|
Match
|
Document |
Document Title |
|
|
4683298 |
Process for the preparation of aminated polysaccharide derivatives
A process for preparing an amino deoxy derivative of a polysaccharide. The process comprises oxidizing the polysaccharide with dimethyl sulfoxide in combination with acetic anhydride or acetic...
|
|
|
4680285 |
Treatment of malignant tumors with 2-(β-D-ribofuranosylthiazole-4-carboxamide related compounds
The compound 2-β-D-ribofuranosylthiazole-4-carboxamide is used to treat malignant tumors in warm blooded animals. Esters of this compound such as...
|
|
|
4673666 |
2-amino-3-ethoxycarbonylamino-6-(p-fluoro-benzylamino)-pyridine gluconate and pharmaceutical preparations containing it
There is disclosed 2-amino-3-ethoxycarbonylamino-6-(p-fluoro-benzylamino)-pyrid
ine gluconate, process for its production and pharmaceutical preparations which contain this material.
|
|
|
4661474 |
2',3'-dideoxy-2'-fluorokanamycin A and 1-N-(α-hydroxy-ω-aminoalkanoyl) derivatives thereof
New compounds, 2',3'-dideoxy-2'-fluorokanamycin A and 1-N-(α-hydroxy-ω-aminoalkanoyl) derivatives thereof, particularly 1-N-(DL- or L-3-amino-2-hydroxypropionyl)- and...
|
|
|
4656159 |
Galactose-C-6 nitrogen mustard compounds and their uses
Compounds of the formula ##STR1## wherein X is halogen; each R independently represents H, a C 1 -C 4 alkyl group, a C 2 -C 4 alkanoyl group, a phosphate group, or a sulfate, sulfonate, or...
|
|
|
4656260 |
Cyclic pyrazolo C-nucleoside compound and process for preparing the same
A novel compound, 3-(β-D-ribofranosyl)pyrazolo-[3,4-e] [1,3]oxazine-5,7-dione, exhibiting a function of inhibiting propagation or growth of various virus, and a process for preparing the same.
|
|
|
4650862 |
Sugar phosphates
Sugar phosphate of the following general formula (I): ##STR1## is prepared by reaction between a phosphoric monoester and a glycidyltriammonium salt. The sugar phosphate according to the invention...
|
|
|
4639436 |
Antidiabetic 3,4,5-trihydroxypiperidines
The invention includes certain 3,4,5-trihydroxypiperidine compounds, methods for their preparation, compositions containing said 3,4,5-trihydroxypiperidine compounds and methods for the use of said...
|
|
|
4632917 |
Pseudooligosaccharides with an α-glucosidase-inhibiting action, their use and pharmaceutical products
Pseudooligosaccharides of the formula I ##STR1## in which l, m and n have the meanings given, physiologically acceptable salts thereof with acids, a process for their preparation, pharmaceutical...
|
|
|
4631271 |
Serotonin-D-fructose and pharmaceutical composition containing same
The invention relates to new serotonin derivatives which form strong reducing agents. They can be represented by the formula: ##STR1## in which R represents a hydrogen atom or a hydroxyl group, and...
|
|
|
4631272 |
N-acylated 1-alkylamino-1-deoxy-ketose derivatives, a process for their preparation and their use
Compounds of the formula ##STR1## in which R 1 represents hydrogen or an optionally substituted, straight-chain or branched alkyl or mono- or poly-unsaturated alkenyl radical with in each case up...
|
|
|
4629699 |
Process for the preparation of oligosaccharide fractions by degradation of heparin
Process for the preparation of oligosaccharides and oligosaccharide fractions by degradation of heparin, which comprises submitting to incubation an aqueous solution of heparin containing from 5 to...
|
|
|
4619996 |
Process for preparing 2-β-D-ribofuranosylselenazole-4-carboxamide
A chemical process for preparing 2-β-D-ribofuranosylselenazole-4-carboxamide, comprises reacting 2,3,5-tri-O-benzoyl-β-D-ribofuranosyl-1-carbonitrile with gaseous hydrogen selenide in a polar...
|
|
|
4618602 |
Amine containing pseudooligosaccharide, pharmaceutical composition and method of use
Pseudooligosaccharide of the formula I ##STR1## and physiologically acceptable salts thereof with acids, a process for the preparation, pharmaceutical products and the use are described. The...
|
|
|
RE32268 |
Therapeutic composition and method of therapeutically treating warm blooded animals therewith
The invention provides a novel therapeutic composition comprising a pharmaceutically acceptable carrier containing a therapeutically effective amount of an ethereally monosubstituted monosaccharide...
|
|
|
4613590 |
Amino D-manno-2-octulopyranosidonate containing compounds, pharmaceutical compositions and method of use
Aminodeoxy derivatives of 3-deoxy-D-manno-2-octulosonic acid (KDO) are potent inhibitors of bacterial enzymes and a novel class of antibacterial agents.
|
|
|
4613589 |
D-manno-2-octulosonic acid derivatives, pharmaceutical compositions and method of use
Derivatives of 3-deoxy-D-manno-2-octulosonic acid (KDO) are potent inhibitors of bacterial enzymes and a novel class of antibacterial agents.
|
|
|
4611058 |
Process for the preparation of 1,5-didesoxy-1,5-imino-D-glucitol and N-derivatives thereof
The invention relates to a process for preparing 1,5-didesoxy-1,5-imino-D-glucitol (desoxynojirimicin) and N-derivative thereof, which are known to be powerful inhibitors for α-glycosidases. The...
|
|
|
4600771 |
Process for the preparation of acylated sugars with a glycosidically bonded isothiocyanate group
Acylated sugars with a glycosidically bonded isothiocyanate group are prepared by reacting acylated sugars with a glycosidically bonded halogen atom with thiocyanates in the presence of a phase...
|
|
|
4596794 |
Method for the treatment of hyperglycemia, hyperlipemia, inflammatory diseases, pains or pyrexia due to the accentuation of central nerve, or tumor
Disclosed is a method for the treatment of hyperglycemia, hyperlipemia, inflammatory diseases, pains due to the accentuation of central nerve, pyrexia due to the accentuation of central nerve or...
|
|
|
4595678 |
N-substituted pseudo-aminosugars and pharmaceutical compositions containing same
A compound of the general formula: ##STR1## wherein A is hydrogen or a hydroxyl group; B is (1) a group of the formula; ##STR2## (2) a group of the formula; ##STR3## or (3) a group of the formula;...
|
|
|
4587331 |
Platinum complexes of polyhydroxylated alkylamines and 2-polyhydroxylated alkyl-1,2-diaminoethanes
Platinum complexes of polyhydroxylated alkylamines and 2-polyhydroxylated alkyl-1,2-diaminoethanes useful for inducing regression and/or palliation of cancer diseases in mammals.
|
|
|
RE32095 |
Cooked flavors for smoking products
Reducing sugars are reacted with ammonium hydroxide or ammonium salts in the presence of a trace amount of certain amino acids to produce reaction flavors for use in smoking compositions and...
|
|
|
4574122 |
Substituted O-acylglycosylamides, pharmaceutical compositions and method of use
Compounds of the formula ##STR1## in which X is hydrogen or the radical --CH 2 OR 5 , three of R 2 , R 3 , R 4 and R 5 each independently is hydrogen or ##STR2## and the fourth is ##STR3## Z...
|
|
|
4565863 |
Retinoid carbohydrates
The novel retinoids of the formula ##STR1## wherein R represents a residue of a sugar attached ester-wise or a residue of an amino-sugar attached amide-wise or of derivatives of such sugars and n...
|
|
|
4563421 |
Method for determining the presence of endohydrolase in a liquid and composition therefor
What are disclosed are polysaccharide derivatives of the formula ##STR1## in which n denotes a number from 100 to 12,500 and R denotes hydrogen, a carboxyalkyl or hydroxyalkyl group with 1 to 5...
|
|
|
4520191 |
Paulomycin derivatives
Novel and useful compounds are obtained by the degradation of antibiotics paulomycin A and paulomycin B. These novel compounds are useful as ultraviolet light filters in plastics, cloth, and the like.
|
|
|
4514561 |
Process for preparing α-L N-acetyl daunosaminide
The present invention is a unique method for the regioselective addition of a functional group to an allylic alcohol moiety which is particularly useful in the preparation of cis-hydroxyamino sugars.
|
|
|
4508892 |
Compositions for competitive protein binding assays inhibiting non-specific interference
Conjugates of heavy atoms containing analytes or their analogs and fluorescent molecules are covalently bonded to macromolecular supports to minimize the interference of fluorescence during assays,...
|
|
|
4504655 |
Substances potentiating the activity of antibiotics and their production
Novel compound having the formula and salts thereof: ##STR1## wherein R 1 is NHCH 2 CH 2 SO 3 H or OH and R 2 is SO 3 H or H, which potentiate the antibacterial activity of β-lactam...
|
|
|
4491660 |
Matrix polymers for binding endotoxins
An endotoxin binding material affixed to a support is disclosed. One embodiment is a matrix material capable of binding endotoxins and comprising a polar, water-insoluble, high molecular weight...
|
|
|
4491659 |
2,6-Didioxy-3-amine,4-carboxy methylglycoside and related compounds
Disclosed is a chiral, total synthesis of thienamycin from D-glucose which proceeds via intermediates I, II, III and IV to known lactone V which is known to be useful via acid VI in the total...
|
|
|
4481196 |
Glycoside phosphate derivatives, pharmaceutical composition of the same and method of use
New phosphate derivatives represented by the formula: ##STR1## wherein R 1 , R 2 , and R 3 are each hydroxy, alkoxy, alkanoylamino or protected hydroxy; A is lower alkylene; R 4 is...
|
|
|
4477443 |
Tylosin derivatives, their preparation and pharmaceutical compositions containing them
Tylosin compounds of the formula ##STR1## wherein R 1 represents a hydroxyl group; a halogen atom; ##STR2## group (wherein R 5 is a hydrogen atom or a lower alkyl group which may be substituted...
|
|
|
4450156 |
Pharmaceutical composition containing a derivative of ortho-aminobenzoic acid as an active ingredient
Disclosed is a pharmaceutical composition containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: ##STR1## wherein 1 R denotes one member...
|
|
|
4439414 |
1-.sup.11 C-D-Glucose and related compounds
The novel compounds 1- 11 C-D-glucose, 1- 11 C-D-mannose, 1- 11 C-D-galactose, 2- 11 C-D-glucose, 2- 11 C-D-mannose and 2- 11 C-D-galactose which can be used in nuclear medicine to monitor...
|
|
|
4401758 |
Process for making oligosaccharides having anti-Xa activity and the resulting oligosaccharides
Oligosaccharides obtainable from heparin including heparinic constituents of molecular weights ranging from 2000 to 50,000. Said fractions have a Yin-Wessler titer and a USP titer in a ratio of at...
|
|
|
4386026 |
Cell-specific glycopeptide ligands
Cell-specific ligands comprising conjugates of saccharides and amino acids or peptides are synthesized from amino acids such as ornithine, lysine, peptides such as dilysine, diornithine or...
|
|
|
4374832 |
Modulators of the complement system comprising polyhexaose arylene sulfate derivatives
Poly-cation salts of bis- (or tris-) (polyhexaose-oxy)-arylene sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such...
|
|
|
4374831 |
Modulators of the complement system comprising bis-glucopyranosyl arylene sulfate derivatives
Bis-(β-D-glucopyranosyl-1-oxy)-arylene sulfate derivatives, the cation salts thereof, useful as modulators of the complement system, the intermediates thereof and the process for the preparation...
|
|
|
4362720 |
Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals
O-acetylated glycals react with ceric ammonium nitrate in the presence of sodium azide to provide, in good yield, O-acetylated 2-azido-2-deoxy glycosyl nitrates. These nitrates can be used to...
|
|
|
4359460 |
6'-(1-Adamanta necarboxylate)-6-O-α-D-galactopyranosyl-α-D-glucopyranose sulfate salts
6'-(1-Adamantanecarboxylate)-6-O-α-D-galactopyranosyl-α-D-
gluco pyranose sulfate salts, useful as complement inhibitors, and the process for making such compounds.
|
|
|
4359461 |
Mono-, di- and tri-adamantylcarbonyl- digalactopyranosyl- glucopyranosyl- fructofuranose sulfate salts
Mono-, di- and tri-adamantylcarbonyl- digalactopyranosyl- glucopyranosyl- fructofuranose sulfate salts, useful as complement inhibitors and the process of making such compounds.
|
|
|
4357323 |
Polysaccharide RBS substance and antitumor agent containing same
A polysaccharide RBS substance having the ultraviolet absorption spectrum depicted in FIG. 1 and the infrared absorption spectrum depicited in FIG. 2 is obtained from rice bran by extraction with...
|
|
|
4350811 |
Chiral sugar complexes
Chiral Schiff bases according to the general formula: ##STR1## and chiral transition metal complexes thereof, wherein at least the carbon atom of the monosaccharide to which the iminyl nitrogen...
|
|
|
4322523 |
Methylolated mono- and oligosaccharides
This invention is directed to a derivative of a reducing sugar, said reducing sugar having molecular weights of from 120 to 2000, in that said derivative having at least one methylol group which...
|
|
|
4321364 |
Preparation of soluble chromogenic substrates
A chromogenic substrate for the assay of polysaccharide endo-hydrolases is the reaction product of a polysaccharide susceptible to endo-hydrolase degradation, a chemical reagent for increasing the...
|
|
|
4316894 |
Antibiotic SF-1130-x.sub.3 3 substance and production and use thereof
A new antibiotic SF-1130-x 3 substance is produced by cultivating a microorganism Streptomyces myxogenes SF-1130 (deposited under FERM-P. 676 and ATCC 31305) in a liquid culture medium under...
|
|
|
4315921 |
Pharmaceutical composition containing fara-amino-benzoic acid-N-D-xyloside as an active ingredient
Disclosed is a pharmaceutical composition containing p-aminobenzoic acid-N-D-xyloside or a pharmaceutically acceptable salt thereof as an active ingredient.
|
|
|
4303786 |
Isonitrile derivatives of macromolecules containing hydroxyl groups
The present invention relates to novel isocyano derivatives of linear or cross-linked, natural or synthetic macromolecules, the derivatives being of the general formula P--O--Q--NC, wherein P is...
|