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7148328 |
Compositions and methods for regulating autolytic processes in bacteria
A nucleic acid sequence required for regulating the autolytic activity of bacteria is provided. Also provided are polypeptides encoded by the gene or mutant gene as well as vector and host cells...
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7147848 |
Recombinant poliovirus for the treatment of cancer
The present invention is directed to non-pathogenic, oncolytic, recombinant polioviruses for the treatment of various forms of malignant tumors. The recombinant polioviruses of the invention are...
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7144998 |
Clostridium perfringens beta-2 toxin signal sequence, promoter and recombinant prokarote host cells comprising them
Recombinant polypeptides are prepared using novel nucleic acids with transcription promoter activity. The recombinant cells containing said nucleic acids are described. A novel method for preparing...
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7141408 |
Plasmid maintenance system for antigen delivery
The present invention relates generally to a Plasmid Maintenance System for the stabilization of expression plasmids encoding foreign antigens, and methods for making and using the Plasmid...
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7141410 |
Methods and materials for the production of organic products in cells of Candida species
The present invention relates to biocatalysts that are cells, optimally of the Crabtree-negative phenotype, comprising expression vectors encoding genes heterologous to the cell that enable...
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7141424 |
Solely pollen-specific promoter
An isolated solely pollen-specific promoter derived from Arabidopsis comprise a nucleotide sequence of Arabidopsis PLA 2 -δ gene. The novel promoter has specific roles in particular organs and...
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7141722 |
Glyphosate resistant plants using hybrid promoter constructs
The present invention relates to novel plant expression constructs. More specifically the present invention provides DNA constructs comprising 5′ regulatory sequences for modulating the...
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7141661 |
Non-steroidal anti-inflammatory drug activated gene with anti-tumorigenic properties
The present invention provides methods and compositions for drug screens to identify and characterize agents that are agonistic or antagonistic to activation of the promoter region of the NAG-1...
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7141405 |
Chimeric GB virus B (GBV-B)
The present invention relates generally to the fields of biochemistry, molecular biology, and virology. More particularly, it relates to the identification of GB virus B (GBV-B)/HCV chimeras. The...
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7141377 |
Process for discrimination of nucleic acid sequence variants
A process of detecting a target nucleic acid using labeled oligonucleotides uses the 5′ to 3′ nuclease activity of a nucleic acid polymerase to cleave annealed labeled oligonucleotide from...
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7138273 |
Method of identifying non-host plant disease resistance genes
The invention describes a new method to isolate disease resistance genes in plants. The method teaches to transiently express in susceptible plants large numbers of R-gene homologs or non-host...
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7138112 |
Plasmid maintenance system for antigen delivery
The present invention relates generally to a Plasmid Maintenance System for the stabilization of expression plasmids encoding foreign antigens, and methods for making and using the Plasmid...
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7138278 |
Maize cytoplasmic glutamine synthetase promoter compositions and methods for use thereof
The current invention provides the promoter of the Zea mays nuclear gene encoding glutamine synthetase. Compositions comprising this sequence are described, as are plants transformed with such...
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7138380 |
Transgenic animals and cell lines for screening drugs effective for the treatment or prevention of Alzheimer's disease
Disclosed are transgenic animals and transfected cell lines expressing a protein associated with Alzheimer's Disease, neuroectodermal tumors, malignant astrocytomas, and glioblastomas. Also...
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7135562 |
Avian iFABP gene expression controlling region
A recombinant nucleic acid is provided having an avian promoter. One embodiment of the present invention contemplates the use of a gut-specific promoter, wherein a promoter can be the chicken...
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7135620 |
Genetic engineering of plant chloroplasts
Novel chimeric constructions and methods for their use are provided for expression of exogenous genes in a plant chloroplast. Particularly, expression is achieved by the use of a chloroplast or...
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7135613 |
Chimeric gene constructs for generation of fluorescent transgenic ornamental fish
Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed, respectively, were isolated and ligated to the 5′ end of the EGFP...
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7132292 |
Anther-specific promoter from the rice TUB8 gene and uses thereof
The present invention provides novel anther-specific genes, their promoters, and uses of the same. Rice seedlings were treated with gibberellin, and then genes and proteins with up-regulated...
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7132528 |
Promoter from the rice triosephosphate isomerase gene OsTPI
The present invention relates to polynucleotide molecules for regulating gene expression in plants. In particular, the invention relates to DNA sequences of the rice ( Oryza sativa cv Nipponbare)...
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7132526 |
Isolation and characterisation of an anther-specific promoter (CoFS) in cotton
The present invention relates to an anther-specific cotton gene (CoFS), and active promoter fragments thereof. These promoters show strong anther-specific activity.
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7132530 |
Antisense modulation of superoxide dismutase 1, soluble expression
Antisense compounds, compositions and methods are provided for modulating the expression of superoxide dismutase 1, soluble. The compositions comprise antisense compounds, particularly antisense...
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7132522 |
Regulatory sequences and expression cassettes for yeasts, especially for kluyveromyces
The invention relates to a DNA sequence which acts as a promoter in yeast cells, to an expression and optionally, secretion system containing said DNA sequence, to plasmids containing this system,...
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7132521 |
Molecular regulatory circuits to achieve sustained activation of genes of interest by a single stress
The exposure of cells, tissues and organs to “stress,” such as elevated temperature, stimulates production of active heat stress transcription factors (HSF), which in turn, induce expression of...
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7132527 |
Promoter and plasmid system for genetic engineering
This invention provides a series of low-copy number plasmids comprising restriction endonuclease recognition sites useful for cloning at least three different genes or operons, each flanked by a...
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7129397 |
Promoters functional in plant plastids
The present invention relates to isolated nucleic acid molecule comprising a nucleic acid promoter or untranslated region comprising the nucleic acid sequence of SEQ ID NO: 1, 2 or 3. The invention...
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7129342 |
Infectious cDNA clone of GB virus B and uses thereof
The present invention relates to nucleic acid sequence which comprises the genome of an infectious GB virus B clone. The invention also relates to the use of the nucleic acid sequence of the...
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7129060 |
Export systems for recombinant proteins
The present invention relates to vectors, host-vector combinations and processes for preparing stable fusion proteins consisting of a carrier protein and a passenger protein, where expression of...
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7129343 |
Bi-directional dual promoter complex with enhanced promoter activity for transgene expression in eukaryotes
The present invention is directed to bidirectional promoter complexes that are effective for enhancing transcriptional activity of transgenes. The bidirectional promoters of the invention include a...
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7129089 |
Annexin and P34 promoters and use in expression of transgenic genes in plants
A seed specific plant annexin and P34 promoters and subfragments thereof, recombinant expression construct comprising these promoters and their use in driving seed-specific expression of one or...
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7129083 |
PiggyBac transformation system
The present invention is directed to a transformation systems and vectors for making transgenic organisms that includes a vector containing a modified piggyBac transposon into which is inserted at...
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7129062 |
Matrix attachment regions and methods for use thereof
The present invention relates to compositions and methods for transfecting eukaryotic cells with nucleic acid vectors. In particular, the invention relates to the uses of Matrix Attachment Region...
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7125978 |
Promoter for regulating expression of foreign genes
The present invention relates to a promoter for regulating expression of foreign genes in transgenic organisms, which comprises a promoter having the identifying characteristics of a promoter...
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7125979 |
Upstream control elements of the proopiomelanocortin gene and their use
The nucleic acid sequence of the POMC enhancer is disclosed herein. Sequences from the human, rat, rabbit, hamster, mouse, and cow POMC enhancer are disclosed. Hybrid transgenes, comprising a POMC...
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7125980 |
Nucleic acid fragments for the identification of bacteria in industrial wastewater bioreactors
Unique bacterial strains and identifying 16S rDNA sequences have been isolated from activated wastewater sludge. The 16S rDNA sequences are diagnostic for organisms which are key to the health of...
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7125712 |
Bovine immunodeficiency virus (BIV) based vectors
This invention pertains to BIV constructs encompassing BIV combination vectors, BIV vectors and BIV packaging vectors and particularly the invention pertains to a three vector system comprising: a)...
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7125981 |
Nucleic acid fragments for the identification of bacteria in industrial wastewater bioreactors
Unique bacterial strains and identifying 16S rDNA sequences have been isolated from activated wastewater sludge. The 16S rDNA sequences are diagnostic for organisms which are key to the health of...
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7122721 |
Plant gene expression under the control of constitutive plant V-ATPase promoters
To express selection genes and resistance genes, it would be desirable to have available plant constitutive promoters which has a strong uniform constitutive activity in as many plant tissues or...
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7122527 |
Use of antisense oligonucleotides to inhibit the expression of human Akt-1
New antisense oligonucleotide compounds inhibit expression of Akt-1 and also induce cytotoxicity in several cancer cell lines.
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7122180 |
DNA vectors containing mutated HIV proviruses
The present invention pertains to mutated, non-infectious HIV viral particles, vectors for production of such particles and vaccines employing such vectors. The non-infectious particles are...
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7122341 |
Engineering of metabolic control
The invention features a method of producing heterologous molecules in cells under the regulatory control of a metabolite and metabolic flux. The method can enhance the synthesis of heterologous...
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7122658 |
Seed-preferred regulatory elements and uses thereof
The present invention provides compositions and methods for regulating expression of isolated nucleotide sequences in a plant. The compositions are novel nucleic acid sequences for seed-preferred...
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7122354 |
Nucleic acid encoding a chimeric polypeptide
DNA molecules comprising a sequence encoding the signal peptide of hGH linked to a heterologous protein and related cells, methods and fusion proteins.
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RE39351 |
High level of expression of INGAP in bacterial and eukaryotic cells
Removal of the nucleotide sequence encoding the signal peptide from the INGAP coding sequence allows cultured cells to express substantial amounts of INGAP activity. Previous attempts have provided...
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7119251 |
Basal endosperm transfer cell layer (BELT) specific genes
Described are nucleic acid molecules encoding basal endosperm transfer cell layer (BETL) specific proteins as well as regulatory sequences which naturally regulate the expression of such nucleic...
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7119255 |
Promoter from maize prolamin seed storage protein and uses thereof
Provided is a nucleotide sequence of a promoter from a gene encoding a 55 kDa maize prolamin family protein. Also provided are methods that utilize the 55 kDa maize prolamin family gene promoter to...
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7119193 |
Identification of new small RNAs and ORFs of E. coli as mediators of cell and intercell regulation
The invention relates to new small RNAs and ORFs of E. coli as mediators of cell and intercell regulation.
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7119192 |
Stress-induced promoter derived from rice
The invention relates to an isolated stress-induced promoter which effectively functions in monocotyledonous plants such as rice, and of environmental stress tolerant plants using the promoter.
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7119184 |
Oligonucleotides having A-DNA form and B-DNA form conformational geometry
Modified oligonucleotides containing both A-form conformation geometry and B-from conformation geometry nucleotides are disclosed. The B-form geometry allows the oligonucleotide to serve as...
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7119250 |
Plant centromere compositions
The present invention provides for the nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and minichromosomes which can serve...
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7115793 |
Isolation and identification of transcription control elements associated with mouse eosinophil peroxidase expression
The present invention relates to novel transcription control elements derived from a mouse eosinophil peroxidase gene. Such transcription control elements may comprise isolated polynucleotides,...
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