Matches 151 - 200 out of 320 < 1 2 3 4 5 6 7 >
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5008253 Sulfoamino derivatives of chondroitin sulfates of dermatan sulfate and of hyaluronic acid and their pharmacological properties  
Novel derivatives are disclosed as obtained from chondroitin sulfate, dermatan sulfate and hyaluronic acid, having a molar ratio between sulfate groups and carboxylic groups like that of heparin...
5003060 Readily dispersed/dissolved porous biopolymer granules  
Solid, free-flowing and nondusting porous biopolymer, e.g., xanthan gum, granules are produced in fluidized bed and are quickly dispersed/dissolved in aqueous media for use as thickening agents for...
4996305 Process for producing the antibiotic and antitumor agents LL-E33288.epsilon . ε-Br  
Processes for producing antibacterial and antitumor agents designated LL-E33288εI and LL-E33288ε-Br using triphenylphosphine or a sulfhydryl-containing reagent are disclosed. Processes for...
4986991 Chewing gum having an extended sweetness  
A chewing gum composition having an extended sweetness and flavor comprising a chewable gum base and a sweetener comprising 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose (TGS), also known as...
4987223 Derivatives of the uronic acid  
The invention relates to derivatives with a uronic acid structure having substituents selected among a reactive group, a functionalisable group and --OH functions blocked by protective groups....
4985550 Polyhydroxylated and highly fluorinated compounds, their preparation and their use as surfactants  
Compounds having a polyhydroxylated hydrophilic moiety, a highly fluorinated moiety and a functional junction group linking said moieties together, wherein said hydrophilic moiety is derived from a...
4983724 Inversion of 2,2-difluororibose to a 2,2-difluoroxylose and intermediates therefor  
A process and intermediates useful for the invrsion of 2-deoxy-2,2-difluororibose analogs to provide 2-deoxy-2,2-difluoroxylose analogs is described.
4980463 Sucrose-6-ester chlorination  
A process for the chlorination of sucrose-6-esters to produce 6',4,1'-trichlorosucrose-6-esters which comprises the steps of: (a) adding at least seven molar equivalents of an acid chloride to a...
4980462 Antiviral agents  
A second-step virus binding receptor is found in nature on the surface of animal and plant cells. This receptor is thought to be needed for virus penetration into target cells. The second-step...
RE33509 Brominated sucrose derivatives, compositions and methods of use  
Compounds of the general formula (I) are potent sweeteners, especially 4,1',6'-tribromo-4,1',6'-trideoxygalactosucrose: ##STR1## in which R' represents a chlorine or bromine atom; R 2 and R 3 ...
4978748 Intermediate and process for producing the antibacterial and antitumor agents LL-E33288ε-I and LL-E33288Epsilon-Br  
Processes for producing antibacterial and antitumor agents designated LL-E33288ε-I and LL-E33288ε-Br using triphenylphosphine at ice bath temperature are disclosed. Novel intermediates prepared...
4977143 Antibacterial and antitumor agents LL-E33288EPSILON-I and LL-E33288EPSILON-BR  
Antibacterial and antitumor agents designated LL-E333288ε-I and LL-E33288ε-Br and their production by strains of Micromonospora echinospora ssp. calichensis designated NRRL-15839, NRRL-15975 and...
4977254 Process for the chlorination of sugars  
Sugars and partly protected sugar derivatives are chlorinated by reaction of unprotected hydroxyl groups with thionyl chloride to form a persulphite followed by decomposition of the sulphite groups...
4977253 Process for the sulfation of alkyloligoglycosides  
An alkyloligoglycoside having an alkyl group content of 8 to 22 carbon atoms and having an average degree of oligomerization of 1 to 5 is sulfated with a sulfating agent in an organic solvent...
4975373 Process for the preparation of sulphur-containing hydrocarbon chains  
Process for the preparation of sulphur-containing hydrocarbon chains, which consists in producing a fermentative action of two types of bacteria, lactic bacteria and bacteria of the genus...
4975531 Sakyomicin E and the derivatives thereof, a process for the preparation thereof and the use thereof  
The compounds of the formula I ##STR1## in which R 1 to R 3 denote, independently of one another, hydrogen or a (C 1 -C 18 )-acyl group, and a process for the preparation thereof are described....
4973686 Process for the sulfonation and/or sulfatization of organic components with SO.sub.3 in an organic reaction medium  
The invention relates to the use of selected carboxylic acid esters which are liquid under reaction conditions and correspond to general formula (I) X--COOR 1 ...
4956459 Platinum compounds suitable for use as pharmaceuticals  
Compounds of the formula: ##STR1## wherein each of R 1 and R 2 is independently selected from the group consisting of halogen, hydroxy, or mono carboxylic acid or R 1 and R 2 together is a...
4954623 Recovery of difluoro sugar  
A process for recycling the difluoro sugar in the synthesis of 2,2-difluoronucleosides proceeds by removing the base moiety of α-difluoronucleosides by reduction and hydrolysis, followed by...
4950746 Process for synthesizing sucrose derivatives by regioselective reaction  
Sucrose is reacted with a 1,3-di(hydrocarbyloxy)-1,1,3,3-tetra(hydrocarbyl)distannoxan e to produce a 1,3-di-(6-O-sucrose)-1,1,3,3-tetra(hydrocarbyl)distannoxane, which can be acylated to produce...
4948883 Preparation of hydrogen and bismuth (phosph/sulf) ated saccharides  
Bismuth salts of phosphorylated and/or sulfonated saccharides are prepared from a corresponding metal salt reactant, a water soluble organic acid, and a bismuth substance. For example, a complex...
4948881 Process for the depolymerization and sulfation of polysaccharides  
Process for the depolymerization and sulfation of polysaccharides by reaction of said polysaccharides with a sulfuric acid/chlorosulfonic acid mixture.
4940786 One-pot preparation of bismuth (phosph/sulf)ated saccharides  
Bismuth salts of phosphorylated and/or sulfonated saccharides can be prepared in one reaction vessel from a corresponding metal salt reactant, a water soluble organic acid, and a bismuth substance....
4939244 Pseudoaglycones of LL-E33288 antibiotics  
Degradation products, termed pseudaglycones, of LL-E33288, BBM-1675, FR-900405, FR-900406, PD 114759, PD 115028, CL-1577A, CL-1577B, CL-1577D, CL-1577E and CL-1724 antibiotics/antitumor agents are...
4935503 Azidochlorination and diazidization of glycals  
The invention describes a one-pot single step procedure for the azidochlorination or diazidization of glycals, including glycal elements of carbohydrates. Compounds such as...
4935506 3-phenylthiosialic acid derivative, sialic acid-containing oligosaccharide derivative and process for preparing these compounds  
Sialic acid derivatives and process for preparing these compounds. In these compounds, a phenylthio group is stereo-selectively incorporated at the 3-position of the sialic acid. These compounds...
4921950 Preparation of 3'azido-3-'-deoxythymidine  
This invention relates to a new synthetic process for the manufacture of zidovudine from the starting material D-xylose involving: (i) Conversion of D-xylose to a 1-(β-D-xylofuranosyl)thymine...
4920207 Selected removal of trityl groups from trispa  
2,3,4,3',4'-penta-O-acetyl sucrose (4-PAS), a key intermediate in the preparation of sucralose, is prepared by the selective removal of trityl groups from 6,1', 6'-tri-O-trityl-penta-O-acetyl...
4918056 2-substituted arabinopyranosyl nucleosides and nucleotides  
Novel arabinopyranosyl nucleoside derivatives having the heterocyclic moiety and fluorine at the 2' position of the sugar ring (pyranose configuration), which have antitumor, antiviral and...
4918182 Sweetener  
Crystalline sucralose having a mean particle size of at most 10 microns, the maximum particle size being no more than twice the mean, exhibits enhanced stability to heat. Preferably the sucralose...
4916219 Oligosaccharide heparin fragments as inhibitors of complement cascade  
There is disclosed oligosaccharide compounds having heparin-like anticomplement activity and reduced anticoagulant activity as compared with heparin on a weight or molar basis. The oligosaccharide...
4916218 1-(β-D-xylofuranosyl)thymine derivatives  
This invention relates to a new synthetic process for the manufacture of zidovudine from the starting material D-xylose involving: (i) Conversion of D-xylose to a 1-(β-D-xylofuranosyl)thymine...
4914035 Process for producing sialic acid derivatives  
The present invention provides a process for selective production of a 2-α-O-glycoside compound of sialic acid which is useful as a starting material or intermediate for medicines and biochemical...
4914196 Complexes containing optically active sugar ligands, a process for their preparation and their use  
Compounds of the formulae I and Ia ##STR1## in which R 1 is a group which can be transferred to carbonyl or imine compounds, for example alkyl, allyl, vinyl or the radical of an enol or enamine, R...
4912204 Fluoro-substituted epipodophyllotoxin glucosides  
The present invention provides antitumor fluoro-substituted 4'-demethylepipodophyllotoxin glucosides.
4906579 New catalytically oxidized polyglucosic units and methods of making same leading to aldehyde groups on the C-6 position of polyglucosic product and new products therefrom  
A method to selectively oxidize a polyglucose, on the oxygen of the hydroxy groups of the C-6 position of the glucose rings, while substantially maintaining the degree of polymerization of the...
4900816 Hemoglobin complexes  
There is described a water soluble compound having a molecular weight of from about 70,000 to about 2,000,000 and having the formula I, B--X--(PS)--X--(H) ...
4889843 Salt of trisaccharide, and composition and process for re-stimulating hair growth  
The salt formed between the polyanions forming the Trichosaccharide and the NH 2 groups of 2,4-diamino-6-piperidino-pyrimidine-3-oxide represents a novel trichogenic factor by which the activity...
4889928 Sucrose alkyl 4,6-orthoacylates  
Sucrose 6-acylates, key intermediates in the preparation of sucralose, can be prepared by subjecting a sucrose alkyl 4,6-orthoacylate to mild aqueous acidic hydrolysis to provide a mixture of...
4871776 2,5-anhydro-1,6-dihalo-1,6-dideoxy-D-mannitol  
A novel fructose analog is disclosed which has been found to modify the food intake of mammals. If administered during the diurnal fasting period, the mammals increase their food intakes. If...
4855416 Method for the manufacture of dextran sulfate and salts thereof  
A method for the preparation of dextran sulfate and salts thereof which comprises first forming a complex between sulfur trioxide and formamide at a controlled temperature between 15°-40° C. in...
4847372 Process for the single-stage preparation of glycosyl fluorides  
A process for the single-stage preparation of glycosyl fluorides by dissolving saccharides in liquid hydrogen fluoride and evaporating the hydrogen fluoride, wherein the resulting glycosyl fluoride...
4826962 Tetrachlororaffinose and its use in the preparation of sucralose  
The novel chlorinated sugar O-α-D-6-chloro-6-deoxygalactopyranosyl-(1➝6)-α-D-4-chlo ro-4-deoxygalactopyranosyl-(1➝2)-β-D-1, 6-dichloro-1, 6-dideoxyfructofuranoside (TCR) can be used to...
4820692 Methylthioribose analogs, their preparation and use as medicinal agents and biocides  
Compounds of the formula: ##STR1## wherein R is H, Cl, F, Br, I or R 1 S--, in which R 1 is C 1 -C 10 linear or branched chain alkyl or halogenated linear or branched chain alkyl, and ...
4816573 Separation of carrageenan containing sea plants  
Sea plants containing kappa carrageenan are separated from those containing lambda carrageenan by subjecting a mixture of such plants to preferential hydration of the lambda plants without...
4810695 Chitosan derivatives in the form of coordinated complexes with ferrous ions  
Chitosan derivatives in the form of coordinated complexes with ferrous ions in which coordinated bonds are established between the ferrous ion and the amino group and hydroxyl group present...
4806275 Ionic derivatives of alkyl mono and polyglycosides  
New anionic derivatives of mono and polyglycosides which are surface-active agents are described which anionic derivatives have the general formula ##STR1## wherein G is a glycosyl moiety which is...
4801700 Process for the preparation of 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α -  
A process for the preparation of 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deo xy-α -galactopyranoside comprising the steps of (a) reacting sucrose with a tritylating agent; (b)...
4794178 Process for the production of .sup.18 F-labeled organic compounds by nucleophilic substitution  
Organic compounds labeled with no-carrier-added fluorine 18 are processed yield a compound having a formula in the form of 18 F-R through a nucleophilic substitution reaction. The process has a...
4783526 Chlorination of carbohydrates and other alcohols  
Chlorination of carbohydrates and alcohols utilizing a chlorinating reagent selected from triphenylphosphine oxide/thionyl chloride, thiphenylphosphine oxide/phosgene, triphenylphosphine...
Matches 151 - 200 out of 320 < 1 2 3 4 5 6 7 >