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4292312 |
Method for preparing alloxan stable aqueous solutions and solutions resulting therefrom
Stable aqueous injectable solutions comprising alloxan stabilized with a reducing sugar selected from the group consisting of levulose, glucose and lactose are disclosed.
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4288147 |
Electro-optical composition of the guest-host type
The electro-optical composition comprises a host liquid crystal and guest dichroic dye which is characterized generally as a linear, noncondensed aromatic compound including one or more quinonoid...
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4288442 |
Inhibiting adrenergic β-receptors with piperidinopropyl derivatives
A piperidinopropyl derivative of the formula ##STR1## in which R 1 and R 2 each independently is hydrogen or a lower alkyl radical, or together are an alkylene radical, R 3 is hydrogen,...
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4287342 |
2,4,6-Trihalo-5-alkyl-and 5-alkenylsulphonylpyrimidines
There are described compounds of the formulae I and II ##STR1## and also salts of compounds of the formula I, wherein X represents optionally substituted alkyl or alkenyl, and the Y's represent...
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4269873 |
2-, 5-, and 6-Substituted-1-carbadethiapen-2-em-3-carboxylic acids
Disclosed are 2-, 5- and 6-substituted-1-carbadethiapen-2-em-3-carboxylic acids having the structure: ##STR1## wherein R 6 , R 7 , R 8 and R 9 are, inter alia, independently selected from the...
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4213899 |
Reactive dyestuffs containing chlorine or fluorine substituents and one or more pyridine radicals linked to the dyestuff at the 2-, 4- or 6-position
A dyestuff of the formula ##STR1## where D is a chromophoric residue n is 1 or 2 Z is ##STR2## where R is H, C 1 -4 alkyl, C 1 -4 alkyl substituted by OH, OSO 3 H, CN or SO 3 H or is phenyl...
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4210583 |
Azo dyes of the 2,6-di(substituted) amino pyridine series
An azo dye of the general formula ##STR1## where A is cyano or carbamoyl, R is hydrogen, alkyl or phenyl, R 1 is hydrogen, bromine, chlorine or nitro, R 2 is hydrogen, chlorine, bromine,...
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4196288 |
Ergoline derivatives and a process for their preparation
New ergoline derivatives are disclosed which are compounds of formula (I) having the structure: ##STR1## wherein R 1 is hydrogen or methoxy; R 2 is hydrogen or methyl; and X is hydroxy, R 3 COO,...
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4188483 |
5-Alkylsulphonyl- and 5-alkenylsulphonylbarbituric acids and derivatives thereof
There are described compounds of the formulae I and II ##STR1## and also salts of compounds of the formula I, wherein X represents optionally substituted alkyl or alkenyl, and the Y's represent...
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4179562 |
2,4-Diamino-5-alkyloxy-pyrimidines
Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof and antimalarial and antibacterial compositions containing an effective amount of active agent and a pharmaceutically...
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4166852 |
Piperazino-pyrimidines and their use as spasmolytic agents
The compounds of the formula: ##STR1## in which R represents a methyl or methylthio group, X represents a halogen atom or an alkoxy group containing 1 to 5 carbon atoms, Y represents an acylamino...
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4152426 |
Pesticidally active O-alkyl-O-[1,6-Dihydro-1-substituted-6-oxo-pyrimid in-4-yl]-(thiono) (thiol) phosphoric (phosphonic) acid esters and ester-amides
O-alkyl-O-[1,6-dihydro-1-substituted-6-oxo-pyrimidin-4-yl]-(
thiono) (thiol) phosphoric (phosphonic) acid esters and ester-amides of the formula ##STR1## in which R represents alkyl, R 1 ...
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4147789 |
6-Methyl-8-thiomethyl-ergolene derivatives
This invention provides new compounds of formula I, ##STR1## wherein X Y IS THE GROUP ##STR2## and R is hydrogen, cyano, a 5- or 6-membered unsaturated heterocyclic radical attached through a ring...
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4061643 |
Certain 16-aryloxy-11,12-seco-prostaglandins
This invention relates to aryloxy-, alkoxy-, arylthio-, and alkylthio-11,12-seco-prostaglandins and to processes for their manufacture. These compounds have prostaglandin-like activity and are...
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4059548 |
Hexahydropyrimidine-1,3-diacetonitriles and processes for preparing the same
N,N'-Dicarboxymethyl-1,3-propanediamine (designated PDDA) is prepared by reacting 1,3-propanediamine with formaldehyde and HCN to form hexahydropyrimidine-1,3-diacetonitrile, which is hydrolyzed...
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4058528 |
5-Hydroxyhexahydropyrimidine
N,N'-Dicarboxymethyl-1,3-propanediamine (designated PDDA) is prepared by reacting 1,3-propanediamine with formaldehyde and HCN to form hexahydropyrimidine-1,3-diacetonitrile, which is hydrolyzed...
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4052386 |
Reactive phthalocyanine dyestuffs containing a fluoropyrimidinyl group
Reactive dyestuffs of the formula ##STR1## in which D is the residue of an organic dyestuff, R is hydrogen or a lower alkyl, R 1 is hydrogen or a substituent, R 2 is hydrogen, halogen,...
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4051244 |
2,4-Diamino 5-bromo 6-chloro pyrimidines, process for their preparation and use as pharmaceuticals
Compounds of the general formula ##STR1## wherein R 1 and R 3 represent hydrogen or alkyl containing 1 to 4 carbons; R 2 and R 4 represent hydrogen, alkyl containing 1 to 8 carbons,...
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4027027 |
Pyridyloxyalkyleneamino-phenoxy-propanol-2-compounds
Compounds of the formula ##STR1## WHEREIN Ar 1 and Ar 2 denote an optionally substituted aromatic hydrocarbon radical or a monocyclic, monoazacyclic or diazacyclic radical of aromatic character...
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3996228 |
Pyrimidinoaminoethyl ergoline derivatives
Pyrimidinoaminoethyl ergoline derivatives of the formula: ##STR1## wherein R is hydrogen or methyl; R 1 and R 2 are independently selected from the group consisting of hydrogen, alkyl having 1 to...
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3984411 |
Pyrimidines
Compounds having the formula ##SPC1## Process for the preparation of such compounds which comprises reacting a pound having the formula: ##SPC2## Medicaments containing a compound of formula (I) or...
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3968214 |
5-Methylthio-pyrimidine vasodilators
The compounds of the formula: ##SPC1## In which Y represents a chlorine atom or an alkoxy, dialkylaminoalkoxy, pyridylalkoxy group, R 1 and R 2 are identical or different substituents and...
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3966732 |
Nitroimidazolyl pyrimidines
Nitroimidazolyl pyrimidines of the formula ##SPC1## And physiologically acceptable acid addition salts thereon wherein X is alkyl of 1-4 carbon atoms, R 1 and R 2 each are a hydrogen atom, alkyl...
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3957785 |
Bβ-Pyrimidino-aminomethyl-10α-ergoline and 10α-methoxyergoline derivatives
Novel 8β-pyrimidino-aminomethyl-10α-ergoline and 10α-methoxyergoline derivatives which possess a high and prolonged adrenolytic activity and a low toxicity, and some of which also possess...
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3941804 |
1-Heteroarylsulphonyl-2-imino-imidazolidines
Compounds of the class of 1-heteroarylsulphonyl-2-imino-imidazolidines which are substituted in the 3-position by an aliphatic or cycloaliphatic hydrocarbon radical, especially a cycloalkyl...
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3941786 |
Process for the production of 4-hydroxy-6-hydroxymethylpyrimidine
Process for the production of 2-R 1 substituted-4- hydroxy-5-R 2 substituted -6-hydroxy methyl-pyrimidines having the following general formula: ##EQU1## wherein R 1 can be an alkyl group, a...
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3926994 |
Heterocyclic compounds
The disclosure relates to derivatives of tetrahydropyrimidine, imidazoline, tetrahydro-1H-1,3-diazepine and hexahydro-1,3-diazocine of the general formula ##SPC1## Or an acid addition salt thereof...
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3927023 |
Imidazolyl benzofurans
Imidazolyl and tetrahydropyrimidyl benzofurans of the formula: ##SPC1## Are disclosed. In the above structure A, B, and C are hydrogen or lower alkyl of 1 to 6 carbon atoms, halogen, lower alkoxy...
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3920655 |
Nitroimidazolyl benzoquinazolines
Nitroimidazolyl pyrimidines of the formula ##SPC1## And physiologically acceptable acid addition salts thereof wherein X is alkyl of 1-4 carbon atoms, R 1 and R 2 each are a hydrogen atom, alkyl...
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3907797 |
5-(3-Iodinepropargyloxy)pyrimidines
(Iodinepropargyloxy)-pyrimidines of the general formula ##EQU1## wherein R is selected from among hydrogen, alkyl, alkoxy, alkylthio, alkylsulfinyl and alkylsulfonyl radicals are described, and a...
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3883529 |
NEW CELLULOSE REACTIVE DYESTUFFS
Reactive dyestuffs of the triphenylmethane or xanthene series having the formula: ##SPC1## Wherein R 1 represents H or an alkyl group and R 2 represents an alkyl, aryl or substituted aryl group,...
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3862190 |
5-(UNSUBSTITUTED AND SUBSTITUTED PHENOXY)-4-AMINO PYRIMIDINES
The preparation of novel 5-(substituted phenoxy)-4-amino and substituted amino pyrimidines is described. These compounds, possessing anti-secretory an;d anti-ulcer activity, are effective...
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3846428 |
NITROFURYLPYRIMIDINES
Compounds of the formula Wherein R is saturated or unsaturated, straight-chain or branched hydrocarbon aliphatic group of 1-6 carbon atoms or cyclic alkyl of 3-7 carbon atoms, alkyl of 1-6 carbon...
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3843656 |
2-METHYLAMINO-4'-METHYL-4-PIPERAZINYL-6-CHLORO-5-METHYLTHIO-PYRIMIDINE, SALTS THEREOF, AND PROCESS FOR THEIR PREPARATION
The compound of the formula: ##SPC1## Salts of this compound and process for the preparation of the compound which comprises condensing one mole of 2,4,6-trichloro-5-methylthio-pyrimidine with 1...
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3817998 |
2-AMINO AND SUBSTITUTED AMINO-4, 6-DIAMINO-5-PYRIMIDINESULFONAMIDES
2-Amino and substituted amino-4,6-diamino-5-pyrimidinesulfonamides, e.g., 4,6-diamino-2-methylamino-5-pyrimidinesulfonamide, are prepared by treating...
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3755312 |
6-SUBSTITUTED-1, 2,4-PYRIMIDO[4,5-E]THIADIAZINE-1,1-DIOXIDES
Substituted 8-amino 1,2,4-pyrimido[4,5-e]-thiadiazines-1,1-dioxides, e.g., 8-amino-3-ethyl-6-methylthio-1,2,4-pyrimido[4,5-e]thiadiazin
e-1,1-dioxide, are prepared from substituted...
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3621022 |
ANTIBACTERIAL 5-NITROFURYL-PYRIMIDINES
Novel 5-nitrofuran derivatives and the physiologically acceptable salts thereof having the formula: ##SPC1## Wherein R 1 and R 2 each represent hydrogen, hydroxyl, lower alkyl, alkoxy, amino or...
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3549654 |
1,1'-ALKYLENE-BIS(3,3-DICHLORO-2-PYRROLIDINONES)
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3528967 |
N1-ACETYL-N1-(CYCLOPROPYL-4-PYRIMIDINYL)-SULPHANILAMIDES
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3511837 |
4-PYRIMIDYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND THEIR PRODUCTION
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3464987 |
1,2-DIHYDRO-1-HYDROXY-2-IMINO-6-(LOWER ALKYL)PYRIMIDINES
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3457278 |
CYCLOPROPYL-4-SULFANILAMIDO-PYRIMIDINES
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3435035 |
PYRIMIDINE SULFONES
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3431263 |
CERTAIN 2-BENZENESULFONAMIDO-5-OXYPYRIMIDINES
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3422098 |
SULFANILAMIDO-PYRIMIDINES
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3382248 |
6-amino-4, 5-di(substituted amino)-1, 2-dihydro-1-hydroxy-2-iminopyrimidines
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3337543 |
Novel method of preparing 1, 3-diazaphenothiazines
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3331841 |
Certain derivatives of 2-amino-5-alkoxypyrimidine
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3322767 |
Tham salts
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3317536 |
4-benzenesulfonamido-pyrimidine derivatives
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