|
Match
|
Document |
Document Title |
|
|
8101746 |
Granular sucralose, and method of making it
Granular sucralose-containing particles are produced by the methods of the invention, which involve coating sucralose from solution to form granules with this coated sucralose on an outer region...
|
|
|
7943764 |
Method for producing sulphated glycosaminoglycans from biological tissues
A method for isolating sulphated glycosaminoglycans washes a mechanically cleaned tissue, exposes tissue in a solution of 0.1M phosphate pH 5.8-6.0 buffer heated to a temperature of 65° C. for 30 ...
|
|
|
7884203 |
Method of sucralose synthesis yield
The invention discloses a method for improving the yield of sucralose, including reacting sucrose to produce sucrose-6-acetate in the existence of an azo reagent as a catalyst and acetic acid as an...
|
|
|
7879807 |
Tetrasubstituted glucopyranosylated benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
Tetrasubstituted glucopyranosylated benzene derivatives of general formula (I) as defined according to claim 1, including the tautomers, the stereoisomers thereof, the mixtures thereof and the...
|
|
|
7858587 |
Glucopyranosyl-substituted difluorobenzyl-benzene derivates, medicaments containing such compounds, their use and process for their manufacture
Glucopyranosyl-substituted difluorobenzyl-benzene derivatives of general formula (I) as defined according to claim 1, including the tautomers, the stereoisomers thereof, the mixtures thereof and...
|
|
|
7847092 |
Method for preparation of F-18 containing organofluoro compounds in alcohol solvents
The present invention relates to a method for preparation of organofluoro compounds containing radioactive isotope fluorine-18. More particularly, the present invention relates to a method for...
|
|
|
7838499 |
Benzylbenzene derivatives and methods of use
Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds,...
|
|
|
7829118 |
Modified hyaluronic acid polymer compositions and related methods
The present application provides compositions comprising hyaluronic acid having low levels of functional group modification, mixtures formed by controlled reaction of such lightly modified...
|
|
|
7750146 |
Granular sucralose
Granular sucralose-containing particles are produced by the methods of the invention, which involve coating sucralose from solution to form granules with this coated sucralose on an outer region...
|
|
|
7741121 |
System for purification and analysis of radiochemical products yielded by microfluidic synthesis devices
The present application is generally directed to microfluidic devices and methods for the achievement and assessment of chemical and radiochemical purity of (microfluidic) radio-synthesis products....
|
|
|
7732596 |
Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof
The present invention provides nitrogen-containing fused cyclic derivatives represented by the following general formula or pharmaceutically acceptable salts thereof, or prodrugs thereof, which...
|
|
|
7709463 |
Idraparinux (SanOrg34006) for treatment of venous events in patients with deep venous thrombosis
The invention relates to a dose of 2.5 mg of the pentasaccharide methyl O-(2,3,4-tri-O-methyl-6-O-sulfo-α-D-glucopyranosyl)-(1→4)
-O-(2,3-di-O-methyl-β-D-glucopyranosyl uronic aci...
|
|
|
7666845 |
Compounds having inhibitory activity against sodium-dependent glucose transporter
The invention is directed to compounds of the formula (I) described herein, a pharmaceutically acceptable salt thereof, or a prodrug thereof, and pharmaceutical compositions and methods of treatment.
|
|
|
7626016 |
Process for preparing sucrose-6-ester
This invention relates to a method for preparing a sucrose-6-ester. The method includes (i) reacting sucrose with a N,N-dimethylcarboxamide dimethyl acetal in an inert aprotic solvent to form a...
|
|
|
7589193 |
C-aryl glucoside SGLT2 inhibitors and method
A compound of the formula I A method is also provided for treating diabetes and related diseases employing the above compound alone or in combination with another therapeutic agent.
|
|
|
7572929 |
Dithiocarbonate containing macromers and polymers derived therefrom
Dithiocarbonate-containing macromer that contain biodegradable or water-soluble segments, and polymers derived from the reaction of these dithiocarbonate-containing macromers, are disclosed. The...
|
|
|
7417109 |
Polymers for delivering nitric oxide in vivo
Disclosed are novel polymers derivatized with at least one —NOx group per 1200 atomic mass unit of the polymer. X is one or two. In one embodiment, the polymer is an S-nitrosylated polymer and is p...
|
|
|
7378519 |
Adduct of topiramate and tramadol hydrochloride and uses thereof
Processes for isolation and purification of enantiomerically enriched compositions comprising tramadol and topiramate, and also for the subsequent isolation of 1S,2S-tramadol hydrochloride, are...
|
|
|
7345117 |
Sulphated hyaluronic acid and sulphated derivatives thereof covalently bound to polyurethanes, and the process for their preparation
The present invention relates to the synthesis of a haemocompatible polymer, consisting of a polyurethane bound covalently to sulphated hyaluronic acid. These sulfated derivatives have...
|
|
|
7345166 |
Water soluble biodegradable polymeric photocatalysts
Novel antenna polymers characterized by a polymeric background of a biodegradable water soluble polymer and chromophores chemically bonded to the polymeric background have been found to be useful...
|
|
|
7244830 |
Glycopolymers and free radical polymerization methods
A glycopolymer composition is provided comprising glycopolymer molecules having a polymer backbone; a first pendent unit comprising a linking group connected to said polymer backbone and a...
|
|
|
7189843 |
Production of carrageenan and carrageenan products
The methods of the present invention prepare carrageenan products from processed seaweed material having a solids content of less than 25% by weight solids, using shear stress treatment. The...
|
|
|
7115586 |
Non-inclusion cyclodextrin complexes
The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization...
|
|
|
7087571 |
Alkyl polyglycoside derived sulfosuccinates
The invention relates to a series of polyglycoside derivatives that contain water-soluble sulfosuccinate groups introduced into the molecule by reaction with the hydroxyl groups present in the...
|
|
|
7084132 |
Artemisinins with improved stability and bioavailability for therapeutic drug development and application
A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation ...
|
|
|
7074919 |
Use of amphoteric polysaccharide for treating textile fiber articles
The invention concerns the use, in a composition for treating textile fiber articles in aqueous or moist medium, of an amphoteric polysaccharide, whereof the native skeleton is a polysaccharide...
|
|
|
7060685 |
Compounds and methods for inhibiting selectin-mediated function
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the...
|
|
|
7030237 |
Method and equipment for continuous and selective inclusion separation
In a reaction system having at least two liquid-liquid interfaces between an organic phase of raw material containing a compound(s) to be separated and an aqueous phase of an aqueous solution of...
|
|
|
7022682 |
Method for the treatment of diabetes
The present invention provides for a method for treatment and prevention of Type II Diabetes Mellitus and its complications comprising the step of administering to a patient a...
|
|
|
7001893 |
Inclusion complex of Rifampicin, an anti-tubercular drug, with β-cyclodextrin or 2-hydroxypropyl β-cyclodextrin and a process thereof
The present invention relates to an inclusion complex of Rifampicin and cyclodextrin (CD) that can be used as an anti-tubercular drug. The present invention also relates to a process for...
|
|
|
6984732 |
High-intensity sweetener composition and delivery of same
A composition for sweetening ingestable solids or liquids. The composition is compressed and comprises less than about 7.5 weight-% sucralose and one or more diluents. The composition is compressed...
|
|
|
6951934 |
Method for preparing functionalized β-(1,3)-glucan derivatives
The present invention relates to a novel method of chemically preparing functionalized derivatives of β-(1,3)-glucans, enabling obtaining oligosaccharides which are free or which comprise specific ...
|
|
|
6943248 |
Crystalline form of sucralose, and method for producing it
A crystalline form of sucralose, and a method of making it. The method involves continuously crystallizing sucralose from an aqueous solution by a process providing continuous removal and...
|
|
|
6927209 |
5-thio-β-D-xylopryanoside derivatives, preparation, method, pharmaceutical compositions containing them and their therapeutic use
The present invention relates to novel compounds of formula (I): in which: R1, R2 and R3, which are identical or different, are each independently: a (C1-C6)alkyl group,a pyridinyl group ora group...
|
|
|
6891035 |
Process for bulk autoclaving
Process for bulk autoclaving of polysaccharides, wherein the process includes: a) dissolving the polysaccharides in an aqueous solution and mixing until a homogeneous solution is obtained; b)...
|
|
|
6844329 |
Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative
The present invention relates to novel synthetic polysaccharides with antithrombotic activity exhibiting at least one covalent bond with biotin or a biotin derivative and to a process employing...
|
|
|
6828334 |
Fenofibrate-cyclodextrin inclusion complexes and their pharmaceutical composition
The present invention relates to pharmaceutical compositions containing fenofibrate in the form of an inclusion complex with cyclodextrin, having high dissolution profile and in vivo enhanced...
|
|
|
6812223 |
Crystalline glucosamine sulfate metal salts and processes for preparing the same
The present invention relates to novel crystalline glucosamine sulphate metal salts for use in the treatment of acute and chronic forms of rheumatic and arthritic diseases and of all the...
|
|
|
6809198 |
Sucralose composition and process for its preparation
The present invention provides an improved form of sucralose and a process for making it.
|
|
|
6670338 |
Pentasaccharides processes for their preparation and pharmaceutical compositions containing them
Pentasaccharides in acidic form and their pharmaceutically acceptable salts, the anionic form thereof having the formula: wherein:R represents hydrogen or an —SO3−, (C1-C3)alkyl or (C2-C3)acyl gro...
|
|
|
6660722 |
Therapeutical treatments
Therapeutical method comprising administration to a patient of an effective amount of especially soluble laminarin for the treatment of tumors and more generally of cancers of the group comprising...
|
|
|
6656922 |
Oral delivery of macromolecules
Polysaccharides, which are widely used as an anticoagulation drugs, especially heparin, are clinically administered only by intravenous or subcutaneous injection because of their strong...
|
|
|
6642366 |
Process for making morphine-6-glucuronide and its analogues using haloglucuronate ester intermediates
A process for manufacturing morphine-6-glucuronide and related compounds of the general structure of Formula 1: wherein optionally substituted morphine is conjugated with an optionally substituted...
|
|
|
6638916 |
Use of sulfated oligosaccharides as inhibitors of cardiovascular disease
A method for the inhibition of vascular smooth muscle cell hyperplasia in a human or other warm-blooded animal patient in need of such treatment, comprises administration to the patient of an...
|
|
|
6627751 |
Hydrophobically modified anionic cellulose ethers
A hydrophobically modified anionic cellulose ether obtainable by a process comprising reacting an alkali metal cellulose with at least three alkylating reagents A, B, and C. Reagent A is selected...
|
|
|
6627744 |
Synthesis of glycodendrimer reagents
The present invention relates to a chemically modified mutant protein including a cysteine residue substituted for a residue other than cysteine n a precursor protein, the substituted cysteine...
|
|
|
6589943 |
Formulation of amphiphilic heparin derivatives for enhancing mucosal absorption
Formulations for enhanced mucosal absorption of heparin are disclosed. In one embodiment, a powdered heparin composition is made by dissolving an amphiphilic heparin derivative including heparin...
|
|
|
6528497 |
Synthetic polysaccharides, their method of production and pharmaceutical compositions containing same
Novel synthetic polysaccharides for use in the treatment of pathologies associated with a coagulation dysfunction.
|
|
|
6495678 |
Immunosuppressant containing glucopyranose derivative as active ingredient
An immunosuppressant comprising Glucopyranose derivatives of the formula (I): wherein R is H, OH etc; G is —CH2CH(R1—R2)(R3—R4), in which R1 is a single bond, OCO-alkyl; R2, R4 is H, phenyl which...
|
|
|
6462191 |
Synthesis of 2-deoxy-2-fluoro-arabinose derivatives
A process for deoxofluorinating a C2-hydroxyl group of a furanose, includes: (a) mixing the furanose and a deoxofluorinating agent in a solvent to form a reaction mixture, and (b) heating the...
|