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7388001 |
Halide-free glucosamine sulfate compositions and methods of preparation
Glucosamine sulfate having a purity of at least about 99 wt. %, and a maximum halide content of about 0.01 wt. %. Preferably, the glucosamine sulfate is stabilized by coating it with at least one...
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7388000 |
Halide-free glucosamine phosphate compositions and methods of preparation
Glucosamine phosphate having a purity of at least about 99 wt. %, and a maximum halide content of about 0.01 wt. %. Preferably, the glucosamine phosphate is stabilized by coating it with at least...
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7365188 |
Process for producing N4-Acyl-5′-deoxy-5-fluorocytidine
The present invention provides a process for producing a N 4 -acyl-5′-deoxy-5-fluorocytidine compound of the formula:
where R 2 is alkyl, cycloalkyl, aralkyl, aryl, or alkoxy.
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7348424 |
Polysaccharide containing phosphorylcholine group and process for producing the same
The present invention is a method for manufacturing a phosphorylcholine group-containing polysaccharide wherein the aldehyde derivative-containing compound obtained by the oxidative ring-opening...
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7345165 |
Method for preparing water-soluble free amine chitosan
A method for the preparation of water-soluble chitosan with high purity and biological activity includes steps of: reacting chitosan oligo sugar acid salt, covalently bonded to an organic or...
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7335766 |
Method for producing a chitosan containing salt having a function of lowering blood pressure
The present invention relates to a method for producing a chitosancontaining salt having the function of lowering blood pressure. The method comprises the steps of: (a) dissolving an acid-soluble...
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7304148 |
Sugar chain asparagine derivatives, sugar chain asparagine, sugar chain, and processes for producing these
An asparagine-linked α2,3-oligosaccharide having undeca- to hepta-saccharides, an asparagine-linked α2,6-oligosaccharide having undeca- to hepta-saccharides and containing fluorine and an...
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7288640 |
Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor
This invention relates to processes for production of alkylamino glucosaminide phosphate compounds, and of disaccharide compounds, including various novel intermediates and intermediate processes....
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7288532 |
Modified chitosan polymers and enzymatic methods for the production thereof
The present invention is directed to homogeneous phase enzyme-catalyzed processes for producing modified chitosan polymers or oligomers. An enzyme is reacted with a phenolic substrate in the...
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7285661 |
Starch derivatives, starch active substance conjugates, method for the production thereof and their use as medicaments
The invention relates to starch derivatives of formula (I), in which: X represents a bromine or iodine atom; R″ represents a straight-chain or branched alkyl group, aryl group or aralkyl group,...
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7285659 |
Process for the preparation of D-ribavirin
A process for the preparation of ribavirin on an industrial scale is described which comprises the reaction of glycosylation of 3-substituted triazoles in the presence of a Lewis acid. Said process...
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7273934 |
Three-branched sugar-chain asparagine derivatives, the sugar-chain asparagines, the sugar chains, and processes for producing these
A 3-branched asparagine-linked oligosaccharide derivative of the formula (1) wherein the nitrogen of amino group of asparagine is modified with a lipophilic protective group, biotin group or FITC...
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7253278 |
Purification process for manufacturing a high pure acarbose
A process for purifying and preparing highly pure acarbose from acarbose-containing fermentation broth. The acarbose is purified through steps of alcohol precipitation, a strongly acidic cation...
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7235647 |
Intermediate and process for preparing of β- anomer enriched 21-deoxy,21,21-difluoro-D-ribofuranosyl nucleosides
The present invention provides a highly stereoselective, simple and economical glycosylation process for preparation of β-anomer enriched 2 1 -deoxy-2 1 ,2 1 -D-ribofuranosyl difluoronucleosides...
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7214791 |
Method for preparation of 2′-deoxy-2′, 2′-difluoro-β-cytidine or pharmaceutically acceptable salts thereof by using 1,6-anhydro-β-d-glucose as raw material
The present invention provides a method for preparation of 2′-deoxy-2′,2′-difluoro-β-cytidine or pharmaceutically acceptable salt thereof, comprising starting from 1,6-anhydro-β-D-glucose...
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7196178 |
Sugar-derived gellant for hydrogel formation
A gelatinizer having gel-forming capability in both organic solvents and water, is provided. The hydrogelatinizer is represented by:
(where, A is a sugar residue, and R is an alkyl group).
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7195675 |
Chitosan-containing polysaccharide, method for preparing the same and use thereof
The present invention herein provides a chitosan-containing polysaccharide and a method for the preparation thereof as well as a medicine and a food containing the polysaccharide. The...
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7169919 |
Process for preparing lipid II
A process is described for preparing a substrate for the transglycosylase enzymes of bacterial cell wall biosynthesis. The chemical synthesis makes available a sustainable and substantially pure...
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7157444 |
Aminosalicylate derivatives for treatment of inflammatory bowel disease
Therapeutic 5-aminosalicylic acid derivative compositions having general formula (I), wherein R is a 1-deoxy sugar residue or a poly(ethylene glycol) chain-containing residue, are provided. The...
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7157443 |
Staphylococcus aureus exopolysaccharide and process
A high molecular weight polysaccharide intracellular adhesin (SAE) antigen having the general structure of poly-1,6,β-2-amidoglucopyranoside, which is variable substituted with N-acetyl and...
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7153840 |
Aqueous fludarabine phosphate composition
This invention is directed towards a ready-to-use aqueous composition of fludarabine phosphate. In one embodiment, the invention is directed to an aqueous fludarabine phosphate composition which...
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7148207 |
Oral fludara of high-purity formulation with quick release of active ingredient
This invention relates to a quick-release tablet formulation with >99.19% pure fludara (high-purity fludara) as an active ingredient in a defined composition of residual contaminants.
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7125967 |
Water-soluble chitosan having low endotoxin concentration and methods for making and using the same
Water-soluble chitosan having a low concentration of endotoxin is disclosed. Products containing the water-soluble chitosan are also disclosed. Methods of making and using water-soluble chitosan...
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7125860 |
Cross-linked derivatives of hyaluronic acid
The present invention describes a new class of cross-linked derivatives of partially N-deacetylated hyaluronic acid or derivatives thereof, comprising at least one repeating unit of formula (I)...
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7105661 |
Process for manufacturing morpholino-nucleotides, and use thereof for the analysis of and labelling of nucleic acid sequences
The invention relates to the use of morpholino-nucleosides of formula:
in which R 1 represents a nucleic base and R 2 represents a group corresponding to one of the following formulae:
...
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7091335 |
Derivatized reduced malto-oligosaccharides
Disclosed are derivatized malto-oligosaccharides and methods for the preparation thereof. In accordance with the disclosed invention, a malto-oligosaccharide is hydrogenated to thereby obtain a...
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7091334 |
Method for large-scale production of di(uridine 5′)-tetraphosphate and salts thereof
The present invention provides new methods for the synthesis of the therapeutic dinucleotide, P 1 ,P 4 -di(uridine 5′)-tetraphosphate, and demonstrates applicability to the production of large...
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7053068 |
Chitosan-thio-amidine conjugates and their cosmetic as well as pharmaceutic use
By the reaction of chitosan with iminothiolactones such as 2-iminothiolane, thiol groups can be covalently immobilized on the polymer. The resulting chitosan derivatives exhibit thiol groups which...
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7049434 |
Derivatives of hyaluronan
The invention describes new hyaluronan derivatives where the hydroxyl groups are esterified or carbamoylated in amounts ranging from 0.01% to 100% and the carboxyl groups are either totally or...
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7049433 |
Glucosamine and method of making glucosamine from microbial biomass
Glucosamine suitable for human or animal consumption is disclosed. The glucosamine is derived from microbial biomass containing chitin. Suitable starting materials include substantially uniform...
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7038039 |
Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside
A desired isomer is selectively prepared by phosphorolyzing and isomerizing an anomer mixture of a 1-phosphorylated saccharide derivative while crystallizing one of the isomers to displace the...
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7026471 |
Purification method of hydroxypropylmethyl cellulose phthalate
The present invention relates to a purification method of hydroxypropylmethyl cellulose phthalate, more particularly to a method of preparing high-purity hydroxypropylmethyl cellulose phthalate...
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7005508 |
Nitroderivatives of polysaccharides
The present invention provides a new class of compounds presenting a high compatibility with tissues and organic fluids. Such new compounds are polysaccharides essentially formed of units of uronic...
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6979734 |
Use of rubber latex in combination with starch
The present invention relates to rubber latex comprising an amount of starch, which rubber latex has a reduced allergen activity as compared to the same rubber latex without starch. In addition,...
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6972330 |
Chemical synthesis of methoxy nucleosides
Process for chemical synthesis of methoxy nucleosides.
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6951932 |
Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines
The invention provides new methods for synthesis of 2-aralkyloxyadenosines and 2-alkoxyadenosines. The invention is particularly useful for synthesis of 2-[2-(4-chlorophenyl)ethoxy]adenosine....
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6949640 |
Method for synthesizing 2-chloro-9-(2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine
2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin
-9-amine is synthesized by reacting a 2-chloro-6-substituted purine with a protected and activated 2-deoxy-2-fluoro-D-arabinofuranose;...
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6946551 |
Preparation of hyaluronic acid from eggshell membrane
Compositions and methods of preparing compositions containing hyaluronic acid derived from eggshell membrane are disclosed. The compositions can contain essentially pure hyaluronic acid or...
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6933381 |
Method of preparing modified cellulose ether
Process for the production of polysaccharide ethers, e.g. cellulose ethers, are disclosed wherein salts formed during the process, e.g., sodium nitrate or sodium acetate, are converted to their...
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6933372 |
Method to produce a solid form of heparin
The present invention provides a new method to process a solution containing heparin; heparin salts or heparin complexes in a solvent or a mixture of solvents to a solid form of heparin products...
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6921819 |
Polysaccharide crosslinking, hydrogel preparation, resulting polysaccharide(s) and hydrogel(s), uses thereof
The invention relates to a process for the crosslinking of polysaccharides. The process of the invention is a process for the crosslinking of at least one polymer selected from polysaccharides and...
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6916920 |
Process for producing hydrazinomonosaccharide derivatives and use thereof
A process for producing hydrazinomonosaccharide derivatives and use of hydrazines in determining the structures of aldose and ketose monosaccharides located at the reducing ends of saccharides.
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RE38743 |
Mixtures of particular LMW heparinic polysaccharides for the prophylaxis/treatment of acute thrombotic events
Heterogeneous intimate admixtures of sulfated heparinic polysaccharides, well suited for the prophylaxis/treatment of acute thrombotic episodes in a human patient, comprise immixture of sulfated...
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6894160 |
Catalytic process for the modification of carbohydrates, alcohols, aldehydes or polyhydroxy compounds
The invention relates to the industrial conversion of carbohydrates, alcohols, aldehydes or polyhydroxy compounds in aqueous phase. According to the invention a catalytic method is used for the...
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6884882 |
2′-deoxyuridine derivatives and hydrogels formed therewith
A 2′-deoxyuridine derivative of formula I is bioavailable and thermally stable and forms a gel in water at a low concentration; and, can be employed as a drug delivery vehicle:
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6884880 |
Process for the preparation of 9-β-anomeric nucleoside analogs
A process for substantially enhancing the regio and stereoselective synthesis of 9-β-anomeric nucleoside analogs is described. The introduction of the sugar moiety onto a 6-substituted purine base...
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6884788 |
Thiol-modified hyaluronan
The present invention relates to biscarbodiimides, thiourea derivatives, urea derivatives, and cross-linked hyaluronan derivatives having at least one intramolecular disulfide bond, and methods of...
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6878819 |
Fucosylated oligosaccharides and process for their preparation
The present invention relates to a process for the preparation of oligosaccharides or oligosaccharide containing compounds, especially N-acetyl-chitooligosaccharides having a fucosylated...
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6872819 |
Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells
Biomaterials are disclosed comprised of biodegradable, biocompatible, and bioabsorbable non-woven fabric materials for use in surgery for the guided regeneration of tissues. The non-woven fabric...
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6867296 |
Recovery and purification of anhydro sugar alcohols from a vapor stream
This invention concerns a process for recovering and purifying dianhydro sugar alcohols from a vapor stream comprising dianhydro sugar alcohols, such as isosorbide, and water vapor.
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