Matches 101 - 150 out of 627 < 1 2 3 4 5 6 7 8 9 10 11 12 13 >
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6274734 Process for making pyrimidine derivatives  
The present invention provides a process for the manufacture of pyrimidines of formula I: ##STR1## wherein R 1 , R 2 , R 3 each independently represent hydrogen, C 1 -7 -alkyl, or C 1 -7...
6265404 Benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives and their use as anti-coagulants  
This invention is directed to benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives which are useful as anti-coagulants. This invention is also directed to...
6254669 Bleed reduction agents for ink printing inks  
A compound of the Formula (1) and salts thereof: ##STR1## wherein: Ar, Ar 1 , J, J 1 , X, X 1 W, W 1 , L and m are as defined in the description. The compounds of Formula (1) are useful as...
6245256 Chiral swallow-tailed liquid crystals and its fabrication method  
Novel chiral swallow-tailed liquid crystals synthesized from chiral material comprised of alkyl(s)-2-{6-[4-(4'-alkyloxyphenyl)benzoyloxy]-2-naphthyl}p ropionates having a rigid core, a chiral...
6242600 2-piperazinone-1-acetic acid derivatives and their use  
The present invention provides compounds and medicines effective for prophylaxis and therapy of various diseases by controlling or inhibiting cell-adhesion. Especially, the compounds of this...
6235903 Method for preparing sulfanyl-type endothelin receptor antagonists  
A process for preparing endothelin receptor antagonists of the sulfanyl type of the general formula I ##STR1## by nucleophilic reaction of a carboxylic acid derivative of the formula II with a...
6221871 Certain aminomethyl biphenyl, aminomethyl phenyl pyridine and aminomethyl phenyl pyrimidine derivatives; novel dopamine receptor subtype selective ligands  
Disclosed are compounds of the formula: ##STR1## where S and V are various organic or inorganic substituents; G and K are the same or different and represent N or CR' where R' is an organic...
6211216 Isoxazolyl- and isoxazolinyl-substituted benzoylcyclohexanediones, process for their preparation and their use as herbicides and plant growth regulators  
Isoxazolyl- and isoxazolinyl-substituted benzoylcyclohexanediones, process for their preparation and their use as herbicides and plant growth regulators. Benzoylcyclohexanediones of the formula...
6191149 Heterocyclic derivative and medicine  
A pharmaceutical composition comprising a compound of the following general formula [I] or its salt. ##STR1## wherein R 1 represents aryl or a heteroaromatic group. R 2 represents hydrogen,...
6180637 1,2,5-trisubstituted 1,2-dihydroindazol-3-ones having anti-asthmatic, anti-allergic, anti-inflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments  
The invention relates to 1,2,5-trisubstituted 1,2-dihydroindazol-3-ones of formula (I) ##STR1## wherein X is --SO 2 --, --SO--, --(CH 2 ) p --, --(CH 2 ) p --O--, --(CH 2 ) p --(CO)--,...
6177154 Alkoxybenzene derivative, liquid-crystal composition, and liquid-crystal display element  
Disclosed are (a) liquid crystalline compounds which are essential as component of the liquid crystal compositions, are excellent in miscibility with other liquid crystal compositions,...
6174901 Substituted pyridine and pyridazine compounds and methods of use  
Selected novel substituted pyridine and pyridazine compounds are effective for prophylaxis and treatment of diseases, such as TNF-α, IL-1β, IL-6 and/or IL-8 mediated diseases, and other maladies,...
6172226 Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions  
A method is disclosed for preparing novel PNA synthons having protecting groups capable of removal under mild conditions. The PNA synthons are prepared by coupling novel N-substituted nucleobase...
6169181 Compounds useful to treat retroviral infections  
The present invention relates to compounds of formula I and II which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4-hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives...
6162809 Pyridylthio compounds for controlling helicobacter bacteria  
Pyridinylthiomethyl- and pyrimidinylthiomethyl-pyridines and their pharmacologically-acceptable compositions are useful for controlling Helicobacter bacteria and for treating those afflicted with...
6162808 Compounds  
6159392 5,7-difluoro-1,2,3,4-tetrahydronaphthalene derivatives and their use thereof in liquid crystal mixtures  
5,7-Difluoro-1,2,3,4-tetrahydronaphthalene derivatives of the formula (I) R 1 (-A 1 -M 1 ) a (-A 2 -M 2 ) b -B(-M 3 -A 3 ) c (-M 4 -A 4 ) d -R 2 (I) in which B is and ##STR1##...
6156766 Benzamide compounds and pharmaceutical use thereof  
Benzamide compounds of the formula ##STR1## wherein each symbol is defined in the specification, isomers thereof and pharmaceutically acceptable acid addition salts thereof. Pharmaceutical...
6153560 Pyrimidyl phenyl and benzyl ethers, process and intermediate products for their production and their use as herbicide  
Pyrimidyl phenyl and pyrimidyl benzyl ethers of the general formula I ##STR1## and their salts and N-oxides, where the substituents and indices have the following meanings: Q is (CO 2 CH 3...
6143198 Liquid crystalline compounds having exo-methylene site and liquid crystal compositions comprising the same  
A liquid crystalline compound represented by the general formula (1) ##STR1## wherein R 1 represents an alkyl or alkoxy group having 1 to 10 carbon atoms, a cyano group, a halogen atom, or an...
6140354 N-substituted aminotetralins as ligands for the neuropeptide Y Y5 receptor useful in the treatment of obesity and other disorders  
β-Aminotetralin derivatives of the formula: ##STR1## which are ligands for the neuropeptide Y Y5 (NPY5) receptor, methods of preparation and pharmaceutical compositions containing a...
6136971 Preparation of sulfonamides  
The present invention provides a process for preparing 1,2-diheteroethylene sulfonamide of the formula: ##STR1## by reacting a pyrimidine monohalide of the formula: ##STR2## with a mono-protected...
6133280 Androgen synthesis inhibitors  
This invention relates to novel inhibitors of androgen synthesis that are useful in the treatment of prostate cancer and benign prostatic hypertrophy. The present invention also provides methods of...
6121431 Nucleoside derivatives  
6114342 2-(O-[pyrimidin-4-yl]methylenoxy)phenylacetic acid derivatives and their use for controlling harmful fungi and animal pests  
2-(O-[pyrimidin-4-yl]methylenoxy)phenylacetic acid derivatives of the general formula I and the salts and N-oxides thereof where the radicals R 1 to R 4 and Q have the following meanings: R 1 is...
6114328 Isoxazoline and isoxazole fibrogen receptor antagonists  
This invention relates to novel isoxazolines and isoxazoles which are useful as antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex or the vitronectin receptor, to...
6103898 Preparation of cyclic urea derivatives  
Cyclic urea derivatives of the formula I ##STR1## in which X, X', Y, Y' and Z can have various meanings, are prepared by a) reacting a urea derivative of the formula II ##STR2## with a diketone of...
6093345 Optically active compound, liquid crystal composition containing the same, and liquid crystal electro-optic element using the same  
An optically active compound represented by formula (I): wherein A represents ##STR1## wherein R 2 represents an alkyl group having from 8 to 12 carbon atoms; R 1 represents a straight chain...
6093718 Substituted pyrimidine derivatives and their pharmaceutical use  
This invention concerns heterocyclic derivatives which are useful in inhibiting oxido-squalene cyclase, processes for their preparation and pharmaceutical compositions containing them. The present...
6093716 Substituted 2-pyrimidineamines and processes for their preparation  
Compounds of general formula (1): ##STR1## are described wherein Het is an optionally substituted heteroaromatic group; R 1 is a hydrogen atom or a straight or branched chain alkyl group; R 2 is...
6083955 Arylethenesulfonamide derivatives and drug composition containing the same  
Novel arylethenesulfonamide derivative having a high affinity for drugs, especially endoserine receptors, and represented by general formula (I); pharmaceutically acceptable salts thereof; and...
6069250 Method and compositions for the synthesis of dioxolane nucleosides with β-configuration  
The present invention relates to methods and compositions for preparing biologically important nucleoside analogues containing 1,3-dioxolane sugar rings. In particular, this invention relates to...
6066734 Chloropyrimidine process  
Chloropyrimidine compounds, such as 4,6-dichloro-2-ethoxypyrimidine, were prepared in good yield and good purity from the corresponding hydroxypyrimidine compounds in the absence of organic...
6063786 Heterocyclic compounds having MMP and TNF inhibitory activity  
Compounds of formula (I) ##STR1## are useful as therapeutic agents, by virtue of having MMP and TNF inhibitory activity.
6051288 Fluorine-substituted liquid-crystal compound, liquid-crystal composition and liquid-crystal display device  
6040442 Process for preparing 1,2,5-thiadiazole containing ethers  
The presently claimed process provides a method for preparing compounds of the formula ##STR1## phosphorous (III) compound and a diester of azodicarboxylate.
6030546 Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition  
The present invention relates to trans-olefin compounds represented by the general formula (1) useful as an ingredient of liquid crystal composition, trans-olefin compounds useful as intermediate...
6013651 Meta-azacyclic amino benzoic acid compounds and derivatives thereof  
The present invention is directed to compounds of the formula ##STR1## and pharmaceutically acceptable salts and isomers thereof.
6010642 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same  
Disclosed is to provide an azine derivative as a novel liquid crystal compound, a novel process for the preparation of an asymmetrical azine in a high reaction yield with an extremely small amount...
6008160 Substituted 1-amino-3-phenyluracil derivatives, their preparation and their use as herbicides  
The invention relates to novel substituted aminouracils of the general formula (I) ##STR1## in which R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are each as defined in the claims, to the...
6004933 Cysteine protease inhibitors  
The present invention relates to cysteine protease inhibitors of the general formula (I): ##STR1## wherein Z is a cysteine protease binding moiety; X and Y are S, O or optionally substituted N; and...
6001838 Process for the separation of pyrimidine derivatives from aqueous solutions  
A process for the separation and purification of pyrimidine derivatives, such as tetrahydropyrimidines, in particular 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acids (ectoine) from aqueous...
5994356 Carboxylic acid derivatives, medicaments comprising these compounds, their use and processes for their production  
The present invention relates to carboxylic acid derivatives of the general formula ##STR1## in which R a to R c , A, B, D, E and X 1 to X 3 are as defined in claim 1, their tautomers, their...
5976408 Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device  
An acrylonitrile derivative expressed by the following general formula I, a composition comprising the derivative and having an improved viscosity and optical anisotropy, and a liquid crystal...
5972949 Ether compounds and their use  
There are disclosed novel ether compounds of the general formula: ##STR1## wherein R 1 , R 2 and R 3 are each hydrogen or the like; A is a group of the general formula: ##STR2## B is a group of...
5965059 Optically active compound, antiferroelectric liquid crystal composition containing the same, process for producing the same and process for producing an optically active carboxylic acid  
An optically active compound which itself generally exhibits no antiferroelectric liquid crystal phase, but which can be added to an antiferroelectric liquid crystal or composition thereof having a...
5952354 Tris carbamic acid esters: inhibitors of cholesterol absorption  
Inhibition of the enzymes cholesterol ester hydrolase (CEH) and/or acyl coenzyme A: cholesterol acyltransferase (ACAT) results in the inhibition of the esterification of cholesterol and are...
5932740 Thioheterocyclic near-infrared dyes  
Disclosed is a novel near-infrared absorbing dye of formula: ##STR1## wherein X 1 , X 2 independently represents --CR 8 R 9 --, --S--, --Se--, --NR 10 --, --CHCH-- or --O--; n is an integer...
5929075 Apolipoprotein-B synthesis inhibitors  
The present invention provides novel compounds of formula ##STR1## the N-oxides, the stereochemically isomeric forms thereof, and the pharmaceutically acceptable acid addition salts thereof,...
5925644 Substituted nitrogen heterocycles, processes for their preparation and their use as pesticides  
Compounds of the formula I ##STR1## in which A is CH and D is N + R, A is nitrogen and D is N + R or A is N + R and D is nitrogen, R is --CR 4 R 5 --E--R 6 , Q n - is an inorganic or organic...
Matches 101 - 150 out of 627 < 1 2 3 4 5 6 7 8 9 10 11 12 13 >