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7348424 |
Polysaccharide containing phosphorylcholine group and process for producing the same
The present invention is a method for manufacturing a phosphorylcholine group-containing polysaccharide wherein the aldehyde derivative-containing compound obtained by the oxidative ring-opening...
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7335355 |
Antimicrobial agent
A method of identifying an agent that enhances the anti-microbial activity of cationic anti-microbial peptides by blocking the inhibitory effects of the proteinase/glycosaminoglycan pathway, which...
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7288532 |
Modified chitosan polymers and enzymatic methods for the production thereof
The present invention is directed to homogeneous phase enzyme-catalyzed processes for producing modified chitosan polymers or oligomers. An enzyme is reacted with a phenolic substrate in the...
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7259152 |
Methods and compositions using sulodexide for the treatment of diabetic nephropathy
The present invention provides oral formulations of Sulodexide for the treatment of diabetic nephropathy in patients with both insulin dependent and non-insulin dependent diabetes mellitus. Oral...
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7229977 |
Composition for soluble films with a new hydrolyzed polysaccharide
The invention is concerned with film-forming compositions containing hydrolysates of the exopolysaccharide YAS34 for the use in pharmaceutical, veterinary, food, cosmetic or other products like...
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7211662 |
Soluble highly branched glucose polymers and their method of production
The invention relates to soluble highly branched glucose polymers having a reducing sugar content of less than 1%, characterized in that they have a level of α-1,6 glucoside bonds greater than...
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7208593 |
Self-cross-linked alkyl cellulose
A process for producing a self-cross-linking alkyl cellulose derivative, which includes irradiating, with radioactive rays, a mixture of a starting alkyl cellulose derivative (the number of carbon...
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7205284 |
Potent immunostimulants from microalgae
Immunostimulatory polysaccharides can be preferentially extracted from food-grade microalgae using an aqueous ethanol extraction procedure. The resulting preparations exhibit extremely potent...
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7202230 |
Use of hyaluronic acid derivatives in the preparation of biomaterials with a physical haemostatic and plugging activity
The present invention describes the use of polysaccharide derivatives for the preparation of biocompatible and biodegradable biomaterials with absorbent properties for body fluids and physical...
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7196073 |
Imine-forming polysaccharide adjuvants and immunostimulants
The present invention relates to polysaccharide conjugates that comprise: a polysaccharide that binds to surface-receptors present on Antigen Presenting Cells, conjugated to one or more compounds...
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7196072 |
High molecular weight polysaccharide fraction from Aloe vera with immunostimulatory activity
A complex, water soluble polysaccharide fraction having potent immunostimulatory activity isolated from Aloe vera . The polysaccharide fraction has an apparent molecular weight above 2 million...
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7169309 |
Polysaccharides with oxime or amine functions which are used for water treatment and sludge conditioning
The invention relates to a particular polymer which is derived from a copolymer polysaccharide formed by a main chain comprising similar or different anhydrohexose units and branches including at...
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7160517 |
Apparatus and methods for the automated synthesis of oligosaccharides
One aspect of the present invention relates to an apparatus for the efficient synthesis of oligosaccharides on a solid support, e.g., formed by subunit addition to terminal subunits immobilized on...
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7138386 |
Preventives or remedies for arthritis
The present invention relates to pharmaceuticals, foods and drinks, food additives, animal feeds and feed additives comprising an N-acylated hydroxyproline derivative or a salt thereof, and an...
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7132412 |
Treatment of skin diseases using a pharmaceutical preparation in colloidal form
A new use of a suitable colloidal mixture of hyaluronic acids, of different molecular weights mixed together in a proper ratio in the treatment of the cutaneous diseases is described.
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7125860 |
Cross-linked derivatives of hyaluronic acid
The present invention describes a new class of cross-linked derivatives of partially N-deacetylated hyaluronic acid or derivatives thereof, comprising at least one repeating unit of formula (I)...
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7091191 |
Modified hyaluronic acid for use in musculoskeletal tissue repair
The present invention includes hyaluronic acid complexes of a monovalent alkali metal salt of hyaluronic acid and a tetra alkyl ammonium halide that are suitable for incorporation with tissue...
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7053068 |
Chitosan-thio-amidine conjugates and their cosmetic as well as pharmaceutic use
By the reaction of chitosan with iminothiolactones such as 2-iminothiolane, thiol groups can be covalently immobilized on the polymer. The resulting chitosan derivatives exhibit thiol groups which...
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7049414 |
Isolation of lectins
The invention relates to a process for isolating a lectin composition, in particular comprising the mannose-binding lectin (MBL), suitable for using recombinantly produced lectins as starting...
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7030101 |
Compositions of β-glucans and specific antibodies
Compositions and kits comprising combinations of β-glucans and specific immunoglobulins are disclosed. The compositions and kits are useful in methods of preventing or treating infection by a...
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7005513 |
Functionalized glycosaminoglycan polymer and medical instruments and drugs by using the same
The present invention provides a functionalized polymer which can be used extensively in the field of medical drugs as well as medical devices and which is obtainable in an organic synthetic manner...
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7005508 |
Nitroderivatives of polysaccharides
The present invention provides a new class of compounds presenting a high compatibility with tissues and organic fluids. Such new compounds are polysaccharides essentially formed of units of uronic...
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7005426 |
Folic acid-polysaccharide complex, its preparation method and pharmaceutical composition containing the same as active component
The present invention relates to folic acid-polysaccharide complexs and method of preparation thereof, more particularly relates to folic acid-Dextran complexs, method of preparation thereof,...
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7002007 |
Production of high molecular weight hyaluronates
Methods of making high molecular weight hyaluronates are disclosed. The methods include contacting a hyaluronate-containing source with an acid to make an acidic hyaluronate suspension, contacting...
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7001891 |
Biodegradable polycation composition for delivery of an anionic macromolecule
The present invention provides a biodegradable polycation composition for delivery of an anionic macromolecule, comprising a polysaccharide chain having an amount of saccharide units ranging from 2...
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6998392 |
Formulation to treat or prevent parasitic infection
The invention provides a formulation for treatment or prevention of a parasitic infection such as a protozoan or helminths infection, for example: Giardia . The formulation comprises at least one...
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6992183 |
Highly sulfated derivatives of K5 polysaccharide and their preparation
The purification of the E.coli K5 polysaccharide by treatment with isopropyl alcohol and elimination of lipophilic substances is described. The purified product can be used to prepare, after...
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6987181 |
Oxidized polymeric carbohydrates and products made thereof
The present invention relates to a polysaccharide having functional groups, wherein said groups are aldehyde groups formed at positions C 2 and/or C 3 as well as at position C 6 of the...
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6984733 |
Manufacturing process for porous material
A method for the manufacture of a solid porous separation material based on a polysaccharide, said method comprising the steps of: (a) providing an aqueous solution (I) of a polysaccharide, (b)...
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6974805 |
Configuration of glycosaminoglycans
The present invention provides stable glycosaminoglycan (GSG) structures and methods of use of such GAG structures. These structures comprise a core of free GAG, a coating of crosslinked GAG...
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6958325 |
Cationic polysaccharide compositions
The invention provides a polycation composition comprising a polysaccharide chain having an amount of saccharide units ranging from 2 to 2000, at least one oligoamine directly grafted to said...
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6946551 |
Preparation of hyaluronic acid from eggshell membrane
Compositions and methods of preparing compositions containing hyaluronic acid derived from eggshell membrane are disclosed. The compositions can contain essentially pure hyaluronic acid or...
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6933372 |
Method to produce a solid form of heparin
The present invention provides a new method to process a solution containing heparin; heparin salts or heparin complexes in a solvent or a mixture of solvents to a solid form of heparin products...
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6924273 |
Chondroprotective/restorative compositions and methods of use thereof
The instant invention provides a method of treating or preventing osteoarthritis, joint effusion, joint inflammation and pain, synovitis, lameness, post operative arthroscopic surgery,...
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6921819 |
Polysaccharide crosslinking, hydrogel preparation, resulting polysaccharide(s) and hydrogel(s), uses thereof
The invention relates to a process for the crosslinking of polysaccharides. The process of the invention is a process for the crosslinking of at least one polymer selected from polysaccharides and...
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6906045 |
Method for reducing malodor of chondroitin
The present invention relates to a method of removing or masking odor associated with chondroitin derived from marine life. The method comprises blending the chondroitin with citric acid, silicon...
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6906044 |
Regeneration of articular cartilage damaged by grade I and II osteoarthritis by means of the intraarticular application of a mixture of sodium hyaluronate and chondroitin sulfate in a gel vehicle
Methods of treating osteochondral lesions by the intraarticular application of a mixture of sodium hyaluronate and chondroitin sulfate are disclosed.
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6903208 |
Polymers and their use
A substituted polysaccharide comprising β 1-4 linkages having covalently bonded on the polysaccharide moiety thereof, at least one deposition enhancing group which undergoes a chemical change in...
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6903199 |
Crosslinked amide derivatives of hyaluronic acid and manufacturing method thereof
The present invention relates to water-insoluble, crosslinked amide derivatives of hyaluronic acid and manufacturing method thereof, where the amide derivatives of hyaluronic acid are characterized...
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6897189 |
Anti-wrinkle silicone polysaccharide compounds and compositions comprising said compounds
The present invention relates to compounds, and laundry compositions comprising said compounds, which are capable of providing enhanced anti-wrinkle benefits to cellulosic fiber containing fabric,...
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6884788 |
Thiol-modified hyaluronan
The present invention relates to biscarbodiimides, thiourea derivatives, urea derivatives, and cross-linked hyaluronan derivatives having at least one intramolecular disulfide bond, and methods of...
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6878819 |
Fucosylated oligosaccharides and process for their preparation
The present invention relates to a process for the preparation of oligosaccharides or oligosaccharide containing compounds, especially N-acetyl-chitooligosaccharides having a fucosylated...
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6872819 |
Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells
Biomaterials are disclosed comprised of biodegradable, biocompatible, and bioabsorbable non-woven fabric materials for use in surgery for the guided regeneration of tissues. The non-woven fabric...
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6855519 |
Methods for enhancing the production of interferon in cell culture
Methods for enhancing the production of interferons in animal cell culture are described. These methods rely on the manipulation of the cellular levels of certain inducers of interferon production,...
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6846923 |
Oxime-linked polysaccharides and methods of preparing the same
Polysaccharides comprising one or more oxime linkages are provided. Methods for their preparation include the polycondensation of saccharides bearing oxime-forming substituents. In some...
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6846917 |
Solid- and solution-phase synthesis of heparin and other glycosaminoglycans
Described is a modular, general synthetic strategy for the preparation in solution and on a solid support of heparin, heparin-like glycosaminoglycans, glycosaminoglycans and non-natural analogs of...
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6833451 |
Lipopolysaccharides (LPS) extracted from Escherichia coli
Lipopolysaccharides and processes for producting the lipopolysaccharides are provided. The lipopolysaccharide has a lipid A portion, a core oligosaccharide portion, and an O-specific chain having a...
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6765091 |
Oligosaccharides derived from ribose-ribitol-phosphate, and vaccines containing them
The present invention relates to the field of the Medicine, in particular with the chemical synthesis of oligosaccharide mixtures derived of ribose-ribitol-phosphate, which are used as active...
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6750028 |
Anti-fibrotic agent assay
A novel method has been developed for screening anti-scarring and anti-fibrotic agents. This method offers simplicity, it is reproducible and could be adopted to screen large numbers of new...
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6734298 |
Cross-linking process of carboxylated polysaccharides
A process for the preparation of cross-linked polysaccharides containg carboxy groups. The process comprises a first step of activating the carboxy groups in an anhydrous aprotic solvent and then...
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