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7390944 |
Inbred corn line G06-NP2739
Broadly this invention provides an invention which is an inbred corn line G06-NP2739. The methods for producing a corn plant by crossing the inbred line G06-NP2739 are also encompassed by the...
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7390943 |
Inbred corn line G06-NP2598
Basically, this invention provides for an inbred corn line designated G06-NP2598, methods for producing a corn plant by crossing plants of the inbred line G06-NP2598 with plants of another corn...
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7390894 |
Glutathione S-transferase sequence variants
Isolated GSTO2 nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as GSTO2 allozymes. Methods for determining if...
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7390892 |
Nucleic acids encoding novel cyclic GMP dependent protein kinases from Elmeria maxima
The present invention relates to novel protozoal cyclic GMP dependent protein kinases and genes encoding same that have been isolated from Eimeria maxima and Plasmodium falciparum . Nucleic acid...
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7390890 |
Inhibitors of nucleoside metabolism
The present invention provides compounds having the formula:
wherein A is CH or N; B is chosen from OH, NH 2 , NHR, H or halogen; D is chosen from OH, NH 2 , NHR, H, halogen or SCH 3 ; R is an...
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7390832 |
Dinuclear copper-based compound and ligand for nucleic acid scission and anticancer treatment
The present invention is related to a novel method for oxidizing or splitting nucleic acids at specific points on a complementary nucleic acid segment using a dinuclear copper-based compound of...
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7390782 |
Methods and products related to metabolic interactions in disease
The invention involves methods of regulating cell growth and division to control disease processes by manipulating mitochondrial metabolism and the expression of cell surface immune proteins. The...
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7390780 |
Gene delivery mediated by liposome-DNA complex with cleavable peg surface modification
A liposome composition and method for delivery of a nucleic acid in vivo or ex vivo is described. The liposomes in the composition are comprised of (i) a cationic lipid and (ii) a lipid joined to a...
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7390661 |
Artificial bidirectional promoter for activation of gene expression
A bidirectional module for activation of gene expression and regulation of transcription in both directions is disclosed. The bidirectional module comprises multiple cis regulatory DNA sequence...
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7390640 |
Circular permutant GFP insertion folding reporters
Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The...
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7390637 |
Keratinocyte derived interferon
The present invention relates to a novel KDI protein which is a member of the interferon family. In particular, isolated nucleic acid molecules are provided encoding a human interferon polypeptide,...
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7390632 |
Soluble ErbB3 receptor isoforms
The present invention discloses a system and method using the human ErbB3 receptor, p85-sErbB3, as a negative regulator of heregulin-stimulated ErbB2, ErbB3, and ErbB4 activation. The present...
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7390619 |
Optimization of immunomodulatory properties of genetic vaccines
This invention provides methods for obtaining molecules that can modulate an immune response, and immunomodulatory molecules obtained using the methods. The molecules find use, for example, in the...
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7388137 |
Inbred corn line PH714
A novel inbred maize line designated PH714 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing inbred maize line PH714 with another maize plant....
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7388093 |
Gene for identifying individuals with familial dysautonomia
This invention relates to methods and compositions useful for detecting mutations which cause Familial Dysautonomia. Familial dysautonomia (FD; Riley-Day syndrome), an Ashkenazi Jewish disorder, is...
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7388089 |
Anti-arthropod vector vaccines method of selecting and uses thereof
The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent...
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7388087 |
Enhancement of immune response to vaccine by interferon alpha
Exogenous cDNA capable of expressing interferon α activity, exogenous interferon α protein, inducers of endogenous interferon α protein activity, inducers of endogenous interferon β protein...
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7388086 |
NPHS2 gene involved in the steroid-resistant nephrotic syndrome, protein encoded by said gene and diagnostic and therapeutic uses
The invention concerns a novel gene, called NPHS2 gene coding for a protein involved in the cortico-resistant nephrotic syndrome, and diagnostic and therapeutic uses of the novel identified...
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7388084 |
Promoter motifs in Candida tropicalis
The present invention provides modified promoters from Candida troplicalis CYP and POX4 genes. The modified promoters have various sequence motifs added, deleted, or altered in order to modulate...
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7387887 |
Nucleic acid melting analysis with saturation dyes
Methods are provided for nucleic acid analysis wherein a target nucleic acid is mixed with a dsDNA binding dye to form a mixture. Optionally, an unlabeled probe is included in the mixture. A...
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7387877 |
Bio-sensor and bio-sensor reporting system
A biosensor unit that can be wall mounted in a location to perform testing of ambient air for bio-contaminants. This unit could contain an air filter for collecting contaminants and a...
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7387876 |
Amplification of trace amounts of nucleic acids
Methods of reducing background during amplification of small amounts of nucleic acids employ careful analysis of sources of low level contamination. Ultraviolet light can be used to reduce nucleic...
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7387875 |
Methods for monitoring multiple gene expression
The present invention relates to methods for monitoring differential expression of a plurality of genes in a first filamentous fungal cell relative to expression of the same genes in one or more...
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7385053 |
Functionalized compositions for improved immobilization
The present invention relates to improved covalent coupling of two or more entities such as biomolecules, polymer compositions, organic/inorganic molecules/materials, and the like, including their...
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7385045 |
Canine B7-1 nucleic acid molecules
The present invention relates to B7 proteins; to B7 nucleic acid molecules, including those that encode such B7 proteins; to antibodies raised against such B7 proteins; and to therapeutic compounds...
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7385044 |
Isolated peptides which bind to MHC Class II molecules, and uses thereof
Peptides which have an amino acid sequence identical to sequences found in tumor rejection antigen precursors, such as NY-ESO-1, and SSX-2, are disclosed. These peptides bind to MHC-Class II...
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7385043 |
Homogeneous multiplex screening assays and kits
Highly multiplexed homogeneous in vitro screening assays for numerous possible nucleic acid targets, any of which might be present in a sample, utilize fluorescent hybridization probes that are...
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7384768 |
Nucleic acids and polypeptides specific for pathogenic strains of the Neisseria genus
The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
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7384749 |
Electrodes linked via conductive oligomers to nucleic acids
The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids...
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7384746 |
Charge tags and the separation of nucleic acid molecules
The present invention relates to novel phosphoramidites, including positive and neutrally charged compounds. The present invention also provides charge tags for attachment to materials including...
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7384737 |
Synthesis of spatially addressed molecular arrays
Methods are disclosed for forming spatially addressable arrays of polynucleotides of known squence, by using blocking groups that prevent the incorporation of multiple nucleotides during each...
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7384638 |
Compounds and methods for treatment and diagnosis of Chlamydial infection
Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia ...
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RE40374 |
Canine IL-13 immunoregulatory proteins and uses thereof
The present invention relates to canine interleukin-4, canine or feline Flt-3 ligand, canine or feline CD40, canine or feline CD154, canine interleukin-5, canine interleukin-13, feline interferon...
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7381819 |
Composition for treatment or prevention of endometrial cancer and method of preventing or treating endometrial cancer using the composition
Provided are a composition for the treatment or prevention of an endometrial cancer including a nuclear acid molecule inducing RNA interference against human syndecan-1 gene expression and a...
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7381813 |
Nucleic acids encoding estrogen receptor ligand binding domain variants
Mutants of steroid receptor ligand binding domains and synthetic ligands which have specific binding affinities for these receptors are provided. The use of these LBD-ligand combinations for...
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7381811 |
Compositions and methods for detecting Trichomonas vaginalis in a sample
The present invention relates to oligonucleotides useful for determining the presence of Trichomonas vaginalis in a test sample. The oligonucleotides of the present invention may be incorporated...
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7381810 |
Polyphenol oxidase genes from lettuce
The present invention provides genetic sequences encoding polyphenol oxidase enzymes of lettuce, banana, tobacco and pineapple plants, and recombinant vectors comprising same, and methods of...
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7381809 |
Compositions and methods for the treatment of immune related diseases
The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
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7381808 |
Method and nucleic acids for the differentiation of prostate tumors
The present invention relates to chemically modified genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method...
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7381708 |
Suppression of eIF5A1 expression by the use of antisense oligonucleotides for the prevention of retinal cell death in the glaucomatous eye
The present invention provides methods for preventing retinal ganglion cell death in the glaucomatous eye and methods for suppressing apoptosis-specific eIF5A1 expression through the use of...
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7381548 |
Method for producing L-amino acid using bacterium of Enterobacteriaceae family having expression of yafA gene attenuated
The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea ,...
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7381543 |
TAB1 protein and DNA coding therefore
TAB1 protein having activity which activates factor TAK1 in the TGF-β signaling pathway, and having the amino acid sequence shown in FIG. 1.
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7381542 |
Nucleic acids encoding a biogenic amine receptor
The present invention relates to novel mammalian biogenic amine receptor proteins and genes that encode such proteins. The invention is directed toward the isolation and characterization of...
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7381533 |
Electrodes linked via oligomers to nucleic acids
The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids...
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7381532 |
Compositions and methods for the detection of a nucleic acid using a cleavage reaction
The invention relates to a method of generating a signal indicative of the presence of a target nucleic acid sequence in a sample, where the method includes forming a cleavage structure by...
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7381526 |
Assays for drug discovery based on microcompetition with a foreign polynucleotide
A recent discovery showed that microcompetition between a foreign polynucleotide and a cellular polynucleotide is a risk factor for some of the major chronic diseases. The invention uses this novel...
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7381525 |
AC/DC voltage apparatus for detection of nucleic acids
The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids...
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7378517 |
UV excitable energy transfer reagents
Novel energy transfer dyes which can be used with shorter wavelength light sources are provided. These dyes include a donor dye with an absorption maxima at a wavelength between about 250 to 450 nm...
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7378510 |
Synthetic zinc finger protein encoding sequences and methods of producing the same
The invention relates to nucleic acids encoding synthetic zinc finger proteins for gene regulation in plants. The invention also relates to methods of producing synthetic zinc finger protein in...
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7378509 |
NF-kappaB oligonucleotide decoy molecules
The present invention concerns double-stranded NF-κB decoy oligodeoxynucleotide (NF-κB dsODN) molecules that contain a core sequence capable of specific binding to an NF-κB transcription factor....
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