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7365174 Azalide and azalactam derivatives and method for producing the same  
Compounds represented by the general formula (1) or pharmaceutically acceptable salts thereof, effective in the prevention and/or treatment of infections with microbes: (1) (a) wherein R 1 is...
7074907 Compound, process for producing the same and use thereof  
The compound of the present invention is a component originated from a natural material, camu camu ( Myrciaria dubia ), has strong antioxidative activity and stable whitening effect, and is...
6987182 Process for producing cold-gelling hydrocolloids  
A dry hydrocolloid powder with cold-gel capabilities is produced by: dissolving a hydrocolloid comprising polysaccharide chains in an aqueous solution; heating the dissolved hydrocolloid solution...
6916920 Process for producing hydrazinomonosaccharide derivatives and use thereof  
A process for producing hydrazinomonosaccharide derivatives and use of hydrazines in determining the structures of aldose and ketose monosaccharides located at the reducing ends of saccharides.
6875746 Anticancer anthraquinones and method of use thereof  
Anthraquinones are described which have anticancer or antitumor activity and which are useful for inhibiting cancer cells and cells comprising tumors in vitro or in vivo. Preferably, the...
6864241 Amine salt of lignan compounds  
The present invention provides an amine salt of a lignan compound, i.e.,...
6838450 Drug complex  
A drug complex characterized in that a residue of a drug compound such as antineoplastic agents and a carboxy(C 1-4 )alkyldextran polyalcohol obtained by treating a dextran under conditions that...
6818657 Bioprecursors of a retinoic derivative and pharmaceutical and/or cosmetic compositions  
The present invention relates to a ternary glucosyl complex which is a bioprecursor of at least one retinoic active ingredient for percutaneous application, having formula (I), wherein E represents...
6800742 Method for producing β-D-ribofuranose derivatives or optical isomers thereof  
The present invention provides a method for efficiently producing β-D-ribofuranose derivatives or optical isomers thereof, useful as synthetic intermediates of pharmaceutical nucleic acid-series...
6693085 Macrolide compound JK  
Compound JK represented by the general formula (1): wherein R is H or —CH 3 ; or a pharmaceutically acceptable salt thereof. Compound JK has an excellent antimicrobial activity even against...
6664235 Medicaments comprising sialic acid derivatives as active ingredients  
A medicament for treatment of a viral infection which comprises as an active ingredient a compound represented by the following formula (I) or its Pharmaceutically acceptable salt, or a hydrate...
6649172 Amphipathic aldehydes and their uses as adjuvants and immunoeffectors  
This invention relates to novel aldehyde containing compounds and their uses as adjuvants and immunoeffectors.
6624317 Taxoid conjugates as antimitotic and antitumor agents  
Compounds according to formula I: T 1 —L—T 2 (I), wherein T 1 is a taxoid group, preferably of Formula II: wherein R 1 is C 6 H 5 ; R 2 is O; L is a linking group; and T 2 is a...
6610835 Sphingolipid derivatives and their methods of use  
Derivatives of sphingolipids of the formula: are provided wherein the substituents are as defined in the specification and wherein there is at least one R 2 substituent in the sphingolipid...
6534637 Synthesis of chlorophenol red glucuronic acid  
This invention provides β-D-Glucuronidase substrates of the formula: wherein R 1 , R 2 , and R 7 -R 12 are independently selected from the group consisting of: hydrogen, fluorine, chlorine,...
6531582 2-O-(9z,12z-octadecadienoyl)-3-O-&lsqb α-D-galactopyranosyl-(1″-6′)-O-α-D-galactopyranosyl&rsqb glycerol and pharmaceutical composition containing the same  
The present invention relates to the novel compound 2-O-(9z,12z-octadecadienoyl)-3-O-[α-D-galactopyranosyl-(1 -6′)-O-α-D-galactopyranosyl]glycerol (Generic name: shinbarometin) having the...
6498269 Method for the oxidation of aldehydes, hemiacetals and primary alcohols  
A method for the oxidation of substrates comprising treating an aqueous, basic solution of a substrate having an oxidizable functionality using an elemental halogen as terminal oxidant in the...
6476204 Dextran-maleic acid monoesters and hydrogels based thereon  
Biodegradable hydrogels are formed by photocrosslinking dextran-maleic acid monoesters in which the average degree of substitution of each glucose unit of each α-D-glucopyranosyl of dextran by...
6455512 Water-soluble esterified hydrocolloids  
Emulsifiers based on the reaction product of hydrocolloid and dicarboxylic anhydrides, especially useful in the preparation of oil-in-water emulsions.
6436912 Drug complexes  
A drug complex characterized in that a residue of a drug compound such as antineoplastic agents and a carboxy(C 1-4 )alkyldextran polyalcohol obtained by treating a dextran under conditions that...
6384201 Synthetic method for the preparation of the antineoplastic agent etoposide  
A synthetic method for the preparation of the anti-tumor drug Etoposide. In one embodiment, the method includes the direct condensation of 4′-demethyl-epipodophylloxin with...
6329377 Ketomethylene group-containing cysteine and serine protease inhibitors  
The present invention is directed to novel ketomethylene group-containing inhibitors of cysteine or serine proteases. Methods for the use of the protease inhibitors are also described.
6174863 Carbohydrate derivatives  
The invention relates to a carbohydrate derivative having formula I ##STR1## wherein R 1 is (1-4C)alkoxy; R 2 , R 3 and R 4 are independently (1-4C)alkoxy or OSO 3 - , the total number of...
6121430 Regiospecific synthesis of glucose-based surfactants  
New glucose-based surfactants and methods of their synthesis are described. The surfactants are synthesized through the preparation of an intermediate glucose 4,6-cyclic sulfate. The surfactants...
6030951 Chrysomycin derivative compounds and use as antitumor agents  
Disclosed are the novel C-glycoside compounds Mer-1020dA, Mer-1020dB, Mer-1020dC and Mer-1020dD which have a chromophore group in common with well-known chrysomycins A and B, but can be...
6018033 Hydrophilic, hydrophobic, and thermoreversible saccharide gels and forms, and methods for producing same  
Polymerizable saccharide monomers are made by the reaction of a saccharose and a (meth)acrylate. Hydrophilic, hydrophobic and thermoreversible gels and foams are formed upon polymerization of the...
5919768 Di- and trivalent small molecule selectin inhibitors  
The present invention provides compounds having structure (II), and the pharmaceutically acceptable salts, esters, amides and prodrugs thereof.
5869460 Sulfated and phosphated saccharide derivatives, process for the preparation of the same and use thereof  
There are described sulfated and phosphated saccharide erivatives of the Formula ##STR1## wherein R 1 is hydrogen atom or a residue of sulfate, phosphate or L-fucose; R 2 , R 3 and R 4 are...
5817800 Inhibitors of β-glucuronidase and their use in the treatment of carcinamatosis and inflammation  
Compounds of the formulae I and II ##STR1## are suitable for the suppression of tumor growth and of tumor metastasis.
5783678 Acrylic ester derivative and producing of the same and acrylic-ester-based polymer  
An acrylic ester derivative expressed by Formula (1) below is produced by reacting an acrylic ester expressed by Formula (2) below with a saccharide containing a hemiacetal hydroxyl group expressed...
5767094 Propiophenone derivative and processes for preparing the same  
A propiophenone derivative the formula I!: ##STR1## wherein R' is a lower alkanoyl group and R" is a hydrogen atom, or R' is a hydrogen atom and R" is a lower alkoxycarbonyl group, or a...
5753631 Intercellular adhesion mediators  
The present invention is directed towards compositions and methods for reducing or controlling inflammation and for treating inflammatory disease processes and other pathological conditions...
5741476 Polyhydric phenol compounds  
The invention relates to polyhydric phenol compounds of the general formula ##STR1## wherein R is a hydrogen atom or a saccharide moiety; A and B are hydrogen atoms or form together a C--C bond;...
5733892 Metastasis inhibitor composition comprising a phospholipid-linked glycosaminoglycan and method for inhibiting metastasis employing the same  
This invention relates to compounds prepared by linking glycosaminoglycan to phospholipid or lipid, which are expected to exert a pharmacological effect for inhibiting metastasis because of their...
5686586 Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same  
A polycyclic aromatic compound having the formula ##STR1## and its salts have useful therapeutic and cosmetic action particularly in psoriasis. In the formula, X represents --CHCH--, O or S, ...
5679769 Synthesis of asparagine-linked glycopeptides on a polymeric solid support  
The present invention provides a process for synthesizing a glycopeptide having the structure: ##STR1## wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are each independently H, OH, OR 1...
5668261 Process for preparing carboxylates of alkylpolyglucosides  
A process for preparing carboxylates of polyoxyalkylene siloxanes and -amines, alkylpolyoxyalkylenes, polyoxyalkylene block polymers, alkylamidepolyoxyalkylenes and alkylpolyglucosides comprising...
5652346 Dicarboxylic acid oxidation products  
What is disclosed is a dicarboxylic acid oxidation product of a immunologically reactive mono- or a polysaccharide having vicinal diols.
5648474 Crystalline etoposide 4'-phosphate diethanolate  
The present invention provides temperature stable crystalline etoposide 4'-phosphate diethanol solvate, and a process for its preparation.
5648402 Contact lenses from highly permeable siloxane polyol material  
The present invention provides soft contact lenses adopted for placement over the cornea or in the eye which have a high oxygen permeability, a low water content and excellent mechanical...
5644042 Process for production of aldobionic acid amide  
A process for the preparation of aldobionamides directly from an aldobionic acid starting material, in which an aldobionic acid is reacted by removing water by azeotropic distillation to obtain an...
5643885 Etoposide derivatives, process for preparing them, their use as a medicinal product and their use for the preparation of a medicinal product intended for anti-cancer treatment  
Compound of the formula (I) in which R' is a hydrogen atom or a radical R and R is an acyl residue. The invention also concerns the use of said compounds in the treatment of cancer and...
RE35524 Epipodophyllotoxin glucoside 4'-phosphate derivatives  
Phosphate derivatives of 4'-demethylepipodophyllotoxin glucosides are novel antitumor agents and the salts thereof offer the pharmaceutical advantage of high water solubility.
5625044 Methods for the preparation of pure homologous series of mono to tetra fatty acyl esters of sugars and pharmaceutical formulations useful in the treatment of cancer  
The present invention relates to a method for the making pure homologous series of fatty acyl esters of sugars. The production mono- to tetrapalmitates of maltose is particularly examplified....
5620961 Fructose ester-β-cyclodextrin complexes and processes for making and using same  
A specialized derivative of fructose in which the compound is a fructose ester complexed with β-cyclodextrin. Preferably, the fructose derivative is fructosehexanoate β-cyclodextrin complex, and...
5606039 Etoposide phosphate and preparative intermediates  
An etoposide phosphate represented by the formula (1): ##STR1## is prepared by blocking the hydroxyl groups of the saccharide moiety of etoposide with halogenoacetyl groups, thereafter...
5585473 Compounds and methods for monosaccharide analysis  
Compounds and methods are provided for use in monosaccharide analysis. The present invention discloses hydrazino monosaccharide derivatives. Methods for preparing and using hydrazino monosaccharide...
5580857 Use of gibberellins for the treatment of prostatitis  
The use of active gibberellins for the preparation of a pharmaceutical composition for the treatment of prostatitis. The method results in a decrease in prostate mass.
5567683 Substituted lactose and lactosamine derivatives as cell adhesion inhibitors  
Simple lactose or lactosamine related compounds which behave as ligands for the ELAM-1 and related receptors are described. These compounds are useful in the treatment of conditions characterized...
5563250 Cleavable conjugates for the delivery and release of agents in native form  
The present invention provides cleavable conjugates whose linkers contain a labile bond that is cleavable under a variety of mild conditions, including weakly acidic. Since the agent may be bonded...
Matches 1 - 50 out of 199 1 2 3 4 >