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7622432 |
Lubricant composition and triazine-ring-containing compound
A novel lubricant composition is disclosed. The composition comprises the compound selected from the formula (1), where D represents an m-valent cyclic group capable of bonding to “m” of...
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7598246 |
Bisphosphonate conjugates and methods of making and using the same
The present invention provides novel bisphosphonate conjugates, pharmaceutical compositions comprising bisphosphonate conjugates and methods of using such analogs in the treatment of bone cancer,...
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7595343 |
Inhibitors of histone deacetylase
The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides...
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7585333 |
Triazinylaminostilbene disulphonic acid mixtures
The present invention relates to a fluorescent whitening agent comprising a mixture of two symmetrically and one asymmetrically substituted triazinylaminostilbene disulphonic acids, certain novel...
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7579465 |
Antiviral agents
This invention relates to compounds of formula I
their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the...
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7566710 |
Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof
The invention relates to dual molecules formed from coupling products complying with the formula
wherein A represents a residue of molecule with anti-malarial activity, Y 1 and Y 2 ,...
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7556910 |
Photosensitive composition comprising triazine-based photoactive compound containing oxime ester
The present invention relates to a photosensitive composition comprising a triazine-based photoactive compound containing oxime ester. The photosensitive composition according to the present...
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7504501 |
Antiprotozoal imidazopyridine compounds
Compounds described by the Formula (I): (I) or pharmaceutically acceptable salts, or N-oxides thereof. The compounds are useful for the treatment and prevention of protozoal diseases in mammals and...
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7473732 |
High-gloss room temperature curable water-based mold release agent
A room temperature curable water-based semi-permanent mold release agent is provided that is effective to facilitate the release of multiple successively molded polymer (such as polyester) parts...
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7462404 |
Electroluminescent boron complexes
Novel boron complexes are blue emissive electroluminescent compounds.
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7456276 |
Peptide purification by means of metal ion affinity chromatography
A polymer substrate functionalized with a functionality comprising at least one cyclic, metal ion coordinating ligand group, the cyclic ligand group comprising at least 3 metal ion coordinating...
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7455917 |
Organic compound and organic light emitting device using the same
Disclosed is a compound represented by formula 1:
[formula 1]
wherein each of A, X, Y, Y′ and Y″ has the same meaning as described herein. When used in an organic light emitting device,...
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7449574 |
Triazine based photoactive compound containing oxime ester
The present invention relates to a triazine based photoactive compound containing an oxime ester group. The compound according to the present invention is a photoactive compound containing both an...
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7442792 |
Process for the preparation of pyrazolo[1,5-a]-1,3,5-triazines and intermediates thereof
The present invention provides novel processes and intermediates for preparing corticotropin releasing factor (CRF) receptor antagonists having the structure below which are useful in treating...
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7429590 |
Antiprotozoal imidazopyridine compounds
Compounds described by the Formula (I) or (II): or pharmaceutically acceptable salts, or N-oxides thereof. The compounds are useful for the treatment and prevention of protozoal diseases in mammals...
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7414011 |
Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators
Disclosed are compounds of the formula (I) or salts thereof
in which R 1 , R 2 , R 3 , R 4 , I, R 5 , Q, R 4 , W, X, Y, V and Z, are as defined in the specification, which are suitable for use...
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7407976 |
Thiazoles and oxazoles useful as modulators of ATP-Binding Cassette transporters
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator (“CFTR”), compositions...
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7407962 |
Heteroaryl compounds useful as inhibitors or protein kinases
The present invention provides compounds that are inhibitors of protein kinase, particularly inhibitors of ERK2, GSK3, PKA, CDK2 protein kinases, mammalian protein kinases involved in proliferative...
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7405296 |
Additives for fluorinated oils
Compounds of formula
wherein
R f is a (per)fluoropolyoxyalkylene chain having a number average molecular weight in the range 500-10,000; W 1 , W 2 , equal to or different from each...
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7405217 |
N-aroyl piperazine derivatives as orexin receptor antagonists
This invention relates to N-aroyl cyclic amino derivatives and their use as pharmaceuticals.
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7358244 |
Azabicycloalkane compounds
This invention provides compounds of formula I:
wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 are as defined in the specification, or a pharmaceutically acceptable salt or solvate or...
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7348335 |
Compositions useful as inhibitors of JAK and other protein kinases
The present invention provides a compound of formula I:
or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising the...
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7329757 |
Substituted iminoazines
The invention relates to novel substituted iminoazines of the general formula (I)
in which
R 1 , R 2 , R 3 , R 4 , Z 1 , Z 2 and Z 3 are each as defined in the disclosure, to a plurality of...
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7326706 |
Pyrazine modulators of cannabinoid receptors
The present application describes compounds according to Formula I, wherein A, G 1 , G 2 and R 1 are described herein. Additionally, the present application describes pharmaceutical compositions...
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7312227 |
Compositions useful as inhibitors of JAK and other protein kinases
The present invention provides a compound of formula I:
or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising the...
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7261743 |
Dicationic compounds for dyeing human keratin fibers, and compositions comprising them
The present disclosure relates to the process of dyeing human keratinous fibers, such as the hair, with at least one specific direct dye in cosmetic compositions. Also disclosed herein are the...
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7259163 |
4-(6-membered)-heteroaryl acyl pyrrolidine derivatives as HCV inhibitors
Novel anti-viral agents of Formula
wherein:
A represents OR 1 , NR 1 R 2 , or R 1 wherein R 1 and R 2 are hydrogen, C 1-6 alkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl; or R 1 and...
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7256287 |
Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
The present invention is directed to small molecule inhibitors of the IgE response to allergens, which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic....
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7235560 |
Pyrimidine derivative as selective COX-2 inhibitors
The invention provides the compounds of formula (I)
or a pharmaceutically acceptable salt thereof.
Compounds of formula (I) are potent and selective inhibitors of COX-2 and are of use in the...
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7232467 |
Method of coloring porous material
A method of colouring porous material, especially human hair, is described, which method comprises applying to the material being coloured, in any desired order successively, or simultaneously, a)...
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7229479 |
Method of coloring porous material
A method of coloring porous material, especially human hair, is described, which method comprises applying to the material being colored, in any desired order successively, or simultaneously, a) at...
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7230139 |
Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents
The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic...
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7226927 |
Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators of caspases and inducers of apoptosis and the use thereof
The present invention is directed to substituted 2-aryl-4-arylaminopyrimidine and analogs thereof, represented by the general Formula I:
wherein A, Ar 1 , Ar 2 , R 1 and R 3 are defined...
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7217844 |
Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents
The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic...
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7211665 |
Sulfide scavenger
1,3,5-(2H 2 ,4H 2 ,6H 2 ) tripropanediamine N,N,N′,N′,N″,N″ hexamethyl is used to scavenge sulfur compounds from hydrocarbons. A novel method of making the triazine comprises autocondensing...
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7208596 |
Processes for the preparation of pyrazolo[1,5-a]-1,3,5-triazines and intermediates thereof
The present invention provides novel processes and intermediates for preparing corticotropin releasing factor (CRF) receptor antagonists having the structure below which are useful in treating...
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7205302 |
Heterocyclic compound derivatives and medicines
The present invention provides a compound which is useful as a PGI 2 receptor agonist, and a pharmaceutical composition. The present invention is directed to a pharmaceutical composition...
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7198958 |
Method for increasing hydrophilicity of fluorescent label compounds
A fluorescent label compound of formula
where Z is a reactive group that can be used for covalent coupling of the fluorescent label compound to other molecule. Either the fluorophore is a...
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7189266 |
Dyeing composition for human keratinous fibres with direct dyes and dicationic compounds
The present disclosure relates to a composition for dyeing human keratin fibers, such as the hair, comprising, in a medium suitable for dyeing, at least one direct dye and at least on dicationic...
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7186834 |
Substituted iminoazines
The invention relates to novel substituted iminoazines of the general formula (I)
in which R 1 , R 2 , R 3 , R 4 , Z 1 , Z 2 and Z 3 are each as defined in the disclosure,
to a...
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7186843 |
Aminomethylpyrrolidine derivatives having aromatic substituents
This invention provides a quinolone derivative having potent antibacterial activity against various bacteria including drug-resistant strains which is a compound of the following formula wherein R...
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7172631 |
Dyeing composition for human keratinous fibers with oxidation dyes and dicationic compounds
The present disclosure relates to a dyeing composition for human keratinous fibers, such as the hair, comprising, in a suitable dyeing medium, at least one oxidation dye, and at least one...
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7169949 |
Silane-modified UV absorbers and coatings
Including a triazine UV light absorber having a silane group in a coating improves scratch and mar resistance after weathering.
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7141688 |
Fluorinated dye stabilizers in fluorinated dielectric solvent
The present invention is directed to novel fluorinated dye stabilizers having both high quenching efficiency and solubility in halogenated solvents. These dye stabilizers have shown a significantly...
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7138414 |
Heterocyclically substituted benzoylureas, process for their preparation and their use as pharmaceuticals
The invention relates to heterocyclically substituted benzoylureas and also to their physiologically tolerated salts and physiologically functional derivatives. Compounds are described of the...
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7122544 |
Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto
Compounds having activity as inhibitors of IKK are disclosed, particularly IKK-2. The compounds of this invention are anilinopyrimidine derivatives having the following structure:
wherein R 1 ...
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7105661 |
Process for manufacturing morpholino-nucleotides, and use thereof for the analysis of and labelling of nucleic acid sequences
The invention relates to the use of morpholino-nucleosides of formula:
in which R 1 represents a nucleic base and R 2 represents a group corresponding to one of the following formulae:
...
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7081526 |
Process for manufacturing morpholino-nucleotides, and use thereof for the analysis of and labelling of nucleic acid sequences
The invention relates to the use of morpholino-nucleosides of formula:
in which R 1 represents a nucleic base and R 2 represents a group corresponding to one of the following formulae:
...
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7077872 |
Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives
The object of the present patent application are agents for dyeing keratin fibers based on a developer-coupler combination and characterized in that they contain at least one 3-aminophenol...
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7078403 |
Antiviral agents
Disclosed herein are compounds of formula II:
wherein Alk, Z, X 1 , X 2 , R 1 , —R 10 and R 11 are defined herein, and their salts and pharmaceutically acceptable derivatives thereof, as...
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