Matches 201 - 250 out of 518 < 1 2 3 4 5 6 7 8 9 10 11 >
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5354868 Process for the preparation of (+)-hydantocidin and analogs thereof  
Hydantocidin is a potent non-selective herbicidal natural product. This invention provides an efficient method for the enantioselective preparation of (+)-hydantocidin, analogs thereof and...
5354852 Polysaccharide derivative, process for producing the same, and separating agent  
A particulate aromatic or araliphatic carbamate of a polysaccharide having a mean particle diameter of 1 to 200 μm and a specific surface area of 0.5 to 300 m 2 /g is prepared by first dissolving...
5350841 Ganglioside derivatives  
Novel ganglioside derivatives comprised of a basic natural or semisynthetic ganglioside, in which the carboxyl group in the sialic part of the natural or semisynthetic ganglioside is converted into...
5342976 Skin treatment composition  
A composition suitable for topical application to human skin comprises, in addition to a suitable vehicle an active ingredient which can control skin barrier functions. The active ingredient is (a)...
5332812 Solid-phase substrate containing modified heparin  
A solid phase substrate which yields soluble labeled products upon hydrolysis by a glycosaminoglycan endoglycosidase and methods of producing said substrate are comprised in the present invention....
5330977 Di-N-acetyl lysoganglioside compositions  
The invention relates to N-deacetyl-lysogangliosides and physiologically acceptable salts thereof, especially those of formula (I): ##STR1## wherein R represents --CHCH(CH 2 )nCH 3 or --CH 2 ...
5321012 Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance  
Nontoxic substances that block the N-methyl-D-aspartate (NMDA) receptor, e.g., a morphinan such as dextromethorphan or dextrorphan, or that block a major intracellular consequence of NMDA receptor...
5321011 Pentasaccharide phytohormones and methods for their use  
A phytohormone for inducing root hair curling and root nodulation in the roots of leguminous plants particularly in the absence of nitrogen-fixing bacteria. The phytohormone comprises a...
5284941 Process for obtaining glycolipids and phospholipids  
Glycolipids and phospholipids are obtained by dissolving a mixture of complex lipids in a solvent to form a solution and then passing the solution over a boric acid gel. Glycolipids are retained in...
5281702 Di-N-deacetyl-lysogangliosides  
The invention relates to N-deacetyl-lysogangliosides and physiologically acceptable salts thereof, especially those of formula (I): ##STR1## wherein R represents --CHCH(CH 2 )nCH 3 or --CH 2 ...
5280016 Non-anticoagulant heparin derivatives  
A non-anticoagulant (NAC) form of heparin which shows antiproliferative activity with respect to smooth muscle cells is useful in the prevention of restenosis and other conditions benefited by...
5278300 4,6-o-hydroxyphosphoryl-glucosamine derivatives  
4,6-O-hydroxyphosphoryl-glucosamine derivatives as shown in the following formula [I] and their pharmaceutically-acceptable salts: ##STR1## wherein R 1 and R 2 represent a hydrogen atom or a...
5278299 Method and composition for synthesizing sialylated glycosyl compounds  
5275939 Process for producing asialo GM1  
The present invention provides a process for preparing asialo G M1 characterized in that neuraminidase isozyme L is allowed to act on gangliosides to produce asialo G M1 .
5273892 Acid heteropolysaccharide, sulfated polysaccharide and process for producing the same  
An acid heteropolysaccharide P-318 which comprises galactose, galacturonic acid, N-acetylfucosamine and pyruvic acid in a ratio of about 2:3:1:1, a sulfated heteropolysaccharide P-318 having a 10%...
5274086 N-acetyl-β-d-glucosamine derivatives and reagents for determining n-acetyl-β-d-glucosaminidase activity containing the same as effective ingredients  
N-Acetyl-β-D-glucosamine derivatives represented by the formula ##STR1## wherein R 1 denotes a substituted alkyl group of 1 to 4 carbon atoms having a hydroxyl group, carboxyl group, sulfonic...
5264567 GM.sub.3 analogous compound  
GM 3 analogous compound (I) below: ##STR1## wherein one of R 2 and R 3 represents a neuramic acid group represented by general formula (V): ##STR2## R 5 represents ##STR3## or hydrogen; R 6 ...
5254533 Elfamycin  
A compound of the elfamycin family, a process for preparing it and its use in the feeding of monogastric animals.
5252728 Process for obtaining polymers with antiviral activity  
The present invention consists in a process for obtaining polymers with antiviral activity which is characterized in that beginning with oligo or polysaccharides with a specific structure, polymers...
5250672 Contrast agent for NMR imaging  
A polysaccharide chemically joined to a nitroxyl spin label (NSL) compound has use for the preparation of an NMR diagnostic composition. An agent for modifying H 2 O relaxation times in NMR...
5231177 Sodium N-acetylneuraminate trihydrate  
Sodium N-acetylneuraminate trihydrate herein provided is represented by the following formula: ##STR1## The sodium N-acetylneuraminate trihydrate can be prepared, for instance, according to a...
5229373 Use of exogenous gangliosides as a protective factor against toxicity by antitumor drug vincristine  
An agent for prevention or prophylaxis of general toxic effects or chronic neurotoxic effects which are caused by the administration of antineoplastic agents, which is to be given to patients prior...
5218098 5-(α-D-glucopyranosyloxymethyl)-furan-2-carboxaldehyde  
5-(α-D-glucopyranosyloxymethyl)-furan-2-carboxaldehyde (GMF) is produced from isomaltulose by heating a solution of isomaltulose in a strongly polar aprotic solvent in the presence of an acidic...
5218094 Neuronotrophic factor derived from mammalian brain tissue  
A novel neuronotrophic factor having a molecular weight of about 14,000 to 17,000 daltons and an isoelectric point of about 10 is prepared by homogenization of mammalian brain tissue, particularly...
5210072 Muramyl dipeptide derivatives  
The 3-O-[N-acetylmuramyl-D-isoglutaminyl]-1,2-di-O-palmitoyl-sn- glycerol derivative of formula I ##STR1## wherein the carbon atom marked with an asterisk * has the R or, respectively, the S...
5210078 Trifluoromethyl analogs of fucose and uses thereof  
The present invention discloses trifluorofucoses and methods of making the same. Also disclosed are trifluorofucose analogs of fucose-containing oligosaccharides, and conjugates of trifluorofucose....
5208326 8-hydroxy-2H-dibenz(b,f)azepin-2-one dyes  
Disclosed are 8-Hydroxy-2H-dibenz[b,f]azepin-2-one dyes, chromogenic enzyme substrates made from them and methods for preparing the same.
5206356 Inhibitors for alpha-L-fucosyl transferase  
Synthetic glycosaminosyl transferase-V acceptors and inhibitors are disclosed. Minimal trisaccharide inhibitors and acceptors specific for GnT-V, which is associated with the ability of cells to...
5198352 Preparation of antibacterial compositions from glycopeptides  
Antibacterially active compositions are prepared from a proteolytic enzymatic digestate of glycopeptides obtained from a protein isolate enriched with soya glycoprotein 7S or with bean glycoprotein...
5192748 Antibiotics unphenelfamycin and phenelfamycins A-D  
New antibiotics, unphenelfamycin and phenelfamycins A-D, are produced by microorganisms belonging to the genus Streptomyces. The antibiotics have antibacterial activity against gram-positive and...
5191072 Lipid A monosaccharide analogues  
Lipid A monosaccharide analogues of the following general formula: ##STR1## wherein R 1 is a hydrogen atom or a hydroxyl group, 1 is an integer of 8-14, m is an integer of 11-17 integer, and n is...
5188769 Process for reducing the levels of fatty acid contaminants in polyhydroxy fatty acid amide surfactants  
The synthesis of polyhydroxy fatty acid amide surfactants exemplified by the compound C 11 H 23 C(O)N(CH 3 )CH 2 [CHOH] 4 CH 2 OH by reacting a fatty acid ester with an N-alkyl sugar amine can...
5179093 Quinoline-diones  
Compounds of the formula ##STR1## or a pharmaceutically acceptable salt thereof wherein, R is H, halogen, (C 1 -C 6 ) alkyl, N(C 1 -C 6 alkyl/aryl) 2 , OH, O--(C 1 -C 6 ) alkyl/aryl, CH 2 OH,...
5158941 Lipid A analog as stimulant for production of interleukin-1 in human monocytes and tumor cell growth inhibitor  
This invention concerns the use of synthetic Lipid A analog P9132 to activate human monocytes, and inhibit growth of tumor cells.
RE34091 Sialic acid derivatives having active carbonyl group  
A sialic acid derivative having an active carbonyl group represented by the formula [I]: ##STR1## wherein R 1 represents hydrogen or acetyl group; R 2 represents hydrogen, a metal or a lower...
5143841 Ganglioside ceramidase and process for producing same  
This invention provides a novel ganglioside ceramidase which has a substrate specificity at least for GD1a, GM1, GM2 and GM3 and acts at least on GD1a, GM1, GM2 and GM3 and catalyzes the reaction...
5134230 2-Deoxy-2-aminoglucopyranoside derivatives  
A disaccharide compound represented by formula (I): ##STR1## wherein R, R 1 , R 2 , R 3 , R 4 , and R 5 are as defined in the specification and a salt thereof are disclosed. The compound exhibits...
5126330 Sialosyl cholesterol and neuropathy remedy comprising the same  
The present invention relates to a sodium salt of sialosyl cholesterol. The present compound has an excellent high water solubility, and therefore the compound is very useful as a medicine to be...
5120839 Amido-linked oligosaccharide alditols and a process for their manufacture  
The invention relates to amido-linked oligosaccharide alditols, i.e. oligosaccharide alditols with an amido linkage, having the general formula ##STR1## wherein: R 1 =the alditol portion of a...
5104855 Demethylallosamidin and a process for production thereof  
An antifungal compound, demethylallosamidin, represented by the formula: ##STR1## is disclosed. Methods of production and antifungal compositions comprising demethylallosamidin are also provided.
5102883 Pyrimidine biosynthesis inhibitors useful as immunosuppressive agents  
The pyrimidine biosynthesis inhibitors dichloroallyl lawsone, N-(phosphonoacetyl)-L-aspartic acid (PALA), pyrazofurin, and derivatives thereof, are useful as immunomodulatory and anti-inflammatory...
5101026 Ganglioside related compounds and method of producing the same  
The present invention relates to ganglioside related compounds having, for example, the following formula: ##STR1## where R 1 represents H or COCH 3 (hereinafter abbreviated to "AC"); R 2 ...
5077397 Sialic acid derivative with active ester groups  
Sialic acid derivative with active ester groups expressed with the formula [I] ##STR1## Where R 1 denotes hydrogen or an acetyl group, R 2 denotes hydrogen or a lower alkyl group, R 3 denotes C...
5077277 Chemical derivatives of antibiotics LL-E19020 alpha and beta  
Derivatives of antibiotics derived from the microorganism Streptomyces lydicus subspecies tanzanius, referred to as antibiotics LL-E19020 alpha and beta, are produced by chemical reaction. The...
5066794 Process for preparing a disaccharide derivative  
Disaccharide derivatives represented by the formula (I): ##STR1## wherein R 1 CO-- and R 2 CO-- each represents a residue of a straight chain fatty acid having from 8 to 20 carbon atoms and...
5045338 Secondary amide esters as low calorie fat mimetics  
Secondary amide esters of the general formula ##STR1## where A is an organic radical having 2 to 6 carbons, m=1 to 3, n=1 to 3, and each R is, independently, an aliphatic, ether or ester group...
5045532 Inner esters of gangliosides with analgesic-antiinflammatory activity  
A pharmaceutical composition is provided comprising inner ester ganglioside derivatives useful for its peripheral analgesic-antiinflammatory activity in treating pain caused by pathologies of the...
5041427 Lipid A derivatives  
Compounds are disclosed which are useful in a method of treating animals to protect them from the toxic effects of Gram negative endotoxin. They include the diphosphoryl lipid A (DPLA) which can be...
5037973 Bis-aldonamides and process for their preparation  
The invention relates to bisaldonamides, in which the underlying aldonic acids can be linked glycosidically in the 3-, 4- or 6-position with a galactopyranosyl, mannopyransyl, glucopyranosyl or...
5034516 Synthetic antigens of sialic acid and derivatives thereof  
A compound X-Y wherein X comprises sialic acid, a sialic acid derivative or an oligosaccharide terminating in a sialic acid or sialic acid derivative if multibranched at the end of at least the...
Matches 201 - 250 out of 518 < 1 2 3 4 5 6 7 8 9 10 11 >