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4791104 |
Dihydrobenzothiophene and thiochromane aminoalcohols
The invention is concerned with dihydrobenzothiophene and thiochromane derivatives of the generic formula ##STR1## The compounds show anti-hypertensive, platelet aggregation inhibiting,...
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4781977 |
Cyclodextrin adsorbing-material
A cyclodextrin adsorbing material composed of a water-insoluble resin substrate to which a ligand having such a size as to be included by cyclodextrin is chemically bonded via a spacer radical; a...
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4777250 |
Chymotrypsin model
Low molecular weight chymotrypsin analogs exhibiting the binding and catalytic groups of the real enzyme of the formula ##STR1## where D equals α-, β- or γ-cyclodextrin; P is X or (CH 2 ) n X,...
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4774329 |
Controlled release agent for cetylpyridinium chloride
A complex of cyclodextrin and cetylpyridinium chloride is disclosed as a controlled release agent of cetylpyridinium chloride. The cyclodextrin can be either cyclodextrin molecule, a polymer of...
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4764604 |
Derivatives of gamma-cyclodextrin
This invention relates to γ-cyclodextrin ethers and mixed ethers wherein the ether substituents are C 1 -C 6 alkyl, hydroxy C 1 -C 6 alkyl, carboxy C 1 -C 6 alkyl or (C 1 -C 6 ...
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4754025 |
Glucosamine derivatives and reagent for assaying N-acetyl-β-D-glucosaminidase using the same as substrate
A glucosamine derivative is disclosed, represented by formula (I) ##STR1## wherein R 1 and R 2 independently represent a halogen atom or a nitro group. A reagent for assaying...
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4748237 |
Increasing cyclodextrin yields by the addition of various solutes to starch feedstocks
The yield of cyclodextrins formed in the hydrolysis of starch catalyzed by a cyclodextrin glycosyltransferase can be substantially increased by the addition of certain water-soluble solutes....
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4746734 |
Partially methylated cyclodextrins and process for producing the same
Partially methylated cyclodextrins with enhanced solubility in water have an average degree of methylation of hydroxyl groups at different positions in all the glucose units involved of about...
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4744975 |
6-iodoethylated starch and process for preparing the same
6-Iodoethylated starch and process for preparing the same are disclosed. The 6-idodethylated starch contains one iodine attached per 5 glucose units. Said compound is useful as a contrast agent for...
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4738923 |
Process for producing and separating cyclodextrins
The present invention is directed to the process of producing and separating cyclodextrins and in particular to the process of using food grade hydrocarbons that include a six membered ring having...
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4727064 |
Pharmaceutical preparations containing cyclodextrin derivatives
The invention comprises pharmaceutical preparations consisting generally of a drug with a substantially low water solubility and an amorphous, water-soluble cyclodextrin-based mixtures. In these...
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4722815 |
Process of making a synthetic resin product containing a molecular inclusion compound in cyclodextrin
A synthetic resin product contains various substances such as perfumes, insectifuges/insecticides, mold/mildew-proofing agents and anti-fungi agents which are inactivated by forming an inclusion...
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4711936 |
Curing agent for epoxy resin and method for curing epoxy resin
A curing agent for an epoxy resin comprises a cyclodextrin clathrate compound of a compound which is reactive with an epoxy group, a curing agent for an epoxy resin comprising a mixture of a...
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4707472 |
Cycloartenol ferulate/cyclodextrin complex
Cycloartenol ferulate/cyclodextrin complex is prepared by including cycloartenol ferulate, which is a component of γ-oryzanol and hardly soluble in water, with cyclodextrin to thereby elevate its...
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4696918 |
Solubilized platinum compound
The anti-cancer compound 1,1-cyclobutanedicarboxylatediammineplatinum(II) is rendered more water-soluble by formation of its inclusion compound with α-cyclodextrin.
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4689228 |
Enhanced absorption of dietary mineral components
Food supplement compositions for the enhanced absorption of nutrient mineral components additionally include a complex carbohydrate fraction, having an average molecular weight in the range from...
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4678598 |
Liquid shampoo composition
Novel liquid shampoo compositions comprise the following components (A), (B) and (C): (A) 5 to 30 wt % of at least one surface active agent, (B) 0.05 to 5 wt % of a skin sensation inducing...
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4677177 |
Rust preventive and method for producing the same
Maltooligosaccharide syrup is hydrogenated under nickel catalyst and high pressure so as to reduce the end-groups of the maltooligosaccharide syrup. The reduced syrup and cyclodextrin are mixed,...
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4675395 |
Cyclodextrin inclusion compound and process for its preparation
Hinokitiol, which is relatively insoluble in water, can be rendered more soluble by converting it to an inclusion compound in a cyclodextrin. This may be prepared by heating a mixture of hinokitiol...
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4668626 |
Method for the preparation of branched cyclodextrins
The invention provides an efficient enzymatic method for the preparation of branched cyclodextrins such as glucosyl and maltosyl cyclodextrins. The inventive method comprises the enzymatic reaction...
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4663316 |
Antibiotic clathrates and pharmaceutical compositions thereof
Cyclodextrin clathrates of certain unsaturated phosphorous containing antibiotics exhibit enhanced stability in pharmaceutical compositions.
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4638058 |
Ethers of beta-cyclodextrin and a process for their preparation
The novel water-soluble compounds are the ethyl ether and the N,N-dialkyl(C 1 to C 4 )aminoethyl ethers of β-cyclodextrin (β-CD). The process for the preparation of these ethers is performed by...
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4623641 |
Method of treating ulcers and erosions in the gastrointestinal system using PGI.sub.2 -methyl ester-beta cyclodextrin inclusion complexes
A new method is disclosed for the treatment and prevention of gastrointestinal ulcers or erosions which comprises the administration of a pharmaceutically effective amount of a PGI 2 methyl...
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4608366 |
Oral cyclodextrin and mobenzoxamine preparation
Disclosed herein is an oral mobenzoxamine preparation which comprises a clathrate compound of mobenzoxamine or a salt thereof and cyclodextrin. Since the clathrate compound remains extremely stable...
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4603123 |
Compounds having antiinflammatory activity, obtained by complexation of piroxican with β-cyclodextrin, and pharmaceutical compositions containing them
New inclusion compounds of 4-hydroxy-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carbox
yamide-1,1-dio xide with α, β or γ cyclodextrins, obtained by reaction of said cyclodextrins and said...
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4599327 |
Dibenzo[bd]pyran derivatives, process for the preparation thereof and pharmaceutical compositions containing same
2,6-di-O-methyl-beta-cyclodextrin complexes of compounds of the formula (1a) ##STR1## wherein R 2 ' stands for C 1 to C 12 alkyl or a group of the formula ##STR2## in which R 11 is C 1 to C 4 ...
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4598070 |
Tripamide and cyclodextrin inclusion compound
An inclusion compound composed of tripamide and cyclodextrin markedly improves the solubility of tripamide which is effective for treatment of essential hypertension.
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4596602 |
Method of preparing an aqueous maltodextrin solution having microbial stability and decreased haze
Method of making a stable aqueous maltodextrin solution containing maltodextrin, water and sorbic acid and a suitable food grade acid to adjust the pH to 2-4. The solution, preferably stored at an...
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4596795 |
Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives
The administration of sex hormones, particularly testosteorne, progesterone and estradiol in the form of their complexes or inclusions with specific derivatives of cyclodextrins by the sublingual...
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4585858 |
Starch-based polyether polyols
This application discloses polyether products of starch with several different etherifying agents, preferably the alkylene oxides, where the moles of etherifying agent per anhydroglucose unit are...
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4582900 |
Water-soluble mixed ethers of β-cyclodextrin and a process for their preparation
The invention relates to novel water-soluble mixed ethers of β-cyclodextrin (β-CD) with ether substituents comprising (C 1 and C 2 ) alkyl, hydroxy(C 2 to C 4 )alkyl and carboxy(C 1 and C 2...
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4575548 |
Occlusion compound of 2-nitroxymethyl-6-chloropyridine with β-cyclodextrin and process for preparation thereof
An occlusion compound of 2-nitroxymethyl-6-chloropyridine with β-cyclodextrin is disclosed herein as well as a process for preparing the occlusion compound thereof. The occlusion compound of the...
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4565807 |
Medicinal composition containing pirprofen and cyclodextrin and a method of use
The invention relates to a new medicinal composition containing α-[3-chloro-4-(3-pyrrolin-1-yl)-phenyl]-propionic acid as the pharmacologically active ingredient, having analgesic and...
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4563421 |
Method for determining the presence of endohydrolase in a liquid and composition therefor
What are disclosed are polysaccharide derivatives of the formula ##STR1## in which n denotes a number from 100 to 12,500 and R denotes hydrogen, a carboxyalkyl or hydroxyalkyl group with 1 to 5...
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4562204 |
Trans-Δ.sup.2 -prostaglandin D derivatives, process for their preparation and compositions containing them
Trans-Δ 2 -prostaglandin D derivatives of the formula: ##STR1## wherein [A] is a group of the formula: ##STR2## X is ethylene or cis-vinylene, C 13 -C 14 -C 15 is: (i) a group of the formula:...
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4555504 |
Inclusion complex of β-cyclodextrin and digoxin
Inclusion complexes of cyclodextrins, particularly β-cyclodextrin, and cardiac glycosides, particularly digoxin, are disclosed. The complexes have high aqueous solubility and are useful in the...
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4547572 |
Cyclodextrin polymers swelling quickly and to a great extent in water and process for the preparation thereof
The invention relates to cyclodextrin polymers swelling quickly and to a great extent in water and a process for the preparation thereof. The cyclodextrin polymers according to the invention...
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4542211 |
Process for the manufacture of heptakis-[2,6-di-O-methyl]-beta-cyclodextrin
The invention relates to a process for the manufacture of heptakis-[2,6-di-O-methyl]-beta-cyclodextrin by methylating beta-cyclodextrin in an organic phase wherein beta-cyclodextrin is methylated...
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4539399 |
Bonded phase material for chromatographic separations
A highly selective bonded phase material useful to separate a wide variety of organic and inorganic substances by thin layer chromatography (TLC), liquid chromatography (LC) or high performance...
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4535152 |
Water soluble cyclodextrin polymers substituted by ionic groups and process for the preparation thereof
The invention relates to water soluble cyclodextrin polymers substituted by ionic groups, containing structural units of formula (I) ##STR1##
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4524068 |
Cyclodextrin inclusion complex of piperonyl butoxide
The invention relates to new inclusion complexes of piperonyl butoxide formed with cyclodextrin. The new complex of the invention can be prepared by reacting cyclodextrin or a solution thereof...
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4518588 |
Process for the preparation of an inclusion complex of N-(1--phenylethyl)-3,3-diphenylpropylamine and the hydrochloride thereof respectively with cyclodextrin
An inclusion complex is disclosed of N-(1-phenylethyl)-3, 3-diphenyl-propylamine or its hydrochloride complexed with a cyclodextrin as well as a process for the preparation thereof and...
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4510166 |
Converted starches for use as a fat- or oil-replacement in foodstuffs
Converted starches, which with water form gels having a neutral taste and perferably a creamy, smooth consistency, are suitable as fat-and/or oil-replacements in various foodstuffs, especially high...
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4502930 |
Method for manufacture of 7-substituted quadricyclene-cyclodextrin inclusion compound
A 7-substituted quadricyclene-cyclodextrin inclusion compound is manufactured by irradiating a 7-substituted norbornadiene-cyclodextrin inclusion compound with light.
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4497803 |
Inclusion compound of lankacidin-group antibiotic and use thereof
Inclusion compound of lankacidin-group antibiotic with cyclodextrin, having enhanced water-solubility and stability and a veterinary composition containing the same, which is useful for curing...
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4479944 |
Composition containing PGI.sub.2 analogs stabilized
Compositions which contain a PGI 2 analogue in solution in a solvent consisting of at least one pharmacologically-acceptable alcohol, polar aprotic solvent or middle chain triglyceride, or which...
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4470975 |
Method and composition for the elimination of water from an animal body
It has been found that certain insoluble hydrophilic cross-linked polysaccharides are useful pharmaceutical agents in diverting water elimination from the renal route to the gastrointestinal route,...
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4451613 |
Ethylenically-unsaturated dextrin oligomers
A photocurable, ethylenically-unsaturated, water-soluble oligomer comprising the reaction product of 100 parts by weight of a dextrin compound, and 35 to 70 parts by weight of at least one...
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4443478 |
Prostaglandin analogues
Prostaglandin E 1 analogues of general formula: ##STR1## [wherein R 1 represents a bond or a straight- or branched-chain alkylene group containing from 1 to 5 carbon atom(s), and R 2 represents...
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4438106 |
Inclusion compound of eicosapentaenoic acid or docosahexaenoic acid with cyclodextrin
This disclosure describes an inclusion compound of cyclodextrin in which at least one guest compound selected from the group of eicosapentaenoic acid, docosahexaenoic acid and alkali metal salts...
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