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5977350 |
Process for the oxidation of di-, tri-, oligo- and polysaccharides into polyhydroxycarboxylic acids
A process is provided for preparing polyhydroxycarboxylic acids by the selective oxidation of di-, tri-, oligo- and polysaccharides in an alkaline medium using an oxygenous gas in the presence of...
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5972905 |
Use of oligosaccharides for the treatment of pruritus cutaneus associated with renal failure
A pharmaceutical agent for improvement in pruritus cutaneus associated with renal failure and/or for the treatment of renal failure and/or its complications containing as an effective ingredient...
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5972349 |
Synthesis of polyribosylribitol phosphate oligosaccharides
Polyribosylribitol phosphate oligosaccharides are produced in a multistep process. The compound of the formula: ##STR1## wherein R 1 is a first protecting group and R 2 is a second protecting...
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5972907 |
Synthetic core 2-like branched structures containing GalNAc-lewis.sup.x and Neu5Acα2-3Galβ1-3GalNAc sequences as novel ligands for selectins
Compounds which bind to selectin receptors and thus may modulate the course of inflammation, cancer and related processes by intervening with cell-cell adhesion events. Further, such compounds can...
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5959101 |
Production of polysaccharide-based polycarboxylates
A continuous process for the production of polycarboxylic acids or salts thereof from polysaccharides involving contacting a polysaccharide with an oxidizing agent selected from the group...
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5959089 |
Amino-cyclodextrin syntheses
There are disclosed certain amino or azido cyclodextrin ethers, which have similar or improved properties to known cyclodextrins. The novel compounds are substituted cyclodextrins having...
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5958899 |
Polysaccharides having a high iduronic acid content
Process for the preparation of polysaccharides having a high iduronic acid content comprising: a) N-deacetylation of the polysaccharide K5 from E. coli or of the heparan sulfate or O-desulfation...
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5955079 |
Dual carrier immunogenic construct
A dual carrier immunogenic construct comprised of at least one primary carrier comprising large molecular weight molecule of greater than a 70 KD molecular weight and at least one secondary carrier...
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5955326 |
Production of microbial cellulose using a rotating disk film bioreactor
A new microbial cellulose with high water content and process for making the new microbial cellulose utilizes a trough containing a biological medium and a cellose producing micro organism. A...
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5955324 |
Process for producing carbohydrate or glycoconjugate
To provide a process for producing a carbohydrate or a glycoconjugate without forming any hydrolytic product of the remodeled sugar chain. A process for producing a carbohydrate or a glycoconjugate...
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5952204 |
β-fructofuranosidase, its preparation and uses
A β-fructofuranosidase with a molecular weight of 49,000±5,000 daltons on SDS-PAGE, an isoelectric point of 4.6±0.5, an optimum pH of about 5.5-6.0, and an optimum temperature of about 50° C....
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5951987 |
Polysaccharide vaccine to enhance immunity against brucellosis
A vaccine comprising purified outer-polysaccharide (OPS) is effective for protection against brucellosis. The vaccine is derived from Brucella or a variety of cross reactive bacteria. The vaccine...
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5948904 |
Process for the preparation of aromatic carbamoyl-substituted polysaccharide derivatives
The invention relates to a process for the preparation of polysaccharide-N-arylcarbamates in suitable form as supports for chromatography, which process comprises adding to polysaccharide...
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5939466 |
Poly-unsaturated carbohydrate derivatives, polymers thereof and their use
The present invention relates to polymerizable derivatives of carbohydrates comprising a carbohydrate radical and more than one radically polymerizable hydrocarbon group which is linked optionally...
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5939404 |
Cancer metastasis inhibitor containing a streptococcus agalactiae Ia type or Ib type surface polysaccharide as a main ingredient
The present invention relates to the technology for inhibiting the cancer metastasis, and is aimed at the provision of a pharmaceutical composition for effectively inhibiting the metastasis of the...
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5935636 |
Trehalose and its production and use
Microorganisms which are able to produce maltose/trehalose conversion enzyme, a novel enzyme, are cultivated in nutrient culture media with malose. During the cultivation, the microorganisms...
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5932639 |
Maltodextrin-based adhesives
The present invention is directed to remoistenable and non-remoistenable adhesives which contain at least about 50 wt % of a maltodextrin syrup having a reducing sugar content of about 5-19...
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5929047 |
Anti-viral agent prepared by basic and acidic extraction of mangraves
An anti-viral agent comprising as the effective component, an alkali extract of mangroves, Momordica charantia, and Aspalathus linearis belonging to Leguminosae family. The effective component is...
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5925747 |
Pumpable water-containing surfactant concentrates
Pumpable water-containing surfactant concentrates with a solids content of 30 to 60% by weight containing (a) alkyl and/or alkenyl oligoglycosides and (b) amphoteric or zwitterionic surfactants in...
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5922691 |
Crystalline maltotetraosyl glucoside, and its production and use
Novel crystalline maltotetraosyl glucoside is obtained by crystallizing maltotetraosyl glucoside from a solution of maltotetraosyl glucoside, prepared by either exposing an aqueous solution of...
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5919697 |
Color clarification methods
The invention is directed to agents used in the retention of color values on fabrics formed from cellulose fibers (color clarification agents) and to a method for treatment of such fabrics. The...
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5919668 |
Non-reducing saccharide and its production and use
In the production of non-reducing saccharides such as trehalose, alpha-glycosyl trehaloses and alpha-glycosyl alpha-glycosides where a solution of liquefied starch is subjected either to...
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5916881 |
High trehalose content syrup
A non- or substantially non-crystalline high trehalose content syrup, which dissolves trehalose in an amount over the water solubility and dissolves other oligosaccharide having a trehalose...
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5912330 |
Crystalline maltosyl glucoside, and its production and use
Novel crystalline maltosyl glucoside is obtained by crystallizing maltosyl glucoside from a maltosyl glucoside solution, prepared by exposing either an aqueous solution containing trehalose and an...
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5910579 |
Processes for the preparation of αGal(1->4)βGal (1->4) Glc-OR
Disclosed are novel synthetic processes for the preparation of the trisaccharide αGal(1➝4)βGal(1➝4)Glc-OR compounds.
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5910490 |
Use of oligosaccharides in the prevention and treatment of the aging of tissues
Composition for the treatment or prevention of the symptoms of connective tissue ageing, characterized in that it contains one or more oligosaccharides with 2 to 5 oligosaccharide residues or a...
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5908767 |
Non-reducing saccharide and its production and use
Non-reducing saccharides including alpha-glycosyl trehaloses, alpha-glycosyl alpha-glycosides and trehalose are easily produced by cultivating microorganisms capable of producing non-reducing...
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5908928 |
Alkyl polyglycoside ether carboxylates
A novel surfactant of formula I: R 1 O(R 2 O) b (Z) a OCH 2 COO - X +I wherein R 1 is a monovalent organic radical having from about 6 to about 30 carbon atoms; R 2 is divalent alkylene...
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5902796 |
Bioactive factors of aloe vera plants
A bioactive Factor produced, separated and isolated from either an aloe vera leaf or a product derived and processed from an aloe leaf, such as raw aloe vera gel, freeze-dried aloe vera gel...
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5900478 |
Activated mono-, di-, and polysaccharides reaction products thereof, their preparation and uses
Reaction at the interface of an organic solution containing an acidic reactant and an aqueous alkaline solution containing nonreducing carbohydrates such as sucrose, sugar alcohols, cyclodextrins,...
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5900481 |
Bead linkers for immobilizing nucleic acids to solid supports
Novel compositions comprised of at least one bead conjugated to a solid support and further conjugated to at least one nucleic acid and preferred methods for making the novel compositions are...
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5897987 |
Use of arabinogalactan in cell cryopreservation media
Methods and compositions for cryopreserving somatic cells are provided. In one embodiment, a cell cryopreservation medium is provided which includes an effective amount of arabinogalactan to...
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5891450 |
Polysaccharide derivative, and preparation process and use thereof
Disclosed herein are a polysaccharide derivative obtainable by substituting a part or the whole of hydrogen atoms of hydroxyl groups in a polysaccharide or a derivative thereof by the following...
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5888987 |
Solvent dried polysaccharide sponges
The invention provides a method of preparing water-insoluble polysaccharide sponges, and sponges obtained by means of the method. The method comprises: (a) providing an aqueous solution of a...
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5889180 |
Use of small pore silicas as a support for a chiral stationary phase
Small pore silicas serving as the inert core support in chiral stationary phases show a surprising increase in column capacity relative to conventional chiral stationary phases having large pore...
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5889179 |
Bacteria and enzymes for production of alternant fragments
A new enzyme, alternanase, which is effective for the endo-hydrolytic cleavage of alternan, producing a thinned composition of low molecular weight fractions which exhibit reduced viscosity and...
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5888815 |
Cell cultivation method and medium
The invention relates to a method of cultivating mammalian cells expressing recombinant Factor VIII in a serum-free cell culture medium of the type that normally requires the presence of human...
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5888986 |
Method for treating the urinary bladder and associated structures using hyaluronic acid
A method of treating interstitial cystitis comprising contacting the transitional epithelium lining the urinary bladder and associated structures in a mammal having interstitial cystitis with a...
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5886168 |
Low D.E. starch conversion products having a sharp differentiation in molecular size
Starch containing amylopectin is hydrolyzed with an alpha-amylase, preferably derived from Bacillus stearothermophilus, under conditions which cause a non-random cleavage of the starch molecules to...
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5883243 |
Non-reducing saccharides, their preparations and uses
α-Isomaltosyl α-isomaltoside represented by O-α-D-glucopyranosyl-(1➝6)-α-D-glucopyranosyl O-α-D-glucopyranosyl-(1➝6)-α-D-glucopyranoside is a novel non-reducing saccharide which promotes...
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5880091 |
Glycoprotein ligand for P-selectin and methods of use thereof
P-selectin has been demonstrated to bind primarily to a single major glycoprotein ligand on neutrophils and HL-60 cells, when assessed by blotting assays and by affinity chromatography of 3 ...
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5877164 |
Plant rhamnogalacturonan II complexation of heavy metal cations
The present invention provides rhamnogalacturonan-II (RG-II) and relates to its ability to complex specific multivalent heavy metal cations. In the presence of boric acid, RG-II monomers form...
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5874417 |
Functionalized derivatives of hyaluronic acid
A composition of matter comprising a hyaluronate functionalized with a hydrazide at glucuronic acid sites of said hyaluronate, wherein the hydrazide is chosen from a group consisting of:...
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5869645 |
Method for isolating high molecular weight antineoplastic glycans using urea
A method for preparing a highly potent glycan extract from Mycobacteria by admixing at least one Mycobacterium with an aqueous solution of concentrated urea.
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5863908 |
Carboxymethylmannoglucans and derivatives thereof
A carboxymethylmannoglucan comprising tetrasaccharide units represented by the following general formula (I) and salt thereof. Further, the invention discloses a carboxymethylmannoglucan derivative...
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5863771 |
Saccharide composition comprising maltooligosylturanose and maltooligosylpalatinose, its preparation and uses
A saccharide composition comprising maltooligosyl derivatives of turanose and palatinose which can be readily produced, separated, and purified in a relatively-high yield from maltooligosylsucrose...
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5861505 |
Synthetic analog of sialic Lewis antigen from bacterial capsular polysaccharide
An analog of sialic Lewis antigen prepared from native capsular polysaccharide of Klebsiella 63 bacteria.
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5858994 |
Carbohydrate conjugates as inhibitors of cell adhesion
The invention relates to novel conjugates of tetrasaccharides, preferably of sialyl-Lewis X (SLeX) and sialyl-Lewis A (SLeA), having improved activity as inhibitors of cell adhesion, a process for...
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5858992 |
Non-reducing saccharides, their preparation and use
α-Isomaltosyl α-isomaltoside represented by O-α-D-glucopyranosyl -(1➝6)-α-D-glucopyranosyl O-α-D-glucopyranosyl-(1➝6) -α-D-glucopyranoside is a novel non-reducing saccharide which...
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5854368 |
Adjuvant for pharmaceutical preparations
A polyester represented by the following general formula (I) and a copolymer which comprises two structural units represented by the following general formulae (I') and (II). ##STR1## and a coating...
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