Matches 1 - 50 out of 136 1 2 3 >
Match Document Document Title
7399852 Kits and reaction mixtures containing modified probe molecules  
The present invention concerns oligonucleotides containing one or more modified nucleotides which increase the binding affinity of the oligonucleotides to target nucleic acids having a...
7399848 Polynucleotides encoding growth differentiation factor-8  
Disclosed are polynucleotides encoding growth differentiation factor-8 (GDF-8) useful for increasing the muscle mass in chickens.
7399614 5-methylcytosine detection, compositions and methods therefor  
Compositions and methods for detecting 5-methylcytosine in a nucleic acid are disclosed. A 5-methylcytosine discriminator, which is a deoxyribonucleosidetriphosphate comprising a cytosine-pairing...
7399591 Dual resonance energy transfer nucleic acid probes  
Dual nucleic acid probes with resonance energy transfer moieties are provided. In particular, fluorescent or luminescent resonance energy transfer moieties are provided on hairpin stem-loop...
7399589 Immunological detection of RNA:DNA hybrids on microarrays  
The present invention provides a hybridization method and kit for the detection and measurement of biological molecules. A test sample containing the biological molecules of interest is hybridized...
7399587 Canine CYP1A2 genetic polymorphism  
Disclosed is a method for determining whether a dog is an extensive metabolizer or a poor metabolizer in the rate of drug metabolism, by preparing a DNA sample from a dog, and determining a base...
7399584 Method of comparing a target nucleic acid and a reference nucleic acid  
The invention provides methods of comparing a target nucleic acid with a reference nucleic acid using nucleic acid arrays.
7396921 Compositions and kits for detecting a sequence mutation in cinnamyl alcohol dehydrogenase gene associated with altered lignification in loblolly pine  
Loblolly pine ( Pinus taeda L.) is the most important commercial tree species in the USA harvested for pulp and solid wood products. Increasing the efficiency of chemical pulping may be achieved...
7393646 Method, apparatus and system for quantifying the content of genetically modified material in a sample  
A method including providing an initial test sample including a primary material and a relatively smaller amount of at least one adventitious material; combining the initial test sample with a...
7393645 Compositions for the electronic detection of analytes utilizing monolayers  
The present invention relates to the use of self-assembled monolayers with mixtures of conductive oligomers and insulators to detect target analytes.
7393644 Method for real-time detection of polymerase chain reaction  
A method for real-time detection of polymerase chain reaction (PCR) is provided. The method includes: manufacturing a reactor having a plurality of electrodes; immobilizing a PCR primer to surfaces...
7393641 Method of detecting micrometastasis  
A method of detecting micrometastasis of tumor cells in a sample obtained from a region of a subject other than the primary focus of the tumor by using a first primer complementary to part of a...
7393636 Method for forming self-assembly substance using oligonucleotide synthesized by gene amplification reaction, self-assembly substance and method for detecting gene  
There is provided a method for forming a self-assembly substance using oligonucleotides without using special instruments or complicated procedures, an self-assembly substance formed by the method...
7393634 Screening for disease susceptibility by genotyping the CCR5 and CCR2 genes  
Provided are compositions, methods and uses for identifying persons at an increased risk of infection by, transmission of, or accelerated progression of a disease caused by an HIV-1 virus....
7388092 Oligonucleotides and analogs labeled with energy transfer dyes  
Novel linkers for linking a donor dye to an acceptor dye in an energy transfer fluorescent dye are provided. These linkers faciliate the efficient transfer of energy between a donor and acceptor...
7387877 Bio-sensor and bio-sensor reporting system  
A biosensor unit that can be wall mounted in a location to perform testing of ambient air for bio-contaminants. This unit could contain an air filter for collecting contaminants and a...
7387876 Amplification of trace amounts of nucleic acids  
Methods of reducing background during amplification of small amounts of nucleic acids employ careful analysis of sources of low level contamination. Ultraviolet light can be used to reduce nucleic...
7385049 Oligonucleotides and methods for detection of West Nile virus  
The invention provides methods of detecting West Nile virus and oligonucleotide reagents derived from a West Nile virus consensus sequence that are useful in the methods of the invention.
7384749 Electrodes linked via conductive oligomers to nucleic acids  
The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids...
7384748 Compositions and methods for detecting and treating motor neuron disorders  
The present invention relates to the NTE proteins and nucleic acids encoding the NTE proteins. The present invention further provides assays for the detection of NTE polymorphisms and mutations...
7384746 Charge tags and the separation of nucleic acid molecules  
The present invention relates to novel phosphoramidites, including positive and neutrally charged compounds. The present invention also provides charge tags for attachment to materials including...
7384735 Retinoblastoma nucleic acids  
This invention relates to nucleic acid, or fragments thereof, encoding the retinoblastoma polypeptide, the retinoblastoma polypeptide itself, methods of detecting a defective retinoblastoma gene in...
7381819 Composition for treatment or prevention of endometrial cancer and method of preventing or treating endometrial cancer using the composition  
Provided are a composition for the treatment or prevention of an endometrial cancer including a nuclear acid molecule inducing RNA interference against human syndecan-1 gene expression and a...
7381818 Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof  
Minor groove binder-oligonucleotide probes are provided along with methods for their use wherein the probes have an attached fluorophore which, in an unhybridized form exhibits very low background...
7381808 Method and nucleic acids for the differentiation of prostate tumors  
The present invention relates to chemically modified genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method...
7381533 Electrodes linked via oligomers to nucleic acids  
The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids...
7381532 Compositions and methods for the detection of a nucleic acid using a cleavage reaction  
The invention relates to a method of generating a signal indicative of the presence of a target nucleic acid sequence in a sample, where the method includes forming a cleavage structure by...
7381528 Methods for detection of mutations in myostatin variants  
Methods for detecting allelic variants of the myostatin (growth and differentiation factor-8) gene are provided. Specifically provided are methods of identifying subjects having or having a...
7381526 Assays for drug discovery based on microcompetition with a foreign polynucleotide  
A recent discovery showed that microcompetition between a foreign polynucleotide and a cellular polynucleotide is a risk factor for some of the major chronic diseases. The invention uses this novel...
7378517 UV excitable energy transfer reagents  
Novel energy transfer dyes which can be used with shorter wavelength light sources are provided. These dyes include a donor dye with an absorption maxima at a wavelength between about 250 to 450 nm...
7378485 Peptide nucleic acids with polyamide-containing backbones  
A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands...
7378243 Nucleic acid cloning  
The present invention provides an improved system for linking nucleic acids to one another. In particular, the present invention provides techniques for producing DNA product molecules that may be...
7378236 Method for analyzing gene expression patterns  
A method and device for detecting or monitoring the treatment status of a selected physiological state or disease condition. The device has a subarray of genes which show a statistically...
7374945 Method for enhancing the association rates of polynucleotides  
The present invention features a method and associated kit for increasing the association rate between polynucleotides having complementary, single-stranded regions, where the method includes...
7374927 Methods of analysis of degraded nucleic acid samples  
The invention provides arrays for analysis of compromised nucleic acid samples, for example, nucleic acids obtained from formalin fixed paraffin embedded samples and methods to analyzed these...
7374882 Method for base sequencing and biologically active nucleic acids  
Aptamers are nucleic acids and similar molecules, such as peptide-nucleic acids, that specifically bind to a ligand such as a protein or peptide. The present invention provides aptamers comprising...
7374877 Amplification of HIV-1 gag sequences for detection of sequences associated with drug-resistance mutations  
Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of...
7371940 COT102 insecticidal cotton  
The present application relates to an insect resistant transgenic cotton plant. In particular, it relates to a specific event, designated COT102. The application also relates to polynucleotides...
7371851 Methods of cloning and producing fragment chains with readable information content  
The present invention provides a method of attaching a fragment of a first nucleic acid molecule to a second nucleic acid molecule using adapters to mediate the binding particularly in methods of...
7371850 Method and composition for reducing expression of ROCK-II  
Methods and pharmaceutical compositions for treating, and delaying the onset of, viral infection, are provided.
7371580 Use of unstructured nucleic acids in assaying nucleic acid molecules  
The present invention provides a system and methods for assaying nucleic acid molecules with reduced levels of background signal and enhanced specificity and sensitivity. In particular, the present...
7371533 Methods for separation of polymeric compounds  
Recently two techniques using free solution electrophoresis to separate charged-uncharged polymer conjugates have proven successful: End Labeled Free Solution Electrophoresis (ELFSE) for DNA...
7371532 Method and apparatus for determining base sequence of nucleic acid molecule  
Disclosed herein is a method and apparatus for determining the base sequence of a nucleic acid molecule by cleaving a nucleic acid molecule of interest while controlling the cleavage site,...
7371520 Methods and apparati using single polymer analysis  
The invention relates to methods for analyzing and characterizing single polymers such as nucleic acid molecules. In preferred embodiments, the single molecules are analyzed using single molecule...
7368559 FcγRIIA-specific nucleic acid interference  
The present invention provides methods and compositions for attenuating expression of FcγRIIA. In general, the described methodology involves the use of RNAi constructs that are targeted to a...
7368558 PRO357 nucleic acids  
The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising...
7368549 Tm leveling compositions  
Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor...
7368547 Use of novel virulence-specific genes as targets for diagnosis and potential control of virulent strains of Listeria monocytogenes  
A method for identifying virulent strains of L. monocytogenes that includes the use of primers or probes in a PCR assay or hybridization technique that employs primers or probes, which are...
7368245 Method and probes for the detection of chromosome aberrations  
A novel method for detecting chromosome aberrations is disclosed. More specifically, chromosome aberrations are detected by in situ hybridisation using at least two sets of hybridisation probes, at...
7368243 Detection of nucleic acids to assess risk for bovine spongiform encephalopathy  
The present invention provides a method of detecting abnormal serum nucleic acid profiles to assess the risk of a transmissible spongiform encephalopathy, e.g., BSE.
Matches 1 - 50 out of 136 1 2 3 >