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8183228 |
Anticoagulant antithrombotic dual inhibitors comprising a biotin label
The present invention relates compounds of the formula: oligosaccharide-spacer-(GpIIb/IIIa antagonist), wherein the oligosaccharide is a negatively charged oligosaccharide residue comprising four...
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8173798 |
Vaccine
The invention relates to a vaccine for the treatment of disease caused by Neisseria, the vaccine including one or more immunogenic components for Neisseria serogroups, as well as antibodies to the...
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8168767 |
Formulations and methods for solid chitosan-containing blends
Chitosan-containing blends and methods of dissolving and using chitosan are disclosed. A blend includes a solid acid or a solid agent that generates a proton in situ in the presence of water mixed...
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8168778 |
Highly-branched starch, its production and uses
An object of the present invention is to provide a novel starchy substance having a retrogradation-resistance, a process for producing the starchy substance efficiently from a material starch by...
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8163715 |
Inulin of very high chain length
The invention relates to a long-chain inulin and its preparation from artichoke roots, to its use in foodstuffs and cosmetic preparations and to foodstuffs and cosmetic preparations which comprise...
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8158608 |
Bioactive fraction from Zingier officinale and a process for the preparation thereof
Ulcer is a serious oxidative stress induced disease with complex pathologic events including upregulation of H+K+ ATPase of parietal cell (PC) membrane, damage of mucin layer around PC, PC-DNA...
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8143235 |
Use of dietary fibres against muscle wasting
A composition nutritional containing dietary fibres is useful for the treatment of muscle wasting, if the dietary fibre comprise at least 30 wt. % of galacto-oligosaccharides or other...
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8137681 |
Polyanionic polymer adjuvants for Haemophilus influenzae B saccharide vaccines
The present invention relates to the field of vaccines, and in particular vaccines comprising antigens of low isoelectric point at pH 7.0, in particular the capsular polysaccharide or...
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8137685 |
Hyaluronic acid compound, hydrogel thereof and joint treating material
A hyaluronic acid compound which is a reaction product between hyaluronic acid and a phosphatidyl ethanolamine. This compound has biocompatibility and bio-safety, and can be formed into a hydrogel...
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8129128 |
Immunoassay reagent compositions for diagnosing multiple sclerosis
This application is related to immunoassay reagent compositions comprising a glycan reagent for diagnosing multiple sclerosis.
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8124575 |
Polymeric surfactants based upon alkyl polyglycosides and sugars
The present invention relates to a series of polyglycoside derivatives that are (a) polymeric (that is cross linked with hydroxypropyl linkages) and (b) contain additional functional groups...
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8114466 |
Methods of applying coating to the inside surface of a stent
A method of applying a coating material to a stent includes the steps of providing a generally tubular stent having an inside surface and an outside surface and applying a coating material to the...
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8114856 |
Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.
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8110677 |
Microwave-assisted extraction of polysaccharide from Artemisia sphaerocephala
This invention relates to a method of extracting crude polysaccharide by microwave-assisted from Artemisia sphaerocephala seed de-oiling dregs. In particular, the invention comprising:...
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8110380 |
Starch-based biodegradable material composition
A starch-based biodegradable material composition includes: an enzyme-hydrolyzed starch; and a biodegradable polyester selected from at least one of an aliphatic polyester of polybutylene succinate...
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8106007 |
Conjugates of a polypeptide and a pentasaccharide
The present invention relates to conjugates of a polypeptide and an oligosaccharide, wherein the polypeptide is conjugated to at least one oligosaccharide-spacer residue, the oligosaccharide being...
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8097437 |
Highly pure polysialic acid and process for preparation thereof
The instant invention provides highly pure Polysialic acid and process for preparation thereof.
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8088626 |
Chiral selectors for separating enantiomers of a compound
The invention relates to the use of compounds as new chiral selectors for separating the optical or enantiomeric isomers of a compound, wherein the chiral selector comprises at least one compound...
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8084053 |
Dry mouldable drug formulation
Solid pharmaceutical compositions and methods of making and administering for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the...
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8076313 |
Composition containing fermentable polysaccharides
The present invention relates to a composition to a nutritional composition comprising 0.1 to 15 gram fermentable e partially hydrolysed gum having a degree of polymerization between 10 and 300 per...
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8071758 |
Method for production of limulus-positive glycolipid, the limulus-positive glycolipid, and composition containing the limulus-positive glycolipid
It has been found that a limulus-positive glycolipid is present in xanthan gum derived from Xanthomonas, which has been commercially available and eaten for many years, and this was purified, and...
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8071759 |
Water soluble cholesterol derivatives
Four novel water soluble cholesterol derivative compounds are disclosed. These compounds have various applications in studies of membrane proteins, including drug screening and studies of receptor...
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8071569 |
Oxidized heparin fractions and their use in inhibiting angiogenesis
The present invention relates to a heparin fraction comprising constituents having molecular weights of from about 2,000 to about 4,000 daltons, wherein from about 1% to about 100% of hydroxyl...
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8053543 |
Filler for optical isomer separation
A polymer compound derivative, obtained by modifying part of the hydroxy or amino groups of a polymer compound having the hydroxy or amino groups with molecules of a compound represented by the...
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8048997 |
Process for drying uronic acid oligosaccharides
The present invention relates to a process for spray drying uronic acid oligosaccharides and to a powder compositions thus obtained. Typically the powder composition comprises between 25 and 100...
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8049004 |
Processes for making ethersuccinylated hydroxyl polymers
Processes for making ethersuccinylated hydroxyl polymers are provided.
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8026221 |
Method, composition and kit for antigenic binding of norwalk-like viruses
A method for detecting a Norwalk-Like Virus (NLV) in a biological sample, comprising the steps of: obtaining a biological sample suspected of containing a NLV; contacting the biological sample with...
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8022049 |
Polysaccharide produced by microorganism belonging to genus Bifidobacterium
A polysaccharide comprising galactose, glucose, rhamnose, and pyruvic acid as constituents, wherein the galactose, glucose, and rhamnose are contained in a molar ratio of 4:2:1, and the pyruvic...
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8017133 |
Multicomponent vaccines
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or...
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8013132 |
Synthetic compounds useful as nodulation agents of leguminous plants and preparation processes thereof
The present invention relates to synthetic compounds that are active on plants, especially as legume nodulation factors, and also as plant growth stimulators, and to methods for preparing such...
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8008275 |
Fucose containing proteoglycan or acidic glycan and their pharmaceutical use
A class of proteoglycans containing fucosylated acidic glycans, e.g., as produced by marine sponges and sea urchin embryos, have been found to stimulate selective proliferation of mammalian natural...
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8007818 |
Polyanionic polymer adjuvants for haemophilus influenzae B saccharide vaccines
The present invention relates to the field of vaccines, and in particular vaccines comprising antigens of low isoelectric point at pH 7.0, in particular the capsular polysaccharide or...
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8008276 |
Use of zwitterionic polysaccharides for the specific modulation of immune processes
The invention relates to three-dimensional molecular structure determination of polymers, three-dimensional computer molecular modeling, rational drug design, and immunomodulatory polymers. In...
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8003112 |
Meningococcal and pneumococcal conjugate vaccine and method of using same
This disclosure relates to vaccine formulations comprising an immunogenic composition for inducing antibodies to both S. pneumoniae and N. meningitides in a subject. In a preferred aspect, the...
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7989601 |
Heterobifunctional pan-selectin inhibitors
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the...
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7964561 |
Protein formulations for use at elevated temperatures
Liquid formulations of bone morphogenetic proteins are provided for prolonged use at elevated temperatures. More specifically, the invention relates to liquid formulations comprising rhGDF-5,...
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7956046 |
Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them
Oligosaccharide mixtures comprising anti-Xa activities of from 190 IU/mg to 450 IU/mg and anti-IIa activities of less than 0.2 IU/mg; and having constituent oligosaccharides with an average...
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7956045 |
Compositions and methods for animal treatment
A method of improving the health and production of ruminant animals, the method including the step of orally administering to the animal an effective amount of an indigestible oligosaccharide...
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7956047 |
Use of chondroitin sulphate E (CS-E) for the treatment of diseases or conditions related to collagen fibril formation
The present invention comprises the use of chondroitin sulphate (CS-E) or an active fragment thereof for the treatment of diseases or conditions related to collagen fibril formation. Said compounds...
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7951530 |
Cyclic maltosylmaltose, cyclic maltosymaltose-forming enzyme, their preparation and uses
An object of the present invention is to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme...
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7943596 |
Medicinal composition for ophthal use containing acetylated hyaluronic acid
The present invention provides an ophthalmic pharmaceutical composition containing acetylated hyaluronic acid and a pharmacologically acceptable carrier. Preferably, the average molecular weight of...
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7935683 |
Polysaccharide-carbon nanotube complex
Disclosed is a complex which comprises a carbon nanotube and a modified polysaccharide having a backbone chain with the side thereof being introduced with monosaccharide or oligosaccharide...
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7932236 |
Glycolipids
Novel synthetic gangliosides and pharmaceutical compositions containing such synthetic gangliosides are described. Methods of making the novel synthetic ganglioside compounds and compositions as...
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7928079 |
Polysaccharide-derived nitric oxide-releasing carbon-bound diazeniumdiolates
The invention relates to compounds capable of releasing nitric oxide wherein the compounds comprise a saccharide and at least one nitric oxide-releasing diazeniumdiolate [N2O2] functional group,...
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7923018 |
Vaccine
The invention relates to a vaccine for the treatment of disease caused by Neisseria, the vaccine comprising one or more immunogenic components for Neisseria serogroups, as well as antibodies to the...
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7910117 |
Vaccine
The invention relates to a vaccine for the treatment of disease caused by Neisseria, the vaccine including one or more immunogenic components for Neisseria serogroups, as well as antibodies to the...
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7902172 |
Method of promoting bone growth with hyaluronic acid and growth factors
A bone growth-promoting composition is provided comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to persist at an intra-articular site...
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7902170 |
Influenza virus binding, sialylated oligosaccharide substance and use thereof
The present invention is directed to human influenza virus binding substance containing at least one oligosaccharide chain, which comprises a terminal NeuNAcα6 linked to: (a) a linear or branched ...
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7897563 |
Use of oligomers and polymers for drug solubilization, stabilization, and delivery
The invention relates to the use of oligomers and polymers capable of rendering insoluble drugs soluble, protecting unstable drugs, and facilitating the delivery of drugs to their site of action....
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7893039 |
Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.
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