|
Match
|
Document |
Document Title |
|
|
7618946 |
Analgesic compounds, extracts containing same and methods of preparation
Various compounds obtained from plants of the Barringtonia species which are derived from Barringtoside A and Barringtoside C as precursor compounds which especially have an arabinopyranosyl...
|
|
|
7576064 |
Pyrazole derivative, drug composition containing the same and production intermediate therefor
The present invention provides pyrazole derivatives represented by the general formula:
wherein R 1 represents H, an optionally substituted C 1-6 alkyl, etc.; one of Q and T represents a...
|
|
|
7576063 |
Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same
The present invention provides pyrazole derivatives represented by the general formula:
wherein R 1 represents H, an optionally substituted C 1-6 alkyl group etc.; one of Q and T represents a...
|
|
|
7569686 |
Compounds and methods for synthesis of bicyclic nucleic acid analogs
The present invention provides compounds and methods of using them for preparing bicyclic nucleosides. The bicyclic nucleosides are useful for preparing chemically modified oligomeric compounds....
|
|
|
7556967 |
Foldable polymers as probes
Disclosed herein are novel probes, which can be used to detect and identify target molecules of interest in a sample. The disclosed probes can be used to monitor conformational changes induced by...
|
|
|
7524824 |
Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
This invention provides compositions, methods and process of producing extracts from Xanthoceras sorbifolia . The extract comprises alkaloids, coumarins, saccharides, proteins, polysaccharides,...
|
|
|
7517891 |
Camptothecin derivatives and improved synthetic methods
The present invention relates to compositions and methods for preparing pharmaceutical compositions. In some embodiments, the invention includes compounds and methods of resolving chiral compounds....
|
|
|
7514412 |
Anticancer biangeloyl saponins
Novel compounds such as compounds designated herein as Y or Y3, Y1, Y2, Y8, Y9 and Y10 are disclosed. These compounds have anticancer activity. The compounds of the present invention are obtainable...
|
|
|
7423133 |
Fluorescent glycosides and methods for their use
Fluorescent glycosides containing aromatic hydrocarbon groups are useful in labelling and detection methods for a wide array of chemical and biological molecules. Assembly of multiple analogs to...
|
|
|
7375087 |
Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof
The present invention provides pyrazole derivatives represented by the general formula:
wherein R 1 represents H, an optionally substituted C 1-6 alkyl group etc.; one of Q and T represents a...
|
|
|
7375090 |
Glucopyranosyloxy-pyrazoles, pharmaceutical compositions containing these compounds, the use thereof and processed for the preparation thereof
The present invention relates to glucopyranosyloxy-pyrazoles of general formula
wherein
R 1 to R 6 and R 7a , R 7b , R 7c are defined as in claim 1 , the tautomers, the stereoisomers, the...
|
|
|
7371730 |
Crystals of glucopyranosyloxybenzyl benzene derivative
The present invention provides crystals of 2-(4-methoxybenzyl)phenyl 6-O-ethoxycarbonyl-β-D-glucopyranoside, pharmaceutical compositions containing the same and their uses, which exhibit excellent...
|
|
|
7371733 |
Anti bacterial compounds
The invention relates to novel paranmycin compounds that have activity against gram positive and gram negative bacteria, preferably bacteria that are resistant to other antibiotics. Paranmycins are...
|
|
|
7312200 |
9-ketospinosyn derivatives
The present invention relates to derivatives of 9-keto spinosyns, which are substituted by a ═N—(O, NH or NR x )—R y moiety in the C-9 position, to methods for their manufacture, and to...
|
|
|
7294618 |
Glucopyranosyloxypyrazole derivatives and medicinal use thereof
The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula:
wherein R 1 , R 2 and R 3 represent a hydrogen atom or a halogen atom; R 4 represents...
|
|
|
7271153 |
Nitrogenous heterocyclic derivatives, medicinal compositions containing the same, medicinal uses thereof, and intermediates therefor
The present invention provides nitrogen-containing heterocyclic derivatives represented by the general formula:
wherein X 1 and X 3 independently represent N or CH; X 2 represents N or CR 2...
|
|
|
7217697 |
Glucopyranosyloxypyrazole derivative medicinal composition containing the same medicinal use thereof and intermediate therefor
The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula:
wherein R 1 is a hydrogen atom or a hydroxyalkyl group; one of Q and T is a group...
|
|
|
7189702 |
Glucopyranosyloxypyrazole derivatives and medicinal use thereof
The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula:
wherein one of Q and T represents a group represented by the general formula:
while...
|
|
|
7160867 |
Rapamycin carbohydrate derivatives
This invention provides modified rapamycins that have specific monosaccharide(s), oligosaccharide(s), pseudosugar(s) or derivatives thereof attached through a linker to create rapamycin...
|
|
|
7132403 |
Antihelminthic anthraquinones and method of use thereof
Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the...
|
|
|
7105491 |
Biosynthesis of enediyne compounds by manipulation of C-1027 gene pathway
This invention provides nucleic acid sequences and characterization of the gene cluster responsible for the biosynthesis of the enediyne C-1027 (produced by Streptomyces globisporus ). Methods are...
|
|
|
7101856 |
Thiophene glycoside derivatives, processes for the preparation, medicaments comprising these compounds, and the use thereof
Novel thiophene glycoside derivatives of the formula I:
in which the radicals have the stated meanings, and the physiologically tolerated salts thereof and processes for their preparation are...
|
|
|
7087579 |
Glucopyranosyloxypyrazole derivatives and medicinal use thereof
The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula:
wherein one of Q and T represents a group represented by the general formula:
while...
|
|
|
7084123 |
Glucopyranosyloxypyrazole derivatives and use thereof in medicines
The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula:
wherein R represents a hydrogen atom, a lower alkyl group or a group forming a prodrug:...
|
|
|
7078386 |
Enhancing agent for nerve growth factor production comprising a compound having a coumarin backbone or a compound having a 2-dimethyl chroman backbone
The present invention relates to a medicament, a food, a beverage or a feed, each comprising as an effective ingredient a compound having an enhancing action for NGF production, which is effective...
|
|
|
7060686 |
Anti-inflammatory compounds derived from Pseudopterogorgia elisabethae
Methods for treating, preventing, or inhibiting diseases and disorders associated with inflammation, cell-proliferation, and pain comprising the administration of a compound having the structural...
|
|
|
7053060 |
Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof
The present invention relates to glucopyranosyloxybenzylbenzene derivatives represented by the general formula:
wherein R 1 represents a hydrogen atom, a hydroxy group, a substituted or...
|
|
|
7052863 |
Alizarin-based chromogenic substrates, their uses and composition containing same
An alizarin-based chromogenic substrate, a composition containing the substrate, and its use to detect the presence of an enzymatic activity are disclosed. The substrate is particularly applicable...
|
|
|
7049301 |
Quercetin derivatives and their medical usages
This invention relates to quercetin derivative, its preparation, and a pharmaceutical combination, as well as their medical uses for the prevention or treatment of diseases related to 5HT 1A ...
|
|
|
7034130 |
Method for producing novel spinosyn derivatives
The present invention relates to methods for producing novel spinosyn derivatives which are substituted with a 1-hydroxy-ethyl radical in the C-21 position and to novel spinosyn derivatives of this...
|
|
|
6927209 |
5-thio-β-D-xylopryanoside derivatives, preparation, method, pharmaceutical compositions containing them and their therapeutic use
The present invention relates to novel compounds of formula (I):
in which:
R 1 , R 2 and R 3 , which are identical or different, are each independently:
a (C 1 -C 6 )alkyl group, a...
|
|
|
6887854 |
Compounds as dynamic organ function monitoring agents
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function...
|
|
|
RE38723 |
Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells
The subject invention provides substrates useful for analyzing the metabolic activity in cells by improving the retention of a detectable reporter molecule only in intact cells where a particular...
|
|
|
6875746 |
Anticancer anthraquinones and method of use thereof
Anthraquinones are described which have anticancer or antitumor activity and which are useful for inhibiting cancer cells and cells comprising tumors in vitro or in vivo. Preferably, the...
|
|
|
6872706 |
Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same
The present invention relates to glucopyranosyloxybenzylbenzene derivatives represented by the general formula:
wherein P represents a group forming a prodrug; and R represents a lower alkyl...
|
|
|
6867230 |
Hygromycin A derivatives
This invention relates to compounds of the formula
and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R 1 , R 2 , R 3 and R 10 are as defined herein. The...
|
|
|
6844346 |
Chromogenic substrates of sialidase and methods of making and using the same
The subject invention discloses materials and methods for the design, synthesis, and biochemical evaluation of chromogenic substrate compounds for sialidases of bacterial, viral, protozoa, and...
|
|
|
6818657 |
Bioprecursors of a retinoic derivative and pharmaceutical and/or cosmetic compositions
The present invention relates to a ternary glucosyl complex which is a bioprecursor of at least one retinoic active ingredient for percutaneous application, having formula (I), wherein E represents...
|
|
|
6800742 |
Method for producing β-D-ribofuranose derivatives or optical isomers thereof
The present invention provides a method for efficiently producing β-D-ribofuranose derivatives or optical isomers thereof, useful as synthetic intermediates of pharmaceutical nucleic acid-series...
|
|
|
6794497 |
Aminofuranose compounds
The present invention provides compounds and methods of synthesizing furanose and aminofuranose compounds of Formula I which are useful fro treating rheumatoid arthritis, immunomodulatory...
|
|
|
6784159 |
Triterpene saponins from soybeans for treating kidney disease
A method of treating polycystic kidney disease is described. The method involves administering soyasaponin B b to an animal in need thereof.
|
|
|
6737518 |
Process for preparation of 4,5-epoxymorphinan-6-oxyglucuronides
Conjugation of 4,5-Epoxymorphinan-6-ols with Bromoglucuronides in the presence of Zinc containing compounds as activator under conditions capable of forming 4,5-Epoxymorphinan-6-oxyglucuronides is...
|
|
|
6713454 |
Prodrugs of etoposide and etoposide analogs
The present invention provides amphiphilic prodrugs comprising a therapeutic compound conjugated to an PEG-oligomer/polymer and methods for using said prodrugs to enable oral drug delivery and/or...
|
|
|
6693179 |
Morphine-6-glucuronide synthesis
The invention provides a novel method for synthesizing Morphine-6-Glucuronide comprising the step of reacting 3-O-pivaloyloxymorphine and methyl 1α,2-ethylorthopivalate-3,4-di-O-pivaloylglucouronate.
|
|
|
6693085 |
Macrolide compound JK
Compound JK represented by the general formula (1): wherein R is H or —CH 3 ; or a pharmaceutically acceptable salt thereof. Compound JK has an excellent antimicrobial activity even against...
|
|
|
6670193 |
Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same
The present invention provides fluorescent nucleoside analogs which comprise a fluorescent cyclic compound joined to a carbon of a sugar molecule such as pentose, hexose, ribose or deoxyribose or...
|
|
|
6642375 |
Fluorescent substances
The present invention provides a fluorescent substance which is represented by a formula: A-B-C wherein A is a residue of natural or synthetic nucleotide, oligonucleotide, polynucleotide, or...
|
|
|
6642366 |
Process for making morphine-6-glucuronide and its analogues using haloglucuronate ester intermediates
A process for manufacturing morphine-6-glucuronide and related compounds of the general structure of Formula 1: wherein optionally substituted morphine is conjugated with an optionally...
|
|
|
6624317 |
Taxoid conjugates as antimitotic and antitumor agents
Compounds according to formula I: T 1 —L—T 2 (I), wherein T 1 is a taxoid group, preferably of Formula II: wherein R 1 is C 6 H 5 ; R 2 is O; L is a linking group; and T 2 is a...
|
|
|
6602899 |
β-D-5 thioxylose derivatives, preparation method and therapeutic use
|