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7622637 |
Seed-preferred regulatory elements
The present invention provides compositions and methods for regulating expression of nucleotide sequences in a plant. Compositions are novel nucleotide sequences for a tissue preferred promoter...
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7622636 |
Dehydrin gene from Avicennia marina responsible for conferring salt tolerance in plants
The present invention relates to a method of producing salt-stress tolerant plants by transforming the plants with an isolated nucleic acid sequences encoding a dehydrin (DHN) protein. The...
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7622573 |
Expression control elements from the lemnaceae family
Compositions and methods for regulating expression of nucleotide sequences of interest in a plant are provided. Compositions include novel nucleic acid molecules, and variants and fragments...
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7622455 |
Methods for slowing familial ALS disease progression
Methods for slowing disease progression in an individual suffering from familial ALS are provided. Also provided are methods of increasing the survival time of an individual suffering from familial...
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7622300 |
Trans-lentiviral vector particles and transduction of eukaryotic cells therewith
Trans-lentiviral gene transfer vectors, vector systems, vector particles, and methods for transduction of primary nondividing cells using the same, are described. Further described are...
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7620502 |
Methods for identifying sets of oligonucleotides for use in an in vitro recombination procedure
In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators are used to identify sets of oligonucleotides for in vitro recombination.
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7619135 |
Seed-specific promoter from the rice glutelin GluB-4 gene and uses thereof
An objective of the present invention is to provide promoters having seed-specific promoter activity, and methods of expressing foreign proteins in seeds. In particular, a seed specific promoter...
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7618947 |
Modulation of HIF-1 beta expression
Compounds, compositions and methods are provided for modulating the expression of HIF1-beta. The compositions comprise oligonucleotides, targeted to nucleic acid encoding HIF1-beta. Methods of...
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7618778 |
Producing, cataloging and classifying sequence tags
The described method provides, methods, and kits to produce, identify, catalog and classify a comprehensive collection of nucleic acid targets produced from a nucleic acid sample. The method,...
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7615680 |
Temporal seed promoters for expressing genes in plants
The present invention relates to the field of plant genetic engineering. More specifically, the present invention relates to seed specific gene expression during a defined period of embryogenesis....
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7615676 |
Transgenic screen and method for screening modulators of brain-derived neurotrophic factor (BDNF) production
A transgenic screen and method for screening biological and chemical test substances or molecules for their ability to influence or modulate the production of BDNF in cells, includes a fusion gene...
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7615624 |
Arabidopsis derived promoters for regulation of plant expression
The invention provides a method to identify a plurality of plant promoters having specified characteristics and promoters identified by the method. The plant genus from which at least some of the...
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7615540 |
Formulations comprising antisense nucleotides to connexins
A therapeutic and/or cosmetic formulation comprising at least one anti-sense polynucleotide to a connexin protein together with a pharmaceutically acceptable carrier or vehicle is useful in site...
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7612252 |
Homeotic genes and proteins, uses thereof
The homeotic gene AGL42 in Arabidopsis has been cloned and characterized and is presented herein, both alone and in association with expression control sequences and in vectors which may be used...
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7608706 |
siRNA targeting ras-related nuclear protein
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
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7608451 |
Gene regulation in transgenic animals using a transposon-based vector
Administration of modified transposon-based vectors has been used to achieve stable incorporation of exogenous genes into animals. These transgenic animals produce transgenic progeny. Further,...
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7605252 |
siRNA targeting kinase insert domain receptor (KDR)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
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RE40940 |
Yeast promoter and use thereof
The present invention concerns DNA sequences from the K. lactis PGK gene having transcriptional promoter activity. to expression vectors comprising these sequences and to their use for the...
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7601885 |
Transgenic plant comprising a cassava vein mosaic virus promoter and a heterologous nucleic acid sequence
The invention relates to compositions and methods useful for the production of transgenic plants. In particular, the invention relates to cassava vein mosaic virus (CsVMV) promoter sequences and...
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7601700 |
Modulation of eIF4E expression
Oligomeric compounds, compositions and methods are provided for modulating the expression of eIF4E. The antisense compounds may be single- or double-stranded and are targeted to nucleic acid...
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7598370 |
siRNA targeting polo-like kinase-1 (PLK-1)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
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7598368 |
COX5c-1 gene intron for increasing expression level in cassettes, plant cells and transgenic plants
An isolated DNA molecule for enhancing gene expression of a coding sequence, fragment, genetic variant, cassette, vector, cell, plant and seed containing said molecule, wherein the molecule...
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7598367 |
Early light-induced protein promoters
The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the...
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7598366 |
TaBV transcriptional control elements, chimeric constructs and uses therefor
This invention discloses a constitutive promoter from the Taro bacilliform virus (TaBV) for expression of foreign or endogenous coding sequences in plants, including dicotyledonous and...
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7595388 |
siRNA targeting EPH receptor A3 (EPHA3)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
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7595384 |
Seed-specific gene promoter from the rice 10 KDa prolaminin gene and uses thereof
An objective of the present invention is to provide a promoter from the rice 10 kDa Prolaminin gene having seed-specific promoter activity, and methods of expressing foreign proteins in seeds. The...
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7595301 |
Staple type oligonucleotide and drug comprising the same
Conventional oligonucleotides are opened at both ends and thereby unstable. Their stability against catabolic enzymes is increased by phosphorothioate modification, but such phosphorothioate causes...
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7595164 |
Compositions and methods to detect Candida albicans nucleic acid
Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, capture probes for sample preparation, and detection probes specific for ...
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7592444 |
siRNA targeting myeloid cell leukemia sequence 1
Efficient sequence specific gene silencing of myeloid cell leukemia sequence 1 is possible through the use of siRNA technology. By selecting particular siRNAs directed to myeloid cell leukemia...
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7592324 |
RNAi-mediated inhibition of ocular targets
RNA interference is provided for inhibition of ocular hypertension target mRNA expression for lowering elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension....
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7592161 |
Methods for analyzing the insertion capabilities of modified group II introns
The present invention provides a system and methods for analyzing the function of nucleotide integrases and modified group II introns. The system comprises a donor plasmid comprising a wild-type or...
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7589254 |
Transgenic expression cassettes for expressing nucleic acid sequences in sink tissues of plants that store carbohydrate
The invention relates to methods for the directed, transgenic expression of nucleic acid sequences in the carbohydrate-storing sink tissues of plants using transgenic expression cassettes which...
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7589188 |
Actin regulatory elements for use in plants
The present invention provides polynucleotide molecules isolated from Oryza sativa and Zea mays and useful for expressing transgenes in plants. The present invention also provides expression...
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7589074 |
Methods and compositions for treatment of inflammatory disease using cadherin-11 modulating agents
A method for treating inflammatory joint diseases by inhibiting cadherin-11 mediated cellular function using a cadherin-11 modulating agent is provided. Also provided are screening assays for...
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7588941 |
Dispersion of carbon nanotubes by nucleic acids
Nucleic acid molecules in a stabilized solution such as single stranded DNA and RNA were able to disperse high concentration of bundled carbon nanotubes into aqueous solution.
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7585963 |
Chicken ovalbumin nucleotide sequence
The present invention provides isolated and recombinant avian nucleic acid molecules comprising at least one avian MAR and an avian nucleic acid sequence encoding an ovalbumin transcriptional...
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7585962 |
Multimerized enhancer domains for cell-specific expression
The invention features an enhancer cassette and methods of its use. The enhancer cassette has the formula [X−Y] n , wherein each X is independently a cell type-specific enhancer element; Y is...
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7585498 |
Regulation of adenovirus DNA packaging by IPTG
The present invention relates to recombinant Adenoviruses (Ad) which function as helper viruses to gutted Ad viruses lacking viral coding sequences. The recombinant Ad of the present invention...
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7582807 |
Regulation of gene expression using chromatin remodelling factors
The invention provides a method to regulate expression of a gene of interest in a plant comprising, introducing into the plant a first nucleotide sequence comprising, the gene of interest...
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7582747 |
siRNA targeting inner centromere protein antigens (INCENP)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
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7582746 |
siRNA targeting complement component 3 (C3)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
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7579516 |
Promoters functional in plant plastids
The present invention relates to isolated nucleic acid molecule comprising the untranslated region of SEQ ID NO: 1, 2 or 3. The invention also relates to chimeric genes comprising SEQ ID NO: 2...
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7579330 |
Methods of treating various cancers using melanoma differentiation associated protein-7
This invention provides a method for reversing the cancerous phenotype of a cancer cell by introducing a nucleic acid having the melanoma differentiation associated gene (mda-7) into the cell under...
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7579329 |
P450RAI-2 (P450 cytochrome 26B), encoding nucleic acid molecules and methods and uses thereof
The present invention provides a novel all-trans-RA inducible all-trans-RA metabolizing cytochrome P450, P450RAI-2, that is predominantly expressed in the brain, cerebellum in particular. It is...
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7579327 |
Promoters exhibiting endothelial cell specificity and methods of using same
An isolated polynucleotide functional as a promoter in eukaryotic cells is disclosed. The isolated polynucleotide includes an endothelial specific enhancer element as detailed herein. Further...
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7579326 |
Gene switch systems employing regulators with decreased dimerization
Disclosed is a novel inducible expression system characterized by undetectable biological effect in the absence of an inducer, but which exhibits efficient inducibility in the presence of an inducer.
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7579168 |
Human Dickkopf-related nucleic acid molecules
Novel Dkk and Dkk-related polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length Dkk and Dkk-related proteins, the invention further provides...
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7576196 |
siRNA targeting transducin (beta)-like 3 (TBL3)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
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7576195 |
Endosperm-specific plant promoter for cultivated plants
The invention provides an endosperm-specific plant promoter, as well as vectors, plant cells, and plant tissues comprising the endosperm-specific promoter. The invention also provides methods of...
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7575918 |
Tissue-specific and pathogen-specific ribozymes
The present invention relates to the discovery, identification and characterization of toxic agents which are lethal to pathogens and methods for targeting such toxic agents to a pathogen or...
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