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7189542 |
Drosophila clipped FRT (cFRT) chromosome insensitive to P transposase, generating method thereof, and application thereof
A method for generating a Drosophila clipped FRT (cFRT) chromosome is provided, wherein the chromosome is insensitive to a P transposase but remains functional to a yeast site-specific flippase...
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7186698 |
Spatial and temporal control of gene expression using a heat shock protein promoter in combination with local heat
The invention provides methods for using local heat to control gene expression. The heat shock protein (hsp) gene promoter is recombined with a selected therapeutic gene and expressed in selected...
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7186821 |
Rice sucrose transporter gene promoter
The present invention provides DNA having the promoter activity of an OsSUT1 gene, as well as a transgenic plant and others capable of expressing a desired foreign gene specifically in the vascular...
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7186815 |
Method of isolating secretion signals in lactic acid bacteria and novel secretion signals isolated from Lactococcus lactis
A method of identifying nucleotide sequences coding for signal peptides in lactic acid bacteria, using a DNA molecule comprising a transposon including a promoterless reporter gene from which DNA...
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7183047 |
Reporter gene construct for the detection of HIV Rev and HIV Tat
The present invention relates to a reporter gene construct for the detection of the HIV Rev and HIV Tat proteins. Furthermore, the invention relates to a functionality test method for Rev and Rev...
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7183079 |
Compositions and methods for enhancing disease resistance in fish
Compositions and methods for conferring enhanced disease resistance in a fish are provided. Compositions include novel recombinant constructs that induce transgenic expression of anti-pathogenic...
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7183262 |
Method for selective expression of therapeutic genes by hyperthermia
A method for controlling in vivo heat-inducible gene expression for provision of therapeutic polypeptide. The method includes the steps of: (a) providing a construct comprising a polynucleotide...
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7183109 |
Embryo preferred promoter and method of using same
A regulatory region is shown, a nucleotide sequence of approximately 3kb which provides improved seed preferred, and particularly embryo preferred expression in plants. Methods of use are also...
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7179960 |
Seed-associated promoter sequences
Plant promoters that exhibit seed-associated expression are described, including bi-directional promoters capable of directing seed-associated expression in either orientation.
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7179457 |
Modified nodavirus RNA for gene delivery
The invention provides a nodavirus RNA1 molecule modified to include a heterologous insertion which is downstream of its replicase ORF and, preferably, its B2 ORF. The insertion preferably...
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7179901 |
Renal regulatory elements and methods of use thereof
Disclosed are cis-acting regulatory elements from a KIM-1 gene. The elements can be used to direct the expression of operably linked sequences in renal tissue.
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7179903 |
Liver specific transcriptional enhancer
Recombinant lentiviruses and transfer vectors for transgene delivery as well as methods for gene therapy using such vectors are disclosed. The invention provides a third generation lentiviral...
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7179902 |
Use of regulatory sequences in transgenic plants
The present invention provides DNA sequences that function as 3′ untranslated regions (3′UTR) in plants. The 3′UTR's stabilize associated recombinant transcripts such that expression is...
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7179904 |
Promoter, promoter control elements, and combinations, and uses thereof
The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the...
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7179595 |
Compositions and methods for generating antigen-binding units
The present invention provides non-single-chain antigen-binding units that is stabilized by leucine zipper sequences. The experimental design is particularly useful for generating and screening for...
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7179959 |
Temporal seed promoters for expressing genes in plants
The present invention relates to the field of plant genetic engineering. More specifically, the present invention relates to seed specific gene expression during a defined period of embryogenesis....
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7176300 |
Avian lysozyme promoter
The invention provides for lysozyme gene expression control regions which may include a 5′ matrix attachment region; an intrinsically curved region of DNA; a transcription enhancer; a negative...
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7176301 |
Nitrate inducible promoter
A promoter comprising any one selected from the group consisting of the nucleotide sequence of SEQ ID No: 7, the nucleotide sequence of SEQ ID No: 8, the nucleotide sequence of SEQ ID No: 9, the...
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7176355 |
Plastid rRNA operon promoter elements for construction of chimeric promoters for transgene expression
Prrn promoter elements for enhancing expression of heterologous molecules, including RNA and proteins in the plastids of higher plants are disclosed.
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7176347 |
Vegetative growth specific promoter and transgenic plant obtained with the same
DNA having promoter activity for expressing an exogenous gene specifically in vegetative growth tissue (particularly, stems and/or leaves) is provided. The DNA is a rice OsGA3ox2 gene promoter...
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7173120 |
Regulatory sequences for regulation of gene expression in plants and other organisms, and compositions, products and methods related thereto
The invention relates to regulatory sequences that regulate gene expression in the mesocarp and/or senescent leaves of certain plants. In certain embodiments, the invention is directed to abundant...
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7173166 |
DNA sequence for root preferred gene expression in plants
Expression of DNA sequences in a preferred manner in the roots of a plant is often desirable. For instance improved resistance to soil-borne pathogens may be attained by expression of a pathogen...
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7173121 |
Promoter, promoter control elements, and combinations, and uses thereof
The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the...
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7173115 |
Stra6 polypeptides
The present invention is directed to novel polypeptides having sequence similarity to Stra6, a murine retinoic acid responsive protein, and to nucleic acid molecules encoding those polypeptides....
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7169967 |
Globulin-1 promoter from maize and method of using same
A globulin-1 regulatory region is shown, a nucleotide sequence of approximately 3 kb which provides improved seed preferred, and particularly embryo preferred expression in plants. Methods of use...
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7169968 |
Elongase promoters
The present invention relates to the use of recombinant DNA technology in the modification of plant oils. In particular, the invention relates to the identification of novel promoter sequences of...
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7169894 |
Methods and compositions for reverse translation
A process is disclosed by which a polynucleotide is directly synthesized from the peptide or protein that it encodes without the need for sequencing (or sequence analysis) of the peptide or...
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7169915 |
Promoter, promoter control elements, and combinations, and uses thereof
The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the...
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7169603 |
α-MSH related compounds and methods of use
The invention provides polypeptides containing α-MSH that can be used to treat diseases characterized by inflammation and/or autoimmunity. Also included in the invention are α-MSH analogs and...
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7166770 |
Cestrum yellow leaf curling virus promoters
This invention describes novel DNA sequences that function as promoters of transcription of associated nucleotide sequences. More specifically, this invention describes DNA sequences conferring...
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7166446 |
Method for expression of heterologous proteins in yeast
Compositions and methods for expression of heterologous mammalian proteins and their secretion in the biologically active mature form using a yeast host cell as the expression system are provided....
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7166430 |
Sequence of the tropheryma whippelii bacteria rpoB gene and oligonucleotide for molecular diagnosis of whipple's disease
The invention concerns the total sequence of the Tropheryma whippelii bacteria rpoB gene, characterized in that it consists of the nucleotide sequence SEQ ID no. °9, and the nucleotide sequences...
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7166465 |
Constitutive promoter from Arabidopsis
The present invention is directed to a promoter derivable from an Arabidopsis ENDO gene. Nucleic acid constructs, vectors, plant cells and transgenic plants comprising the promoter are also...
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7163927 |
Antisense modulation of kinesin-like 1 expression
Antisense compounds, compositions and methods are provided for modulating the expression of kinesin-like 1. The compositions comprise antisense compounds, particularly antisense oligonucleotides,...
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7161060 |
Transgenic mice comprising a genomic human tau transgene
The invention provides transgenic mice comprising tau transgenes, and methods of preparing and using the transgenic mice. For example, the invention provides a transgenic mouse, the genome of the...
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7160682 |
Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell
The present invention provides for transposon vectors encoding expression control region-traps and gene-traps. Also provided are dicistronic vectors. Certain embodiments of the invention contain...
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7157571 |
Hepatoma specific chimeric regulatory sequence
The present invention relates to a chimeric regulatory sequence with hepatoma cell specificity. The chimeric regulatory sequence includes a proximal regulatory sequence and a distal enhancer of...
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7157436 |
Therapeutically useful synthetic oligonucleotides
The present invention provides a composition and method comprising a 2–20 base 3′-OH, 5′-OH synthetic oligonucleotide (sequence) selected from the group consisting of (G x T y ) n , (T y G x...
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7157570 |
Human ribonucleotide reductase M2 subunit
An isolated nucleic acid containing a human ribonucleotide reductase M2 subunit promoter sequence or genomic sequence. Also disclosed are methods of determining whether a subject is suffering from...
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7157272 |
Constructs for gene expression analysis
The present invention relates generally to constructs and their use in gene expression or gene regulation assays. More particularly, the present invention provides expression vectors and/or...
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7154023 |
Transgenic plants with altered levels of phenolic compounds
Methods for altering levels in plants of one or more phenolic compounds that are intermediates or final products of the plant phenylpropanoid pathway are provided. One method comprises transforming...
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7154024 |
Male tissue-preferred regulatory sequences of Ms45 gene and method of using same
The present invention relates to isolated male tissue-preferred regulatory sequences from Ms45 gene. The invention also relates to the use of Ms45 gene male tissue-preferred regulatory sequences in...
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7153953 |
Leaf specific gene promoter of coffee
The present invention relates to a nucleotide sequence derived form coffee leaves that may be used as a promoter for an inducible expression of genes in plants. In particular, the present invention...
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7153670 |
Hyaluronan-binding proteins and encoding genes
The present invention relates to full-length WF-HABP, WF-HABP, OE-HABP, and BM-HABP, members of the hyaluronan receptor family. The invention provides isolated nucleic acid molecules encoding human...
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7151204 |
Maize chloroplast aldolase promoter compositions and methods for use thereof
The current invention provides the promoter of the Zea mays nuclear gene encoding chloroplast-localized fructose-1,6-bisphosphate (F16BP) aldolase. Compositions comprising this sequence are...
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7151205 |
Plant male tissue-preferred promotor, regulatory regions and methods of use in mediating plant male fertility
Nucleotide sequences which are male tissue-preferred promoters and male tissue-preferred regulatory regions are disclosed, as are sequences essential to initiating transcription of select genes....
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7148064 |
Method for reducing phytate in canola meal using genetic manipulation involving myo-inositol 1-phospathe synthase gene
A plant, multicellular fragment of said plant or seed of said plant transformed with a nucleotide sequence of SEQ ID NO 1 or an allelic variant or a fragment thereof or a genetic equivalent thereof...
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7148342 |
Compositions and methods for sirna inhibition of angiogenesis
RNA interference using small interfering RNAs which are specific for the vascular endothelial growth factor (VEGF) gene and the VEGF receptor genes Flt-1 and Flk-1/KDR inhibit expression of these...
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7148204 |
Antisense modulation of bcl-x expression
Compositions and methods are provided for modulating the expression of bcl-x. Antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding bcl-x are preferred....
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7148203 |
Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell
This invention relates to a system for introducing nucleic acid into the DNA of a cell. The system includes the use of a member of the SB family of transposases (SB) or nucleic acid encoding the...
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