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7445922 |
Zygomycetes-derived endoglucanase enzyme lacking cellulose-binding domain
This invention relates to a protein that is a Zygomycetes -derived endoglucanase lacking the cellulose-binding domain and exhibits endoglucanase activity, and a method for using the same. This...
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7446187 |
Plasmids and utilization thereof
A shuttle vector is constructed by preparing a DNA region replicable in bacteria belonging to the genus Rhodococcus from a Rhodococcus -derived plasmid having the nucleotide sequence set forth...
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7446188 |
Plant cyclopropane fatty acid synthase genes, proteins, and uses thereof
The present invention provides cyclopropane fatty acid synthase genes and proteins, and methods of their use. The present invention encompasses both native and recombinant wild-type forms of the...
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7446192 |
Gene participating in acetic acid tolerance, acetic acid bacteria bred using the gene, and process for producing vinegar with the use of the acetic acid bacteria
The present invention is intended to provide novel genes participating in acetic acid tolerance of acetic acid bacteria, and a method of improving acetic acid tolerance of microorganisms,...
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7445915 |
Mutant isopropylmalate isomerase
The present invention provides a polypeptide comprising an amino acid sequence in which at least one amino acid is deleted, substituted or added in an amino acid sequence of isopropylmalate...
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7445919 |
Zsig33-like peptides and polynucleotides
The present invention relates to polynucleotide related to the zsig33 peptide, including agonists, antagonists, and antibodies. Methods of modulating gastric contractility, nutrient uptake, growth...
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7445920 |
Member of the lysyl oxidase gene family
The present invention relates to a novel lysyl oxidase genes, termed EER-7. The invention relates to the protein and nucleic acids encoding the protein. The invention further relates to an assay...
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7445917 |
Process for producing glycolic acid from formaldehyde and hydrogen cyanide
A process is provided for producing glycolic acid from formaldehyde and hydrogen cyanide. More specifically, heat-treated formaldehyde and hydrogen cyanide are reacted to produce glycolonitrile...
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7442535 |
Fusion protein incorporating a cysteinized ribonuclease
A fusion protein contains a cysteinized variant of an RNase disclosed in U.S. Pat. No. 6,239,257 B1.
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7442500 |
Methods of diagnosing susceptibility to obesity
A gene expression pattern analysis has identified genes the expression patterns of which are different in adipose cells of individuals who have Type 2 Diabetes Mellitus from the cells of...
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7442398 |
Phytase produced from Citrobacter braakii
The present invention relates to phytase enzyme, a gene encoding the enzyme, and a Citrobacter sp. producing the enzyme. Particularly, the present invention relates to the phytase enzyme produced...
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7442532 |
Essential fungal CaYLR100w polypeptides, and methods of use
The present invention provides essential fungal polynucleotides and their encoded polypeptides, homologues thereof and their uses. Additionally, the invention provides methods for the...
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7442851 |
Plant isoflavonoid hydroxylases and methods of use thereof
The invention provides plant isoflavonoid hydroxylase coding sequences. Also provided are constructs comprising these sequences, plants transformed therewith and methods of use thereof. In certain...
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7439061 |
DNA encoding the novel mammalian protein, Ire1p
A novel polynucleotide encoding a mammalian bifunctional protein kinase\endoribonuclease referred to herein as hIre1p, is provided. hIre1p is expressed in the endoplasmic reticulum (ER) and...
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7439034 |
Alginases, systems containing alginases and methods of cloning, purifying and/or utilizing alginases
The present invention relates to cell wall degradative systems, in particular to systems containing enzymes that bind to and/or depolymerize cellulose. These systems have a number of applications.
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7439050 |
Corynebacterium glutamicum genes encoding diaminopimelate epimerase
Isolated nucleic acid molecules, designated MP nucleic acid molecules, which encode novel MP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic...
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7439419 |
Solanum tuberosum β-solanine/β-chaconine rhamnosyl transferase sequences and uses thereof
Nucleic acid sequences from potato that encode the enzyme β-solanine/β-chaconine rhamnosyltransferase (SGT3) are disclosed. Recombinant DNA molecules containing the sequences, and use thereof, in...
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7439049 |
Nucleic acid molecules coding for a dextran-saccharase catalysing the synthesis of dextran with α 1,2 osidic sidechains
The invention relates to an isolated polypeptide with an glycosyl transferase enzymatic activity for producing dextrans with α(1→2) sidechains, comprising at least one region for bonding to...
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7435583 |
Membrane fractions of 1,2-sn-diacylglycerol-enriched cells
The invention concerns membrane fractions of cells containing a recombinant MGDG synthase and enriched with 1,2-sn-diacylglycerol, their preparation method, their use for screening molecules...
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7435571 |
Microbial production of COQ10
The present Invention relates to enzymes involved in the Synthesis of Coenzyme Q-10, i.e., decaprenyl diphosphate (DPP) synthase and 4-hydroxybenzoate polyprenyltransferase, to isolated DNA...
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7435570 |
Thermostable peroxide-driven cytochrome P450 oxygenase variants and methods of use
The invention relates to novel variants of cytochrome P450 oxygenases. These variants have at least one mutation improving their ability to use peroxide as an oxygen donor as compared to the...
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7435556 |
Method for increasing the ratio of p-hydroxybenzoic acid ester glucoside to total p-hydroxybenzoic acid glucose conjugates in p-hydroxybenzoic acid-producing microorganisms and green plant cells
This invention pertains to a method for increasing the ratio of the pHBA ester glucoside to total pHBA glucose conjugates in pHBA-producing microorganisms and green plant cells using nucleic acid...
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7435574 |
NADH oxidase from Lactobacillus
The present invention is directed to a new NADH oxidase from Lactobacillus , nucleic acids encoding the NADH oxidase, methods of producing the NADH oxidase, as well as there use in producing...
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7435584 |
L-lysine-producing corynebacteria and process for the preparation of L-lysine
The invention relates to L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the...
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7432089 |
DNA encoding favin-adenine-dinucleotide-dependent-D-erythronate-4-phosphate-de-hydrogenase, pdxR, and microbial production of vitamin B6
The present invention relates to a DNA encoding a novel flavin adenine dinucleotide (FAD)-dependent D-erythronate 4-phosphate (EN4P) dehydrogenase originated from Sinorhizobium meliloti , which is...
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7432100 |
Variant aldolase and processes for producing an optically active IHOG and an optically active monatin using the same
The present invention relates to variant aldolase enzymes that are modified so as to produce IHOG (4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid: IHOG), a process for producing an optically...
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7432095 |
Formate dehydrogenase tolerant to halogen compounds and process for producing the same
The invention provides a formate dehydrogenase having high specific activity, small Km values for formate and NAD, broad temperature and pH ranges of stability, broad temperature and pH ranges for...
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7432096 |
Glucose dehydrogenase and production thereof
The invention relates to novel PQQ-dependent soluble glucose dehydrogenases (sPQQGDH) from Acinetobacter and to a process for their preparation by overexpression in suitable microbial expression...
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7432099 |
Amylase variants
The present invention relates to variants (mutants) of polypeptides, in particular Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits an alteration in at least one...
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7432246 |
Sir2 products and activities
A novel compound, 2′/3′-O-acetyl-ADP-ribose, is provided. The compound is a mixture of the 2′ and 3′ regioisomers of O-acetyl-ADP ribose, and is formed nonenzymatically from...
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7432098 |
Phytases and methods for making and using them
The invention provides isolated and recombinant phytase enzymes. In one aspect, the phytases are produced by modification of the wild type appA of E. coli. The enzyme can be produced from...
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7432085 |
Method for producing L-amino acid
In a method for producing an L-amino acid by culturing a microorganism having an ability to produce an L-amino acid in a medium to produce and accumulate the L-amino acid in the medium and...
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7432097 |
Phytases, nucleic acids encoding them and methods of making and using them
In one aspect, the invention provides a purified and modified phytase enzyme from Escherichia coli K12 appA phytase. The enzyme has phytase activity and improved thermal tolerance as compared...
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7429474 |
2-O sulfatase compositions and methods of analyzing therewith
The invention relates to 2-O sulfatase and uses thereof. In particular, the invention relates to recombinantly produced 2-O sulfatase, functional variants and nucleic acid molecules that encode...
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7429476 |
Acid fungal proteases
The present invention is directed to novel acid proteases and more specifically to NSP24 family proteases and NSP25 family proteases including biologically active fragments thereof and to nucleic...
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7429469 |
Enzyme gene participating in the synthesis of polyester and process for producing polyester using the same
This invention relates to a method of producing polyesters resulting from homopolymerization or copolymerization of a 3-hydroxyalkanoic acid(s) and having biodegradability and good physical...
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7429468 |
Mutant B-type DNA polymerases exhibiting improved performance in PCR
The present invention relates to thermostable mutants of B-type DNA polymerases comprising a Y-GG/A amino acid motif between the N-terminal 3′-5′-exonuclease domain and the C-terminal...
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7427498 |
Composition, methods and reagents for the synthesis of a soluble form of human PHEX
This invention relates to a soluble form of PHEX, PHEX being a type II integral membrane glycoprotein. This enzyme is the gene product of a phosphate-regulating gene with homologies to...
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7425436 |
Covalent tethering of functional groups to proteins and substrates therefor
A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase...
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7425433 |
Carboxylic acid reductase polypeptide, nucleotide sequence encoding same and methods of use
The invention provides the nucleotide sequence and amino acid sequence for the enzyme carboxylic acid reductase isolated from bacteria. Expression cassettes, vectors, transformed cells, and...
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7425423 |
Thermostable nucleic acid polymerase from Thermococcus gorgonarius
A purified thermostable enzyme is derived from the thermophilic archaebacterium Thermococcus gorgonarius. The enzyme can be native or recombinant, retains approximately 90% of its activity after...
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7425442 |
Phytate polynucleotides and methods of use
This invention relates to newly identified polynucleotides and polypeptides in the phytic acid biosynthetic pathway, fragments, variants and derivatives of same; methods for making the...
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7425450 |
Regulatable growth of filamentous fungi
The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention...
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7425434 |
Gene encoding cyclododecanone monooxygenase
The invention relates to a new strain of Pseudomonas putida (designated as HI-70) and to the isolation, cloning, and sequencing of a cyclododecanone monooxygenase-encoding gene (named cdnB) from...
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7425435 |
Corynebacterium glutamicum genes encoding phosphoenolpyruvate: sugar phosphotransferase system proteins
Isolated nucleic acid molecules, designated PTS nucleic acid molecules, which encode novel PTS proteins from Corynebacterium glutamicum are described. The invention also provides antisense...
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7425625 |
Carotenoid ketolase genes with improved ketocarotenoid yield
Protein engineered CrtO ketolases isolated from Rhodococcus erythropolis AN12 are provided having increased carotenoid ketolase activity. Methods using the present CrtO ketolases are also...
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7422886 |
Method for determining modulation of P110Δ activity
The invention relates to a novel lipid kinase which is part of the PI3 Kinase family. PI3 Kinases catalyze the addition of phosphate to inositol generating inositol mono, di and triphosphate....
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7422873 |
Mutant carotenoid ketolase
CrtW carotenoid ketolases are provided useful for the production of astaxanthin. The ketolases genes of the present invention exhibit improved ketolase activity when converting cyclic hydroxylated...
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7422887 |
Phospholipase A2 and gene thereof
To provide a novel phospholipase A 2 (PLA 2 ) associated with psoriasis, a nucleic acid encoding the same, a method for characterizing, identifying or screening an inhibitor for the PLA 2 or a...
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7422881 |
DNAs coding for flavone synthases, methods of using flavone synthase DNAs, and plants, flowers, and vectors containing flavone synthase DNAs
DNA obtained, for example, from snapdragon or torenia , encoding an enzyme that can convert flavanones directly to flavones, and its uses; the DNA and amino acid sequences for enzymes encoded...
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