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7531162 |
Transcobalamin receptor binding conjugates useful for treating abnormal cellular proliferation
An agent, composition and method for the treatment, prophylaxis and/or diagnosis of proliferative disorders, which is highly and efficiently absorbed at the site of abnormal cellular proliferation...
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7468432 |
Cobalamin conjugates useful as antitumor agents
The invention provides cobalamin compounds linked to a neutron capture therapy target (e.g. Boron-10 or Gadolinium-157), and optionally linked to a detectable moiety, as well as pharmaceutical...
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6905884 |
Fluorescent cobalamins and uses thereof
The present invention relates to fluorescent cobalamins and uses of these compounds. More particularly, this invention relates to fluorescent cobalamins that comprise a fluorescent, phosphorescent,...
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6613305 |
Radionuclide labeling of vitamin B12 and coenzymes thereof
A compound useful for in vivo imaging of organs and tumors is provided of formula: wherein is a cobalamin, is derived from a corrin carboxylic acid group of said cobalamin, Y is a linking...
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6262253 |
Vitamin B12 conjugates with gcsf, analogues thereof and pharmaceutical compositions
The invention describes complexes between VB 12 analogues and either GCSF or EPO that retain both significant affinity for intrinsic factor (IF) in the VB 12 portion of the complex and...
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5936082 |
Metallocorrinoids as biologically compatible carriers of pharmacological agents
A purified complex of a metallocorrinoid, such as a vitamin B 12 compound, and a pharmacological agent, such as nitric oxide, that is capable of site-specific delivery of the pharmacological agent...
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5869466 |
Vitamin B.sub.12 mediated oral delivery systems for GCSF
The invention describes complexes between VB 12 analogues and either GCSF or EPO that retain both significant affinity for intrinsic factor (IF) in the VB 12 portion of the complex and...
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5869465 |
Methods of receptor modulation and uses therefor
Receptor modulating agents capable of modulating cell surface receptors by affecting the cell surface receptor trafficking pathway are utilized for the treatment and diagnosis of a variety of...
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5840880 |
Receptor modulating agents
Receptor modulating agents capable of modulating cell surface receptors by affecting the cell surface receptor trafficking pathway. The receptor modulating agents are comprised of a covalently...
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5508271 |
Treatment of neurological dysfunction with methylcobalamin
A method for treating neurological dysfunctions associated with AIDS or ARC comprising the administration of methylcobalamin, alone or in combination with methionine. Substantial increases in the...
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5272250 |
Boronated phosphoramidate compounds
A class of pharmaceutically active boronated compounds are provided. The boronated compounds include boronated phosphoramidates, and boronated nucleosides, and oligomers thereof. The compounds are...
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4925931 |
N-homocysteine thiolactonyl retinamido cobalamin and methods of use thereof
N-Homocysteine thiolactonyl retinamido cobalamin is useful for decreasing the induction of chemically-induced tumors in animals. It is also useful for inhibiting weight gain.
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4550163 |
Ligand analog-irreversible enzyme inhibitor conjugates
The present invention encompasses a method for determining ligands in test samples comprising intermixing with the test sample a ligand analog-irreversible enzyme inhibitor conjugate and a binding...
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4465775 |
Vitamin B.sub.12 and labelled derivatives for such assay
Vitamin B 12 in liquid samples, such as human serum or human plasma, is assayed by a competitive binding technique using intrinsic factor and certain labelled vitamin B 12 derivatives. The...
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4364939 |
Derivatives of coenzyme B.sub.12
Novel monoesters of cobamide derivatives of coenzyme B 12 of the formula: ##STR1## wherein R is acyl of an organic carboxylic acid of 4 to 20 carbon atoms and Co is...
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4209614 |
Vitamin B.sub.12 derivative suitable for radiolabeling
Radiolabeled vitamin B 12 derivatives having the formula ##STR1## wherein R is hydrogen or alkyl of 1 to 3 carbon atoms; n is 0, 1, 2, 3 or 4; and the asterisk (*) indicates tagging with a...
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4133951 |
Vitamin B-12 cobalt-57 and process
A method of making radioactively labelled vitamin B-12 by reacting α-(5,6-dimethylbenzimidazolyl)hydrogenobamide with cobaltous ion Co-57, or with another radioactive cobalt isotope. The method...
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3920631 |
Vitamin B12 derivatives having prolonged activity
A vitamin B 12 derivative of prolonged activity is produced by reacting dextran with cyanogen bromide and treating the product with cobamamide.
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3505311 |
CORRINOID COMPOUNDS CONTAINING NO METAL
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3474087 |
FAT SOLUBLE DERIVATIVE OF VITAMIN B12 AND THE PREPARATION THEREOF
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3459855 |
HYDROXOCOBALAMINE COMPLEXES
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3287351 |
Organic nucleotide derivatives and method of manufacturing the same
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3213082 |
Cobamide derivatives
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3132135 |
Preparation of pure dimethyl benzimidazol cobamide adenosine coenzyme
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3130189 |
Hydroxocobalamin-glutathione
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3115489 |
Cyanocobalt and cyanoiron complexes of cobalamin
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3072674 |
Preparation of vitamin b12 derivatives
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3037016 |
B12 coenzymes and processes for preparing the same
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3026316 |
New analogues of vitamin b12 and process for their biosynthesis
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2982766 |
New vitamin b factor
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2967860 |
5-trifluoromethyl derivatives of vitamin b12
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2960446 |
Process for preparing hydroxybenzimidazole by fermentation
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2920015 |
Long-acting vitamin b12
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2879204 |
Vitamin b12 recovery process
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2879203 |
Recovery of vitamin b12 from diluted solutions
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2872444 |
New cobalamins
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2861025 |
Process for obtaining vitamin b12 and vitamin b12-like substances and the products thereof
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2796383 |
Cobalamine analogs and process of preparing the same
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3573276 |
Title is not available
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