Matches 101 - 150 out of 198 < 1 2 3 4 >
Match Document Document Title
5011842 2-(heterocyclylalkyl)imidazopyridines for treating allergic diseases  
2-(Heterocyclylalkyl)imidazopyridines having antihistaminic properties, compositions containing these compounds as active ingredient and novel 2-(Heterocyclylalkyl)imidazopyridines.
4995899 Optically active diazabicycloalkane derivatives and their use for protecting crops from the phytotoxic effect of herbicides  
Diazabicycloalkane derivatives of the formula ##STR1## where R is alkyl, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are identical or different and independently of one another are each...
4970307 Process for formation of base and light-sensitive material  
A process for formation of a base from a base precursor, which comprises decomposing the base precursor in the presence of a catalyst. The base precursor has the following formula (I) or (II): (R...
4943580 Anti-histaminic benzimidazole, imidazopyridine and purine derivatives  
Novel 1-alkyl substituted benzimidazole derivatives and their pharmaceutically acceptable acid addition salts having anti-histaminic properties, compositions containing the same, and methods of...
4943633 Catalytic preparation of cyanoalkyl lactams  
This invention relates to an improved process for the preparation of cyanoalkyl lactams by the reaction of an unsaturated nitrile with a lactam, said cyanoalkyl lactam of the formula ##STR1##...
4927829 Heterocyclic compounds and antiulcer agents  
Novel heterocyclic compounds of the formula: ##STR1## or pharmaceutically acceptable acid addition salts thereof having a more potent and longer lasting cytoprotective anti-ulcer action than known...
4921527 Herbicidal sulfonamides  
The invention relates to sulfonylurea compounds with a substituted or unsubstituted bicyclic nine-membered ring having one to five heteroatoms which are preemergent and/or postemergent herbicides...
4869772 Diazabicyclo and triazabicyclo primer compositions and use thereof in bonding non-polar substrates  
In a process for priming a non-polar substrate such as a polyolefin for bonding with a cyanoacrylate adhesive, the use of an adhesion-promoting primer comprising at least one diazabicyclo or...
4861779 Anti-bacterial substituted bridged-diazabicycloalkyl quinolone carboxylic acids  
Antibacterial compounds have the formula ##STR1## wherein R 1 is hydrogen, a pharmaceutically acceptable cation, or alkyl; A is CH, CF, CCl or N; Y is alkyl, haloalkyl, cyclopropyl, vinyl,...
4840953 9-(Substituted thio)-4H-pyrido[1,2,-A]pyrimidin-4-one derivatives  
9-(Substituted thio)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives of the formula: ##STR1## wherein n is 0 or 1, R is --COR 1 , --CONR 4 R 5 or --CH 2 R 6 , R 1 is C 1 -C 5 alkyl, C 3 -C 7 ...
4816459 Tetrazolyl-substituted pyrido[1,2-a]pyrimidines and use as SRS-A antagonists  
Pyrido[1,2-a]pyrimidine derivatives of the general formula [I] and their physiologically acceptable salts are provided: ##STR1## where R is a hydrogen atom, a halogen atom or a methyl group, and n...
4804663 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles  
3-Piperdinyl-1,2-benzisothiazoles and 3-piperidinyl-1,2-benzisoxazoles and their pharmaceutically acceptable acid addition salts having useful antipsychotic properties and being useful in the...
4798832 Pyrido[1,2-a]pyrimidine compounds, corresponding intermediates and use as SRS-A antagonists  
Pyrido[1,2-a]pyrimidine derivatives of the general formula [I] and their physiologically acceptable salts are provided: ##STR1## where R is a hydrogen atom, a halogen atom or a methyl group, and n...
4794120 Antiparasitic nitrofuran derivatives  
Nitrofuran derivatives of formula (I) ##STR1## in which n is 0 or 1 and R is a selected heterocyclic radical have useful antibacterial, antiparasitic and antifungal activity.
4791199 Process for antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones  
This invention relates to a process for preparing useful antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones from 1-acyl-α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-2-pip erid ineacetamides....
4760065 Trifluoromethyl substituted tetracyclic quinazolin-ones having tranquilizing activity  
Trifluoromethyl substituted tetracyclic compounds including optical isomers thereof having the formula: ##STR1## wherein n is 1 or 2 and p is 0 or 1, are useful as CNS agents with tranquilizing...
4716169 Imidazo[1,2a]pyridines and their use as cardiotonic agents  
The invention relates to new imidazo derivatives of the formula ##STR1## wherein "A-D and R 1 -R 3 are as defined in the specification". The new compounds have valuable pharmacological...
4683233 Salts of 2-keto-2H, 3H-1,2-benzisothiazole 1,1-dioxide as microbicides  
A method of combating fungi and bacteria which comprises applying to such fungi, bacteria or a habitat thereof, a fungicidally or bactericidally effective amount of at least one salt of 3-keto-2-,...
4680295 Octahydropyrido[1,2-c]pyrimidinones and hexahydropyrido[1,2-c]pyrimidinediones  
This invention relates to octahydropyrido[1,2-c]pyrimidinones and hexahydropyrido[1,2-c]pyrimidinediones that are useful as inhibitors of cardiac arrhythmias and are therefore useful in the...
4581171 [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders  
Novel [[bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones, wherein the pyrimidinone-ring is embraced within a bicyclic system, being useful compounds in the treatment of psychosomatic disorders.
4565815 Pyrazolo[1,5-a]-1,3,5-triazines  
A compound having anti-ulcer activity and having the formula ##STR1## wherein D is H, SH, NH 2 , OH, R 4 S where R 4 is a lower alkyl group; E is OH or NH 2 ; J is H or aryl; X is CH or N; Y is...
4560754 Substituted 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]decan-4-ones and 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]dec-2-en-4-ones  
This invention relates to 5-(substituted phenyl)-5-[(substituted amino)alkyl]-1,3-diazabicyclo[4.4.0]decan-4-ones and 5-(substituted phenyl)-5-[(substituted...
4551457 Substituted thiazolo[3,2-a]pyrimidines and process for their preparation  
Pharmacologically active thiazolo[3,2-a]pyrimidines of the formula ##STR1## wherein A is a bond between the α- and β-carbon atoms or (--CH 2 --) group; R 1 and R 2 represent hydrogen, C 1 -C...
4529721 Vinylthioacetamido oxacephalosporin derivatives  
A compound of the formula: ##STR1## wherein u represents hydrogen, carboxamido, N-hydroxycarboxamido, carboxy, azido, an aryl, an acylamino, a protected carboxy or an N-alkoxycarboxamido, or,...
4495189 Condensed pyrimidines  
New compounds of the following formula are disclosed: 1,6-dimethyl-3-carbamoyl-4-oxo-1,6,7,8-tetrahydro-4H-pyrido( 1,2-a)-pyrimidi ne; ...
4490293 2,5,6,8,9-Penta-alkyl or penta-aralkyl-substituted 1,3,7-triazabicyclo(3,3,1) non-3-enes and trialkyl or triaralkyl-substituted tetrahydropyrimidines  
This invention relates to the preparation of penta-alkyl (or aralkyl)-substituted 1,3,7-triazabicyclo (3,3,1) non-3-enes (TBN's) and trialkyl (or aralkyl)-substituted tetrahydropyrimidines (THP's)...
4482557 3-Substituted-2-oxo-tetrahydro-pyrrol[1,2-a]pyrimidines having digitalis-like activity  
New 3-substituted-2-oxo-tetrahydro-pyrrolo[1,2-a]pyrimidines of the formula (II) ##STR1## or a pharmaceutically acceptable acid addition or quaternary ammonium salts thereof are disclosed, wherein ...
4474953 Process and intermediates for the preparation of 3(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-ones  
A process for preparing compounds of the formula ##STR1## wherein R 1 , R 2 , R 3 and R 4 are independently selected from the group consisting of H, an alkyl group containing 1 to about 4 carbon...
4461769 Nitrogen bridgehead compounds having anti-allergic effect  
Compounds of the formula I ##STR1## or pharmaceutically acceptable salts, hydrates, stereoisomers, optically active isomers, geometrical isomers or tautomeric forms thereof are disclosed wherein ...
4460771 Antiphlogistic and anticoagulant condensed pyrimidine derivatives  
New optionally racemic or optically active pyrimido(1,2a) heterocyclic compounds of the formula ##STR1## wherein m is 0, 1 or 2, n is 0, 1 or 2, R is an alkyl group containing one to six...
4456752 Process for the preparation of 9-hydrazono-6,7,8,9-tetrahydro-4H-pyro[1,2-a]pyrimidine-4-one compounds, the salts and hydrates thereof  
A process for the preparation of nitrogen bridgehead condensed pyrimidine compounds of the general formula ##STR1## [wherein R represents hydrogen or lower alkyl; R 1 represents hydrogen, lower...
4452982 Process for the preparation of nitrogen-bridgehead condensed pyrimidine compounds, and pharmaceutical compositions containing them  
A process is disclosed for the preparation of compounds of the formula (I) ##STR1## wherein R 1 and R 2 are each hydrogen or lower alkyl; R 3 is carboxy, lower alkoxycarbonyl, carbamoyl,...
4421914 Thiazolo[3,2-a]pyrimidines, derivatives thereof, processes for production thereof, and pharmaceutical use thereof  
A compound selected from thiazolo[3,2-a]pyrimidines or their enolate derivatives represented by the following general formula ##STR1## wherein R 1 and R 2 are identical or different, and each...
4404205 2-Oxo-2,6,7,8,9,10 hexahydro-pyrimido[1,2-a]azepines and antianginal method of use thereof and of 4-oxo-4,6,7,8,9,10-hexahydropyrimido[1,2-a]azepines  
3 Substituted hexahydro-pyrimido[1, 2 a]azepines and quaternary derivatives, useful as antianginals are prepared. Specifically tested are 3 carboxylates and carbo hydrazides. 3 Cyano Carbamonyl and...
4395551 Pyridopyrimidinone compounds  
A compound of the formula ##STR1## wherein R and R 1 together form a 1,3-butadien-1,4-diyl group optionally substituted with a methyl or chloro group and R 2 is halogen is disclosed. The compound...
4367229 3-Substituted-tetrahydro-pyrrolo[1,2-a]pyrimidines and pharmaceutical compositions  
Chemical compounds having an effect on the circulatory system have the formulas ##STR1## or a mixture thereof, or a pharmaceutically suitable acid-addition salt or quaternary salt thereof, wherein ...
4342870 Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives  
Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives, wherein the piperidine ring is substituted with an aroyl radical or a functional derivative thereof, said compounds being...
4341780 Substituted pyrido [1,2-a] pyrimidines useful as anti-allergic, anti-ulcer and anti-diabetic agents  
Substituted pyrido [1,2-a] pyrimidines and pharmaceutical compositions containing them, suitable for use as anti-allergy, anti-ulcer, and anti-diabetic agents.
4325954 Pyrrolopyrimidinones and pyrroloimidazolones and their compositions and therapeutic methods  
The present invention relates to compounds having the formula: ##STR1## in which: n is equal to 1 or 2, R 1 represents a hydrogen atom and R 2 represents a phenyl group or a benzofuryl group;...
4321377 Substituted-4-oxo-1,6,7,8-tetrahydro-4H-pyrido[1,2-a]pyrimidines  
Nitrogen bridgehead compounds (pyrido-[1,2-a]-pyrimidine derivatives) which are useful intermediates in the making of known compounds of this class and which themselves possess PG-antagonist,...
4310526 Substituted 6,7-methylene pyrido[1,2-a]pyrimidines useful as anti-allergic and anti-ulcer agents  
Substituted 6,7-methylen[1,2-a]pyrimidines and pharmaceutical compositions containing them, suitable for use as anti-allergic, anti-ulcer and anti-diabetic agents.
4291036 Pyrido[1,2-A]pyrimidine derivatives and method of analgesic treatment  
Compounds of the formula ##STR1## or pharmaceutically acceptable acid-addition or quaternart ammonium salts thereof wherein R is hydroxy, carboxy, lower alkoxycarbonyl, benzyloxycarbonyl,...
4288438 Nitrogen-containing heterocyclic ring derivatives and analgesic and anti-inflammatory compositions and methods employing them  
Novel nitrogen-containing heterocyclic compounds shown by the formula ##STR1## wherein one of R 1 and R 2 represents a lower alkyl group, a phenyl group, a halophenyl group, or a lower...
4268512 Substituted 2,3-alkylene bis (oxy) benzamides and derivatives and method of preparation  
Novel substituted 2,3-alkylene bis (oxy) benzamides and derivatives thereof are disclosed. Also disclosed is a method for producing said compounds. The compounds have anxiolytic, psychostimulant,...
4260612 Antiallergic nitrogen bridge-head compounds  
Antiallergic and antiasthmatic compounds of the formula ##STR1## of which 9-phenylamino-6-methyl-4-oxo-6,7-dihydro-4H-pyrido(1,2-a)pyr imidine-3-carb oxylic acid and optically active antipodes and...
4252807 Fused pyrimidine derivatives and antiatherosclerotic methods of treatment with them  
An optically active or racemic fused pyrimidine derivative of the formula I ##STR1## has pharmaceutical activity in decreasing serum lipids, cholesterol deposits and, in general, against...
4219649 Pyrido[1,2-a]pyrimidine derivatives  
Compounds of the formula: ##STR1## or pharmaceutically acceptable acid addition or quaternary ammonium salts thereof wherein R 2 is C 1 to C 6 alkyl: R 3 is C 1 to C 6 alkyl; R 4 is...
4214089 Thiazolo[3,2-a]benzimidazoles, imidazo [2,1-b]thiazoles, and related compounds as antineoplastic agents, and enhancers of the immune response  
The use of 3-aryl-thiazolo[3,2-a]benzimidazoles, 3-aryl-imidazo[2,1-b]thiazoles, and related compounds as antineoplastic agents, and/or as enhancers of the immune response is disclosed.
4209622 3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tet rahydro-4H-pyrido[1,2-a]pyrimidine  
Pyrida-(1,2A)-pyrimidine-derivatives and a process for preparing these compounds are disclosed. These compounds possess analgesic, anti-inflammatory, and anti-pyretic properties as well as the...
4192944 Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents  
A novel series of optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-5-yl)carbo xamides is provided for use as inhibitors of allergic reactions. The compounds exhibit...
Matches 101 - 150 out of 198 < 1 2 3 4 >