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7390894 Glutathione S-transferase sequence variants  
Isolated GSTO2 nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as GSTO2 allozymes. Methods for determining if...
7390892 Nucleic acids encoding novel cyclic GMP dependent protein kinases from Elmeria maxima  
The present invention relates to novel protozoal cyclic GMP dependent protein kinases and genes encoding same that have been isolated from Eimeria maxima and Plasmodium falciparum . Nucleic acid...
7390891 Polynucleotides encoding a telomerase component TP2  
Disclosed are nucleic acid molecules encoding polypeptides of the telomerase complex. Also disclosed are methods of preparing the nucleic acid molecules and polypeptides, and methods of using these...
7390643 Geranyl diphosphate synthase molecules, and nucleic acid molecules encoding same  
In one aspect, the present invention provides isolated nucleic acid molecules that each encode a geranyl diphosphate synthase protein, wherein each isolated nucleic acid molecule hybridizes to a...
7390642 Salutaridinol 7-O-acetyltransferase and derivatives thereof  
This invention provides: (A) a protein the sequence of which is in FIG. 8 (SEQ. ID n° 14), or a fragment thereof having at least 15 amino acids, or a variant thereof, having at least 70%...
7390485 Design and therapeutic use of adpase enhanced apyrases  
The present invention provides for design and therapeutic use of ADPase enhanced polypeptides, pharmaceutical compositions, and methods useful for preventing and reversing platelet aggregation and...
7388084 Promoter motifs in Candida tropicalis  
The present invention provides modified promoters from Candida troplicalis CYP and POX4 genes. The modified promoters have various sequence motifs added, deleted, or altered in order to modulate...
7387893 Vectors, cells and processes for pyrimidine deoxyribonucleosides production  
Novel DNA constructs and host cells comprising the same are disclosed. DNA constructs comprise a transcription unit (e.g. operon) comprising DNA sequences encoding for ribonucleotide reductase and...
7385104 Plants synthesizing a modified starch, a process for the generation of the plants, their use, and the modified starch  
The present invention relates to recombinant nucleic acid molecules which contain two or more nucleotide sequences which encode enzymes which participate in the starch metabolism, methods for...
7384787 Increasing perhydrolase activity in esterases and/or lipases  
The invention provides for methods of modifying n esterase or a lipase enzyme to introduce perhydrolase activity or to increase the already-existing perhydrolase activity. The invention also...
7381555 Lactobacillus N-deoxyribosyl transferases, corresponding nucleotide sequences and their uses  
The invention concerns novel polypeptides and their fragments, isolated from Lactobacillus , having at least a N-deoxyribosyl transferase activity, the polynucleotides encoding said polypeptides,...
7381554 UDP-N-acetylglucosamine: galactose-β1,3-N-acetylgalactosamine-α-R/N-acetylglucosamine-β1,3-N-acetylgalactosamine-α-R (GlcNAc to GalNAc) β1,6-N-acetylglucosaminyltransferase, C2/4GnT  
A novel gene defining a novel human UDP-GlcNAc: Gal/Gl cNAcβ 1-3GalNAc αβ1, 6GlcNAc-transferase, termed C2/4GnT, with unique enzymatic properties is disclosed. The enzymatic activity of C2/4GnT...
7381553 Highly active xylose reductase from Neurospora crassa  
A new xylose reductase encoding gene from Neurspora crassa was heterologously expressed in E. coli as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was...
7381544 Nucleic acid that encodes a fusion protein  
This invention provides fusion polypeptides that include a glycosyltransferase catalytic domain and a catalytic domain from an accessory enzyme that is involved in making a substrate for a...
7378512 Production of proteins by autoproteolytic cleavage  
The present invention relates to a process for the production of a heterologous polypeptide with homogeneous N-terminus in a bacterial host cell, wherein the heterologous polypeptide is...
7378264 α-amylase mutants  
The present invention relates to a method of constructing a variant of a parent Termamyl-like α-amylase, which variant has α-amylase activity and at least one altered property as compared to the...
7378263 In vivo site-specific incorporation of N-acetyl-galactosamine amino acids in eubacteria  
Methods and compositions for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid having a N-acetylgalactosamine moiety into a...
7375205 Elongase genes and uses thereof  
The subject invention relates to the identification of several genes involved in the elongation of polyunsaturated fatty acids (i.e., “elongases”) and to uses thereof. At least two of these...
7375203 Canine cold- and menthol-sensitive receptor 1  
The present invention provides nucleic acid and polypeptide sequences describing a novel canine cold- and menthol-sensitive receptor, herein named as canine CMR1 (cCMR1). The isolated nucleic acid...
7375091 HER-2/neu fusion proteins  
The present invention is generally directed to HER-2/neu fusion proteins, nucleic acid molecules encoding HER-2/neu fusion proteins, viral vectors expressing HER-2/neu fusion proteins, and...
7374933 Human metalloprotease and polynucleotides encoding the same  
Novel human polynucleotide and polypeptide sequences are disclosed that can be used in thereapeutic, diagnostic, and pharmacogenomic applications.
7374932 Human kinases and polynucleotides encoding the same, and uses thereof  
Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
7374923 Polypeptide  
A screening tool and a screening method for a therapeutic agent for type II diabetes, particularly an agent for alleviating insulin resistance are disclosed. A novel polypeptide, a polynucleotide,...
7374922 Starch debranching enzymes  
The invention relates to a genetically engineered variant of a parent starch debranching enzyme, i.e. a pullulanase or an isamylase, the enzyme variant having an improved thermostability at a pH in...
7374921 Cellulase tolerant to surfactants  
Disclosed is a novel cellulase having an amino acid sequence in which the 162nd and/or 166th amino acid residues in the amino acid sequence of cellulase NCE5 are substituted. Further, a...
7374920 Ginkgo biloba levopimaradiene synthase  
The present invention is directed to nucleic acid sequences of Ginkgo biloba diterpene synthases, particularly of a levopimaradiene synthase. More specifically, the invention is directed to a...
7374918 Modified sarcosine oxidases, genes and recombinant DNAs thereof, and methods for preparing the same  
An isolated DNA molecule encoding modified sarcosine oxidases having optimal pH, high activity in the slightly acidic range and improved stability and a method for preparing the modified sarcosine...
7374917 Mutant 2.5-diketo-L-gluconic acid reductases  
Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated...
7374899 Sucrose-6-phosphate phosphatase as target for herbicides  
The present invention relates to the use of a polypeptide with the biological activity of a sucrose-6-phosphate phosphatase which, if not present, brings about growth retardation symptoms and...
7371839 Alkaline proteases  
The present invention relates to alkaline proteases having high specific activity and strong oxidant resistance. The present invention also relates to alkaline proteases having excellent detergency...
7371838 Nucleic acids encoding β 1,4-N-acetylgalactosaminyltransferases from C. jejuni  
This invention provides prokaryotic β1,4-N-acetylglucosaminyl (GalNAc) traosferases involved in synthesis of lipooligosaccharide (LOS). The β1,4-GalNAc transferases can be obtained from, for...
7371571 Recombinant mycobacteria overexpressing D-alanine ligase gene and uses therefore  
Recombinant mycobacterial strains which overproduce essential biosynthetic enzymes of pathogenic mycobateria are provided. These strains overproduce enzymes involved in the synthesis and...
7371560 Photosynthetic hydrogen production  
A process for the production of hydrogen, comprising the steps of: (i) providing a photosynthetic microorganism having electron transfer capability through a photosynthetic light reaction pathway...
7371558 Process for the biological production of 1,3-propanediol with high yield  
The present invention provides a microorganism useful for biologically producing 1,3-propanediol from a fermentable carbon source at higher yield than was previously known. The complexity of the...
7371555 Polypeptides having α-H-α-amino acid amide racemase activity and nucleic acids encoding the same  
The invention relates to isolated polypeptides having α-H-α-amino acid amide racemase activity and nucleic acids encoding the same. The invention also relates to vectors and host cells comprising...
7371554 Isozymes of lacrimator component synthase and gene encoding the same  
It is an object of the present invention to provide isozymes of the lachrymatory factor producing enzyme, the amino acid sequences of these isozymes and a gene that codes for these amino acid...
7371553 Chemically modified enzymes with multiple charged variants  
This invention provides modified enzymes comprising one or more amino acid residues replaced by cysteine residues, where the cysteine residues are modified by replacing the thiol hydrogen in the...
7371552 Polypeptide  
We disclose a food additive comprising a PS4 variant polypeptide, in which the PS4 variant polypeptide is derivable from a parent polypeptide having non-maltogenic exoamylase activity, in which the...
7371551 Feedback-resistant homoserine transsuccinylases  
The invention concerns a homoserine transsuccinylase having at least one mutation compared to a wild-type homoserine transsuccinylase and reduced sensitivity towards a L-methionine or SAM, compared...
7371550 Cholesterol oxidase stable in the presence of surfactant  
A novel cholesterol oxidase having stability in the presence of surfactant and a gene encoding the novel cholesterol oxidase.
7371549 Aldolase, and method for producing optically active IHOG and monatin  
The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for...
7371548 Avermectin aglycon synthase genes  
The present invention relates to an isolated DNA which comprises a DNA sequence encoding avermectin aglycon synthase domains that corresponds to multifunctional enzyme proteins involved in the...
7371547 Process for producing vitamin B6  
Disclosed is a mutant of a recombinant microorganism of the genus Sinorhizobium capable of producing vitamin B 6 having a recombinant plasmid with pdxJ gene that acquired histidine requirement...
7371546 Glucoamylase variants  
The invention relates to a variant of a parental fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
7368293 Liver enriched transcription factor  
HNF-4 (hepatocyte nuclear factor 4) is a protein enriched in liver extracts that binds to sites required for the transcription of the transthyretin (TTR) and apolipoprotein CIII (apoCIII) genes...
7368284 Porcine CMP-N-Acetylneuraminic acid hydroxylase gene  
The present invention provides porcine CMP-N-Acetylneuraminic-Acid Hydroxylase (CMP-Neu5Ac hydroxylase) protein, cDNA, and genomic DNA regulatory sequences. Furthermore, the present invention...
7368276 Polynucleotide constructs encoding aspartate kinase, aspartate-semialdehyde dehydrogenase, and dihydrodipicolinate reductase and related constructs, products, and methods  
The invention relates to production of lysine, and provides several isolated polynucleotide molecules useful for the production of L-lysine. One such polynucleotide encodes an aspartate kinase...
7368274 Expression of recombinant proteinase K from Tritirachium album in yeast  
The invention concerns a method for the expression of a gene coding for a soluble proteinase K in yeast e.g. in Pichia pastoris with subsequent secretion into the culture medium. In addition a...
7368271 Polypeptides having alpha-glucosidase activity and polynucleotides encoding same  
The present invention relates to isolated polypeptides having alpha-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid...
7368270 Human phospholipases  
The invention provides human lipid metabolism enzymes (LME) and polynucleotides which identify and encode LME. The invention also provides expression vectors, host cells, antibodies, agonists, and...