Patents in Class 544/245

Matches 1 - 50 out of 153

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Match	Document	Document Title
1	7612010	Use of metal complex compounds as oxidation catalysts Use of metal complex compounds of formula (1) and/or (1′) [L n Me m X p ] z Y q (1),
2	7595400	Process for the preparation of hexacyclic compounds This invention relates to novel processes for the preparation of compounds of the formula [1], wherein R1, R2, R3 and R4 are as defined in the claims and description as well as pharmaceutically...
3	7589200	5-Fluoro-4N-phenyl-4-pyrimidineamine compounds The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods...
4	7585856	Resolvins: Biotemplates for novel therapeutic interventions The present invention is generally drawn to novel isolated therapeutic agents, termed resolvins, generated from the interaction between a dietary omega-3 polyunsaturated fatty acid (PUFA) such as...
5	7537912	Methods of measuring luminogenic activity with a protected coelenterazine A method of measuring the enzymatic activity of a luciferase includes contacting a luminogenic protein, such as a luciferase, with a protected luminophore to form a composition; and detecting light...
6	7511125	Pyrimidine derivatives for labeled binding partners Compounds having structure (1) wherein R 1 is —H a protecting group, a linker or a binding partner; and R 2 and R 34 are as defined in the specification. The invention also provides...
7	7501427	Quinazoline analogs as receptor tyrosine kinase inhibitors This invention concerns quinazoline analogs of Formula I: where an A group is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is...
8	7456281	Nucleic acid melting analysis with saturation dyes Methods are provided for nucleic acid analysis wherein a target nucleic acid is mixed with a dsDNA binding dye to form a mixture. Optionally, an unlabeled probe is included in the mixture. A...
9	7427693	Polar liquid crystal Compounds that are useful in compositions for flat panel displays, for example, are provided. The compounds provided are polar, and are useful in low threshold voltage mixtures. The compounds...
10	7420056	Substituted bicyclic imidazo-3-ylamine compounds Substituted bicyclic imidazo-3-yl-amine compounds are provided, as well as processes for the production thereof and pharmaceutical formulations containing these compounds. The use of these...
11	7393367	Agent for dyeing keratin-based fibers An agent for dyeing keratin-containing fibers, especially human hair, is comprised of a cosmetic carrier, and (A) at least one compound of Formula I, wherein each of R 1 , R 2 ...
12	7390814	Substituted hexahydropyrazino [1,2-a] pyrimidine-4,7-dione derivatives, process for their preparation and their use as medicaments Substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives, processes for their preparation and their use as medicaments The invention relates to substituted...
13	7321033	3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof The invention is directed to 3-β-D-ribofuranosylthiazolo[4,5-d]pyridimine nucleosides and pharmaceutical compositions containing such compounds that have immunomodulatory activity. The invention...
14	7307168	Process for the preparation of 3-{2-′4- (6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyllethyl}-6,7,8,9-tetrahydro-2-methyl-4h-pyrido′1,2-methyl-4h-pyrido′,2-a!pyrimidin-4-one The invention relates to a process for the preparation of 3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl }-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-on e of the Formula...
15	7268229	Compounds to co-localize luminophores with luminescent proteins A method of measuring the enzymatic activity of a luciferase includes contacting a luminogenic protein, such as a luciferase, with a protected luminophore to form a composition; and detecting light...
16	7238771	Dibenzodiazocine polymers Dibenzodiazocine polymers, methods for producing dibenzodiazocine polymers, products formed from dibenzodiazocine polymers, and uses for such dibenzodiazocine polymers are provided.
17	7217717	Phenalene derivatives Novel 1,3,4-triaza-phenalene and 1,3,4,6-tetraazaphenalene derivatives are disclosed. These compounds inhibit epidermal growth factor receptor (“EGFR”) tyrosine kinase. These compounds and...
18	7176310	Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents This invention is directed to compound of the following formula (I): wherein R 1 , R 2 , R 3 and R 4 are as described herein. These compounds and pharmaceutical compositions containing the...
19	7160890	Compounds specific to adenosine A3 receptor and uses thereof This invention pertains to compounds which specifically inhibit the adenosine A 3 receptor and the use of these compounds to treat a disease associated with A 3 adenosine receptor in a subject,...
20	7138363	Use of metal complex compounds as oxidation catalysts Use of metal complex compounds of formula (1) and/or (1′) [LnMemXp]zYq (1), [L′MemXp]zYq (1′), wherein all substituents are as defined in the claims, as catalysts for oxidation reactions, and...
21	7119111	2-oxo-1,3,4-trihydroquinazolinyl derivatives and methods of use Selected compounds are effective for treatment of diseases, such as cell proliferation or apoptosis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and...
22	7109195	Hexacyclic compounds and their therapeutic use The present invention relates to hexacyclic compound of the formula [1], wherein Z, R 3 and R 4 are as identified therein, and pharmaceutically acceptable salts thereof. These compounds are...
23	7094783	Bicyclic pyrimidinones as coagulation cascade inhibitors The present invention relates generally to compounds that inhibit serine proteases. In particular it is directed to novel amino-bicyclic pyrimidinone compounds of Formula (I): or a stereoisomer...
24	7045624	Compounds and their uses Use of a compound according to Formula [I]: or a salt thereof to produce a cooling sensation, wherein R 1 and R 2 are independently selected from hydrogen or halogen atoms; hydroxy, cyano,...
25	6962991	Process for the synthesis of pyrazolopyrimidines The present invention provides a nucleoside comprising a pyrazolopyrimidine base and a process for producing the same. In particular, the processes of the present invention comprises using a...
26	6846335	Crystal form of a perinone dye A novel crystal form of C.I. Solvent Orange 60 gives a higher space-time yield in dye synthesis and is more easily finished.
27	6833455	Bridged perinones/quinophthalones Disclosed herein are bridged perinones/quinophthalones of the general formula (I) or tautomeric forms thereof where X1, X2, Ar 1 Ar 2 and B are as described herein and are particularly...
28	6831074	Pharmaceutically active compounds The present invention provides a compound of formula (I): where Q is a group of formula: These compounds inhibit cyclic guanosine 3′,5′-monophosphate phosphodiesterases (cGMP PDEs). More...
29	6825194	Hexacyclic compounds The present invention relates to hexacyclic compound of the formula [1], wherein Z, R 3 and R 4 are as identified therein, and pharmaceutically acceptable salts thereof. These compounds are...
30	6703504	Conformationally constrained compounds as dendrimer cores There are provided novel chemical compounds and their uses in the preparation of polymers and oligomers, and the preparation of such compounds. In certain embodiments there are provided dendritic...
31	6692562	Process for making perylene pigment compositions This invention relates to a process of preparing a perylene pigment compositions containing a reactive co-precipitated blend of (1) about 75 to about 99.9 mol %, relative to the pigment...
32	6683028	Cyclic guanidine derivatives and their use as pesticides The invention relates to novel guanidine derivatives of the formula (I) in which A, R 1 , R 2 , R 3 and Z are as defined in the description, to a process for their preparation and to their use...
33	6562968	Method of purifying tetrodotoxin The present invention relates to a new process of purifying tetrodotoxin using high performance liquid chromatograph technology.
34	6491847	Discotic liquid crystal and organic electroluminescence device using same A novel class of discotic liquid crystals represented by the following formula was synthesized, and a layer thereof was incorporated in an organic electroluminescence device.
35	6491749	Core-extended perylene bisimides The present inventions relates to nucleus-extended perylenebisimides of formula (I) intermediates in the preparation of compounds (I) and processes for the preparation of those intermediates and...
36	6380193	Fused tricyclic compounds, methods and compositions for inhibiting PARP activity A compound of formula I: or a pharmaceutically acceptable salt, hydrate, ester, solvate, prodrug, metabolite, stereoisomer, or mixtures thereof.
37	6281355	Nitrogen-containing tetracyclic compounds A nitrogen-containing tetracyclic compound represented by the formula: ##STR1## wherein Y 1 --Y 2 --Y 3 is N--CN or a group represented by the formula: CC--NR 3 (wherein R 3 is a...
38	6207671	Cycloalkano-pyridines The cycloalkano-pyridines are prepared by reacting corresponding cycloalkano-pyridine-aldehydes with suitable organometallic compounds or Wittig or Grignard reagents or reacting compounds of the...
39	6143748	Process for synthesis of nucleoside analogues The present invention is concerned with a process for the preparation of antiviral 1,3-oxathiolane nucleosides comprising an intramolecular glycosylation reaction to produce exclusively the...
40	6140270	Process for the preparation of 6-(perfluoroalkyl) uracil compounds from 2-(N,N-disubstituted) amino-4-(perfluoroalkyl)-1,3-oxazin-6-one compounds An improved process for the preparation of 6-(perfluoroalkyl)uracil compounds having the structural formula I ##STR1## from 2-(N,N-disubstituted)amino-4-(perfluoroalkyl)-1,3-oxazin-6-o ne compounds...
41	6107304	Thieno[2,3-b]pyrazolo[3,4-d]pyridine-3-ones to enhance erythropoiesis Invented are substituted thieno (2,3-b)pyrazolo(3,4-d)pyridin-3-ones, pharmaceutical compositions containing these compounds, and methods of using these compounds to enhance erythropoiesis. Also...
42	6093821	Process for preparing steroid receptor modulator compounds Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds,...
43	5958923	Use of thiazole and thiadiazole compounds The present invention relates to the use of thiazole and thiadiazole compounds of the following formula: ##STR1## where R 1 , A, B and Ar have the meanings stated in the description. The compounds...
44	5952335	Fused polycyclic heterocycle derivatives Novel fused polycyclic heterocycle derivatives having excellent antitumor effects and a process for producing the same. A compound represented by the following general formula (I) or...
45	5948903	Synthesis of 3-deazapurines This invention relates to compounds based on the 3-deazapurines ring system and to methods for making such compounds. The invention also generally relates to the field of "antisense" agents, agents...
46	5861398	Benzoperimidine-carboxylic acids and derivatives thereof Benzo(e)perimidine-4-carboxamide derivatives of general structural formula I ##STR1## (where R a , R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 are as defined in the specification) have activity for...
47	5830931	Process for the preparation of polycyclic compounds Process for the preparation of compounds of the general formula (I) ##STR1## by reaction of aromatic dicarboxylic acids of the formula (II) ##STR2## or anhydrides and/or esters thereof with...
48	5808060	Fused isoindolones Disclosed are biologically active, non-indole-containing compounds referred to as fused isoindolones, which are represented by the following general formula: ##STR1## The fused indolones can be...
49	5779934	Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same A fluorine-containing optically active compound represented by the formula (1): ##STR1## wherein R 1 is a saturated or unsaturated C 3 -C 20 alkyl group or a saturated or unsaturated C 3 -C 20 ...
50	5753663	Pyrimidine derivatives The disclosed pyrimidine derivatives, and pharmaceutically acceptable salts thereof, exhibit useful pharmacological properties, in particular use as 5HT 2C - antagonists. The invention is also...

Matches 1 - 50 out of 153

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