Matches 51 - 100 out of 146 < 1 2 3 >
Match Document Document Title
7371580 Use of unstructured nucleic acids in assaying nucleic acid molecules  
The present invention provides a system and methods for assaying nucleic acid molecules with reduced levels of background signal and enhanced specificity and sensitivity. In particular, the present...
7371533 Methods for separation of polymeric compounds  
Recently two techniques using free solution electrophoresis to separate charged-uncharged polymer conjugates have proven successful: End Labeled Free Solution Electrophoresis (ELFSE) for DNA...
7371532 Method and apparatus for determining base sequence of nucleic acid molecule  
Disclosed herein is a method and apparatus for determining the base sequence of a nucleic acid molecule by cleaving a nucleic acid molecule of interest while controlling the cleavage site,...
7371520 Methods and apparati using single polymer analysis  
The invention relates to methods for analyzing and characterizing single polymers such as nucleic acid molecules. In preferred embodiments, the single molecules are analyzed using single molecule...
7368559 FcγRIIA-specific nucleic acid interference  
The present invention provides methods and compositions for attenuating expression of FcγRIIA. In general, the described methodology involves the use of RNAi constructs that are targeted to a...
7368558 PRO357 nucleic acids  
The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising...
7368549 Tm leveling compositions  
Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor...
7368547 Use of novel virulence-specific genes as targets for diagnosis and potential control of virulent strains of Listeria monocytogenes  
A method for identifying virulent strains of L. monocytogenes that includes the use of primers or probes in a PCR assay or hybridization technique that employs primers or probes, which are...
7368245 Method and probes for the detection of chromosome aberrations  
A novel method for detecting chromosome aberrations is disclosed. More specifically, chromosome aberrations are detected by in situ hybridisation using at least two sets of hybridisation probes, at...
7368243 Detection of nucleic acids to assess risk for bovine spongiform encephalopathy  
The present invention provides a method of detecting abnormal serum nucleic acid profiles to assess the risk of a transmissible spongiform encephalopathy, e.g., BSE.
7368242 Method and kits for multiplex hybridization assays  
The invention provides a method for genotyping interfering polymorphic loci in a target polynucleotide, such as a strand of genomic DNA, in a multiplex hybridization-based assay. The invention also...
7368241 Cotton event PV-GHBK04 (757) and compositions and methods for detection thereof  
The present invention provides a cotton event PV-GHBK04 (757), a cotton plant that contains PV-GHBK04 (757) DNA molecules and its progeny thereof, and methods for producing cotton event PV-GHBK04...
7368239 Method and materials for polyamine catalyzed bisulfite conversion of cytosine to uracil  
The invention provides methods and materials for conversion of cytosine to uracil. In some embodiments, a nucleic acid, such as gDNA, is reacted with bisulfite and a polyamine catalyst, such as a...
7365187 DNA amplification method and kit therefor  
In a method for amplifying a DNA, comprising performing PCR using a sense primer and an antisense primer, PCR is performed in the presence of an additional sense primer comprising the sense primer...
7365179 Multiplexed analytical platform  
The invention provides a system and reagents for carrying out multiplexed analytical measurements using the hybridization of oligonucleotide tags to addressable solid phase supports to obtain...
7364855 Methods and kits for methylation detection  
Ligation-based methods and kits are disclosed for determining the degree of methylation of one or more target nucleotides. In certain embodiments, the methylation status of one or more target...
7364852 Short GCG expansions in the PAB II gene for oculopharyngeal muscular dystrophy and diagnostic thereof  
The present invention relates to a human PAB II gene containing transcribed polymorphic GCG repeat, which comprises a sequence as set forth in SEQ ID NO:3, which includes introns and flanking...
7364849 Treatment of substrates for immobilizing biomolecules  
A method of treating a substrate for immobilizing a biomolecule and substrates produced by the method are disclosed. The method includes contacting at least a portion of a substrate with a reducing...
7364844 Use of the Krit1 gene in the field of angiogenesis  
The invention concerns a method for diagnosing cavernous angiomas for detecting mutations in the Krit1 gene. More particularly, said detection is performed by using nucleotide sequences. The...
7361821 Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading  
The methods, apparatus and compositions disclosed herein concern the detection, identification and/or sequencing of biomolecules, such as nucleic acids or proteins. In certain embodiments of the...
7361511 Compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer  
The invention relates to nucleic acid molecules and proteins associated with cervical cancer including pre-malignant conditions such as dysplasia. Compositions, kits, and methods for detecting,...
7361489 Nucleic acid amplification methods  
The present invention relates to assays and kits for carrying out said assays for the rapid, automated detection of infectious pathogenic agents and normal and abnormal genes. The present invention...
7361488 Nucleic acid detection methods using universal priming  
The present invention is directed to providing sensitive and accurate assays for gene detection, genome-wide gene expression profiling and alternative splice monitoring with a minimum or absence of...
7361471 Nucleic acid archiving  
This invention is directed to a process for tightly binding nucleic acid to solid phase and corresponding processes for the utilization thereof. Nucleic acid is bound to solid phase matrices...
7361470 Electrocatalytic nucleic acid hybridization detection  
The detection of specific DNA sequences using electrochemical readout would permit the rapid and inexpensive detection and identification of bacterial pathogens and the analysis of human genes. A...
7361469 Dual labeled fluorescent probes  
The present invention relates to probes useful for the detection and measurement of target nucleic acids, as well as compositions and kits containing such probes. The probes of the present...
7361468 Methods for genotyping polymorphisms in humans  
Methods, kits and arrays of nucleic acid probes for genotyping large numbers of human SNPs in parallel are provided. A set of more than 100,000 human SNPs, known to be biallelic in at least two...
7361467 Methods for detection of a target nucleic acid by capture  
The invention relates to a method of generating a signal indicative of the presence of a target nucleic acid in a sample, where the method includes forming a cleavage structure by incubating a...
7361460 Approach to molecular diagnosis of human papillomavirus-related diseases  
The present invention relates to an accurate, sensitive, and efficient sequential or concurrently sequential method for molecular diagnosis of human papillomavirus (HPV)-based disease, where the...
7358349 Nucleic acids having expression differentials between hepatoblastoma and normal liver  
A nucleic acid comprising any one of base sequences set forth in SEQ ID NO:1 to NO:104 in the Sequence Listing and a protein encoded by the nucleic acid, particularly a nucleic acid displaying...
7358347 MEN1, the gene associated with multiple endocrine neoplasia type 1, menin polypeptides and uses thereof  
The invention relates to the discovery of a novel tumor suppressor gene which is associated with multiple endocrine neoplasia type 1. The gene has been designated MEN1 and the gene product is...
7358047 Methods of forming circular nucleic acid probes and uses thereof  
The present invention relates generally to a method of amplifying closed circular nucleic acid probes and, more particularly, to a method of amplifying closed circular nucleic acid probes by...
7355035 Catalytic molecules  
The present invention relates to DNAzymes which are targeted against mRNA molecules encoding EGR-1 (also known as Egr-1 and NGFI-A). The present invention also relates to compositions including...
7355034 Oligonucleotides for use in determining the presence of human papilloma virus in a test sample  
The present invention describes oligonucleotides targeted to HPV Type 16 and/or Type 18 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 and or 18. The...
7355022 Gene functionally related to dyslexia  
The present invention describes a novel human gene, DYXC1, which is functionally related to dyslexia. DYXC1 gene encodes a 420-amino acid residue protein. DYXC1 is expressed in several tissues,...
7354716 RNA detection and quantitation  
The present invention is directed to a highly sensitive method for direct detection of at least one specific RNA in a sample. The presence of a specific RNA provides a positive indicator of a...
7354715 High-throughput methods of screening DNA for deletions and other mutations  
The subject invention relates to high-throughput methods of screening DNA for mutations. These methods offer various unexpected advantages over current methods. In a preferred embodiment, the...
7354708 Invasion assays  
The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to...
7354707 Nucleic acid probes, method for determining concentrations of nucleic acid by using the probes, and method for analyzing data obtained by the method  
Nucleic acid probes are provided, each of which is formed of a single-stranded oligonucleotide which can hybridize to a target nucleic acid and is labeled with a fluorescent dye or with a...
7351819 Method of detecting norwalk-like virus (GII)  
A method of detecting a virus in a specimen, whereby a Norwalk-like virus (GII) is detected by using as an index the nucleic acids of a complementary nucleotide sequence corresponding to the 4851-...
7351538 Systems and methods for detecting and analyzing polymers  
A detection system and methods for improving the ability of the detection system to recognize labels that are disposed on a polymer. Embodiments of the invention include schemes for selecting...
7351536 Revolver-2: a novel transposon-like element from rye  
The object of the present invention is to obtain a novel transposon-like element specifically present in the genome of rye and the like. According to the present invention, a DNA sequence of a...
7351531 Molecules capable of binding to telomere and the like and method with the use of the same  
A method of forming a self-connective structure (a hairpin structure, a four-stranded structure, etc.) of a single-stranded oligonucleotide chain by forming a mimetic base pair of a mismatch base...
7351528 Probing of specific nucleic acids  
The present invention relates to improved methods for probing of specific nucleic acids using circularizable probes designed such that they report the presence of a target sequence by allowing a...
7348165 Methods for detecting cancer cells by using nucleic acid encoding for IGF-1 receptor interacting proteins  
The invention relates generally to a method for the detection of the proliferation of a tumor cell and more specifically wherein said method comprises nucleic acids (SEQ ID NO:1) encoding IIP-1.
7348149 Methods of diagnosing Parkinson's disease by measuring expression level of RNA encoding human protein HLLRCR-1  
The present invention provides novel polynucleotides encoding HLLRCR-1 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and...
7348148 Nucleic acid derivatives  
A compound which comprises a backbone having a plurality of chiral carbon atoms, the backbone bearing a plurality of ligands each being individually bound to a chiral carbon atom of the plurality...
7348146 Single nucleotide polymorphism analysis of highly polymorphic target sequences  
Methods and probes are provided for the analysis of target sequences having two or more polymorphisms wherein one of the polymorphisms is to be distinguished and another polymorphism is to be masked.
7348142 Cancer diagnostic panel  
A method of diagnosing cancer by identifying differential modulation of each gene (relative to the expression of the same genes in a normal population) in a combination of genes selected from two...
7348141 Hybridization beacon and method of rapid sequence detection and discrimination  
A method for detecting specific DNA sequences and discriminating single nucleotide polymorphisms (SNPs) using fluorescently labelled oligonucleotide probes is disclosed. Oligonucleotide probes are...
Matches 51 - 100 out of 146 < 1 2 3 >