|
Match
|
Document |
Document Title |
|
|
7390894 |
Glutathione S-transferase sequence variants
Isolated GSTO2 nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as GSTO2 allozymes. Methods for determining if...
|
|
|
7390637 |
Keratinocyte derived interferon
The present invention relates to a novel KDI protein which is a member of the interferon family. In particular, isolated nucleic acid molecules are provided encoding a human interferon polypeptide,...
|
|
|
7388093 |
Gene for identifying individuals with familial dysautonomia
This invention relates to methods and compositions useful for detecting mutations which cause Familial Dysautonomia. Familial dysautonomia (FD; Riley-Day syndrome), an Ashkenazi Jewish disorder, is...
|
|
|
7388087 |
Enhancement of immune response to vaccine by interferon alpha
Exogenous cDNA capable of expressing interferon α activity, exogenous interferon α protein, inducers of endogenous interferon α protein activity, inducers of endogenous interferon β protein...
|
|
|
7388086 |
NPHS2 gene involved in the steroid-resistant nephrotic syndrome, protein encoded by said gene and diagnostic and therapeutic uses
The invention concerns a novel gene, called NPHS2 gene coding for a protein involved in the cortico-resistant nephrotic syndrome, and diagnostic and therapeutic uses of the novel identified...
|
|
|
7387885 |
Growth factor homolog zvegf3 polynucleotides
Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that...
|
|
|
7387780 |
Soluble interleukin-20 receptor
A soluble receptor to IL-20 having two polypeptide subunits, IL-20RA (formerly called ZcytoR7) and IL-20RB (formerly called DIRS1). The two subunits are preferably linked together. In one...
|
|
|
7385045 |
Canine B7-1 nucleic acid molecules
The present invention relates to B7 proteins; to B7 nucleic acid molecules, including those that encode such B7 proteins; to antibodies raised against such B7 proteins; and to therapeutic compounds...
|
|
|
7385044 |
Isolated peptides which bind to MHC Class II molecules, and uses thereof
Peptides which have an amino acid sequence identical to sequences found in tumor rejection antigen precursors, such as NY-ESO-1, and SSX-2, are disclosed. These peptides bind to MHC-Class II...
|
|
|
7384913 |
PT32 sperm protein, sperm c-Yes, oocyte cytoplasmic c-Yes, and uses thereof
The perinuclear theca 32 (PT32) protein is disclosed and shown to interact with tyrosine kinase c-Yes. PT32, c-Yes, fragments thereof, and molecules that bind thereto can be used in methods of...
|
|
|
7384767 |
Nucleic acid encoding an interleukin-9 receptor variant
This invention relates to the diagnosis, treatment and methods for discovery of new therapeutics for atopic asthma and related disorders based on variants of Asthma Associated Factor 2. One...
|
|
|
7384750 |
Nucleic acid sequences having characteristics of enhanced expression in human neuroblastoma with favorable prognosis based on comparison between human neuroblastoma with favorable prognosis and human neuroblastoma with unfavorable prognosis
There are disclosed a nucleic acid which is derived from the gene expressed in human neuroblastoma, and which comprises any sequence selected from the group consisting of the nucleic acid sequences...
|
|
|
7384745 |
Nucleic acid sequences found in Drosophila melanogaster that encode proteins essential for viability and method of use
Within the unique Triplo-lethal region (Tpl) of the Drosophila melanogaster genome we have found a cluster of 20 genes encoding a novel family of proteins. This family is also present in the ...
|
|
|
7384740 |
Polynucleotide and protein involved in synaptogenesis variants thereof and their therapeutic and diagnostic uses
The present invention provides a method of diagnosing autism linked to a mutation in the polynucleotide of SEQ ID NO: 12 or the polypeptide of SEQ ID NO: 14, or a propensity therefor, in a human,...
|
|
|
RE40374 |
Canine IL-13 immunoregulatory proteins and uses thereof
The present invention relates to canine interleukin-4, canine or feline Flt-3 ligand, canine or feline CD40, canine or feline CD154, canine interleukin-5, canine interleukin-13, feline interferon...
|
|
|
7381813 |
Nucleic acids encoding estrogen receptor ligand binding domain variants
Mutants of steroid receptor ligand binding domains and synthetic ligands which have specific binding affinities for these receptors are provided. The use of these LBD-ligand combinations for...
|
|
|
7381542 |
Nucleic acids encoding a biogenic amine receptor
The present invention relates to novel mammalian biogenic amine receptor proteins and genes that encode such proteins. The invention is directed toward the isolation and characterization of...
|
|
|
7381411 |
Aglyco products and methods of use
Glycoconjugates, therapeutic compositions containing the glycoconjugates and therapeutic methods of using the glycoconjugates are disclosed. In particular, peptide constituents of aglyco 10B, which...
|
|
|
7381405 |
Methods of preparing lymphocytes that express interleukin-2 and their use in the treatment of cancer
The invention provides methods of preparing autologous T-lymphocytes for re-introduction into a patient having cancer, which method comprises obtaining peripheral blood mononuclear cells (PBMCs)...
|
|
|
7378498 |
Protein encoded by a nucleic acid
A method is provided for identifying a compound that modulates a cellualr response associated with Homer and mediated by a cell-surface or an intracellular receptor. A method is further provided...
|
|
|
7378492 |
CD40-related receptor that binds CD40L
Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and Q polynucleotides which identify and encode REMAP. Embodiments of the invention also...
|
|
|
7378275 |
Canine IL-13 receptor alpha-1 subunit nucleic acid molecules
The invention relates to canine immunoglobulin G (IgG) and canine interleukin-13 receptors (IL-13R) as well as fusion proteins containing canine IgG and/or canine IL-13R. In particular, the present...
|
|
|
7378239 |
Method of differentiating between ulcerative colitis and Crohn's disease
The differentiation between ulcerative colitis and Crohn's disease is made possible by a multi-gene approach where gene expression profiles in biopsy samples obtained from inflamed, and optionally...
|
|
|
7375207 |
Galanin receptor 2 proteins and nucleic acids
The present invention is directed to galanin receptor 2 (GAL-R2) proteins and nucleic acids.
|
|
|
7375206 |
Brother of the regulator of imprinted sites (BORIS)
An isolated or purified nucleic acid molecule consisting essentially of a nucleotide sequence encoding a human or a non-human BORIS, or a fragment of either of the foregoing; an isolated or...
|
|
|
7375203 |
Canine cold- and menthol-sensitive receptor 1
The present invention provides nucleic acid and polypeptide sequences describing a novel canine cold- and menthol-sensitive receptor, herein named as canine CMR1 (cCMR1). The isolated nucleic acid...
|
|
|
7375201 |
Fluorescent protein
An object of the present invention is to provide a fluorescent protein derived from organisms other than Aequorea victoria and having a novel primary structure. According to the present...
|
|
|
7375079 |
Previns as specific inhibitors and therapeutic agents for botulinum toxin B and tetanus neurotoxins
The compounds of the invention are generally described by the formula:
B 1 Z* 2 B 3 Z* 4 X* 5 Q 6 F 7 X 8 X 9 X 10 X 11 , ...
|
|
|
7374935 |
Human Rgr oncogene and truncated transcripts thereof detected in T cell malignancies, antibodies to the encoded polypeptides and methods of use
Naturally-occurring variants of human Rgr oncogene protein, in particular, abnormally truncated variants found in T cell malignancies, as well as the human Rgr protein are encompassed by the...
|
|
|
7374911 |
Interleukin-1 related gene and protein
Disclosed in an interleukin-1 related gene and gene product. In particular, the invention relates to a protein that is highly homologous to known interleukin-1 cytokines, nucleic acid molecules...
|
|
|
7374910 |
DNA encoding galanin receptor activating peptide
The present invention relates to a peptide comprising an amino acid sequence identical to or substantially identical to an amino acid sequence represented by SEQ ID NO: 35 and having an ability of...
|
|
|
7374909 |
Modulators of intracellular inflammation, cell death and cell survival pathways
A B1 protein, its isoforms, analogs, fragments and derivatives, DNA encoding it and recombinant production are provided. The protein is useful in the modulation of intracellular inflammation, cell...
|
|
|
7374884 |
Diabetes gene
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect human diabetes mellitus...
|
|
|
7371845 |
MAGE-A3 peptides presented by HLA class II molecules
The invention describes HLA class II binding peptides encoded by the MAGE-A3 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides...
|
|
|
7371844 |
Nucleic acids encoding parathyroid hormone (PTH) derivatives
Parathyroid hormone(PTH) polypeptide derivatives are disclosed, as are pharmaceutical compositions containing said polypeptides, and synthetic and recombinant methods for producing said...
|
|
|
7371843 |
Cultured Xenopus laevis cell lines expressing mutant Adenomatous polyposis coli gene
Using protein visualization techniques, cell lines stably expressing GFP-fused full-length and mutant APCs were obtained from cultured Xenopus laevis renal epithelial A6 cells. The use of these...
|
|
|
7371842 |
Polynucleotide encoding a 35 KDA protein thats binds to WF00144
It is intended to provide a protein participating in the regulation of sugar production, a polynucleotide encoding the same, a method of screening a compound participating in the regulation of...
|
|
|
7371841 |
Methods of modulating cold sensory perception
The present invention relates to regulation of cold sensation and pain. More particularly, the present invention is directed to nucleic acids encoding a member of the transient regulatory protein...
|
|
|
7371840 |
Isolation and characterization of ECA1, a gene overexpressed in endometrioid carcinomas of ovary and endometrium
This invention provides an isolated polynucleotide encoding an ECA1 polypeptide. Also provided is the isolated ECA1 polypeptide Further provided is an antibody that specifically recognizes and...
|
|
|
7371836 |
PRO526 nucleic acids
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host ceolls comprising those nucleic acid...
|
|
|
7371824 |
PRO6093 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
|
|
|
7371823 |
Cyclic nucleotide-gated cation channel subunit 3B (CNG3B) polypeptides
The invention provides isolated nucleic acid and amino acid sequences of CNG3B, antibodies to CNG3B, methods of detecting CNG3B, and methods of screening for modulators of cyclic nucleotide-gated...
|
|
|
7371559 |
Peptides and related molecules that modulate nerve growth factor activity
The present invention relates to certain biologically active peptides and polypeptides which can be used as therapeutics or prophylactics against diseases or disorders linked to NGF as the...
|
|
|
7371541 |
G proteins, polynucleotide encoding the same and utilization thereof
We identified a novel protein (Gm1) comprising an amino acid sequence part having a high homology with a domain having a high homology with a GTP binding site and a GTPase site conserved among G...
|
|
|
7371540 |
Gene expression control DNA element and associated protein
Through screening of an expression library, a cDNA sequence has been identified that encodes a protein that interacts with human CD33, the DNA being highly homologous to a portion of the human...
|
|
|
7371535 |
Processes for determining compounds that interact with snorf33 receptor
This invention provides isolated nucleic acids encoding mammalian SNORF33 receptors, purified mammalian SNORF33 receptors, vectors comprising nucleic acid encoding mammalian SNORF33 receptors,...
|
|
|
7371382 |
Methods of inhibiting αvβ3-mediated binding with αvβ3-specific antibodies
The invention provides enhanced LM609 grafted antibodies exhibiting selective binding affinity to α V β 3 , or a functional fragment thereof. The invention also provides nucleic acid molecules...
|
|
|
7371207 |
Estrogen receptor α regulated gene expression, related assays and therapeutics
A plurality of genes modulated by estrogen or other agents, such as hormones or combinations of hormones, in various types of tissue is described. One embodiment of the disclosure relates to a...
|
|
|
7368554 |
Polynucleotides encoding BSL2v1c2-Ig
The present invention provides nucleic acids encoding B7-related factors that modulate the activation of immune or inflammatory response cells, such as T-cells. Also provided are expression vectors...
|
|
|
7368553 |
Alternatively spliced nucleic acid molecules
The invention provides an isolated or purified nucleic acid molecule comprising SEQ ID NO:1, which contains cDNA comprising exons 1-5 of a vascular endothelial growth factor (VEGF) joined to...
|