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7575913 |
Chlamydia trachomatis genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection
The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia trachomatis , such as cellular envelope polypeptides, which are secreted or...
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7572602 |
Nucleic acid encoding endolysin fusion protein
The invention concerns a recombinant nucleic acid molecule encoding an antimicrobial fusion peptidoglycan endopeptidase. The recombinant nucleic acid molecule according to the invention is formed...
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7572903 |
Method of regulation of bacterial persister status
In one embodiment, the present invention is a method of controlling persister status in a bacterial cell population comprising the step of modulating the expression of native chromosomal sequences...
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7569748 |
Nucleic acid encoding an insecticidal protein toxin from photorhabdus
Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens ) have been found in mammalian clinical samples and as a...
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7569682 |
Brachyspira hyodysenteriae vaccine
The present invention relates to nucleic acid sequences encoding a 30 kD Brachyspira hyodysenteriae lipoprotein and to parts of such nucleic acid sequences that encode an immunogenic fragment of...
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7569683 |
UspA2 nucleic acid of Moraxella catarrhalis
The present invention discloses the existence of two novel proteins UspA1 and UspA2, and their respective genes uspA1 and uspA2. Each protein encompasses a region that is conserved between the two...
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7566818 |
Second TC complex from xenorhabdus
The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins...
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7566459 |
Modified mycobacterium tuberculosis strains and uses thereof
The present invention features modified Mycobacterium tuberculosis strains which lack a functional lspA gene, and vaccine formulations comprising the same. In many embodiments, a modified ...
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7563883 |
Recombinant P. falciparum merozoite protein-142 vaccine
In this application is described the expression and purification of a recombinant Plasmodium falciparum (FVO) MSP-1 42 . The method of the present invention produces a highly purified protein...
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7563878 |
Bacterial phytases and method for producing same
The invention concerns novel bacterial phytases, and their respective production methods. More particularly, the invention concerns novel phytases derived from bacteria of genus Acidocella , and...
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7560234 |
Detection of ochratoxin A producing fungi
Nucleotide or amino acid sequences that may be used in the detection and/or identification for an ochratoxigenic fungus or in the construction of an atoxigenic strain of an ochratoxigenis fungus....
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7557202 |
DNA fragments containing gene having function relating to autonomous proliferation of plasmid
Provided are a DNA fragment containing a gene relating the autonomous replication of a plasmid, and a DNA fragment containing a gene relating to the autonomous replication of a plasmid wherein a...
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7556958 |
Enzyme derived from thermophilic organisms that functions as a chromosomal replicase, and preparation and uses thereof
A DNA Polymerase has been identified in a thermophile that functions as a chromosomal replicase. The specific enzyme is a holoenzyme III that has been identified in Thermus thermophilus , and...
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7557262 |
Self processing plants and plant parts
The invention provides polynucleotides, preferably synthetic polynucleotides, which encode processing enzymes that are optimized for expression in plants. The polynucleotides encode mesophilic,...
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7556810 |
Compositions and methods to control angiogenesis with cupredoxins
The present invention relates to compositions comprising cupredoxins, and their use to inhibit angiogenesis in mammalian cells, tissues, and animals, and particularly the angiogenesis that...
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7557200 |
Superior molecular vaccine based on self-replicating RNA, suicidal DNA or naked DNA vector, that links antigen with polypeptide that promotes antigen presentation
Improved molecular vaccines comprise nucleic acid vectors that encode a fusion polypeptide that includes polypeptide or peptide physically linked to an antigen. The linked polypeptide is one that...
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7556807 |
Signal peptides, nucleic acid molecules and methods for treatment of caries
Peptide analogues of S. mutans CSP peptide which inhibit biofilm formation, uses thereof in the preparation of pharmaceutical compositions, antimicrobial compositions and uses thereof in the...
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7556959 |
Polynucleotide encoding a polypeptide having a larvae growth inhibiting or insecticidal effect on Scarabaeidae insects
Through screening using an antibody to a polypeptide that constitutes a parasporal body in sporangia of Bacillus popilliae and has a larvae growth inhibiting or insecticidal effect on a ...
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7553493 |
Chlamydia flagellar protein antigen
The present invention provides purified and isolated polynucleotide molecules that encode Chlamydia polypeptides which can be used in methods to prevent, treat, and diagnose Chlamydia ...
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7550576 |
Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor
Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides,...
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7541447 |
Process for the preparation of an improved Brucella strain plasmid to develop the strain and the vaccine comprising the said strain
A Brucella bacterium is modified by partial or complete deletion of the pgm gene, rendering the bacterium incapable of synthesizing a key enzyme in the metabolism of bacterial sugars. A live...
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7541170 |
Nucleic acid modifying enzymes
This invention provides for an improved generation of novel nucleic acid modifying enzymes. The improvement is the fusion of a sequence-non-specific nucleic-acid-binding domain to the enzyme in a...
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7538206 |
Comparative mycobacterial geneomics as a tool for identifying targets for the diagnosis, prophylaxis or treatment of mycobacterioses
The present invention is directed to a method of selection of purified nucleotidic sequences or polynucleotides encoding proteins or part of proteins carrying at least an essential function for the...
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7538208 |
Type III secretion pathway in Aeromonas salmonicida, and uses therefor
Disclosed is a newly identified and characterized type III secretion system in Aeromonas salmonicida . The invention also encompasses the use of components of the novel secretion system in...
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7538209 |
Lactobacillus acidophillus nucleic acid sequences encoding cell surface protein homologues and uses therefore
Cell wall, cell surface and secreted protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, cell wall, cell surface...
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7538207 |
Polyepitope carrier protein
The invention relates to polyepitope carrier proteins that comprise at least five CD4+T cell epitopes, for conjugation to capsular polysaccharides. The carrier proteins are use useful as components...
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7534445 |
Chlamydia protein, sequence and uses thereof
A high molecular weight (“HMW”) protein of chlamydia , the amino acid sequence thereof, and antibodies that specifically bind the HMW protein are disclosed as well as the nucleic acid sequence...
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7534876 |
Lactobacillus acidophilus nucleic acid sequences encoding cell surface protein homologues and uses therefore
Cell wall, cell surface and secreted protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, cell wall, cell surface...
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7531647 |
Lentiviral vectors for site-specific gene insertion
Murine leukemia virus (MLV) and lentivirus vectors have been used previously to deliver genes to hematopoietic stem cells (HSCs) in human gene therapy trials. However, these vectors integrate...
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7528242 |
Methods and compositions comprising Renilla GFP
The invention relates to methods and compositions utilizing Renilla green fluorescent proteins (rGFP), and Ptilosarcus green fluorescent proteins (pGFP). In particular, the invention relates to...
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7524657 |
Alleles of the sigA gene from coryneform bacteria
The invention relates to alleles of the sigA gene from coryneform bacteria which code for sigma factors A and a process for the fermentative preparation of L-lysine using bacteria which contain...
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7524675 |
Pharmaceutical use of alpha antigen or alpha antigen gene
The α antigen-encoding gene and the α antigen protein suppress the production of interleukin-4 etc., improve the Th2 type cytokine-dominant state, and furthermore inhibit various conditions of...
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7525014 |
Disease-resistant plants and method of constructing the same
It is the object of the present invention to provide disease-resistant plants which have been transformed to cause an effective defense reaction, and methods for producing the same. The present...
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7521549 |
Compounds
The invention provides BASB041, 43, 44 and 48 polypeptides and polynucleotides encoding BASB041, 43, 44 and 48 polypeptides and methods for producing such polypeptides by recombinant techniques....
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7521221 |
Staphylococcus aureus strain CYL1892
This disclosure presents embodiments of novel strains of Staphylococcus aureus that through genetic engineering produce type 5 capsular polysaccharide at greater levels than Staphylococcus...
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7521595 |
Repressor-mediated regulation system for control of gene expression in plants
The invention provides a method for selectively controlling the transcription of a gene of interest, comprising producing one or more plants that express either a first, a second, or both the first...
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7517684 |
Nucleic acid and amino acid sequences relating to Pseudomonas aeruginosa for diagnostics and therapeutics
The invention provides isolated polypeptide and nucleic acid sequences derived from Pseudomonas aeruginosa that are useful in diagnosis and therapy of pathological conditions; antibodies against...
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7517956 |
Xenorhabdus TC proteins and genes for pest control
The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins...
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7514547 |
Helicobacter felis vaccine
The present invention relates to novel Helicobacter felis urease subunit polypeptides and to nucleic acid sequences encoding these subunit polypeptides, to DNA fragments and recombinant DNA...
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7514089 |
Genetically modified tumor-targeted bacteria with reduced virulence
The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The present invention...
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7510854 |
Corynebacterium glutamicum genes encoding metabolic pathway proteins
Isolated nucleic acid molecules, designated MP nucleic acid molecules, which encode novel MP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic...
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7504239 |
Method of differentiating beer yeast
The method of differentiating beer yeast of the invention is a method which comprises a first step of synthesizing a primer capable of amplifying the linker portion between a base sequence (A) and...
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7504111 |
Gonococcal proteins and nucleic acids
The invention provides proteins from gonococcus ( Neisseria gonorrhoeae ), including amino acid sequences, the corresponding nucleotide sequences, expression data, and serological data. The...
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7494774 |
Assay and compositions for detection of Bacillus anthracis nucleic acid
The invention includes compositions and methods of detection of Bacillus anthracis that use oligonucleotide probes specific for genetic material contained in the pXO1 and pXO2 plasmids in nucleic...
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7495091 |
Polynucleotides encoding novel proteins in enteroaggregative Escherichia coli (EAEC) useful for diagnosis and therapy of EAEC infections
Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of...
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7491798 |
Scytovirins and related conjugates, fusion proteins, nucleic acids, vectors, host cells, compositions, antibodies and methods of using scytovirins
An isolated or purified antiviral protein of SEQ ID NO: 1, nucleic acids encoding the antiviral protein, cells comprising the nucleic acids, and methods of inhibiting viral infection comprising...
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7491511 |
Fungal antigens and process for producing the same
There can be provided a fungal antigen which is an insoluble fraction obtainable from fungal cells of which cell wall has been substantially removed or at least partially removed; a process for...
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7491402 |
Superantigens SMEZ-2, SPE-G, SPE-H and SPE-J and uses thereof
The invention provides superantigens SMEZ-2, SPE-G, SPE-H and SPE-J, as well as polynucleotides which encode them. Such superantigens have, inter alia, diagnostic and therapeutic application.
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7485306 |
Lutzomyia longipalpis polypeptides and methods of use
Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides...
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7482151 |
Method of using ammonia-oxidizing bacteria
Described herein are novel ammonia-oxidizing bacteria as well as isolated nucleotide sequences representative of 16S rDNA of these ammonia-oxidizing bacteria. Particular bacteria of the present...
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