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7396670 |
Asparaginases and method of preparing a heat-treated product
The formation of acrylamide during heat treatment in the production of a food product is reduced by treating the raw material with an enzyme before the heat treatment. The enzyme is capable of...
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7396921 |
Compositions and kits for detecting a sequence mutation in cinnamyl alcohol dehydrogenase gene associated with altered lignification in loblolly pine
Loblolly pine ( Pinus taeda L.) is the most important commercial tree species in the USA harvested for pulp and solid wood products. Increasing the efficiency of chemical pulping may be achieved...
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7396666 |
Glycosyltransferase, nucleic acid encoding the glycosyltransferase and method of testing canceration using the nucleic acid
A tumor marker nucleic acid of the present invention is concerned with a nucleic acid hybridizing under stringent conditions to a nucleotide sequence described in SEQ ID NO: 1 or a complementary...
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7396669 |
Mammalian endonucleases and methods of use
Isolated mammalian Mus81-Eme endonuclease complexes comprise an Mus81 protein portion and an Eme protein portion. A method of identifying a chemical compound that modulates mammalian cellular...
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7393675 |
Corynebacterium glutamicum genes encoding proteins involved in carbon metabolism and energy production
Isolated nucleic acid molecules, designated SMP nucleic acid molecules, which encode novel SMP proteins from Corynebacterium glutamicum are described. The invention also provides antisense...
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7393671 |
Mutant carotenoid ketolases
CrtW carotenoid ketolases are provided that are useful for the production of astaxanthin and other cyclic ketocarotenoids. The mutant ketolase genes of the present invention encode polypeptides...
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7393667 |
Stereoselective reduction process for the preparation of pyrrolotriazine compounds
The invention relates to a process for the enzymatic, stereoselective reduction of ketone compounds to provide chiral alcohols, for example the compound of formula Ib:
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7393672 |
DNA coding for endo-β-galactosidase
A full-length cDNA is obtained by analyzing the partial amino acid sequence of purified endo-β-galactosidase C, constructing primers based thereon, effecting PCR with the use of the genomic DNA of...
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7393679 |
Whole cell catalyst
A whole cell catalyst is described comprising a hydantoinase, a racemase and a carbamoylase. Thus this catalyst is able to degrade hydantoins directly into the amino acids. Additionally, a process...
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7390894 |
Glutathione S-transferase sequence variants
Isolated GSTO2 nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as GSTO2 allozymes. Methods for determining if...
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7390892 |
Nucleic acids encoding novel cyclic GMP dependent protein kinases from Elmeria maxima
The present invention relates to novel protozoal cyclic GMP dependent protein kinases and genes encoding same that have been isolated from Eimeria maxima and Plasmodium falciparum . Nucleic acid...
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7390485 |
Design and therapeutic use of adpase enhanced apyrases
The present invention provides for design and therapeutic use of ADPase enhanced polypeptides, pharmaceutical compositions, and methods useful for preventing and reversing platelet aggregation and...
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7390642 |
Salutaridinol 7-O-acetyltransferase and derivatives thereof
This invention provides: (A) a protein the sequence of which is in FIG. 8 (SEQ. ID n° 14), or a fragment thereof having at least 15 amino acids, or a variant thereof, having at least 70%...
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7390643 |
Geranyl diphosphate synthase molecules, and nucleic acid molecules encoding same
In one aspect, the present invention provides isolated nucleic acid molecules that each encode a geranyl diphosphate synthase protein, wherein each isolated nucleic acid molecule hybridizes to a...
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7390891 |
Polynucleotides encoding a telomerase component TP2
Disclosed are nucleic acid molecules encoding polypeptides of the telomerase complex. Also disclosed are methods of preparing the nucleic acid molecules and polypeptides, and methods of using these...
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7387893 |
Vectors, cells and processes for pyrimidine deoxyribonucleosides production
Novel DNA constructs and host cells comprising the same are disclosed. DNA constructs comprise a transcription unit (e.g. operon) comprising DNA sequences encoding for ribonucleotide reductase and...
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7388084 |
Promoter motifs in Candida tropicalis
The present invention provides modified promoters from Candida troplicalis CYP and POX4 genes. The modified promoters have various sequence motifs added, deleted, or altered in order to modulate...
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7384787 |
Increasing perhydrolase activity in esterases and/or lipases
The invention provides for methods of modifying n esterase or a lipase enzyme to introduce perhydrolase activity or to increase the already-existing perhydrolase activity. The invention also...
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7385104 |
Plants synthesizing a modified starch, a process for the generation of the plants, their use, and the modified starch
The present invention relates to recombinant nucleic acid molecules which contain two or more nucleotide sequences which encode enzymes which participate in the starch metabolism, methods for...
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7381544 |
Nucleic acid that encodes a fusion protein
This invention provides fusion polypeptides that include a glycosyltransferase catalytic domain and a catalytic domain from an accessory enzyme that is involved in making a substrate for a...
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7381553 |
Highly active xylose reductase from Neurospora crassa
A new xylose reductase encoding gene from Neurspora crassa was heterologously expressed in E. coli as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was...
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7381554 |
UDP-N-acetylglucosamine: galactose-β1,3-N-acetylgalactosamine-α-R/N-acetylglucosamine-β1,3-N-acetylgalactosamine-α-R (GlcNAc to GalNAc) β1,6-N-acetylglucosaminyltransferase, C2/4GnT
A novel gene defining a novel human UDP-GlcNAc: Gal/Gl cNAcβ 1-3GalNAc αβ1, 6GlcNAc-transferase, termed C2/4GnT, with unique enzymatic properties is disclosed. The enzymatic activity of C2/4GnT...
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7381555 |
Lactobacillus N-deoxyribosyl transferases, corresponding nucleotide sequences and their uses
The invention concerns novel polypeptides and their fragments, isolated from Lactobacillus , having at least a N-deoxyribosyl transferase activity, the polynucleotides encoding said polypeptides,...
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7378264 |
α-amylase mutants
The present invention relates to a method of constructing a variant of a parent Termamyl-like α-amylase, which variant has α-amylase activity and at least one altered property as compared to the...
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7378512 |
Production of proteins by autoproteolytic cleavage
The present invention relates to a process for the production of a heterologous polypeptide with homogeneous N-terminus in a bacterial host cell, wherein the heterologous polypeptide is...
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7378263 |
In vivo site-specific incorporation of N-acetyl-galactosamine amino acids in eubacteria
Methods and compositions for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid having a N-acetylgalactosamine moiety into a...
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7374918 |
Modified sarcosine oxidases, genes and recombinant DNAs thereof, and methods for preparing the same
An isolated DNA molecule encoding modified sarcosine oxidases having optimal pH, high activity in the slightly acidic range and improved stability and a method for preparing the modified sarcosine...
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7374917 |
Mutant 2.5-diketo-L-gluconic acid reductases
Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated...
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7375091 |
HER-2/neu fusion proteins
The present invention is generally directed to HER-2/neu fusion proteins, nucleic acid molecules encoding HER-2/neu fusion proteins, viral vectors expressing HER-2/neu fusion proteins, and...
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7374933 |
Human metalloprotease and polynucleotides encoding the same
Novel human polynucleotide and polypeptide sequences are disclosed that can be used in thereapeutic, diagnostic, and pharmacogenomic applications.
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7375203 |
Canine cold- and menthol-sensitive receptor 1
The present invention provides nucleic acid and polypeptide sequences describing a novel canine cold- and menthol-sensitive receptor, herein named as canine CMR1 (cCMR1). The isolated nucleic acid...
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7374921 |
Cellulase tolerant to surfactants
Disclosed is a novel cellulase having an amino acid sequence in which the 162nd and/or 166th amino acid residues in the amino acid sequence of cellulase NCE5 are substituted. Further, a...
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7374923 |
Polypeptide
A screening tool and a screening method for a therapeutic agent for type II diabetes, particularly an agent for alleviating insulin resistance are disclosed. A novel polypeptide, a polynucleotide,...
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7375205 |
Elongase genes and uses thereof
The subject invention relates to the identification of several genes involved in the elongation of polyunsaturated fatty acids (i.e., “elongases”) and to uses thereof. At least two of these...
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7374922 |
Starch debranching enzymes
The invention relates to a genetically engineered variant of a parent starch debranching enzyme, i.e. a pullulanase or an isamylase, the enzyme variant having an improved thermostability at a pH in...
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7374932 |
Human kinases and polynucleotides encoding the same, and uses thereof
Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
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7374899 |
Sucrose-6-phosphate phosphatase as target for herbicides
The present invention relates to the use of a polypeptide with the biological activity of a sucrose-6-phosphate phosphatase which, if not present, brings about growth retardation symptoms and...
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7374920 |
Ginkgo biloba levopimaradiene synthase
The present invention is directed to nucleic acid sequences of Ginkgo biloba diterpene synthases, particularly of a levopimaradiene synthase. More specifically, the invention is directed to a...
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7371553 |
Chemically modified enzymes with multiple charged variants
This invention provides modified enzymes comprising one or more amino acid residues replaced by cysteine residues, where the cysteine residues are modified by replacing the thiol hydrogen in the...
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7371571 |
Recombinant mycobacteria overexpressing D-alanine ligase gene and uses therefore
Recombinant mycobacterial strains which overproduce essential biosynthetic enzymes of pathogenic mycobateria are provided. These strains overproduce enzymes involved in the synthesis and...
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7371550 |
Cholesterol oxidase stable in the presence of surfactant
A novel cholesterol oxidase having stability in the presence of surfactant and a gene encoding the novel cholesterol oxidase.
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7371552 |
Polypeptide
We disclose a food additive comprising a PS4 variant polypeptide, in which the PS4 variant polypeptide is derivable from a parent polypeptide having non-maltogenic exoamylase activity, in which the...
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7371838 |
Nucleic acids encoding β 1,4-N-acetylgalactosaminyltransferases from C. jejuni
This invention provides prokaryotic β1,4-N-acetylglucosaminyl (GalNAc) traosferases involved in synthesis of lipooligosaccharide (LOS). The β1,4-GalNAc transferases can be obtained from, for...
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7371839 |
Alkaline proteases
The present invention relates to alkaline proteases having high specific activity and strong oxidant resistance. The present invention also relates to alkaline proteases having excellent detergency...
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7371554 |
Isozymes of lacrimator component synthase and gene encoding the same
It is an object of the present invention to provide isozymes of the lachrymatory factor producing enzyme, the amino acid sequences of these isozymes and a gene that codes for these amino acid...
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7371560 |
Photosynthetic hydrogen production
A process for the production of hydrogen, comprising the steps of: (i) providing a photosynthetic microorganism having electron transfer capability through a photosynthetic light reaction pathway...
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7371558 |
Process for the biological production of 1,3-propanediol with high yield
The present invention provides a microorganism useful for biologically producing 1,3-propanediol from a fermentable carbon source at higher yield than was previously known. The complexity of the...
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7371548 |
Avermectin aglycon synthase genes
The present invention relates to an isolated DNA which comprises a DNA sequence encoding avermectin aglycon synthase domains that corresponds to multifunctional enzyme proteins involved in the...
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7371547 |
Process for producing vitamin B6
Disclosed is a mutant of a recombinant microorganism of the genus Sinorhizobium capable of producing vitamin B 6 having a recombinant plasmid with pdxJ gene that acquired histidine requirement...
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7371546 |
Glucoamylase variants
The invention relates to a variant of a parental fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
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