Matches 251 - 269 out of 269 < 1 2 3 4 5 6
Match Document Document Title
4212807 Process for deacylating N-acyl-6-substituted-2-[2-aminoethylthio]-1-carbadethiapen-2-em-3-carbox ylic acids  
Disclosed is a process for chemically cleaving the acyl group from N-acyl-6-substituted-2-[2-aminoethylthio]-1-carbadethiapen-2 -em-3-carboxyl ic acids which proceeds via an imino chloride...
4211707 Process for hydrolytically cleaving O-sulfo thienamycins  
Disclosed is a process for the hydrolytically cleaving O-sulfo thienamycins: ##STR1## wherein R is H or acetyl and M is H, an alkali or alkaline earth metal cation or an organo cationic species...
4210661 Synthetic β-lactam compounds, a process for their preparation and compositions containing them  
This invention provides synthetic β-lactam antibacterial compounds, a process for their preparation and pharmaceutical compositions containing them. The compounds are those of the formula (II):...
4210662 Side chain sulphoxide metabolites  
Compounds of the formula ##STR1## and salts thereof are useful both for their antibacterial activity and as synergists in combination with penicillins and cephalosporins.
4208330 O-Derivatives of thienamycin  
Disclosed are O- derivatives (esters and ethers of the secondary alcohol group) of the antibiotic thienamycin which has the following structure: ##STR1## Such derivatives are useful as antibiotics....
4203902 Process for preparing 6- and 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids  
A process is disclosed for preparing antibiotic 6- and 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids and their pharmaceutically acceptable salts and esters (I) ##STR1## wherein: R 1 and R...
4189493 N-heterocyclic derivatives of thienamycin  
Disclosed are N-derivatives of thienamycin having structures I and II. ##STR1## wherein: the bifunctional radical may contain additional unsaturation in the ring; and wherein n is an integer...
4189473 Antibiotic MM 13902  
It has been found that a novel antibiotic can be obtained by the fermentation of certain strains of Streptomyces olivaceus and related organisms. In addition to being a potent antibiotic this new...
4172144 Schiff's base derivatives of thienamycin  
Disclosed are Schiff's base derivatives of the antibiotic thienamycin, which has the following structure: ##STR1## Such compounds and their pharmaceutically acceptable salt, ester and amide...
4168202 Process for producing antibiotics  
The antibiotics MSD 890A 2 and MSD 890A 5 and pharmaceutically acceptable salts thereof (hereinafter referred to as antibiotics 890A 2 and 890A 5 ) are active against both gram-positive and...
4165379 N-acetyl thienamycin  
The antibiotic N-acetyl thienamycin and its non-toxic pharmaceutically acceptable salts are active against both gram-positive and gram-negative bacteria. The antibiotic is produced by growing a...
4162323 Antibiotic N-acetyl-dehydro-thienamycin  
Antibiotic N-acetyl-dehydro-thienamycin is active against both gram-positive and gram-negative bacteria. The antibiotic is produced by growing a species of Streptomyces in suitable fermentation media.
4162324 Antibiotics 890A.sub.1 and 890A.sub.3  
The antibiotics MSD 890A 1 and MSD 890A 3 and pharmaceutically acceptable salts thereof (hereinafter referred to as antibiotics 890A 1 and 890A 3 ) are active against both gram-positive and...
4153714 3-Thio-5-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylic acid esters, their production and use  
Antibacterial agents have been prepared of the formula (II): ##STR1## wherein R 1 is a group such that CO 2 R 1 is an ester group and R 2 is a hydrocarbon of up to 7 carbon atoms optionally...
4150145 N-alkylated derivatives of thienamycin sulfoxide and sulfone  
Disclosed are N-alkylated derivatives of thienamycin sulfoxide (I, n=1) and sulfone (I, n=2): ##STR1## wherein n=1 or 2; and R 5 , R 6 , and R 7 are, inter alia, hydrogen or alkyl. Such compounds...
4146633 Δ.sup.3 -Thienamycin  
The antibiotic Δ 3 -thienamycin is disclosed: ##STR1## It is prepared by double bond isomerization of thienamycin. Also disclosed are pharmaceutical compositions comprising Δ 3 -thienamycin,...
4146610 Antibiotics MM13902  
It has been found that a novel antibiotic can be obtained by the fermentation of certain strains of Streptomyces olivaceus and related organisms. In addition to being a potent antibiotic this new...
4141986 Antibiotics 890A.sub.2 and 890A.sub.5  
The antibiotics MSD 890A 2 and MSD 890A 5 and pharmaceutically acceptable salts thereof (hereinafter referred to as antibiotics 890A 2 and 890A 5 ) are active against both gram-positive and...
4123547 Thienamycin sulfoxide and sulphone  
Thienamycin sulfoxide (I, n=1), Thienamycin sulfone (I, n=2), and their pharmaceutically acceptable salts are disclosed to be useful as antibiotics: ##STR1## Also disclosed are processes for the...
Matches 251 - 269 out of 269 < 1 2 3 4 5 6