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8134146 |
Heterocyclic radical or diradical, the dimers, oligomers, polymers, dispiro compounds and polycycles thereof, the use thereof, organic semiconductive material and electronic or optoelectronic component
The present invention relates to heterocyclic radicals or diradicals, the dimers, oligomers, polymers, dispiro compounds and polycycles thereof, to the use thereof to organic semiconductive...
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8133847 |
Pyrido[2,3-B]pyrazine derivatives useful as herbicidal compounds
The present invention relates to a method of controlling plants or inhibiting plant growth which comprises applying to the plants or to the locus thereof a herbicidally effective amount of a...
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8105504 |
Stabilization of organic materials
Organic materials which possess outstanding stability to oxidative, thermal or light-induced degradation comprise as stabilizers at least one compound of the formula (I) wherein the general symbols...
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8008315 |
Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer's disease
The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved,...
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7981874 |
Phosphorus derivatives as histone deacetylase inhibitors
The present invention relates to a novel class of phosphorus derivatives. The phosphorus compounds can be used to treat cancer. The phosphorus compounds can also inhibit histone deacetylase and are...
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7977476 |
Methods of attaching biological compounds to solid supports using triazine
Disclosed are methods of attaching biologically active compounds to a solid surface, comprising modifying the solid surface using triazine chloride and attaching the biologically active compound to...
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7901667 |
Bridgehead labelled compounds and methods of using the same
The present invention relates to compounds having the general formula: Y-L-BFR-X wherein BFR is a bridged fused ring system; Y is a targeting group; L is optionally present and is a linker for...
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7863058 |
Methods of attaching biological compounds to solid supports using triazine
Disclosed are methods of attaching biologically active compounds to a solid surface, comprising modifying the solid surface using triazine chloride and attaching the biologically active compound to...
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7795279 |
Method of inhibiting FLT3 kinase
A method of reducing or inhibiting kinase activity of FLT3 in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or...
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7728128 |
Dibenzo[c,h][1,5]naphthyridines and their use as DNA probes
The present invention concerns novel dibenzo[c,h][1,5]naphthyridine of formula (I) and their use as DNA probes, as well as the methods for marking DNA using the same.
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7528137 |
Compounds, compositions, and methods
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
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7504499 |
Methods of attaching biological compounds to solid supports using triazine
Disclosed are methods of attaching biologically active compounds to a solid surface, comprising modifying the solid surface using triazine chloride and attaching the biologically active compound to...
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7498436 |
Substituted hydroxyethylamines
This present invention relates to prodrug compounds of the formula (Y) and pharmaceutical salts thereof: where RN, R1, R2, R3R4 and RC are defined herein, which are useful in treating Alzheimer's...
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7407948 |
Photosensitisers and their uses
Phonoselenazinium compounds of Formula (1): and their use in photodynamic therapy (PDT), particularly as anti-infectives, as anti-cancer agents, and as sterilising agents both for direct use and in...
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7361755 |
Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines
This invention pertains to a novel process for preparing sterically hindered N-substituted alkyloxyamines from alkenes by the transition-metal-catalyzed reaction of a intermediate alkylborane with...
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7345301 |
Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures
The present invention describes new types of material mixtures composed of at least two substances, one serving as a matrix material and the other being an emission material capable of emission,...
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7294738 |
Phosphorous containing steroid mimics
The present invention discloses novel steroid mimics wherein a tri- or tetravalent phosphorous atom is isosterically substituted at any one of the seventeen positions occupied by the carbon atom in...
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7259258 |
Methods of attaching biological compounds to solid supports using triazine
Disclosed are methods of attaching biologically active compounds to a solid surface, comprising modifying the solid surface using triazine chloride and attaching the biologically active compound to...
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7250511 |
Process for the preparation of cyclopenta[g]quinazoline derivatives
Cyclopenta[g]quinazolines of formula (I), and esters and amides thereof may be made by reacting an ester or amide of formula (II); or a protected derivative thereof with a complex containing the...
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7214794 |
Ceramide analogs, process for their preparation and their use as antitumor agents
The present invention is directed to ceramide analog compounds of general formula (I) the process for their preparation and use for the preparation of pharmaceutical formulations for the treatment...
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7186834 |
Substituted iminoazines
The invention relates to novel substituted iminoazines of the general formula (I) in which R1, R2, R3, R4, Z1, Z2 and Z3 are each as defined in the disclosure, to a plurality of processes for their...
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7135047 |
M-phenylenediamine derivatives as coupler components for the coloring of keratinic fibers
Agents for coloring keratinic fibers are provided which contain specific m-phenylenediamine derivatives such as N-2-(morpholine-4-yl)ethyl-m-phenylenediamine,...
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7132295 |
Isotopically coded affinity markers 3
This application relates to isotopically labeled affinity markers of the formula (II) for mass spectrometric analysis of proteins. In formula (II), the groups A, PRG, S, Z, L', Z', R, R', k, l, m,...
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7022849 |
Quinazoline and pyrido[2,3-d]pyrimidine inhibitors of phosphodiesterase (PDE) 7
Quinazoline and pyrido[2,3-d]pyrimidine phosphodiesterase 7 (PDE 7) inhibitors of the following formula wherein R1, R2, L, Y1, Y2, Y3 and Z are as described herein, are provided which are useful in...
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7018840 |
Fluorescent metal sensors, and methods of making and using the same
The present invention is directed, in part, to fluorescent metal sensors for detecting metal ions, and methods of making and using the same.
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6936597 |
Prodrugs of anticancer agents employing substituted aromatic acids
Polymeric prodrugs of the formula: wherein B is selected from the group consisting of OH, leaving groups, residues of amine-containing moieties and a residues of hydroxyl-containing moieties;Y1 is...
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6855503 |
Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing
Exploitation of suitably functionalized heterocyclic molecules, in the design and synthesis of Fluorescence Resonance Energy Transfer (FRET) cassettes and their corresponding dideoxynucleotide...
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6846915 |
Hydroxypyridonate and hydroxypyrimidinone chelating agents
The present invention provides hydroxypyridinone and hydroxypyrimidone chelating agents. Also provides are Gd(III) complexes of these agents, which are useful as contrast enhancing agents for...
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6803447 |
Preparation of supramolecular polymers by copolymerization of monomers containing quadruple hydrogen bonding units with regular monomers
The invention relates to the synthesis of polymers containing self-complementary quadruple hydrogen groups by copolymerizing monomers containing a quadruple hydrogen bonding group with one or more...
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6797522 |
Synthetic receptors
The invention is directed to synthetic receptor(s) which comprises a polyfunctional organic template covalently linked to two or more oligomers which may independently be the same or different and...
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6699979 |
Oligonucleotides having chiral phosphorus linkages
Sequence-specific oligonucleotides are provided having substantially pure chiral Sp phosphorothioate, chiral Rp phosphorothioate, chiral Sp alkylphosphonate, chiral Rp alkylphosphonate, chiral Sp...
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6664398 |
Derivatives of erythromycin, their preparation process and their use as medicaments
A subject of the invention is the compounds of formula in whichY represents a hydrogen atom or a fluorine atom,n represents an integer comprised between 1 and 8,Z represents a hydrogen atom or the...
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6540820 |
Heterocyclic compounds
Compounds of the formula: where R1, R2, R3, R4, R5, R6, R7, R8, R′5, R′6, R′7, R′8 are hydroxy —NO2, —CN, —CF3, —CONH2, C1-12alkyl, phenyl, naphthyl, phenanthryl, anthryl, R9R10N—, R9—O—o...
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6525040 |
Cyclic organoselenium compounds, their preparation and their uses
The invention is directed to novel cyclic organoselenium compounds useful as antioxidants, pharmaceutical compositions containing them, and methods for their preparation.
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6514298 |
Fuel additive and fuel composition
Fuel additives comprise a compound having a group represented by the formula >C═=N— (1). Also disclosed are fuel compositions containing such additives. The additives have a superior detergent eff...
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6486154 |
(Hetero) aryl-sulfonamide derivatives, their preparation and their use as factor XA inhibitors
A compound of formula (I), or a pharmaceutically-acceptable salt thereof, wherein A is an optionally substituted 5- or 6-membered monocyclic aromatic ring containing 1, 2 or 3 ring heteroatoms; B...
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6448241 |
Thiazolobenzoheterocycles, their preparation and medicaments containing them
Compounds of formula (I): their racemates, enantiomers, diastereoisomers and inorganic acid salts and organic acid salts thereof, processes for preparing them and the medicaments containing them...
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6414104 |
Arylamine-substituted poly (arylene vinylenes) and associated methods of preparation and use
The invention provides novel conjugated polymers comprised of arylamine-substituted poly(arylene vinylenes). The polymers have the general structure (I) wherein: Ar is arylene, heteroarylene,...
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6407083 |
Uses of novel organoselenium compounds with pro-oxidant activity
Compounds represented by the following formula I: in which:R1 to R5 can have various meanings of which alkyl, substituted or non-substituted aryl, and m is equal to 0 or 1, X is selected from...
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6375930 |
Membrane incorporation of texaphyrins
Compositions having a texaphyrin-lipophilic molecule conjugate loaded into a biological vesicle and methods for imaging, diagnosis and treatment using the loaded vesicle are provided. For example,...
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6372881 |
Monomers for preparing arylamine-substituted poly(arylene-vinylenes)
The invention provides novel conjugated polymers comprised of arylamine-substituted poly(arylene vinylenes). The polymers have the general structure (I) wherein: Ar is arylene, heteroarylene,...
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6365736 |
Benzoxazine and benzothiazine derivatives and their use in pharmaceuticals
Described are benzoxazine and benzothiazine compounds of the formula I defined herein, methods for their preparation and methods for their use in pharmaceuticals based on their activity as...
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RE37555 |
Process and composition for multicomponent one hundred percent solid fabric softeners
The invention relates to a method of producing a mixture of a quaternary ammonium compound, fatty acid, fatty acid ester and tertiary amine salt in situ which is a highly functional mixture that is...
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6218359 |
Screening method using the RZR receptor family
The current invention concerns the use of a receptor from the RZR/ROR receptor family or of a functional fragment thereof in a test of a compound for anti-autoimmune, anti-arthritic, anti-tumor,...
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6214996 |
Naphthalene derivates, process for the preparation thereof, and intermediates therefor
Naphthalene derivatives of the formula [I]: ##STR1##wherein R1 and R2 are the same or different and are each H, protected or unprotected OH, one of R3 and R4 is protected or unprotected...
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6203578 |
Use of silicon compounds to dye human keratin fibers; novel compounds and compositions containing them
The use of linear or cyclic silicon compounds containing at least one chromophoric group of quinone or azo type as direct dyes in dye compositions intended for dyeing human keratin fibres and in...
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6177494 |
N,N'-disubstituted N-(2-hydroxyalkyl)-ureas
Non-crystallizing N,N'-disubstituted N-(2-hydroxyalkyl)-ureas are used as hydrolysis protection agents in plastics containing ester groups. These disubstituted hydroxy-alkylureas impart excellent...
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6166202 |
Benzophenoxazine dyes
Benzophenoxazine compounds have formula (I) where X is O or NH, Y is NR1 R2 or H, R1 and R2 are alkyl or -L-A, L is a linker and A may be a reactive group by means of which the compound is linked...
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5972912 |
Method for lyophilizing ifosfamide
A method of lyophilizing an oxazaphosphorin and a preparation produced thereby including dissolving an oxazaphosphorin in water, adding an amino acid to a molar ratio of between 1 to 10 amino acid...
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5968920 |
Compounds having a benzisoselen-azoline and -azine structure, method for preparing same and therapeutic uses thereof
The invention concerns novel benzisoselen-azoline and -azine derivatives. These novel derivatives have the following general formula (II): ##STR1## where: R1 to R8 and R10 have various meanings, in...
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