Patents in Class 544/184

Matches 1 - 50 out of 185

1 2 3 4 >

Match	Document	Document Title
1	7576084	Reverse-turn mimetics and method relating thereto Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetic structures...
2	7566711	Reverse-turn mimetics and method relating thereto Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetic structures...
3	7507734	Pyridazinone derivatives Disclosed are compounds according to the general formula (I), where the definitions of the substituents X, R 1 and R 2 are detailed in the description, as well as their physiologically acceptable...
4	7473669	Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones, and their use as fungicides This invention relates to substituted dihydrotriazinones, triazinones and related compounds, compositions comprising such compounds and an agronomically acceptable carrier, and the use thereof as...
5	7470689	4-benzimidazol-2-ylpyridazin-3-one derivatives Disclosed are compounds of the general formula (I), where the definition of the substituents A, B, D, E, R 1 and R 2 are detailed in the description, and the physiologically tolerated salts...
6	7462615	Inhibitors of cysteine proteases, the pharmaceutical compositions thereof and their therapeutic applications The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.
7	7462614	Imidazotriazine compounds The present invention provides compounds of formula (I): wherein all variables are as defined herein, pharmaceutical compositions containing the same, processes for preparing the same and their...
8	7419978	Phenyl-aniline substituted bicyclic compounds useful as kinase inhibitors Compounds having the formula (I), and pharmaceutically acceptable salts, prodrugs, and solvates thereof, are useful as kinase inhibitors, wherein R, R 1 , R 2 , R 5 , R 6a , R 6b , J, K, X and...
9	7326475	Material for organic electroluminescent device, organic electroluminescent device, illuminating device and display The present invention provides: an organic EL element exhibiting high luminance, a high external quantum efficiency and a long high temperature driving life at 50° C.; an illuminator and a display...
10	7317012	Bicyclic heterocycles as cannabinoind-1 receptor modulators The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional...
11	7253167	Tricyclic-heteroaryl compounds useful as kinase inhibitors The present invention relates to compounds having the formula, wherein, Q is optionally substituted aryl or heteroaryl, R 1 is hydrogen or C 1-4 alkyl, and R 2 , R 3 , R 4 and R 5 are...
12	7241763	3-furanyl analogs of toxoflavine as kinase inhibitors The present invention concerns the compounds of formula the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein m, n, R 1 , R...
13	7202243	Substituted imidazotriazines The invention relates to new substituted imidazotriazines, processes for their preparation and their use for the production of medicaments for the treatment and/or prophylaxis of cancer and...
14	7199121	Protein tyrosine phosphatase inhibitor Use of a compound of formula (I): wherein each R, which are the same or different, is H or C 1 –C 6 alkyl, and X completes a ring which is a substituted triazine having one of the following...
15	7196095	(Pyrimidinyl) (phenyl) substituted fused heteroaryl p38 inhibiting and PKG kinase inhibiting compounds Compounds of formula (I) and pharmaceutically acceptable salts thereof are useful in the treatment of cytokine mediated diseases such as arthritis and in the treatment and/or prevention of...
16	7176203	Imidazo-triazine derivatives as ligands for gaba receptors A class of imidazo[1,2 b ][1,2,4]triazine derivatives, substituted at the 7-position by an optionally substituted five-membered or six-membered heteroaromatic ring, being selective ligands for GABA...
17	7122548	Triazolotriazine compounds and uses thereof The present invention relates to compounds of the Formula (I), and their pharmaceutically acceptable salts. These compounds modulate the activity of c-Met and are therefore expected to be useful in...
18	7115602	Heterocycles 3 The invention relates to 7-(4-tert butyl-cyclohexyl)-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory...
19	7098207	Imidazotriazinones and the use thereof Novel imidazotriazinones of general formula a method for the production and the pharmaceutical use thereof are disclosed.
20	7087605	5-Ethyl-imidazotriazinones The invention relates to novel 5-Ethyl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or...
21	7074790	5-ethylimidarotriazones The invention relates to novel 5-ethyl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or...
22	7037910	Azabicyclic heterocycles as cannabinoid receptor modulators The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional...
23	7037909	Tetracyclic compounds as c-Met inhibitors The present invention relates to compounds of the Formulae (I) and (II), wherein R 1 -R 10 and G are defined herein, and their pharmaceutically acceptable salts. These compounds modulate the...
24	7022847	Method for the production of 2-(2-ethoxyphenyl)-substituted imidazotriazinones The invention relates to a method for the production of 2-phenyl-substituted imidazotriazinones of general formula (I), comprising the reaction of compounds of formula (II) with compounds of...
25	7005431	Imidazo-triazine derivatives as ligands for gaba receptors A class of 7-phenylimidazo[1,2-b][1,2,4]triazine derivatives, substituted at the meta position of the phenyl ring by an optionally substituted aryl or heteroaryl group which is directly attached or...
26	6998483	Process for the preparation of sulphonamide-substituted imidazotriazinones The present invention relates to a process for the preparation of sulphonamide-substituted imidazotriazinones of the general formula (I) characterized in that compounds of the formula (II) ...
27	6998402	Substituted imidazotriazinones The invention relates to novel substituted imidazotriazinones, to a method for their production and to the use thereof for producing medicaments, in particular to improve perception, powers of...
28	6984641	Carboline derivatives as PDE5 inhibitors Selective inhibitors of cGMP-specific PDE, and use of the compounds and salts and solvates thereof as therapeutic agents, are disclosed.
29	6977261	Azaisoquinoline derivatives as matrix metalloproteinase inhibitors This invention provides compounds defined by Formula I or a pharmaceutically acceptable salt thereof, wherein R 1 , Q, Y, R 2 , R 3 , R 4 , R 5 , and n are as defined in the specification....
30	6943163	7-Alkyl and cycloalkyl-substituted imidazotriazinones The present invention relates to 7-alkyl- and cycloalkyl-substituted imidazotriazinones, to processes for their preparation and to their use as medicaments, in particular as inhibitors of...
31	6943158	Diazinopyrimidines Compounds of formula I are p38 inhibitors: or a pharmaceutically acceptable salt thereof, wherein R 1 is hydrogen or alkyl; R 2 alkyl, haloalkyl, aryl, aralkyl, heteroaryl,...
32	6936609	Imidazotriazines for use as phosphodiesterase inhibitors The invention relates to new imidazotriazines, processes for their preparation, and their use for the production of medicaments for the treatment and/or prophylaxis of neurodegenerative disorders,...
33	6914060	Imidazotriazinone derivatives as ligands for GABA receptors The present invention relates to imidazo[2,1-f]triazin-4-one analogues which are substituted in the 7-position by a substituted phenyl ring, being ligands for GABA A receptors and accordingly of...
34	6890922	2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors The 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and...
35	6878708	Imidazotriazinones and the use thereof Novel imidazotriazinones of general formula (I), a method for the production and the pharmaceutical use thereof are disclosed.
36	6861427	Azabicyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-HT1A antagonists Compounds of the formula are useful for treating the cognitive deficits due to aging, stroke, head trauma, Alzheimer's disease or other neurodegenerative diseases, or schizophrenia, and are...
37	6818641	Arthropodicidal carboxanilides Compounds of Formula (I), and their N-oxides and agriculturally suitable salts, are disclosed which are useful as arthropodicides wherein A is H; E is H or C 1 -C 3 alkyl; or A and E can be taken...
38	6797710	Heterocyclic derivatives and their use as antithrombotic agents The present invention relates to antithrombotic compounds comprising the group Q, Q having formula (I), wherein the substructure (i) is a structure selected from (a, b and c), wherein X is O or S;...
39	6794387	Pharmaceutically active compounds Compounds of general formula (I): wherein R 1 , R 2 , R 3 , R 4 , X, Y and A have the meanings given herein which are useful in the curative and prophylactic treatment of a medical condition for...
40	6770645	Pharmaceutically active compounds Compound of general formula I: wherein R 1 , R 2 , R 3 , R 4 , X, Y and R 5 have the meanings given herein which are useful in the curative and prophylactic treatment of a medical condition for...
41	6740654	Squaric acid derivatives Squaric acid derivatives of formula (1) are described: wherein Het is an optionally substituted bicyclic fused ring heteroaromatic group; L 2 is a covalent bond or an atom or group —O—,...
42	6683081	Triazolotriazinones and the use thereof The invention relates to novel triazolotriazinones of the general formula (I), to a method for their production and to the pharmaceutical use thereof.
43	6664398	Derivatives of erythromycin, their preparation process and their use as medicaments A subject of the invention is the compounds of formula in which Y represents a hydrogen atom or a fluorine atom, n represents an integer comprised between 1 and 8, Z represents a hydrogen atom...
44	6642381	Pyrimido&lsqb 5,4-e&rsqb &lsqb 1,2,4&rsqb triazine-5,7-diamine compounds as protein tyrosine phosphatase inhibitors The invention relates to pyrimido[5,4-e][1,2,4]triazine-5,7-diamine compounds which are useful for inhibiting protein tyrosine phosphatases, particularly PTP1B.
45	6586429	Tricyclic fused xanthine compounds and their uses Novel tricyclic compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling....
46	6573263	Substituted imidazotriazinones The present invention relates to new substituted imidazotriazinones, processes for their preparation, and their use for the production of medicaments, in particular for improving perception,...
47	6541472	Compounds, compositions and methods for preventing and treating pestivirus infection and associated diseases Triazinoindole derivatives are useful in the prophylaxis and treatment of pestivirus infections and diseases associated with pestivirus infections.
48	6541469	CRF receptor antagonists and methods relating thereto CRF receptor antagonists are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded...
49	6525056	Heterocyclyl-substituted ring-fused pyridines and pyrimidines as corticotropin releasing hormone (CRH) antagonists, useful for treating cns and stress-related disorders Corticotropin releasing factor (CRF) antagonists of Formula (I): and their use in treating psychiatric disorders and neurological diseases, anxiety-related disorders, post-traumatic stress...
50	6525000	Method for producing anellated triazoles and new anellated triazoles and their use A process for preparing fused triazoles of formula I where: X—X is C—O, C—S, C—SO, C—SO 2 , or C—NR 1 ; V is C═W 2 , R 1 R 2 C—C(═W 2 )— or C(═V 2 )—C(═W 2 ); W 1 , W 2...

Matches 1 - 50 out of 185

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