkoxy, C 1 -4...
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5340815 |
2-substituted-4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
The present invention is novel compounds which are 2-substituted-4,6-di-tertiarybutyl-5-hydroxy-1,3-pyrimidines
and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical...
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5340497 |
Fluorophenylpyrimidines
The invention relates to fluorophenylpyrimidines of the formula I: ##STR1## where R 1 , R 2 , A 1 ,A 2 , Q 1 , Q 2 and n have the meaning specified in patent claim 1, and to their use as...
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5338483 |
Anisotropic compounds having nematic phase and liquid crystal mixtures
Liquid crystal mixtures comprise one compound of the formula: ##STR1## wherein --A is selected from the group consisting of ##STR2## wherein R 1 is independently C1-12 straight or branched alkyl...
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5336677 |
Substituted aminopyrimidines as antihypertensives
This invention relates to substituted 4-aminopyrimidines, which by virtue of their ability to antagonize angiotensin II are useful for the treatment of hypertension, congestive heart failure, and...
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5336436 |
Optically active oxirane derivatives, and their use as dopes in liquid-crystal mixtures
Optically active oxirane derivatives containing a mesogenic molecular unit are suitable as dopes in liquid-crystal mixtures. They give liquid-crystalline ferroelectric phases having short response...
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5334333 |
Electroactive compounds, compositions and devices and methods of making the same
The present invention relates to electroactive compounds capable of undergoing a change in light absorption and refraction due to an applied electric field and a permanent change in refraction due...
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5334614 |
Hydroxylamine derivatives
The invention concerns hydroxylamine derivatives of the formula I ##STR1## wherein R 4 is hydrogen, carbamoyl, (1-4C)alkyl, cyclopentyl, cyclohexyl, tetrahydrofuran-3-yl, tetrahydropyran-4-yl,...
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5328639 |
Fluoroalkane derivative, its composition and liquid crystal device using the same
A liquid crystal composition, comprising: at least one optically active mesomorphic compound having an asymmetric carbon atom to which a fluorine atom is directly bonded.
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5328637 |
Alkinyl-derivatives and their use in liquid crystalline mixtures
Compounds of the formula ##STR1## and liquid crystalline mixtures containing same.
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5326871 |
Optically active pyrimidine compound, process for producing the same and liquid crystal composition containing the same
An optically active pyrimidine compound represented by general formula (I): ##STR1## wherein R represents a fluoroalkyl group having 1 or 2 carbon atom(s), R 1 represents an alkyl group having...
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5326497 |
Nitrogen heterocycles and liquid crystalline mixtures containing them
Compounds of the general formula ##STR1## wherein R 1 is C 5 -12 -alkyl or C 5 -12 -alkenyl; R 2 is C 1 -9 -alkyl or C 2 -9 -alkenyl; provided that at least one of groups R 1 and R 2 is...
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5326762 |
Inhibitors of acyl-coenzyme A: cholesterol acyl transferase
Amides of the formula ##STR1## wherein R 1 and R 2 are independently heteroaryl, X-substituted heteroaryl, X-substituted phenyl, N-substituted triazinyl or N-substituted imidazolyl; and in...
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5326872 |
Process for preparation of asymmetric isoindoline pigments
This invention relates to a process for preparing asymmetric isoindoline pigments of the formula ##STR1## in which R 1 is an electron-withdrawing group, R 2 and R 3 are independently hydrogen,...
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5324450 |
Liquid crystalline compounds and process for production thereof
An optically active glycidyl ether, which is useful in making γ-lactone containing liquid crystalline compounds, the ether having the following formula: ##STR1## wherein R 1 is a group selected...
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5314891 |
Benzenesulphonamide derivatives
The invention concerns benzenesulphonamide derivatives of the formula I ##STR1## wherein R 1 is (1-4C)alkyl, (3-4C)alkenyl or (3-4C)alkynyl; R 2 and R 3 together form --A 2 --X 2 --A 3 --...
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5306718 |
Oxime and amine substituted azabicyclo and azocyclo muscarinic agonists and methods of treatment
Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds of the following general Formulas I, II and III are disclosed: ##STR1## Specifically the compounds are...
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5302597 |
2-substituted-4,6-di-tertiarybutyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
The present invention is novel compounds which are 2-substituted-4,6-di-tertiarybutyl-5-hydroxy-1,3-pyrimidines
and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical...
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5292737 |
N,N'-bis(sulfonamido)-2-amino-4-iminonaphthalen-1-ones and N,N'-bis(amido)-2-amino-4-iminonaphthalen-1-ones
N,N'-Bis(sulfonamido)-2-amino-4-iminonaphthalen-1-ones and N,N'-Bis(amido)-2-amino-4-iminonaphthalen-1-ones are disclosed. Methods of inhibiting protein kinase C activity which comprises contacting...
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5290477 |
Optically active compound and liquid crystal composition containing the same
An optically active compound represented by formula (I): ##STR1## wherein R 1 represents an alkyl group having from 3 to 9 carbon atoms; R 2 represents an alkyl group having from 3 to 7 carbon...
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5290931 |
Water-insoluble naphthalic acid imide dyestuffs
Water-insoluble naphthalic acid imide dyestuffs of the following formula: ##STR1## wherein D is ##STR2## wherein R 1 is C 1 -C 8 alkyl which may be substituted, R 2 is hydrogen, halogen, lower...
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5288428 |
Liquid crystal compounds having a terminal alkoxy propenyl group
Compounds having a terminal alkyloxypropenyl group of the general formula ##STR1## wherein rings A 1 and A 2 each independently represent unsubstituted or halogen-substituted 1,4-phenylene, in...
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5284949 |
2-substituted amino-4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines as antiinflammatory agents
The present invention is novel compounds which are 2-substituted amino-4,6-di-tertiarybutyl-5-hydroxy-1,3-pyrimidines and pharmaceutically acceptable acid addition or base salts thereof,...
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5283363 |
Process for the preparation of (hetero)arylalk(en/in)ylamines and (hetero)arylalkinylamines
The invention relates to a new process for the preparation of (hetero)arylalk(en/in)ylamines of the formula (I) ##STR1## in which A represents ethane-1,2-diyl (ethylene, dimethylene, --CH 2 --CH 2...
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5279762 |
Smectic liquid crystal phases
Compounds of the formula I R 1 --A 1 --A 2 --R 2 I wherein R 1 and R 2 are each alkyl with 1-15 C atoms, and wherein one or two non-adjacent CH 2 groups can also be...
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5278162 |
3,3'-disubstituted-1,3-dihydro-2H-pyrrolo[2,3-b]heterocyclic-2-one useful in the treatment of cognitive disorders of man
Compounds of Formula I have been shown to enhance the release of the neurotransmitters acetylcholine, dopamine and serotonin; and thus may be useful in the treatment of diseases of man where...
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5275756 |
Fluorine-containing optically active compound and liquid crystal composition containing the same
A fluorine-containing optically active compound represented by formula (I): ##STR1## wherein R 1 represents a straight chain alkyl or alkoxy group having from 6 to 14 carbon atoms or a...
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5271864 |
Ferroelectric liquid crystal compounds with cyclohexenyl cores and compositions containing them
Ferroelectric liquid crystal compounds and compositions containing cyclohexenyl derivatives are provided. Specifically provided are compounds of formula: ##STR1## wherein R 1 and R 2 can be an...
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5270467 |
5-substituted-2,4-diphenylpyrimidine derivatives
A compound is disclosed having the formula: ##STR1## wherein R 1 represents a halo-(C 1 to C 6 )-alkoxy group at the ortho or meta position, R 2 and R 3 , which may be either the same or...
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5270301 |
Fluoro-amide derivatives
The present invention relates to certain fluoro-amide derivatives, as described herein, which are human leukocyte elastase (HLE) inhibitors making them useful whenever such inhibition is desired,...
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5262416 |
Pesticidal substituted 2-[6-(pyrimidinyl)-indol-1-yl]-acrylic esters
Insecticidal and fungicidal substituted 2-[6-(pyrimidinyl)-indol-1-yl]-acrylic esters of the formula ##STR1## in which R 1 represents alkyl, or represents optionally substituted aralkyl, R 2 ...
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5262082 |
Ferroelectric liquid crystal compounds having perfluoroether terminal portions
Fluorine-containing liquid crystal compounds are provided. The compounds comprise a fluorocarbon terminal portion having at least one catenary ether oxygen and a hydrocarbon terminal portion, the...
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5260293 |
Pyrazines, pyrimidines and pyridazines useful in the treatment of senile dementia
The present invention provides pyrazines, pyridazines or pyrimidines, or salts or prodrugs thereof, substituted on one of the ring carbon atoms thereof with a non-aromatic azacyclic or azabicyclic...
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5260454 |
Bis-pyrimidyl thiol sulfenimide compounds
Heterocyclic thiol sulfenimide compounds are useful as an accelerator in the curing of natural and/or synthetic rubbers. The compound can be represented by the formula ##STR1## wherein each of A 1 ...
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5256682 |
Isoxazolylimidazole derivatives, process for their production and their use in pharmaceutical agents
4-Isoxazolyl-imidazole derivatives of formula I ##STR1## in which R 1 , R 2 , R 3 and R 4 have the meanings indicated, as well as their production and use in pharmaceutical agents, are described.
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5254557 |
Compound and treatment
A compound of formula (IA) in the form of a pharmaceutically acceptable microfine powder is disclosed. ##STR1##
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5250532 |
3,4,N-trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides
3,4,N-triaryl-4,5-dihydro-1H-pyrazole-1-carboxamide compounds having an aryl moiety in the 4-position that is an optionally substituted pyridinyl, pyrimidinyl, pyridazinyl, pyrazinyl, or quinolinyl...
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5250530 |
Aminopyrimidine derivatives, and their use as fungicides
Aminopyrimidine derivatives, their preparation, and agents containing them, and their use as fungicides comprising ##STR1## in which R 1 is alkyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl, alkenyl,...
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5248776 |
Process for enantiomerically pure β-L-1,3-oxathiolane nucleosides
An asymmetric process for the preparation of enantiomerically pure β-L-(-)-1,3-oxathiolane-nucleosides that includes the initial preparation of the key chiral intermediates (2R,5R) and...
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5238937 |
Pyridaziny or oxodihydropyridazinyl chroman derivatives
The invention relates to novel chroman derivatives of the formula I ##STR1## in which R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and R 9 have the meanings given in [Patent claim 1], and which,...
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