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9034655 Highly water-soluble, cationic luminescent labels  
Luminescent labels based on aromatic and heterocyclic compounds, including reactive intermediates used to synthesize these compounds, and methods of synthesizing and using these reporter...
9034485 Compounds for electronic devices  
The present invention relates to compounds of the formula (1) and to the use thereof in organic electronic devices, and to organic electronic devices which comprise compounds of the formula (1),...
8993595 Macrocyclic serine protease inhibitors  
Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof....
8940744 Pyrazolopyrimidine compounds as kinase inhibitors  
The present disclosure provides compounds of Formula (IA) and/or pharmaceutically acceptable salts thereof that are tyrosine kinase inhibitors, in particular BTK, and are potentially useful for...
8940412 Material for organic electroluminescent element, and organic electroluminescent element  
An organic electroluminescence device and a material for producing the organic electroluminescence device. The organic electroluminescence device includes an organic thin film layer between a...
8920944 Use of a precursor of an N-dopant for doping an organic semiconductive material, precursor and electronic or optoelectronic component  
Use of a precursor of an n-dopant for doping an organic semiconductive material, as a blocking layer, as a charge injection layer, as an electrode material, as a storage material or as a...
8895734 Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid  
The present invention provides a novel class of peptide nucleic acid derivatives, which show good cell penetration and strong binding affinity for nucleic acid.
8884008 Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid  
The present invention provides a novel class of peptide nucleic acid derivatives, which show good cell penetration and strong binding affinity for nucleic acid.
8859766 Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid  
The present invention provides a novel class of peptide nucleic acid derivatives, which show good cell penetration and strong binding affinity for nucleic acid.
8829014 Thiazole and thiophene analogues, and their use in treating autoimmune diseases and cancers  
Thiazole and thiophene compounds are disclosed having utility in treating inflammatory conditions, immunoinflammatory conditions, autoimmune diseases, and cancers. Methods for the synthesis of...
8815417 Heterocyclic compound and organic light-emitting device including the same  
A heterocyclic compound represented by Formula 1 below and an organic light-emitting device including the heterocyclic compound: wherein R1 to R12 are defined as in the specification.
8795691 Nanotubes and compositions thereof  
The present invention is directed to implants and the modification of the surface of implants using amino acid or polypeptide functionalized rosette nanotubes.
8691187 Imaging agents for detecting neurological disorders  
Imaging agents of formulas (I)-(V) and methods for detecting neurological disorders comprising administering to a patient in need compounds of formulas (I)-(V) capable of binding to tau proteins...
8669264 Rutaecarpine derivatives for activating CYP1A2 in a subject  
The teachings provided herein generally relate to compositions comprising rutaecarpine derivatives that activates CYP1A2 through enzyme induction. The uses for such a derivative can include...
8606529 High-resolution melting analysis  
The application relates to methods and systems for analysis of dissociation behavior of nucleic acids and identification of nucleic acids. In one aspect, methods and systems are disclosed for...
8604032 Chemical compounds, compositions and methods for kinase modulation  
Provided herein are compounds of formula (I), pharmaceutical compositions comprising the compounds, and methods of use thereof The compounds provided herein modulate kinase activity, including PI3...
8598148 Synthesis of tetracyclines and analogues thereof  
The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary...
8597801 Heterocyclic compound, organic light-emitting device including the heterocyclic compound, and flat display device including the organic light-emitting device  
A heterocyclic compound includes compounds represented by Formula 1 or Formula 2 below:
8551237 Synthesis of colorants in mixing apparatus  
A process for preparing colorants of the general formula (Ia), (Ib) or (Ic) or mixtures thereof, comprises reacting (a) tetracarboxylic acids or their functional derivatives with(b) at least one...
8541423 Methods and compositions for treating pain  
The present application relates to compounds and methods for treating pain, incontinence and other conditions.
8507500 Inhibiting neurotransmitter reuptake  
This document relates to compounds as well as methods and materials involved in modulating neurotransmitter reuptake. For example, compounds, methods for synthesizing compounds, and methods for...
8501749 Azaquinazolinediones chymase inhibitors  
Disclosed are small molecule inhibitors of the formula (I), which are useful in treating various diseases and conditions involving chymase.
8450482 Process for the preparation of 4-(3-chloro-2-fluoroanilino)-7-methoxy-6-([1-(N-methylcarbamoymethyl)piperidin-4-yl]oxy)quinazoline  
Processes for the preparation of 4-(3-chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbam oylmethyl)piperidin-4-yl]oxy}quinazoline, salts thereof, and the intermediates used in the process are...
8377962 Macrocyclic serine protease inhibitors  
Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof....
8247422 Use of condensed pyrimidine derivatives for the treatment of rheumatoid arthritis  
The invention relates to the use of a compound of the formula (I), or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for use in modulating an immune or...
8242122 Method and compounds for inhibition of cell death  
The invention is directed to methods and compositions for inhibiting caspase-independent apoptosis. In particular, methods and compositions for inhibiting Omi/HtrA2 activity, as well as method for...
8236950 Anti-viral compounds  
Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation...
8207172 Pyrimidinothienoindazoles useful for the treatment of hyperproliferative disorders  
The invention relates to novel heterocycles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of...
8193528 Azapyrenes for electronic applications  
The present invention relates to electronic devices, especially electroluminescent devices, comprising azapyrenes of formula (I), or formula (III), wherein Y1, Y2, Y3, Y4, X1, X2 and X3 are...
8180572 High-resolution melting analysis  
The present invention relates to methods and systems for the analysis of the dissociation behavior of nucleic acids and the identification of nucleic acids. In one aspect, methods and systems are...
8143255 Heteroalkyl linked pyrimidine derivatives  
The present invention relates to pyrimidine compounds that are useful as anti-proliferative agents. More particularly, the present invention relates to heteroalkyl linked and substituted...
8145433 High-resolution melting analysis  
The present invention relates to methods and systems for the analysis of the dissociation behavior of nucleic acids and the identification of nucleic acids. In one aspect, methods and systems are...
8076477 Adsorbents for protein purification  
Use of an affinity adsorbent for the separation, removal, isolation, purification, characterisation, identification or quantification of a proteinaceous material, wherein the affinity adsorbent is...
8053039 Polymerizable dichroic azo dyes  
The present invention is directed towards polymerizable dichroic azo dyes comprising azo-chromophores having at least one standard mesogenic ring system attached to said chromophores and at least...
7977378 Compositions and methods for enhancing weight-loss by cyclical administration of compounds  
Compositions and methods are provided for the treatment of obesity in a human in need of such treatment which comprises administration to the human of a therapeutically effective amount of a...
7956060 Pyrimidine derivative compound  
The present invention provides an antitumor agent and the like, which comprises as an active ingredient, a pyrimidine derivative represented by Formula (I): [wherein —X—Y—Z— represents —O—CR3═N—...
7943208 Materials and methods for the preparation of anisotropically-ordered solids  
The invention provides materials and methods for making anisotropic solids which may be in the form of films, layers, shaped elements, and other shaped articles. The methods provide anisotropic...
7910593 Water-soluble prodrugs  
An objective of the present invention is to provide water-soluble prodrugs that can be administered parenterally, and which show excellent water solubility and small interspecies or individual...
7851468 Substituted pyrazolo[3,4-d]pyrimidines  
The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that...
7799096 Agent for dyeing keratin-containing fibers  
The invention relates to an agent for dying fibers comprising keratin, particularly human hair, the agent comprising at least one compound of the formula: together with at least one CH-acidic...
7777032 Quinazoline analogs as receptor tyrosine kinase inhibitors  
This invention concerns quinazoline analogs of Formula I: where an A group is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted...
7772225 N-sulfamoyl-piperidineamides for the treatment or inhibition of obesity and related conditions  
The present invention relates to novel N-sulfamoyl-piperidineamides of Formula I and their physiologically acceptable acid addition salts, to pharmaceutical compositions comprising them, processes...
7750005 Substituted hexahydropyrazino [1,2-A] pyrimidine-4,7-dione derivatives, process for their preparation and their use as medicaments  
The invention relates to substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof....
7713981 Method and compounds for inhibition of cell death  
The invention is directed to methods and compositions for inhibiting caspase-independent apoptosis. In particular, methods and compositions for inhibiting Omi/HtrA2 activity, as well as method for...
7709448 Prodrugs of 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione  
The invention is directed to 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimi din-2,7-dione prodrugs, whose metabolized parent compound has immunomodulatory activity. The invention...
7662821 Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents  
The invention relates to tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents.
7652007 Nitrogen-substituted hexahydropyrazino[1,2-A]pyrimidine-4,7-dione derivatives, processes for their preparation and their use as medicaments  
Nitrogen-substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives, processes for the preparation and their use as medicaments The invention relates to substituted...
7635702 Imidazole compounds as transforming growth factor (TGF) inhibitors  
Novel imidazole compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The...
7595400 Process for the preparation of hexacyclic compounds  
This invention relates to novel processes for the preparation of compounds of the formula [1], wherein R1, R2, R3 and R4 are as defined in the claims and description as well as pharmaceutically...
7589200 5-Fluoro-4N-phenyl-4-pyrimidineamine compounds  
The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods...

Matches 1 - 50 out of 197 1 2 3 4 >