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7238479 |
Single nucleotide polymorphism markers in the bovine CAPN1 gene to identify meat tenderness
Single nucleotide polymorphisms (SNPs) in the gene encoding micromolar calcium activated neutral protease (mu-calpain) effect meat tenderness in bovine. These SNPs correspond to position 18 of exon...
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7235241 |
Monomer protein with bone morphogenetic activity and medicinal agent containing the same for preventing and treating diseases of cartilage and bone
This invention provides for a protein of the TGF-β superfamily in which the cysteine involved in the normal formation of homodimers is changed to another amino acid. These mutant proteins, as...
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7235634 |
2786, a novel human aminopeptidase
The present invention relates to a newly identified human aminopeptidase. The invention also relates to polynucleotides encoding the aminopeptidase. The invention further relates to methods using...
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7235637 |
IL-1 eta DNA and polypeptides
The invention is directed to novel, purified and isolated IL-1 eta polypeptides and fragments thereof, the polynucleotides encoding such polypeptides, processes for production of recombinant forms...
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7235381 |
Expressed sequence tags and encoded human proteins
The sequences of 5′ ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5′ ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5′ ESTs. The 5′ ESTs may also...
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7232682 |
Expression vectors encoding epitopes of target-associated antigens and methods for their design
The invention disclosed herein is directed to methods of identifying a polypeptide suitable for epitope liberation including, for example, the steps of identifying an epitope of interest; providing...
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7232659 |
Multiplex analysis for high throughput discrimination of GPCR agonists and antagonists
The present invention relates generally to molecular assemblies, more particularly to an assay for the detection of G-protein coupled receptor (GPCR) molecular assemblies and bead-based detection...
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7232674 |
Process for producing α1,4-galactosyltransferase and galactose-containing complex sugar
The present invention can provide a process for producing a protein having α1.4-galactosyltransferase activity using a transformant comprising a DNA encoding a protein having...
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RE39696 |
Human cyclooxygenase-2 cDNA and assays for evaluating cyclooxygenase-2 activity
The invention discloses a human cyclooxygenase-2 cDNA, a human cyclooxygenase-2 and assays for preferentially and independently measuring cyclogenase-2 or cyclooxygenase-1 activity present in a...
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7229790 |
Human GABA transporter protein and polynucleotides encoding the same
Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
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7230078 |
Soluble toll-like receptor
A novel, soluble protein similar to the known Toll-like receptor (TLR) family is disclosed. The present invention relates to these new soluble polypeptides, to nucleotide sequences encoding the...
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7226756 |
Purified plant expansin proteins and DNA encoding same
This invention relates to a new class of proteins called expansins, and methods related thereto are presented. This class of proteins can be characterized as catalysts of the extension of plant...
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7226772 |
Recombinant xylanases derived from anaerobic fungi, and the relevant sequences, expression vectors and hosts
The present invention provides recombinant xylanases which are derived from anaerobic fungi, particularly Neocallimastix frontalis and N. patriciarum . The enzymes are thermo- and alkaline...
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7226731 |
PB 39, a gene dysregulated in prostate cancer, and uses thereof
A novel gene, PB39, that is up-regulated, or over-expressed, in prostate cancer has been identified. The gene has been identified by means of its cDNA obtained by reverse transcription of the...
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7226999 |
Protein C or activated protein C-like molecules
The present invention relates to novel conjugates between polypeptide variants of protein C and a non-polypeptide moiety, such as PEG or sugar moieties. In particular, the present invention...
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7226776 |
Recombinant hosts suitable for simultaneous saccharification and fermentation
The invention provides recombinant host cells containing at least one heterologous polynucleotide encoding a polysaccharase under the transcriptional control of a surrogate promoter capable of...
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7223578 |
Canine COX-1 nucleic acid molecules and fragments thereof
The present invention relates to canine COX-1 and COX-2 proteins; to canine COX-1 and COX-2 nucleic acid molecules, including those that encode such COX-1 and COX-2 proteins, respectively; to...
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7223564 |
Four-helical bundle protein zsig81
This present invention is directed to polypeptide and polynucleotide molecules that encode a four-helical bundle cytokine. The cytokine has been designated zsig81, and has restricted expression in...
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7223853 |
Secreted frizzled related protein fragments
The invention stems from the discovery that sFRP and fragments thereof can bind to members of the Wnt family of proteins and cause an increase in Wnt biological activity. Furthermore, fragments of...
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7223852 |
Nucleic acids encoding TRAIN-R: a cysteine rich member of the TNF-receptor family
The present invention relates to novel receptors in the TNF family. A novel receptor has been identified, referred to herein as TRAIN. The invention relates to DNA sequences encoding TRAIN...
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7223839 |
Histamine receptor H3 polynucleotides
Novel splice variants of the human H3 histamine receptor are described. The splice variants have deletions of portions of the N-terminal of the wild type H3 receptor. The splice variants are useful...
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7220851 |
Nucleic acid encoding calcyon, a D-1 like dopamine receptor activity modifying protein
A number of cDNA clones whose products may interact with D1 receptors in vivo were identified. One of the clones, P24, was characterized further. P24 is localized in dendrites and spines of...
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7220568 |
Nucleic acids encoding the PRO1561 polypeptide
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7220579 |
Identification of the gene causing the mouse scurfy phenotype and its human ortholog
Isolated nucleic acid molecules are provided which encode Fkh sf , as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and...
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7220556 |
Preparation of factor XIIIa by gene manipulation
The cDNA which codes for factor XIIIa has been isolated using a cDNA bank from human placenta and probes constructed on the basis of the amino acid sequence of factor XIIIa peptide fragments. It is...
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7220581 |
Schizophrenia related gene
The invention relates to polynucleotides of the PAPAP gene, polypeptides encoded by the PAPAP gene, and antibodies directed specifically against such polypeptides. The invention also concerns...
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7220841 |
Antibody to PRO1557 polypeptide encoded by a nucleic acid highly expressed in esophageal and kidney tumors
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7220580 |
Sphingosine 1-phosphate receptor gene, sppr
A novel sphingosine 1-phosphate receptor gene, herein termed sppr, and its splice variants. Sppr is up-regulated in LGL and is useful, for example, in the diagnosis and treatment of certain...
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7220558 |
Cartilage-derived morphogenetic proteins
Nucleotide and amino acid sequences of cartilage-derived morphogenetic proteins (CDMP-1 and CDMP-2) from human and bovine cartilage extracts. These proteins exhibit chondrogenic activity and can be...
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7220555 |
Practical in vitro sialylation of recombinant glycoproteins
This invention provides methods for practical in vitro sialylation of glycoproteins, including recombinantly produced glycoproteins. The methods are useful for large-scale modification of...
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7220828 |
Haemopoietin receptor and genetic sequence encoding same
The present invention relates generally to a novel haemopoietin receptor or derivatives thereof and to genetic sequences encoding same. Interaction between the novel receptor of the present...
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7220849 |
Enhanced gamma-carboxylation of recombinant vitamin K-dependent clotting factor
The invention relates to methods of optimizing gamma carboxylation of a vitamin K-dependent protein, methods of generating fully gamma carboxylated vitamin K-dependent protein, and compositions...
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7220557 |
METH1 polynucleotides
The present invention relates to novel anti-angiogenic proteins, related to thrombospondin. More specifically, isolated nucleic acid molecules are provided encoding human METH1 and METH2. METH1 and...
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7217789 |
Fluorescent timer proteins and methods for their use
Fluorescent timer proteins, which undergo a spectral shift over time after synthesis, as well as nucleic acid compositions encoding the same, are provided. Also provided are fragments of the...
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7217548 |
N-acetylglucosaminlytransferase and polynucleotide encoding the same
The present invention relates to an enzyme having novel N-acetylglucosaminyltransferase (OMGnT) activity, a polynucleotide encoding the enzyme, a recombinant polynucleotide comprising the...
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7217433 |
Animal feed additives
The present invention relates to animal feed additives, which additives comprise a monocomponent xylanase derived from a strain of Byssochlamus, Chaetomium, Humicola, Malbranchea, Mucor,...
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7217811 |
Human gene critical to fertility
Disclosed herein are novel nucleic acid and protein sequences that are essential to fertility. In particular, human Mater cDNA and protein sequences are provided. Functional MATER is required for...
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7217553 |
Nucleic acids encoding human adamalysin SVPH1-8
The disclosure provides purified and isolated SVPH1–8 polypeptides, nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies...
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7217790 |
UMLR polypeptides
Novel secreted and membrane bound tumor necrosis factor receptor (TNFR) polypeptides, polynucleotides encoding the polypeptides, antibodies and related compositions and methods are disclosed. The...
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7217806 |
Gene defective in APECED and its use
The present invention relates to a novel gene, a novel protein encoded by said gene, a mutated form of the gene and to diagnostic and therapeutic uses of the gene or a mutated form thereof. More...
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7217540 |
Polynucleotide encoding IL-1 zeta, TDZ.1 isoform polypeptide
The invention is directed to novel, purified and isolated IL-1 zeta and Xrec2 polypeptides and fragments thereof, the nucleic acids encoding such polypeptides, processes for production of...
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RE39614 |
Canine IL-4 immunoregulatory proteins and uses thereof
The present invention relates to canine interleukin-4, canine or feline Flt-3 ligand, canine or feline CD40, canine or feline CD154, canine interleukin-5, canine interleukin-13, feline interferon...
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7214533 |
Polynucleotide useful for modulating cancer cell proliferation
The invention concerns a novel protein modulating cancer cell proliferation. The proteins encoded by the polynucleotides of the invention enable to determine the degree of malignity of abnormal...
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7214784 |
Protective antigens for the control of Ixodes species infestations
Protective antigens against infestations with Ixodes spp. ticks, gene sequences and encoded proteins for such antigens, related vaccines and methods useful to induce an immune response, which are...
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7214534 |
Isolated nucleic acid molecules encoding mutant μ opioid receptors
The invention provides genetic approaches to inhibit or treat pain which employ mutant μ opioid receptors.
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7214511 |
Hormone receptor compositions and methods
In accordance with the present invention, there are provided expression systems for the production of function glucocorticoid receptor proteins, methods for the recombinant production of...
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7214521 |
Inulin synthase and process for producing inulin by using the same
The present invention relates to a novel inulin synthase having a function and a substrate specificity of acting on sucrose to produce inulin, but not acting on kestose, maltose, lactose, trehalose...
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7214483 |
KCNQ2 and KCNQ3—potassium channel genes which are mutated in benign familial neonatal convulsions (BFNC) and other epilepsies
Generalized idiopathic epilepsies (IGE) cause 40% of all seizures and commonly have a genetic basis. One type of IGE is Benign Familial Neonatal Convulsions (BFNC), a dominantly inherited disorder...
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7214513 |
Transcriptional regulatory factor
BLAST search was done on the EST database by using various nucleotide sequences encoding known bromodomain motifs to discover several ESTs likely encoding bromodomain genes. Next, testicular cDNAs...
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7214782 |
Nucleic acid of novel human kinesin-related gene protein encoded by the nucleic acid peptide fragment thereof and anticancer agents comprising the nucleic acid and the like
There are provided base sequence data for human kinesin-related genes with a motor domain, as well as information relating to the functions of the proteins encoded by the human kinesin-related gene...
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