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5756098 Methods for the extraction of phytochemicals from fibrous plants in the absence of solvent  
Methods and apparatus are provided for the recovery of organic compounds from fibrous plant materials. Organic compounds which can be recovered from the fibrous plant materials include plant...
5750678 Water-soluble dextran fatty acid esters and their use as solubilizers  
The invention relates to a water-soluble, haemolytically inactive dextran fatty carboxylate with amphiphilic properties made from a dextran with an average molecular weight of 5,000 to 100,000 and...
5744165 Nimesulide salt cyclodextrin inclusion complexes  
Inclusion complexes of nimesulide alkali and alkaline earth salts with cyclodextrins and cyclodextrin derivatives are disclosed. Compositions containing the inclusion complexes, processes for the...
5739121 Fluorocyclosaccharide drug delivery systems  
Novel fluorine-containing cyclic saccharide compounds, in particular fluorocyclodextrin compounds, and drug inclusion complexes of these compounds, as well as methods for preparation of the novel...
5734031 Cation exchange resin  
A new cation exchange resin is formed by mixing phytic acid with a material selected from the group consisting of polyhydroxy polymer, β-cyclodextrin and gluconic acid, and heating the mixture for...
5728823 Cyclodextrin derivatives having at least one nitrogen-containing heterocycle, their preparation and use  
Reactive cyclodextrin derivatives have at least one nitrogen-containing heterocycle. The reactive cyclodextrin derivatives include at least one nitrogen-containing heterocycle having at least one...
5728225 Viscous liquid compositions of xylitol and a process for preparing them  
The invention relates to viscous liquid compositions of xylitol which are noncrystallizable or which exhibit retarded crystallization, characterized by the fact that they contain: from 51% to...
5726161 Porous particle aggregate and method therefor  
The invention deals with porous aggregates and a process for making same. The aggregates generally comprise discrete particles which are bound together, the aggregates having intra-aggregate...
5723601 Super porous polysaccharide gels  
Porous material of a polysaccharide and a method for preparations of such a material, wherein a water-based solution of the polysaccharide is mixed, with controlled stirring, with an essentially...
5710268 Process for the preparation of methylated cyclodextrin derivatives, and their use as solubilizers  
A process in which α-, β- and/or γ-cyclodextrin are reacted in a suitable base, with a suitable O-alkylating agent and, where appropriate, following neutralization of the reaction mixture, the...
5698535 SIN-1A cyclodextrin inclusion complexes  
New inclusion complexes which are stable in their so-lid state formed of SIN-1A and cyclodextrins or cyclodextrin derivatives and optionally also containing ions as catalyst or stabilizer. The...
5696186 Process for improving the mutual compatibility of polymers  
A process for improving the mutual compatibility of natural and/or synthetic polymers by the use of cyclodextrin in the polymer mixture, wherein the cyclodextrin represents in particular from about...
5691316 Cyclodextrin cellular delivery system for oligonucleotides  
Disclosed is a composition including an oligonucleotide complexed with a cyclodextrin. The oligonucleotide may be noncovalently associated with the cyclodextrin. Alternatively, the oligonucleotide...
5681828 Selective alkylations of cyclodextrins leading to derivatives which have a rigidly extended cavity  
By controlling basicity of the reaction, it is possible to alkylate preferentially the secondary hydroxyls of cyclodextrins. These hydroxyls surround the principal, wide, entry into the...
5660845 Solid consumer product compositions containing small particle cyclodextrin complexes  
An effective amount of active/cyclodextrin complex, in the form of particles having particle sizes below about 12 microns, is incorporated into solid consumer product compositions. The complexes...
5658390 Purification of beta cyclodextrin  
A method for purifying non-branched beta cyclodextrin from aqueous solutions is disclosed. The process entails a plurality of independent crystallization steps.
5658894 Compositions for inhibiting restenosis  
Polyionic derivatives of cyclodextrins and methods for preparing these derivatives are provided in which a polyionic derivative of cyclodextrin is combined with a growth factor, preferably a...
5654422 Acylated γ-cyclodextrins  
Acylated cyclodextrins of the formula I: ##STR1## where R denotes hydrogen or R1, and R1 is identical or different and denotes acetyl, propionyl, butyryl, 2-alkoxyacetyl, 2-chloroacetyl,...
5646131 Method for solubilizing drugs using cyclodextrins and carboxylic acids  
A method for enhancing the solubilization and/or complexation of a drug which is insoluble or sparingly soluble in water with cyclodextrin, comprising combining the drug with cyclodextrin together...
5639824 Separating agent containing a support and a cyclodextrin derivative  
Chemically bonded bodies comprising a support and a cyclic oligosaccharide derivative, at least one of the 2-, 3- and 6-position hydroxyl groups of which is chemically bonded to the support through...
5637575 Methods of inhibiting restenosis  
Disclosed are compositions and methods effective for inhibiting restenosis. In particular, the present invention provides compositions for inhibiting undesired smooth muscle cell growth or...
5633368 Partially acylated β-cyclodextrins  
Partially acylated cyclodextrins of the formula I ##STR1## where R denotes hydrogen or R1, wherein R1 can be identical or different and denotes acetyl, propionyl, butyryl, 2-alkoxyacetyl,...
5631244 mono(6-amino-6-deoxy)cyclodextrin derivatives substituted in the 6-position by an α-amino acid residue, process for their preparation and their uses  
Mono (6-amino-6-deoxy)cyclodextrin derivatives substituted in the 6-position by an α-amino acid residue. These derivatives correspond to the following general formula: ##STR1## in which: CD...
5629090 Starch hydrolysates as sequesterers  
A starch hydrolysate composition is particularly suited for use as a sequesterer, i.e., it readily interacts noncovalently with other molecules to form stable inclusion complexes which are useful...
5624914 Lipophilic oligosaccharide antibiotic salt compositions  
Pharmaceutically acceptable compositions of matter comprising a lipophilic oligosaccharide antibiotic, e.g., the everninomicin-type antibiotic of Formula III, at least a stoichiometric amount of a...
5622844 Method of preparing a mannosyl-cyclodextrin  
A method of producing a mannosyl-cyclodextrin having a mannosyl group bonded to the hydroxyl group of the glucosyl group of a cyclodextrin via an alpha-bond. The method includes treating a liquid...
5623071 Galactosyl and mannosyl cyclodextrins  
A cyclodextrin having a galactosyl group which is bonded to a 6-hydroxyl group of a glucosyl group of the cyclodextrin via an α-bond or a β-bond; a cyclodextrin having a mannosyl group which is...
5620961 Fructose ester-β-cyclodextrin complexes and processes for making and using same  
A specialized derivative of fructose in which the compound is a fructose ester complexed with β-cyclodextrin. Preferably, the fructose derivative is fructosehexanoate β-cyclodextrin complex, and...
5620871 Process for preparing optionally hydrogenated indigestible polysaccharides  
The present invention relates to a process for preparing indigestible polysaccharides and to the corresponding hydrogenated products. This process essentially consists in carrying out an enzymatic...
5612321 Antioxidant grafted polysaccharides  
Grafted polysaccharide compositions comprising polysaccharides grafted with antioxidants on at least one hydroxyl group of the polysaccharide. The use of antioxidant grafted polysaccharides or...
5608052 Inclusioin complexes of clavulanic acid and of alkali salts thereof with hydrophilic and hydrophobic beta-cyclodextrin derivatives, a process for the preparation thereof and the use thereof  
Described is a new process for the preparation of alkali clavulanate from an aqueous solution of crude clavulanic acid, which is obtained in a conventional manner after the fermentation with a...
5608015 Processes for producing cyclodextrin derivatives and polymers containing immobilized cyclodextrin therein  
A process for producing a polymer containing immobilized cyclodextrin comprising reacting a cyclodextrin derivative with an acid halide monomer of an α,β-unsaturated acid or a derivative thereof...
5605892 Compositions of arginine amide with cyclodextrin of caffeine, and methods of use  
An aqueous agent comprising at least one arginine amide selected from the group consisting of (2R,4R)-4-methyl-1-[N 2 -((RS)-3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-ar ginyl]-2-piper...
5594125 Water-soluble cyclodextrin derivatives with lipophilic substituents and process for their preparation  
A water-soluble mixed ether of α-, β- or γ-cyclodextrin having at least one lipophilic and one hydrophilic radical per cyclodextrin molecule, of the following formula I: ##STR1## where R is...
5587466 Conductive polymer doped by a sulphonated cyclodextrin salt and device for obtaining and/or supplying an active substance incorporating said polymer  
Conductive polymer doped by a sulphonated cyclodextrin salt and device for obtaining and/or supplying an active substance incorporating said polymer. The dopant used has the following formula (I):...
5578585 Pleuromutilin derivative complexes  
Complexes and pharmaceutical preparations containing complexes of the pleuromutilin derivative of formula I ##STR1## in free base or in acid addition or quaternary salt form and cyclodextrin are...
5569756 Purification of chemically modified cyclodextrins  
Chemically modified cyclodextrins such as hydroxypropyl cyclodextrins are purified by treatment with an activated carbon made from either coal or coconut shells. The amount of activated carbon used...
5561116 Solid product containing propolis components, and preparation and uses thereof  
A solid, water-dispersible composition containing propolis components. This composition is prepared by extracting intact or dewaxed propolis with an aqueous solution of a water-soluble organic...
5556775 Method of producing β-cyclodextrin  
The present invention; is a method of producing β-cyclodextrin at a higher efficiency from a raw material other than starch, comprising making a malto-oligosaccharide with 2 to 10 glucoses...
5550222 Process for producing gamma-cyclodextrin  
A process for preparing cyclooctaamylose by enzymatic reaction of starch hydrolysate with cyclodextrin glycosyltransferase in the presence of at least two complexing agents. The first is either an...
5541202 New leukotriene-B4 Antagonists and their use as pharmaceutical agents  
1. Leukotriene-B 4 antagonists of formula I, ##STR1## are described, in which X represents C 1 -C 4 -alkoxy or --S(O) p --(C 1 -C 4 )-alkyl, p represents 0, 1 or 2 Y represents a hydrogen atom...
5538655 Molecular complexes for use as electrolyte components  
An molecular complex is provided which includes a linear polymer associated with a cyclic molecule to form a rotaxane of the general formula, ##STR1## where R 1 and R 2 are blocking end groups of...
5536826 Process for preparing amino-functional cyclodextrin derivative  
A process for preparing amino-functional cyclodextrin derivatives has an amino function which is linked to the cyclodextrin (CD) via a spacer. Compositions containing CD derivatives are prepared by...
5529915 Lyophilized polyethylene oxide modified protein and polypeptide complexes with cyclodextrin  
Disclosed are lyophilized biologically active proteinaceous compositions containing low diol polyalkylene oxide, such as polyethylene glycol, covalently attached to a biologically active...
5527783 Dry and Porous galenic form based on plants, its method of preparation and its applications  
Solid compositions based on plants, capable of being converted to a dry and porous galenic form (lyophilized or equivalent form) which is undivided or powdered. Said dry and porous galenic form...
5523218 Method of producing a galactosyl-cyclodextrin  
Disclosed are (1) a novel galactosyl-cyclodextrin having a galactosyl group as bonded to the hydroxyl group of the glucosyl group of a cyclodextrin via an α-bond and a method of producing said...
5519012 Inclusion complexes of optically active 1,4-dihydropyridines with methyl-β-cyclodextrin  
Novel inclusion complexes of racemic 1,4-dihydropyridines and enantiomers thereof of the formula ##STR1## wherein R represents a phenyl group, substituted with nitro, trifluoromethyl,...
5516766 Cyclodextrin polymers and cyclodextrins immobilized on a solid surface  
Polyionic derivatives of cyclodextrin polymers and cyclodextrins immobilized on a solid surface are disclosed. Compositions and methods for separating a molecular species, including but not limited...
5512290 Compositions containing 2-acetyl-1-pyrroline  
A powder-form composition of 2-acetyl-1-pyrroline incorporated with a support of maltodextrin and/or cyclodextrin. The composition is prepared by hydrolyzing a 2-(1-alkoxyethenyl)-1-pyrroline with...
5512665 Sulfonated compounds of β-cyclodextrin polymer and inhibitory drug for vascular wall hyperplasia containing the same  
This invention relates to sulfonates of β-cyclodextrin polymer having a sulfur content of 10% or more, which inhibit propagation of smooth muscle cells.