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8163898 |
4-sulfonylpiperidine derivatives
[PROBLEMS] To provide compounds useful as preventives or remedies for circulatory diseases, nervous diseases, metabolic diseases, reproductive system diseases, and digestive diseases.[MEANS FOR...
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8157950 |
Aldimine and composition containing aldimine
Aldimines of Formula (I), which can be used as latent curing agents in curing compositions, for example, in moisture-curing polyurethane compositions that have isocyanate groups. The aldimines are...
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8129519 |
Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof
Chemical agents, such as disulfonamide derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine, and similar heterocyclic ring structures, including salts thereof, that act as...
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8119659 |
(2S,3R)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide, novel salt forms, and methods of use thereof
The present invention relates to (2S,3R)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-
yl)benzofuran-2-carboxamide, novel salt forms thereof, methods for its preparation, novel...
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8105504 |
Stabilization of organic materials
Organic materials which possess outstanding stability to oxidative, thermal or light-induced degradation comprise as stabilizers at least one compound of the formula (I) wherein the general symbols...
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8084266 |
Method and apparatus for separating isomers of chiral substance
In order to realize a method and an apparatus, each of which requires no contact treatment and no chemical reaction, for separating isomers of a chiral substance by irradiating a chiral substance...
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8067582 |
Fused heterocyclic compounds useful as modulators of nuclear hormone receptor function
Disclosed are fused heterocyclic compounds of Formula (I) or pharmaceutically-acceptable salts or stereoisomers thereof. Also disclosed are methods of using such compounds in the treatment of at...
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8053459 |
Selenolopyrazole derivatives and use thereof as anticancer agents
The present invention synthesizes a series of selenolo[3,2-c]pyrazole and selenolo[2,3-c]pyrazole derivatives, and discovers their anticancer activity.
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8049005 |
Substituted tetrahydropyrazolo-pyrido-azepine compounds
The present invention relates to substituted tetrahydropyrazolo-pyrido-azepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical...
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8003631 |
Composition and method for the treatment of tauopathies
The present invention refers to the use of a specific indolocarbazole compound of general formula (1) or a pharmaceutically-acceptable a salt thereof for the preparation of a pharmaceutical...
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7935722 |
Tetrahydrocarbazole derivatives useful as androgen receptor modulators
The present invention provides a compound of the formula: Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of...
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7923442 |
Glutathione peroxidase mimetics and uses thereof
This invention relates to novel organoselenium and tellurium compounds, processes of producing the same and methods of use thereof. The compounds function as mimetics for the catalyst selenoenzyme...
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7906500 |
Chalcogenoxanthylium dyes for purging blood pathogens and for photodynamic therapy
Provided are chalcogenoxanthylium compounds which can effectively be used as sensitizers in photodynamic therapy, virucides in photodynamic antimicrobial chemotherapy and reversal agents of Pgp...
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7879995 |
Tetraphenylene compounds for organic electroluminescent device
An organic electroluminescent device, which has, between a pair of electrodes, at least one organic layer including a light-emitting layer, in which the organic layer contains a specific...
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7777030 |
Compositions and methods for the treatment and prevention of disease
The present invention relates to various novel substituted dipeptide derived nitrogen-containing heterocyclic compounds, their pharmaceutically acceptable salt derivatives, and their methods of...
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7732433 |
Biologically active complex
The invention relates to an aqueous solution containing at least one species selected from the group consisting of a 1:1 molar complex of TeO2 with a moiety of formula (A) and ammonium salts...
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7485283 |
Contrast agents for myocardial perfusion imaging
The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds...
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7465747 |
Fluorescent label compounds
It is intended to provide novel labeling reagents characterized by having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active...
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7408058 |
Regioisomerically pure oxochlorins and methods of synthesis
A method of making an oxochlorin comprises the steps of oxidizing a chlorin to produce a mixture of hydronchlorin and oxochlorin, and then oxidizing the hydroxychlorin in said mixture, preferably...
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7385053 |
Functionalized compositions for improved immobilization
The present invention relates to improved covalent coupling of two or more entities such as biomolecules, polymer compositions, organic/inorganic molecules/materials, and the like, including their...
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7345301 |
Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures
The present invention describes new types of material mixtures composed of at least two substances, one serving as a matrix material and the other being an emission material capable of emission,...
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7314929 |
Organoselenium compounds for cancer chemoprevention
A compound containing an alkylene selenocyanate or an alkylene isoselenocyanate moiety effective to prevent the occurrence or progression of cancer or a precancerous condition. The compound can be...
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7160732 |
Fluorescein-based metal sensors, and methods of making and using the same
The present invention is directed, in part, to fluorescein-based ligands for detection of metal ions, and methods of making and using the same.
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7078130 |
Metallic mesoporous transition metal oxide molecular sieves, room temperature activation of dinitrogen and ammonia production
This invention provides novel stable metallic mesoporous transition metal oxide molecular sieves and methods for their production. The sieves have high electrical conductivity and may be used as...
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7033564 |
Lithium aluminum hydride-based selenating reagent and preparation methods using same
A selenating reagent obtained by reacting lithium aluminum hydride with selenium powder in an organic solvent. In addition, a method for preparing a selenating reagent includes reacting lithium...
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6894039 |
Selenophene anti-tumor agents
Novel selenophene compounds useful as anti-tumor agents are described. Preferred compounds include compounds of formula I: wherein R1 and R2 are independently selected from the group consisting of;...
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6894063 |
Substituted urea neuropeptide Y Y5 Receptor antagonists
A novel class of compounds such as antagonists of the neuropeptide Y Y5 receptor, methods of making such compounds, pharmaceutical compositions containing one or more such compounds, methods of...
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6803447 |
Preparation of supramolecular polymers by copolymerization of monomers containing quadruple hydrogen bonding units with regular monomers
The invention relates to the synthesis of polymers containing self-complementary quadruple hydrogen groups by copolymerizing monomers containing a quadruple hydrogen bonding group with one or more...
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6689174 |
N-benzyl-p-phenylenediamine-derivatives containing coloring agents for keratin fibres and novel n-benzyl-p-phenylenediamine-derivatives
Dyes, containing N-benzyl-p-phenylenediamine derivatives of the general formula (I) or their physiologically compatible salts, for keratin fibers, and new N-benzyl-p-phenylenediamine derivatives.
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6676925 |
Sigma-2 receptors as biomarkers of tumor cell proliferation
Detectably-labeled compounds of formula (I) wherein A,B,C,D,E,F,R,X,Y and Z have any of the meanings given in the specification, and their pharmaceutically acceptable salts, are useful in...
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6576730 |
Organic initiators and their use in the polymerization of unsaturated monomers
Process for the polymerization of unsaturated vinyl and/or vinylidene monomers which comprises reacting one or more monomers in the presence of heterocyclic initiators having a nitrogen atom bound...
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6514298 |
Fuel additive and fuel composition
Fuel additives comprise a compound having a group represented by the formula >C═=N— (1). Also disclosed are fuel compositions containing such additives. The additives have a superior detergent eff...
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6506567 |
Water-soluble flourescent intercalator compound
A water-soluble fluorescent intercalator compound having the formula: F—La—X F is a fluorescent moiety, X is a divalent cyclic group, and La is a linking group, and at least one of X and La has a s...
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6469065 |
Nitrosated and nitrosylated α-adrenergic receptor antagonist, compositions and methods of use
The present invention describes novel nitrosated and/or nitrosylated α-adrenergic receptor antagonists, and novel compositions containing at least one nitrosated and/or nitrosylated α-adrenergic r...
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6455573 |
Glycosidase inhibitors and methods of synthesizing same
A method for synthesizing Salacinol, its stereoisomers, and non-naturally occurring selenium and nitrogen analogues thereof having the general formula (I): The compounds are potentially useful as...
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6383230 |
Cationic monobenzenic dyes, their use for the oxidation-dyeing of keratin fibers, dye compositions and dyeing processes
The invention relates to novel monobenzenic dyes including at least one cationic group Z, Z chosen from quaternized aliphatic chains, aliphatic chains including at least one quaternized saturated...
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6375930 |
Membrane incorporation of texaphyrins
Compositions having a texaphyrin-lipophilic molecule conjugate loaded into a biological vesicle and methods for imaging, diagnosis and treatment using the loaded vesicle are provided. For example,...
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6355631 |
Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and their preparation
The present invention relates to pharmaceutical compositions containing, as an active ingredient, at least one compound of formula: in which R1 represents a radical —N(R4)R5, —N(R4)—CO—R5, —N(R4)—...
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6337394 |
Compounds
There is provided compounds of formula I, wherein R1, R2, R3, Rx, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as...
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6274738 |
Carboxamide derivatives having aryl and thiazole rings
The invention provides DNA primase assays suitable for identifying DN primase modulating agents, methods of modulating DNA primase activity, compounds for modulating DNA primase activity, and...
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6258775 |
Bi-aromatic compounds, pharmaceutical and cosmetic compositions containing same and uses
The invention relates to novel biaromatic compounds having general formula I ##STR1##and their use in pharmaceutical compositions for use in human and veterinary medicine, in particular for...
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6242561 |
Substituted polythiophenes, processes for their preparation their use
Novel polythiophene-containing structural units of the general formulae (I) and (II) ##STR1##processes for their preparation, monomers for their preparation, their use in various industrial fields,...
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6197922 |
Polyselenophenes, the preparation thereof and the use thereof
Novel polyselenophenes comprising one or more structural units of the formulae (I) or (II) or (I) and (II) ##STR1##processes for preparing them, monomers for their preparation, their use in various...
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6187928 |
Imidazolium cations and uses therefor
Novel imidazolium compounds of the formula ##STR1##wherein A represents the atomic group necessary to form a heteroaromatic ring, which may be optionally substituted by one or more R substituents...
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6166003 |
Heterocyclic compounds for cancer chemoprevention
A compound comprising a heterocyclic moiety, such as a thiophene, covalently attached to an alkylene isothiocyanate moiety. The compound is effective to prevent the occurrence or progression of...
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6107345 |
Benzocyclobutane compounds
A compound of formula (I): ##STR1## wherein: Z1, Z2, Z3, Z4, which may be identical or different, represent a group as defined in the description, X represents oxygen, S(O)p, --(CH2)n -- or --CH2...
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6087510 |
Method of use of imidazolium cations
Methods of preparation of dyed textiles, fluorescent polymer matrices, fluorescent clonal markers, non-lineal optical polymers and diagnostic imaging agents are described using compounds with the...
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6042620 |
p-diaminobenzene derivative compounds and dye compositions containing same
New p-diaminobenzene derivative compounds of the formula (I): ##STR1## and physiologically compatible water soluble salts thereof are described, wherein X represents oxygen, sulfur, selenium or...
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5981776 |
Heterocyclic biaryl compounds, pharmaceutical and cosmetic compositions containing them and uses thereof
The invention relates to novel heterocyclic biaryl compounds which have the general formula (I): ##STR1## as well as to the use of these compounds in pharmaceutical compositions intended for use in...
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5977351 |
Benzpyrylium squarylium and croconylium dyes, and processes for their preparation and use
Dyes comprising an inner salt of a compound of the formula: Q1 =Z-Q2wherein: Q1 is a 4-(benz[b]-4H-pyrylium)methylidene, 4-(benz[b]-4H-thiopyrylium)methylidene or...
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