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8173607 |
Promoter for the production of hyaluronic acid containing ginsenoside compound K
There are provided a promoter containing ginsenoside compound K for the production of hyaluronic acid, and more particularly, a new efficacy of 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol ...
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7994141 |
Compositions comprising compounds of natural origin for damaged skin
The present invention relates to a skin-protecting composition for the damaged skin, comprising glycyrrhizin, quercetin, rosmarinic acid, madecassic acid, chamazulene, bicalein and emodin. The...
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7985848 |
Pharmaceutical composition for preventing and treating diabetes or glucose control abnormality comprising ginsenosides
The present invention relates to a composition for preventing or treating diabetes or blood glucose control abnormality comprising gisenosides Rg3, Rg5, and Rk1 from natural substances; a use of a...
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7884195 |
Method of extracting ginsengnoside Rg2m, pharmaceutical composition including ginsengnoside Rg2, and uses thereof
The present invention provides a method of extracting ginsenoside Rg2, which is applied to mass production. The method of the present invention employs gradient salting-out instead of conventional...
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7833994 |
Ethanol extraction of phytosterols from corn fiber
The present invention provides a process for extracting sterols from a high solids, thermochemically hydrolyzed corn fiber using ethanol as the extractant. The process includes obtaining a corn...
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7811997 |
Composition containing total triterpenoid sapogenins extracted from bamboo, and the preparation method and use thereof
The invention relates to a composition containing total triterpenoid sapogenins extracted from bamboo, the preparation method and use thereof. These total triterpenoid sapogenins are extracted from...
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7666846 |
Cholesterol-containing compounds and their use as immunogens against Borrelia burgdorferi
Unique compounds that can be used for inducing an immune response to Borrelia burgdorferi in a subject by administering a therapeutically effective amount of the glycolipid to the subject. Such...
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7538093 |
Compositions and methods for therapeutic use
A method and pharmaceutical composition for the enhancement of transfer of a therapeutic agent to a cell wherein the therapeutic agent is formulated in a buffer comprising a compound of Formula I:...
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7435816 |
Synthesis of solanum glycosides
The present invention relates to the chemical synthesis of solanum glycosides, in particular to the synthesis of solasonine as well as to novel β-monosaccharide intermediate compounds, of Formula ...
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7416744 |
Extracts, compounds and pharmaceutical compositions having anti-diabetic activity and their use
The invention relates inter alia to pharmaceutical compositions containing an extract obtainable from a plant of the genus Trichocaulon or Hoodia having anti-diabetic activity; and to the use of...
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7390782 |
Methods and products related to metabolic interactions in disease
The invention involves methods of regulating cell growth and division to control disease processes by manipulating mitochondrial metabolism and the expression of cell surface immune proteins. The...
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7355056 |
Transfection agents
The present invention provides compounds, compositions and methods that enhance the transfer of an agent into a cell. The agents can include polypeptides, polynucleotides such as genes and...
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7211663 |
Synthesis of oligosaccharides, reagents and methods related thereto
One aspect of the present invention relates to differentially protected glycosyl phosphates. Another aspect of the present invention relates to the preparation of glycosyl phosphates from glycal...
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7160866 |
Isolation of tigogenin pentaglycoside from Chlorophytum nimonii
The present invention provides a novel saponin tigogenin penta glycoside isolated from the aerial parts of Chlorophytum nimonii and a process for the isolation thereof as well as its use in...
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7144994 |
Manganese superoxide dismutase exon 3-deleted isoforms and nucleic acid molecules encoding the isoforms
A new isoform of manganese superoxide dismutase (MnSOD) and polynucleotides encoding it have been identified. This isoform, MnSOD E3(−), is a splice variant lacking exon 3 of the full length M...
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7091187 |
Compounds, compositions and methods for treatment of inflammatory diseases and conditions
The present invention relates (a) to new compounds represented by Formula I: wherein M represents a macrolide subunit (macrolide moiety) derived from macrolide possessing the property of...
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6992068 |
Cytokine production inhibitors, agents for protecting and promoting liver function, anti-inflammatory agents, immunosuppressants, drugs, cosmetics, foods and food materials
Highly safe cytokine production inhibitors, agents for protecting and promoting liver function, anti-inflammatory agents and immunosuppressants. Brazilian licorice extract and periandrins, which...
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6984725 |
Method for the separation of triglycoalkaloids
In accordance with the present invention there is provided a method for the separation of a triglycoalkaloid in which the triglycoside portion comprises...
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6916791 |
Androgen derivatives and uses thereof
Androgen glycosides provide free, circulatory androgen on oral administration as they are subject to less, first pass breakdown by the liver.
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6897298 |
Method for extracting a compound from a ginseng spp. plant, ginseng or pseudo-ginseng
This invention discloses a compound (I) of the following formula. This invention also includes a method for extracting the compound (I), and a pharmaceutical composition containing the compound...
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6888014 |
Dammarane sapogenins, their use as anti-cancer agents, and a process for producing same
This invention relates to a group of novel sapogenins, their use in anti-cancer applications, and to a process for their production. More particularly, this invention pertains to a novel group of...
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6884885 |
Production of cyclodextrin complexes
The process entails increasing the concentration of cyclodextrin to 15% (w/w) and above to form complexes through a precipitation process in order to increase the yield of complexes, increase the...
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6835715 |
Mammalian dihydroouabain-like factor and therapeutic compositions
A novel mammalian dihydroouabain-like factor is disclosed which substantially fails to cross-react with mammalian ouabain-like factor (OLF) for binding to anti-OLF antibody, but cross-reacts with...
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6833443 |
Gymnemic acid derivatives, process for the preparation thereof and use thereof as medicine
This invention relates to new Gymnemic acid derivatives, their preparation, pharmaceutical composition or extract which contains them, and their medical use, especially the use in the prevention or...
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6784160 |
Biologically active pregnene compounds
The subject invention provides novel compositions of biologically active glycosylated pregnene compounds which can advantageously be used for treating cancer and stopping cell proliferation.
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6784159 |
Triterpene saponins from soybeans for treating kidney disease
A method of treating polycystic kidney disease is described. The method involves administering soyasaponin Bb to an animal in need thereof.
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6753414 |
Process for preparing saponin compounds
A process for preparing compounds of formula (1): including the convergent steps as defined in the specification, and wherein R groups have any of the values defined in the specification. The...
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6720307 |
Glycosylated analogs of fusidic acid
Novel analogs of fusidic acid are described with one or more carbohydrate units attached. Certain glycosylated analogs of fusidic acid have enhanced solubility properties in diluents or excipient...
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6670459 |
Process for the isolation of novel oligospirostanoside
The present invention relates to a process for the isolation of a novel oligospirostanoside structurally constructed as...
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6660720 |
Targeted oligonucleotide conjugates
The present invention provides improved ingress of therapeutic and other moieties into cellular targets. In accordance with preferred embodiments, complexes are provided which carry primary...
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6649745 |
Oligospirostanoside, pharmaceutical composition containing novel oligospirostanoside and method for immunomodulation using said oligospirostanoside
The present invention relates to a novel oligospirostanoside having the structure 3-0-[α-L-rhamnopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→
4)-0-β-D-glucopyranosyl]-25(S)-5β-spirostan-3β-ol isolated...
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6392069 |
Compositions for enhancing delivery of nucleic acids to cells
This invention provides methods and compositions for enhancing transfer of an agent into a cell. The agents can include polypeptides, polynucleotides such as genes and antisense nucleic acids, and...
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6368831 |
Treatment of hyperproliferative disorders
A method of treating a hyperproliferative disorder in a subject in need of such treatment, comprising administering to said subject, in combination, a treatment effective amount of: (a) a...
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6306376 |
Use of arbutin monoesters as depigmenting agents
Arbutin monoesters are employed in a composition for topical application, as a depigmenting and/or bleaching agent for human skin, hair and/or head hair.The invention relates to a method of...
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6274558 |
Method for treating cardiac malfunction
A method of treating cardiac malfunction by administering a positive inotropic effect-producing amount of Hypothalamic Inhibitory factor (HIF).
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6274559 |
Liver protection or treatment agents comprising asiatic acid derivatives as the active component
Compositions and methods of treating or preventing hepatotoxicity utilizing asiatic acid derivatives of Formula 1 are disclosed. ##STR1##
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6262029 |
Chemically modified saponins and the use thereof as adjuvants
The present invention is directed to novel bidesmosidic saponin derivatives comprising a triterpene aglycone core substituted at positions 3 and 28 with a monosaccharide or an oligosaccharide which...
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6150336 |
Steroidal glycosides
The invention relates to certain steroidal glycoside derivatives useful as hypocholesterolemic agents and anti-atherosclerosis agents. The present invention is also directed to pharmaceutical...
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6103884 |
Glycosylated analogs of fusidic acid
Novel analogs of fusidic acid are described with one or more carbohydrate units attached. Certain glycosylated analogs of fusidic acid have enhanced solubility properties in diluents or excipient...
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6093805 |
Glycoside compounds and methods of synthesis
Novel glycosides, especially steroidal and non-steroidal glycosides are provided. The steroidal and non-steroidal glycosides preferably are prepared from aglycons which possess valuable properties...
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6080725 |
Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof
The present invention is directed to vaccines comprising (1) one or more bacterial, viral or tumor-associated antigens; and (2) one or more saponin-lipophile conjugate in which a lipophilic moiety...
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6075132 |
Ursodeoxycholic acid derivatives and methods for producing them
Disclosed are ursodeoxycholic acid derivatives having an increased solubility in water, and methods for producing the derivatives. To produce the derivatives, ursodeoxycholic acid is protected at...
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6027732 |
Iscom or iscom-matrix comprising hydrophobic receptor molecules for antigenic substances
Lipid-containing particles such as iscoms, iscom-matrix or vesicles such as micelles or liposomes that comprise one or more hydrophobic receptor molecules for targeting and antigenic substances,...
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6017906 |
Polyamine conjugates for treatment of infection
The present invention relates to methods of preventing or treating an infection or disease caused by an infectious agent. The present invention also relates to the augmentation of the efficacy of...
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5977081 |
Triterpene saponin analogs having adjuvant and immunostimulatory activity
The present invention is directed to novel chemical compounds in which a lipophilic moiety such as a lipid, fatty acid, polyethylene glycol or terpene is covalently attached to a non-acylated or...
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5948405 |
Fucans with low molecular weight having anticoagulant, antithrombinic and antithromobic activity
Fucans with low molecular weight having anticoagulant, antithrombinic and antithrombotic activity.Fucan sulfates having molecular weight between 14000 and 29000 Dalton show a remarkable...
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5945404 |
21-Substituted steroid compound
A glycoside represented by formula (I), wherein dexamethasone or betamethasone is the aglycon and the 21-position is substituted by a simple sugar or an acylated sugar selected from the group...
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5925537 |
Process for the preparation of metabolites of Ginseng saponins
According to this invention, Prevotella sp. S-1 strain (Bacteroidaceae family, KFCC-10923) is cultured in a medium supplemented with Panax ginseng saponin so as to collect the metabolites of...
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5908833 |
Colon or ileum-specific steroid derivatives
Novel compounds which are a glucocorticosteroid (GCS) chemically bound to a sugar, having the general formula GCS1 --O--Sugar1for colon- or ileum-specific delivery of the GCS to inflamed bowel...
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5874423 |
Digitalis-like compounds
A human cataractous lens nuclei methanolic extract characterized in that it comprises substances having a molecular weight lower than 3000 daltons, inhibiting ATP hydrolysis by Na+,K+ -ATPase...
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