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5808020 |
Optical reaction cell and light source for 18F! fluoride radiotracer synthesis
Apparatus for performing organic synthetic reactions, particularly no-carrier-added nucleophilic radiofluorination reactions for PET radiotracer production. The apparatus includes an optical...
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5808049 |
Stereospecific 5-fu esters and methods for preparing same
There is disclosed an ester compound that is resistant to decomposition in blood, but is quickly hydrolyzed in cancer cells, and functions as an anticancer agent. The ester compound has a structure...
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5808053 |
Modificaton of starch
The invention generally relates to a process for modification of cationic starch at which the cationic starch is treated, in the presence of water, with an aluminium compound. The modified cationic...
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5808040 |
L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides
A method for stabilizing an oligonucleotide by including a β-L-2'-deoxy-2'-fluoro-arabinofuranosyl nucleoside at the 5'-terminus, the 3'-terminus, or in the interior of the oligonucleotide. The...
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5808018 |
Fluorine containing sialyl Lewis X derivatives and synthetic intermediates thereof
A sialyl Lewis X derivative represented by the general formula: ##STR1## in which a hydroxyl group at the 2 position of fucose is replaced with a fluorine atom, and a synthetic intermediate...
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5808047 |
Process for the preparation of 2,2'-anhydro- and 2'-keto-1-(3',5'-di-O-protected-β-D-arabinofuranosyl) nucleosides
A process for the preparation of compounds of the formula: ##STR1## wherein Pg and R are protecting groups and B is a nucleobase. The process uses protected nucleobases to form 2,2'-anhydro...
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5804403 |
Stable aqueous reagent containing NAD
A stable aqueous NAD reagent useful in the measurement of analytes in biological fluids, particularly ethanol and lactate. For the determination of alcohol, the reagent contains alcohol...
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5801239 |
Process for the preparation of alkali salt of carboxy alkyl cellulose
This invention relates to a process for the preparation of alkali salt of carboxyalkyl cellulose with good solubility in salt water which is useful for pertroleum drilling muds, which comprises (a)...
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5801240 |
Method for extracting semi-refined carrageenan from seaweed
An improved method of producing semi-refined kappa carrageenan is provided having processing steps including: (a) pre-rinsing carrageenan containing seaweed; (b) cooking the seaweed in a cooking...
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5795869 |
Sulfated lyso-ganglioside derivatives
Semisynthetic analogues of gangliosides selected from the group consisting of N-sulfo-, N-hydrocarbyl-sulfonyl- and N-hydrocarbyloxy-sulfonyl-N,N'-dilyso-gangliosides and the N'-acyl derivatives...
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5795749 |
Use of 2-deoxyribose-5-phosphate aldolase to prepare 2-deoxyfucose, analogues and derivatives
Processes using 2-deoxyribose-5-phosphate aldolase (DERA) are described for the preparation of 2-deoxyfucose and related compounds. In one embodiment, DERA is used to catalyze the condensation of...
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5795979 |
Water-insoluble glucan purification method
The present invention relates to a water-insoluble glucan purification method characterized in that a culture solution of a microbe that produces water-insoluble glucan or a microbial...
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5792858 |
Lysosphingolipid derivatives
Novel derivatives of lysophingolipids free from sialic acids which are N-acyllysosphingolipids having one of the two formulae: ##STR1## in which -A- stands for the group --CHCH-- or --CH 2 --CH...
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5792839 |
Catalytic method of forming a glycosidic linkage
The invention relates to methods that permit the rapid construction of oligosaccharides and other glycoconjugates. Methods for forming multiple glycosidic linkages in solution in a single step are...
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5792843 |
Process for the production of alkyl and/or alkenyl oligoglucosides
Alkyl and/or alkenyl oligoglucosides can be produced at high reaction rates by a process in which glucose having a particle size distribution of at least 80% in the 20 to 300 μm range is subjected...
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5792857 |
Substituted derivatives of per (3,6-anhydro) cyclodextrins, their preparation process and their use for separating ions
The invention relates to substituted derivatives of per(3,6-anhydro)cyclodextrins, their preparation process and their use for the separation of ions. These derivatives comply with one of the...
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5789571 |
Method of making free acids from polysaccharide salts
A free acid form of a polysaccharide is produced from its alkali-metal salt. In one example, free-form hyaluronic acid is produced by preparing a solution of an alkali-metal salt of hyaluronic...
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5789580 |
Selectively fluorinated organic compounds
A process for the preparation of a selectively fluorinated organic compound, which process includes reaction of a precursor of said organic compound, the precursor containing at least one Group VI...
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5789579 |
Acidic polysaccharide
The invention provides an acidic polysaccharide by culturing acidic polysaccharide-producing germ belonging to Aureobasidium sp. isolated from soil, which has no toxicity and is applicable to...
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5789572 |
Method for the preparation of 1,4,-anhydro-2-deoxy-d-erythropentitol
Proposed is a novel synthetic route for the preparation of 1,4-anhydro-2-deoxy-D-erythropentitol, which is a useful material in the synthesis of antibiotics, starting from 2-deoxy-D-ribose via...
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5789392 |
Saccharide composition with reduced reducibility, and preparation and uses thereof
A saccharide composition with a reduced reducibility which is prepared by hydrogenating a saccharide mixture comprising reducing saccharides and non-reducing saccharides consisting of trehalose...
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5789581 |
Process for obtaining malonyl isoflavone glycosides and obtaining isoflavone glycosides or isoflavone aglycons from malonyl isoflavone glycosides
A malonylisoflavone glycoside present in soybean is obtained efficiently. In addition, the corresponding isoflavone glycoside and aglycone are obtained from the malonylisoflavone glycoside. An...
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5786469 |
1-C-perflouroalkyl glycosides, preparation process and uses thereof
The invention relates to 1-C-perfluoroalkyl glucosides consisting essentially of a monosaccharide having an anomeric carbon directly linked to a perfluoroalkyl radical and a hydroxyl group. These...
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5783677 |
Deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds
The present invention relates to a method for making a compound of the structure: ##STR1## comprising the steps: (a) adding 6-deoxy-α-L-mannopyranosyl bromide, 2,3,4-tri-O-benzoate; DMSO; a base,...
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5783569 |
Uses for underivatized, aqueous soluble β(1-3) glucan and compositions comprising same
The present invention relates to neutral, aqueous soluble β-glucans which exert potent and specific immunological effects without stimulating the production of certain cytokines, to preparations...
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5782982 |
Method of removing silica or silicates from solids resulting from the strong acid hydrolysis of cellulosic and hemicellulosic materials
A method of removing silica or silicates from solids results from the acid hydrolysis of materials containing cellulose and hemicellulose is disclosed. The method includes the steps of treating the...
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5783693 |
Methods for synthesizing sulfated disaccharide inhibitors of selectins
Sulfated disaccharides characterized by the ability to inhibit the binding of selectin to its physiologically-relevant ligand are disclosed. Included are efficient and inexpensive methods for...
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5780620 |
Non-reducing oligosaccharides and their production and use
Novel non-reducing oligosaccharide having a structure represented by the formula of alpha-D-oligoglucosyl alpha-D-oligoglucoside is obtained by exposing either an aqueous solution which contains...
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5780618 |
Oxidized cellulose
A method for making an oxidized cellulose product from a cellulose material is disclosed. The method involves oxidizing a cellulose material into an oxidized cellulose product, comprising treating...
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5780619 |
Starch graft poly(meth)acrylate blast media
The invention discloses a starch graft poly(meth)acrylate blast media which is effective in paint removal. The media is superior to a physical blend of the components (i.e., starch and acrylic...
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5777091 |
Phosphonomethylated chitosans
Phosophonomethylated chitosans containing repeating units of formula ##STR1## wherein R 1 is hydrogen or a radical of formula ##STR2## R 2 is a radical of formula (1a), X 1 and X 2 are each...
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5777101 |
Acetylation of lignocellulosic materials
The invention relates to a process for the acetylation of lignocellulosic materials (LM) by (a) bringing the LM into intimate contact with an acetylating agent comprising acetic anhydride as the...
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5777102 |
Carrageenan-containing product and a method of producing same
A method of producing a carrageenan-containing product comprising reacting a carrageenan-containing seaweed starting material in a substantially homogenous mixture of a solvent in which carrageenan...
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5773607 |
Processes for preparing 2'-deoxy-2'-fluorocoformycin and stereoisomers thereof
2'-Deoxy-2'-fluorocoformycin and 2'-deoxy-8-epi-2'-fluorocoformycin are synthesized in this invention through a multi-stage process via 3,5-di-O-benzoyl-2-deoxy-2-fluoro-α- and -β-D-ribofuranosyl...
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5773608 |
Process for preparing stabilized chitin derivative compounds
A process for sterilizing a polysaccharide composition containing chitosan, a chitosan derivative or a chitin derivative without substantially degrading the polysaccharide. The process has the...
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5773605 |
Sulfated glycosaminoglycanoid derivatives of the heparin sulfate type
The invention relates to sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type, of which N-sulfate, N-acetate, and hydroxy groups, are replaced by alkoxy, aryloxy,...
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5773596 |
Preparation of ganglioside having ceramide moiety labeled with fluorescence
A ganglioside derivative in which a ceramide moiety is labeled with a fluorescent dye represented by the formula (I): ##STR1## wherein --O--R--O-- is a saccharide chain constituting the...
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5773606 |
Catalyst regeneration
The present invention relates to the regeneration of a supported molybdenum catalyst which has been used for the epimerisation of a saccharide. The preferred epimerisation is the conversion of...
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5773604 |
Polyol composition, process for its preparation and its applications
The invention relates to a polyol composition exhibiting a very high heat stability and a very high chemical stability, characterized in that it exhibits an optical density lower than or equal to...
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5773256 |
Methods for the production of esters of α-glucosides and uses thereof
Disclosed is a process of enzymatically preparing α-glucoside esters. First, α-glucosides are produced by placing an acyclic alcohol or a mixture of acyclic alcohols having a water solubility of...
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5773595 |
Cationic sugar surfactants
A cationic sugar surfactant made by a process involving: (a) reacting an alkyl or alkenyl oligoglycoside of the formula (I): R 1 O-- G! p (I) wherein R 1 ...
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5770712 |
Crosslinked hydrogel beads from chitosan
A chitosan support material is made with crosslinking and installation of a spacer arm between the chitosan matrix and an epoxy terminal group at the distal end of the spacer arm. Among other...
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5770710 |
Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methlytrithio group
A process is described for producing substituted disulfide analogs of the family of antibacterial and antitumor agents known collectively as the LL-E33288 complex.
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5767269 |
Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics
The present invention generally relates to a processes for preparing low affinity, low molecular weight heparins (LA-LWM-heparins) which are endowed with pharmacological and therapeutic properties...
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5767255 |
Glucose- and sophorose-lipids, a process for their preparation and their use
The present invention relates to glucose- and sophorose-lipids of the formula I ##STR1## in which R 4 is --OH or a group of the formula II, ##STR2## n is an integer from 2 to 26, R 1 and R 2 ...
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5767257 |
Methods for producing polyol fatty acid polyesters using atmospheric or superatmospheric pressure
Methods for the solventless transesterification of a polyol comprise reacting polyol with fatty acid alkyl ester in the presence of a basic catalyst to produce polyol fatty acid polyester product...
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5763157 |
Biological reagent spheres
A reagent sphere is disclosed comprising at least one biological reagent and a glass-forming filler material in a concentration sufficient to facilitate formation of a glassy, porous composition,...
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5762943 |
Methods of treating type I hypersensitivity using monophosphoryl lipid A
Methods and compositions for treating type I immunoglobin E (IgE)-dependent hypersensitivity by the administration of monophosphoryl lipid A (MLA) or 3-deacylated monophosphoryl lipid A (3D-MLA)...
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5763413 |
Lewis-associated compound, process for producing the same, and anti-inflammatory
A Lewis-associated compound, represented by general formula (I), a process for producing the same, and an anti-inflammatory, wherein R 1 and R 3 represent each hydrogen, m SO 3 H or CH 2 COOH;...
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5763427 |
Compositions and methods for inhibiting thrombogenesis
The present invention provides compositions and methods for inactivating thrombin bound to fibrin within a thrombus or clot, whereby the ability of clot-bound thrombin to catalytically promote...
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