Patents in Class 544/128

Matches 151 - 200 out of 505

Match	Document	Document Title
151	5770734	N-substituted-2-aminoquinolines useful for treating hypofunction of the cholinergic system
152	5756422	Substituted quinoline compounds and their use as safeners Substituted quinoline compounds, processes for their preparation, composition containing them, and their use as safenersCompounds of the formula I and salts thereof ##STR1## in which R1 lacuna! CN,...
153	5753673	Quinolinecarboxylic acid derivatives Quinolinecarboxylic acid derivatives represented by the following formula: ##STR1## wherein C is hydroxymethyl, methoxy, ethoxy or morpholinyl, or pharmaceutically acceptable salts thereof exhibit...
154	5744607	Basic derivatives of glutamic acid and aspartic acid as gastrin or cholecystokinin antagonists The invention is directed to glutamic acid and aspartic acid derivatives represented by formula (I): ##STR1## wherein R1 is selected from the group consisting of unsubstituted, mono- or...
155	5714497	Compounds bearing sulphamoyl and amidino radicals, their preparation process and pharmaceutical compositions containing them The subject of the invention is the compounds of formula I ##STR1## in which Ar1 represents naphtyl, phenyl, quinolyl or isoquinolyl optionally substituted; Ar2 represents a phenyl or thienyl...
156	5708173	Heterocyclic compounds A compound of the formula: ##STR1## or its salt is prepared by reacting a compound of the formula: ##STR2## with a compound of the formula: ##STR3## Wherein the variables are all defined in claim 1.
157	5691356	Disubstituted heterocyclic thrombin inhibitors Disubstituted heterocyclic thrombin inhibitors are provided which have the structure ##STR1## wherein G is ##STR2## wherein n is 0, 1 or 2 or 3; m is 0, 1, 2 or 3; Y is NH or S; p is 0, 1 or 2, Q...
158	5672600	Antimicrobial dithiocarbamoyl quinolones Antimicrobial dithiocarbamoyl quinolone compounds of the general formula: ##STR1## wherein (1) A1, A2, A3, R1, R3, R4, and R6 form any of a variety of quinolone and related heterocyclic structures...
159	5658926	Carbostyril derivative and platelets aggregation inhibitory agent The present invention provides a carbostyril derivative represented by the following general formula ##STR1## (wherein A, R and W have the same definitions as given above; and the carbon-to-carbon...
160	5654298	Amine derivatives This invention concerns novel aminopyridinium compounds of the formula I wherein R1, R2, R3, R5 and R6 are selected from the following combinations: ##STR1## (a) one of R2 and R6 is a basic group...
161	5654296	Condensed heterocyclic compounds, their production and use The compound ##STR1## wherein ring A represents a benzene ring; Ar represents an aromatic group; R1 and R2 independently represent hydrogen, acyl or hydrocarbon group or R1 and R2 taken together...
162	5654316	Piperidine derivatives as neurokinin antagonists The invention relates to compounds of the formula ##STR1## wherein X, i, j, n, n', A, A', R2, R3, and U are as described herein. The compounds of the invention are NK1 or NK2 or NK3 receptor...
163	5652247	Carbostyril derivatives Novel carbostyril derivatives of the formula: ##STR1## wherein R1 is H, NO2, alkoxy, alkoxycarbonyl, alkyl, halogen, optionally substituted amino, OH, CN, COOH, alkanoyloxy, hydrazinocarbonyl; q is...
164	5614518	Morpholine derivatives as dopamine receptor subtype ligands A class of substituted morpholine derivatives of formula ##STR1## wherein Y represents an optionally substituted bicyclic heteroaromatic ring system containing one or two nitrogen atoms, the ring...
165	5607943	Annelated dihydropyridines and the use thereof for preparing pharmaceutical preparations A compound of formula I ##STR1## wherein A denotes a benzo, indolo or thieno group; R1 denotes thienyl or the group ##STR2## wherein R7, R8 and R9 independently of one another may represent methyl,...
166	5593991	Imidazole compounds, use and process of making Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
167	5591744	Benzoheterocyclic compounds Novel 4-oxoquinoline-3-carboxylic acid compounds of the formula: ##STR1## wherein R1 is cyclopropyl which may have 1 to 3 substituents of alkyl and halogen; phenyl which may be substituted by 1 to...
168	5578604	5-vinyl- and 5-ethinyl-quinolone- carboxylic acids The invention relates to new 5-vinyl- and 5-ethinyl-quinolone- and -naphthyridonecarboxylic acids, to processes for their preparation, and to antibacterial compositions and feed additives...
169	5574034	Pyrrolyl naphthopyrans The invention provides pharmaceutical compounds of the formula: ##STR1## in which A - - - B is CH2 --CH2 or CHCH; X is a pyridine or benzene ring; when X is pyridine n is 0; when x is benzene n i...
170	5565571	Substituted aryl- and heteroaryl-phenyloxazolidinones The present invention discloses novel substituted aryl- and heteroarylphenyloxazolidinones which are useful as anti-bacterial agents. More specifically, the substituted aryl- and...
171	5561146	Modified guanidino and amidino thrombin inhibitors Thrombin inhibitors are provided which have the formula ##STR1## wherein Z is a thrombin inhibitor substructure containing distal and proximal binding site residues; and R1 is cyano, hydroxyl,...
172	5559125	Hydroxyquinolone derivatives A class of 4-hydroxy-2-(1H)-quinolone derivatives, substituted at the 3-position by an optionally substituted aryl substituent, are selective non-competitive antagonists of NMDA receptors and/or...
173	5541325	Intermediates for the preparation of 1,3,dihydro-2H-imidazo[4,5-B]quinolin-2-one derivatives The present invention relates to compounds of the formula ##STR1## wherein R represents hydrogen; C1-6 alkyl; C3-6 cycloalkyl; phenyl optionally substituted with from 1 to 3 substituents each...
174	5527811	Isoquinolinyl compounds which are useful in treating cerebral vascular disorders Compounds represented by the formula: ##STR1## wherein the ring A and the ring B each stand for an optionally substituted benzene ring; Ar stands for an optionally substituted aryl group or an...
175	5516784	Anti-HIV (AIDS) agents Compounds of formula ##STR1## wherein Ar, W, Z, Q, R1, U, and T are as set forth herein, are described. These compounds are active as agents against retroviruses and in particular against HIV.
176	5506227	Pyridine-substituted benzyl alcohols as leukotriene antagonists Compounds having the formula I: ##STR1## are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents....
177	5482961	Soft β-adrenergic blocking agents New soft β-adrenergic blocking agents, useful in the treatment or prevention of cardiovascular disorders and in the treatment of glaucoma, have the formula ##STR1## wherein n is an integer from 0 ...
178	5468742	8-vinyl- and 9-ethinyl-quinolone-carboxylic acids The invention relates to new 8-vinyl- and 8-ethinylquinolonecarboxylic acids, process for their preparation, and antibacterial agents and feed additives containing them.
179	5457104	Quinolone- and naphthyridonecarboxylic acid derivatives The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which have hydrogen in the 6-position, to processes for their preparation, and to antibacterial compositions and...
180	5428033	Saturated hydroxyalkylquinoline acids as leukotriene antagonists Compounds having the formula I: ##STR1## are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and...
181	5416094	Antiarrhythmic and cardioprotective substituted -1(2H)isoquinolines, medicament containing them, and their use for combating heart failures Described are guanidinocarbonyl isoquinolines of the formula I, ##STR1## wherein R(1) is hydrogen, (amino) (cyclo) (aryl)alk(en)yl (heteroaryl); R(2) is hydrogen, halogen, alkyl, or aryl; G is a...
182	5407932	Quinolone derivatives and antibacterial agents containing the same Antibacterial quinolone derivatives represented by the following formula [I] and salts thereof are disclosed. ##STR1## wherein R1 means a hydrogen atom or a carboxyl-protecting group; R2 denotes a...
183	5405845	(Pyrrolidinyl)phenyl carbamate derivatives and use Novel (pyrrolidinyl)phenyl carbamates and related compounds, intermediates and processes for the preparation thereof, and methods of relieving memory dysfunction utilizing the carbamates and...
184	5401740	Carbostyril derivative The novel carbostyril derivative represented by the general formula (1) ##STR1## [in the formula, A, R1, R2 and the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton have...
185	5391748	Dihydroquinolines The present invention relates to dihydroquinolines of formula (I): ##STR1## in which the symbols used are as defined in the description, to a process for their preparation, to their use in...
186	5387686	Dye for heat-sensitive transfer record and ink composition for heat-sensitive transfer record A dyestuff for heat-sensitive transfer record is here disclosed which can be represented by the formula (1) ##STR1## wherein R1 is a hydrogen atom, alkyl group having 1 to 8 carbon atoms or...
187	5374724	Process for the preparation of substituted acetic acids A process for the preparation of a substituted acetic acid of the Formula (2): ##STR1## wherein --X--Z is an optionally substituted aromatic or heteroaromatic optionally substituted amino radical;...
188	5354749	Sulfonylbenzyl-substituted benzo- and pyridopyridones Sulfonylbenzyl-substituted benzo- and pyridopyridones are prepared by reacting corresponding benzo- and pyridopyridones with sulphonylbenzyl compounds. The sulphonylbenzyl-substituted benzo- and...
189	RE34722	Quinoline amino acid derivatives of carbostyril compounds Disclosed are carbostyril derivatives and their salts of the formulas ##STR1## The compounds have anti-peptic ulcer effects, and are useful as a treating agent for curing peptic ulcers in the...
190	5338739	(Pyrrolidinyl)phenyl carbamates, compositions and use Novel (pyrrolidinyl)phenyl carbamates and related compounds, intermediates and processes for the preparation thereof, and methods of relieving memory dysfunction utilizing the carbamates and...
191	5310744	Quinolylmethoxyphenyl-acetamides Quinolylmethoxyphenyl-acetamides of the formula: ##STR1## in which A, B, D, E, G, L and M are hydrogen, hydroxyl, halogen, cyano, carboxyl, nitro, trifluoromethyl, trifluoromethoxy, alkyl, alkoxy...
192	5304554	4-[(alkyl or dialkyl)amino]quinolines and their method of preparation Novel 4-[(alkyl or dialkyl)amino]quinolines are disclosed that are prepared by condensin BACKGROUND OF THE INVENTION The United States government has rights in this invention as a result of a grant...
193	5300513	Carbostyril derivatives and pharmaceutical composition containing the same Novel carbostyril derivatives of the formula: ##STR1## wherein X is 0 or S; Y is H or alkyl; RA is a group of the ##STR2## {wherein n is 1 or 2, A is alkylene, R1 is benzoyl having optionally 1-3...
194	5300643	Quinolonecarboxylic acid derivatives New quinolone-carboxylic acids of the general formula (I) ##STR1## wherein the definitions for R1 -R9 are given in the description, a process for their preparation and their use as medicaments, in...
195	5270309	Kynurenic acid derivatives useful in the treatment of neurodegenerative disorders 4-Oxo-1,4-dihydroquinoline compounds having a 2-acidic group or a group convertible thereto in vivo, and their pharmaceutically acceptable salts, are potent specific antagonists of...
196	5268378	Dioxo-tetrahydroquinoline derivatives A class of 2,4-dioxo-1,2,3,4-tetrahydroquinoline derivatives, substituted at the 3-position by a range of carbonyl-containing substituents or by a five- or six-membered heteroaromatic moiety, are...
197	5266568	Hydroxyalkylquinoline ether acids as leukotriene antagonists Compounds having the formula I: ##STR1## are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and...
198	5254566	Decahydroquinoline compounds A compound selected from the group consisting of racemates, enantiomeric and diastereoisomeric forms of a compound of the formula ##STR1## wherein R1 and R2 are individually selected from the group...
199	5252735	Antiatherosclerotic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones This invention relates to compounds of Formula I ##STR1## which are useful as antiatherosclerotic agents and inhibitors of cell proliferation for the treatment of proliferative diseases. In...
200	5225413	pH-neutral aqueous solutions of quinolone-carboxylic acids A pH-neutral aqueous solution of a quinolonecarboxylic acid of the formula ##STR1## in which R1 represents halogen, C1-4 -alkyl or C2-4 -alkenyl, R2 and R3 represent hydrogen, C1-4 -alkyl, or...

Matches 151 - 200 out of 505

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