Matches 151 - 200 out of 235 < 1 2 3 4 5 >
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4766212 2H-[1]benzoxepino[5,4-b]-1,4-oxazine derivatives  
Derivatives of 2H-[1]benzoxepino[5,4-b]-1,4-oxazine, such as trans-3,4,4a,5,6,11b-hexahydro-10-methoxy-2H-[1]benzoxepino[ 5,4-b]-1,4-oxa zine, are prepared by acylating a...
4762831 Antibacterial 1,8-bridged 4-quinolone-3-carboxylic acids  
A process for the preparation of a 1,8-bridged 4-quinolone-3-carboxylic acid of the formula ##STR1## wherein the substituents are defined hereinbelow. Some of the compound are new. The old and new...
4761413 1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins and use in treatment of ulcers  
The synthesis of epoxybenzazepin compounds is described. The novel compounds have anti-ulcer activity.
4758661 Chiral synthesis of (+)-trans-1a,2,3,4a,5,6-hexahydro-9-hydroxy-4-propyl-4H-naphth[1,2-b]-1, 4-oxazine  
(+)-trans-1a,2,3,4a,5,6-Hexahydro-9-hydroxy-4-propyl-4H-naph th[1,2-b]-1,4-o xazine is elaborated by a series of process steps that retain the enantiomeric purity of the starting material,...
4753953 Pyridonecarboxylic acid derivatives and antibacterial pharmaceutical compositions thereof  
Pyridonecarboxylic acid derivatives of the following formula, ##STR1## wherein R is hydrogen atom or lower alkyl group, R 1 is lower alkyl group, cycloalkyl group or haloalkyl group, Y is hydrogen...
4743601 Dihydro-1,4-oxazino(2,3-C)quinolines  
There are disclosed novel compounds of the formula ##STR1## where X is hydrogen, loweralkyl, loweralkoxy, hydroxy, halogen, nitro or trifluoromethyl; R 1 is hydrogen or loweralkyl; R 2 is...
4737466 N-acyldihydroresorufin derivatives, processes for their preparation, reagents containing them and the use thereof for determining hydrogen peroxide, peroxidate-acting compounds or peroxidase  
The present invention provides N-acylidihydroresorufin derivatives of the general formula: ##STR1## wherein R 1 is a lower alkyl, aryl or aralkyl radical, which can be substituted by carboxyl or...
4710570 Azine redox dyes and leuco azine dyes  
Azine redox dyes and their corresponding dyes of the formula: ##STR1## in which: X is O, S, NR 2 , Z completes a fused aromatic of heterocyclic ring system, n is 0 or 1 to allow one R 1 ring...
4695633 Chromogenic 4,4-diaryl-dihydroquinazolones, their preparation and their use  
Chromogenic 4,4-diaryl-dihydroquinazolones of the formula ##STR1## wherein X 1 , X 2 and X 3 independently of one another represent hydrogen, halogen, alkyl, aryl, alkanoylamino, aroylamino, NY 1...
4668671 Tricyclic derivatives and pharmaceutical use  
This invention describes tricyclic derivatives which are useful as histamine H 1 -antagonists. A particular compound of this invention is...
4661482 Use of pyrazolobenzoxazines in method of treating cerebral senescence and cerebral hypoxin  
Novel pyrazolobenzoxazines of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, cycloalkylalkyl or 4 to 7 carbon atoms, alkenyl and...
4656167 Naphthoxazines and their use as psychostimulating and antidepressant agents  
3,4,4a,5,10,10a-hexahydro-2H-naphth[2,3-b]-1,4-oxazines are useful as psychostimulating and antidepressant agents.
4634766 1,4-diaza-phenothiazines  
Compounds of the Formula I: ##STR1## are inhibitors of the mammalian 5-lipoxygenase enzyme system of the arachidonic acid cascade. As such, these compounds are useful therapeutic agents for...
4623650 Antibiotic derivatives of 7-phenyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids  
1-Substituted-6-fluoro-7-aryl-(8-fluoro)-1,4-dihydroquinol-4 -one 3-carboxylic acids having antibacterial activity are prepared by reacting the corresponding alkyl...
4571396 Antibacterial agents  
Novel naphthyridine-, quinoline- and benzoxazine-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial...
4552956 Partially hydrogenated pyrazolo, pyrimido and thiazolo[1,4]benzoxazines  
Pyrazolo, pyrimido and thiazolo[1,4]benzoxazines, useful as dopamine agonists.
4552874 Pyrazolooxazines, pyrazolothiazines, and pryazoloquinolines and their use as medicaments  
The invention relates to pyrazolooxazines, pyrazolothiazines and pyrazoloquinolines defined herein by Formula I. The invention also includes compositions containing said Formula I compounds and...
4547499 2,4-Dihydr o-2(omega-aminoalkyl)-1H-[1,2,4]triazolo[3,4-c]benzoxazin-1-one anti-alle rgy drug compounds, compositions and use  
2,4-Dihydro-2-(omega-aminoalkyl)-1H-[1,2,4]triazolo[3,4-c][1 ,4]benzoxazin-1 -ones of the formula ##STR1## where n and -NRR are as defined in the specification, e.g.,...
4540691 Dopamine agonists and use thereof  
Compounds are disclosed having the formula: ##STR1## wherein: R 1 is H, OH, --OCH 3 , --CH 2 OH, --NH 2 , --NHMe, --NHEt, --NMe 2 , --NEt 2 , ##STR2## R 2 is H, --CH 3 , or ##STR3## R 3 is...
4539401 Pyridobenzoxazine derivatives useful as antibacterial agents  
Pyridobenzoxazine derivatives of formula (I) ##STR1## wherein: X 1 represents a hydrogen atom or a halogen atom, R 1 represents a cyclic amino group which may contain additional hetero atom(s)...
4537888 Substituted benzoxazine derivatives and fungicidal use  
Novel Substituted benzoxazine derivatives of the formula ##STR1## in which X is oxygen or suophur, and R 1 and R 2 each independently is hydrogen, alkyl, alkoxy, akylthio, halogenoalkyl,...
4492697 4H-Imidazo[2,3-c]pyrido[2,3-e][1,4]oxazine derivatives  
The invention discloses novel 4H-imidazo[2,3-c]pyrido[2,3-e][1,4]oxazine derivatives, processes for their preparation, pharmaceutical compositions thereof and methods for using the compounds. The...
4476125 Benzobisoxazinetetrones and anti-allergic use thereof  
New benzobisoxazinetetrones having anti-allergic activity are described. These benzobisoxazinetetrones are represented by the following formula: ##STR1## and pharmaceutically acceptable salts...
4474784 Substituted imidazo 1,2-a-quinoxaline-4-(5H)ones, their compositions and method of use  
Novel compounds of the formula ##STR1## wherein A is selected from the group consisting of nitrogen and CH--, G is selected from the group consisting of --0--, ##STR2## Z is selected from the...
4473568 Antibacterial thiazolidine or thiomorpholine substituted quinolines  
Certain thiazolidine or thiomorpholine substituted quinoline and pyridobenzoxazine compounds are antibacterial agents. Method for their preparation and use are disclosed.
4443610 Bicyclothiazoles  
Bicyclothiazoles having the structure: ##STR1## wherein n is 3, 4, or 5 R 1 is hydrogen or alkyl, R 2 is hydrogen, alkyl, hydroxyl, alkoxy, cyano, phenyl, carboxyl, tetrazole, or halogen, ...
4443447 Phenyl-substituted tricyclic antibacterial agents  
Antimicrobial compounds of the following formula are disclosed: ##STR1## wherein X is selected from the group consisting of --O--, --CH 2 and ##STR2## m is 0 or 1; R 1 is selected from the group...
4431647 Method of use of enantiomers of trans-indeno[1,2-b]-1,4-oxazines  
The (R,R)-enantiomers of trans-indeno[1,2-b]-1,4-oxazines demonstrate dopaminergic activity, whereas the (S,S)-enantiomers demonstrate α-adrenergic antagonist activity. They are prepared by...
4420480 Hexahydronaphth[1,2-b]-1,4-oxazines  
Hexahydronaphth[1,2-b]-1,4-oxazines have dopaminergic activity and display α 2 -adrenergic receptor antagonism. They are useful in the treatment of parkinsonism, depression and hypertension. An...
4385175 Esters of retinoic acid and azetidinone derivatives  
There are disclosed esters of retinoic acid and alcohols which are azetidinone derivatives. These esters are useful as anti-cancer agents.
4382892 Benzoxazine derivatives  
Pyrido[1,2,3-de][1,4]benzoxazine derivatives are described having the formula (I) ##STR1## wherein X is a halogen atom, R is a hydrogen atom or an alkyl group of 1 to 6 carbon atoms and Z...
4366314 Dimethine dyestuffs, their preparation and their use for dyeing synthetic and natural materials  
Styryl dyestuffs of the general formula ##STR1## wherein Het represents a pyridinium radical having the structure ##STR2## R and R 1 independently of one another designate lower alkyl or alkenyl...
4349548 Octahydrobenzo[6,7]cyclohept[1,2-b]-1,4-oxazines, compositions and use  
4-Substituted-2,3,4,4a,5,6,7,11b-octahydrobenzo[6,7]cyclohep t[1,2-b]-1,4-ox azines are prepared from the corresponding 6-(substituted amino)-6,7,8,9-tetrahydro-5H-benzocycloheptene-5-ol. The...
4333934 Imidazoquinoxalines and pyrroloquinoxalines  
Novel compounds of the formula ##STR1## wherein A is selected from the group consisting of nitrogen and CH--, G is selected from the group consisting of ##STR2## Z is selected from the group...
4307092 1-Oxo-5H-pyrimido[2,1-C]benzoxazine-2-carboxylic acid esters  
This invention discloses novel 1-oxo-5H-pyrimidol[2,1-c][1,4]benzoxa(or thia)zinc-2-carboxylic acid lower alkyl esters, derivatives thereof, process for their preparation, pharmaceutical...
4282358 Process for the production of substituted N-methylbenzoxazines  
Substituted N-methylbenzoxazines of the formula ##STR1## wherein the ring A can also contain a nitrogen atom as ring member, each of R 1 and R 3 independently is hydrogen, lower alkyl, halogen,...
4276292 Triazolobenzoxazin-4-ones  
New triazolobenzoxazinones are described as well as the use thereof as anti-allergenic agents.
4254118 1-Oxo-5H-pyrimido[2,1-c][1,4]benzthiazine-2-carboxylic acid esters  
This invention discloses novel 1-oxo-5H-pyrimido[2,1-c][1,4]benzoxa(or thia)zine-2-carboxylic acid lower alkyl esters, derivatives thereof, process for their preparation, pharmaceutical...
4254121 3-Oxo-5H-pyrimido[2,1-c][1,4 ]benzoxazines  
3-Oxo-5H-pyrimido[2,1-c][1,4]benzoxazine derivatives, optionally substituted with a hydroxymethyl, carboxy or loweer alkoxycarbonyl at position 1 and optionally substituted at positions 8 or 9,...
4251534 Antihypertensive polyfluorohydroxyisopropyl bicyclic and tricyclic carbostyrils  
Polyfluorohydroxyisopropyl bicyclic and tricyclic carbostyrils, such as 2,3-dihydro-7-methyl-9-[2,2,2-trifluoro-1-hydroxy-1-(trifluo romethyl)ethyl ]-5H-pyrido[1,2,3-de]-1,4-benzoxazin-5-one,...
4246404 Basic indoline dyestuffs  
Basic dyestuffs free of sulphonic acid groups contain an indoline group the 2-position of which is connected through a vinylene group to the N-atom of a 2,3-dihydro-4H-1,4-benzoxazine group. The...
4207318 Novel imidazobenzoxazines  
Novel imidazobenzoxazines of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, halogen and alkyl of 1 to 5 carbon atoms, R is selected from the group consisting of...
4186151 Process for preparing a 5,5'-methylenebis(2-hydroxy-4-alkoxybenzophenone)  
A novel process is provided for preparing 5,5'-methylenebis(2-hydroxy-4-alkoxybenzophenone), comprising forming a novel 2-hydroxy-4-alkoxy-5-aminomethylbenzophenone by a reaction of a...
4171436 Novel degradation products of rubradirin and rubradirin B and process for such degradation  
Disclosed are degradation products of the antibiotics rubradirin and rubradirin B and processes for their preparation. Some of these products have antibacterial activity, and, thus, can be used in...
4171437 Novel degradation products of rubradirin and rubradirin B  
Disclosed are degradation products of the antibiotics rubradirin and rubradirin B and processes for their preparation. Some of these products have antibacterial activity, and, thus, can be used in...
4154829 Aminoalkyl-substituted benzoxazine derivatives  
Racemic and optically active compounds of the formula Q--C n H 2n --NH--R wherein Q is ##STR1## where R 1 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms,...
4134974 Imidazo[5,1-c][1,4]benzoxazin-1-one  
Cyclic derivatives of 1,4-benzoxazine and 1,4-benzothiazine are disclosd, such as, for instance, 1H,2,3,3a,4-tetrahydro-2-carbamoylmethyl-imidazo[5,1-c][1,4] benzoxazin-1-o ne and...
4133954 Pyrrolo- and pyrido-1,4-benzoxazin-3-(2H)-one derivatives as microbicides  
Compounds of the formula I ##STR1## wherein R represents hydrogen, methyl or ethyl and N represents the number 1 or 2 are effective in combatting microbicides.
4133672 (Aminophenyl)morpholines and use thereof  
(2-Aminophenyl)morpholine compounds having a haloalkyl, lower alkylsulfonyl, halo-lower alkylsulfonyl, or branched-chain alkyl substituent on the aromatic ring para to the morpholino nitrogen. The...
4094662 Morpholinobenzimidazole N-oxides  
Tricyclic 1,2-morpholinobenzimidazole N-oxides having a trifluoromethyl or branched-chain alkyl group on the aromatic ring para to the morpholino nitrogen. The compounds are herbicidal and can be...
Matches 151 - 200 out of 235 < 1 2 3 4 5 >