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6808914 |
Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene
The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the...
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6808711 |
Immunologically active proteins from Borrelia burgdorferi, nucleic acids which encode them, and their use in test kits and as vaccines
The present invention relates to immunologically active proteins from Borrelia burgdorferi which are present in a form which is free of other proteins derived from Borrelia burgdorferi and...
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6806068 |
Nucleotide sequences which encode the pfk gene
The present invention is directed to nucleotide sequences coding for phosphofructokinase which have been derived from Corynebacterium glutamicum . The invention also encompasses methods for...
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6806065 |
Rickettsia felis outer membrane protein
The present invention is directed to isolated nucleic acid molecules encoding Rickettsia felis outer membrane proteins ( R. felis omp). Expression vectors and host cells comprising the nucleic...
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6803230 |
Phagemid vectors
Phagemid vectors containing a sequence of features between a Col E1 origin and an f1 origin are useful for display of polypeptides or proteins, including antibody libraries.
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6803231 |
Method of delivering antigens for vaccination with a live vector
The present invention provides a mutant C. fetus strain in which one or more sapA homologs are altered by an inserted DNA cassette so that the encoded S-layer proteins represent a chimera between...
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6803043 |
Basbo27 proteins and genes from moraxella catarrhalis, antigens, antibodies, and uses
The invention provides BASB027 polypeptides and polynucleotides encoding BASB027 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
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6800442 |
Methods of selecting polynucleotides encoding antigens
The present invention relates to novel methods for the identification of antigens recognized by cytotoxic T cells (CTLs) and specific for human tumors, cancers, and infected cells, and the use of...
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6797466 |
Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii
The present application describes the complete 1.66-megabase pair genome sequence of an autotrophic archaeon, Methanococcus jannaschii , and its 58- and 16-kilobase pair extrachromosomal elements....
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6797273 |
Neisseria meningitidis antigen
The invention provides BASB053 polypeptides and polynucleotides encoding BASB053 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
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6797509 |
Nucleotide sequences which code for the tal gene
The invention is directed to DNA sequences from coryneform bacteria which encode a protein having transaldolase enzymatic activity. The invention also encompasses methods for the fermentative...
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6797490 |
Formicidae (ant) control using Bacillus thuringiensis toxin
A composition and method for killing fire ants is disclosed that includes the purified and activated Cry toxin from a novel strain of Bacillus thuringiensis , wherein the water soluble, partially...
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6794177 |
Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction
A purified DNA polymerase exhibiting reverse transcriptase activity in the presence of magnesium ions and/or manganese ions having reduced or no 5′-3′-exonuclease activity and substantially no...
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6793927 |
Construction of Pasteurella haemolytica vaccines
Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica . A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the...
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6790937 |
Recombinant scFV antibodies specific to Eimeria spp. responsible for coccidiosis
The present invention relates to (a) variable regions of heavy and light chains of an antibody specific to a surface antigen in sporozoite of Eimeria spp.; (b) a recombinant scFV (single chain...
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6791008 |
Use of a class of enzymes and their encoding genes to increase the oil content in transgenic organisms
The present invention relates to the use of a novel enzyme and its encoding gene for transformation. More specifically, the invention relates to the use of a gene encoding an enzyme with...
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6790630 |
DNA and protein from Dirofilaria immitis
In accordance with the present invention, a 31-33 kDa glycoprotein of D. immitis (DiT33) is provided which represents another member of the family of putative pepsin inhibitors. Other known...
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6787142 |
Mutant human hepatitis B viral strain and uses thereof
This invention provides an isolated strain of Hepatitis B virus designated Human Hepatitis B Virus Surface Antigen-‘S’-133 Oon Strain (Methionine to Threonine) which constituent viral genome is...
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6783930 |
Development of novel anti-microbial agents based on bacteriophage genomics
A method for identifying suitable targets for antibacterial agents based on identifying targets of bacteriophage-encoded proteins is described. Also described are compositions useful in the...
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6783967 |
Nucleotide sequences which code for the rpoB gene
The present invention relates to polynucleotides corresponding to the rpoB gene and which encode the β-subunit of RNA polymerase B, methods of producing L-amino acids, and methods of screening for...
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6780419 |
Basb029 polynucleotide(s) and polypeptides from neisseria meningitidis
The invention provides BASB029 polypeptides and polynucleotides encoding BASB029 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
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6777229 |
Plasmids from Corynebacterium glutamicum and use thereof
This invention relates to the mutually compatible plasmids pTET3 and pCRY4, isolated from the strain of Corynebacterium glutamicum deposited under DSM number 5616, wherein plasmid pTET3 is...
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6777235 |
Complementation trap
Methods and DNA constructs are provided for detection and manipulation of a target eukaryotic gene whose expression is restricted to certain tissues or specialized cell types. The methods include...
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6777215 |
Cyclomaltodextrin glucanotransferase variants
The present invention relates to variants of cyclomaltodextrin glucanotransferase of increased product specificity.
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6776993 |
Tuberculosis vaccine
The present invention relates to novel recombinant vaccines providing protective immunity against tuberculosis. Further, the present invention refers to novel recombinant nucleic acid molecules,...
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6773880 |
Streptococcus pneumoniale 37-kDa surface adhesion A protein
The invention provides a nucleic acid encoding the 37-kDa protein from Streptococcus pneumoniae . Also provided are isolated nucleic acids comprising a unique fragment of at least 10 nucleotides...
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6770284 |
Polypeptides and polynucleotides BASB040 from neisseria meningitidis and vaccine comprising said polypeptides and polynucleotides
The invention provides BASB040 polypeptides and polynticleotides from Neisseria meningitidis encoding BASB040 polypeptides and methods for producing such polypeptides by recombinant techniques....
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6770798 |
Nucleic acid sequences coding for thanatin and transformed plants containing them
The invention concerns a nucleic acid sequence coding for thanatin, a vector containing it for transforming a host, and plants and plant cells transformed by the nucleic acid.
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6770464 |
Methods for producing poly(hydroxy) fatty acids in bacteria
The present invention relates to a process for the production of poly (hydroxy fatty acids) as well as recombinant bacterial strains for carrying out the process. In addition, new poly(hydroxy...
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6770459 |
Immunogenic compounds
The invention provides BASB081 polypeptides and polynucleotides encoding BASB081 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
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6764823 |
Antimicrobial methods and materials
The present invention provides methods of identifying antimicrobial agents that target genes essential for the survival of Staphylococcus bacteria, including antimicrobial agents that interfere...
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6765127 |
Invertebrate intestinal mucin cDNA and related products and methods
The invention represents the disclosure of an insect intestinal mucin (IIM) protein. The IIM protein was been identified and cloned using Trichoplusia ni larva. The cDNA and amino acid sequences...
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6764834 |
BASB019 proteins and genes from Moraxella catarrhalis, antigens, antibodies, and uses
The invention provides BASB019 polypeptides and polynucleotides encoding BASB019 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
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6762046 |
Polypeptide having β-fructofuranosidase activity
A polypeptide having β-fructofuranosidase activity is obtained by the expression of a microbial gene, which polypeptide contains the amino acid sequences of SEQ ID NO:1 and SEQ ID NO:2 in whole or...
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6762295 |
Protective helicobacter antigens
Protective Helicobacter antigens, especially H. pylori antigens, and the use of these antigens for the treatment of or prevention of, gastroduodenal disease associated with H. pylori infection.
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6759575 |
Barstar gene
An improved barstar gene and improved barstar protein can be used to neutralize the activity of a barnase in eukaryotic cells, particular in plant cells. The improved barstar gene can be used to...
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6759213 |
Haemophilus adhesion proteins
The invention relates to novel Haemophilus adhesion proteins, nucleic acids, and antibodies.
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6759531 |
Kits ands compositions for the detection of haemobartonella
In broad terms, the present invention includes materials and methods useful to distinguish between and among species of a genus. The present methods utilize the differences in PCR amplicon sizes to...
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6759530 |
IBD-associated microbial nucleic acid molecules
The present invention provides nucleic acid and amino acid sequence of the novel I-1 and I-2 polypeptides, which are associated with human inflammatory bowel disease (IBD). Methods of diagnosing...
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6756493 |
Nucleic acid sequence and uses thereof
The invention discloses the Neisseria spp. NGSP polypeptide, polypeptides derived therefrom (NGSP-derived polypeptides), nucleotide sequences encoding said polypeptides, and antibodies that...
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6753177 |
P-glycoproteins and uses thereof
The invention pertains to dog P-glycoproteins and related P-glycoproteins which include dog-specific amino acids, as well as nucleic acids which encode those polypeptides. The present invention...
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6753149 |
Staphylococcus aureus genes and polypeptides
The present invention relates to novel genes from S. aureus and the polypeptides they encode. Also provided as are vectors, host cells, antibodies and recombinant methods for producing the same....
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6750020 |
Method for alteration detection
Methods are provided for detecting an alteration in a target nucleic acid. Methods of the invention are useful for detecting and identifying mutations that are indicative of disease or the...
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6746854 |
Nucleotide sequences encoding histidine kinase from corynebacterium glutamicum
This invention relates to novel polynucleotide sequences encoding the histidine kinase luminescence expression sensor (luxS) gene from Corynebaclerium glutamicum , probes to the novel...
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6743606 |
Processive sugar transferase
The invention relates to a protein which presents identical or different catalytically active domains of glycosyltransferases and has a processive action. In particular, the same protein is...
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6743616 |
Highly productive alpha-amylases
The invention relates to mutant α-amylases that may be produced at high yield from recombinant microorganisms.
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6737255 |
Mutant ilvH gene and method for producing L-valine
The present invention provides an isolated DNA molecule encoding a small subunit of acetohydroxy acid synthase isozyme III originating from Escherichia coli and mutants of Escherichia coli ...
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6737237 |
Antimicrobial agents, diagnostic reagents, and vaccines based on unique Apicomplexan parasite components
This invention relates uses of Toxoplasma gondii chorismate synthase, a component components of plant-like metabolic pathways not including psbA or PPi phosphofructokinase and not generally...
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6737063 |
FimH adhesin proteins and methods of use
The present invention provides bacterial immunogenic agents for administration to humans and non-human animals to stimulate an immune response. Also provided are methods for vaccination of...
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6737248 |
Staphylococcus aureus polynucleotides and sequences
The present invention provides polynucleotide sequences of the genome of Staphylococcus aureus , polypeptide sequences encoded by the polynucleotide sequences, corresponding polynucleotides and...
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