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5756098 |
Methods for the extraction of phytochemicals from fibrous plants in the absence of solvent
Methods and apparatus are provided for the recovery of organic compounds from fibrous plant materials. Organic compounds which can be recovered from the fibrous plant materials include plant...
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5750678 |
Water-soluble dextran fatty acid esters and their use as solubilizers
The invention relates to a water-soluble, haemolytically inactive dextran fatty carboxylate with amphiphilic properties made from a dextran with an average molecular weight of 5,000 to 100,000 and...
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5744165 |
Nimesulide salt cyclodextrin inclusion complexes
Inclusion complexes of nimesulide alkali and alkaline earth salts with cyclodextrins and cyclodextrin derivatives are disclosed. Compositions containing the inclusion complexes, processes for the...
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5739121 |
Fluorocyclosaccharide drug delivery systems
Novel fluorine-containing cyclic saccharide compounds, in particular fluorocyclodextrin compounds, and drug inclusion complexes of these compounds, as well as methods for preparation of the novel...
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5734031 |
Cation exchange resin
A new cation exchange resin is formed by mixing phytic acid with a material selected from the group consisting of polyhydroxy polymer, β-cyclodextrin and gluconic acid, and heating the mixture for...
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5728823 |
Cyclodextrin derivatives having at least one nitrogen-containing heterocycle, their preparation and use
Reactive cyclodextrin derivatives have at least one nitrogen-containing heterocycle. The reactive cyclodextrin derivatives include at least one nitrogen-containing heterocycle having at least one...
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5728225 |
Viscous liquid compositions of xylitol and a process for preparing them
The invention relates to viscous liquid compositions of xylitol which are noncrystallizable or which exhibit retarded crystallization, characterized by the fact that they contain: from 51% to...
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5726161 |
Porous particle aggregate and method therefor
The invention deals with porous aggregates and a process for making same. The aggregates generally comprise discrete particles which are bound together, the aggregates having intra-aggregate...
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5723601 |
Super porous polysaccharide gels
Porous material of a polysaccharide and a method for preparations of such a material, wherein a water-based solution of the polysaccharide is mixed, with controlled stirring, with an essentially...
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5710268 |
Process for the preparation of methylated cyclodextrin derivatives, and their use as solubilizers
A process in which α-, β- and/or γ-cyclodextrin are reacted in a suitable base, with a suitable O-alkylating agent and, where appropriate, following neutralization of the reaction mixture, the...
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5698535 |
SIN-1A cyclodextrin inclusion complexes
New inclusion complexes which are stable in their so-lid state formed of SIN-1A and cyclodextrins or cyclodextrin derivatives and optionally also containing ions as catalyst or stabilizer. The...
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5696186 |
Process for improving the mutual compatibility of polymers
A process for improving the mutual compatibility of natural and/or synthetic polymers by the use of cyclodextrin in the polymer mixture, wherein the cyclodextrin represents in particular from about...
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5691316 |
Cyclodextrin cellular delivery system for oligonucleotides
Disclosed is a composition including an oligonucleotide complexed with a cyclodextrin. The oligonucleotide may be noncovalently associated with the cyclodextrin. Alternatively, the oligonucleotide...
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5681828 |
Selective alkylations of cyclodextrins leading to derivatives which have a rigidly extended cavity
By controlling basicity of the reaction, it is possible to alkylate preferentially the secondary hydroxyls of cyclodextrins. These hydroxyls surround the principal, wide, entry into the...
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5660845 |
Solid consumer product compositions containing small particle cyclodextrin complexes
An effective amount of active/cyclodextrin complex, in the form of particles having particle sizes below about 12 microns, is incorporated into solid consumer product compositions. The complexes...
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5658390 |
Purification of beta cyclodextrin
A method for purifying non-branched beta cyclodextrin from aqueous solutions is disclosed. The process entails a plurality of independent crystallization steps.
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5658894 |
Compositions for inhibiting restenosis
Polyionic derivatives of cyclodextrins and methods for preparing these derivatives are provided in which a polyionic derivative of cyclodextrin is combined with a growth factor, preferably a...
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5654422 |
Acylated γ-cyclodextrins
Acylated cyclodextrins of the formula I: ##STR1## where R denotes hydrogen or R1, and R1 is identical or different and denotes acetyl, propionyl, butyryl, 2-alkoxyacetyl, 2-chloroacetyl,...
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5646131 |
Method for solubilizing drugs using cyclodextrins and carboxylic acids
A method for enhancing the solubilization and/or complexation of a drug which is insoluble or sparingly soluble in water with cyclodextrin, comprising combining the drug with cyclodextrin together...
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5639824 |
Separating agent containing a support and a cyclodextrin derivative
Chemically bonded bodies comprising a support and a cyclic oligosaccharide derivative, at least one of the 2-, 3- and 6-position hydroxyl groups of which is chemically bonded to the support through...
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5637575 |
Methods of inhibiting restenosis
Disclosed are compositions and methods effective for inhibiting restenosis. In particular, the present invention provides compositions for inhibiting undesired smooth muscle cell growth or...
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5633368 |
Partially acylated β-cyclodextrins
Partially acylated cyclodextrins of the formula I ##STR1## where R denotes hydrogen or R1, wherein R1 can be identical or different and denotes acetyl, propionyl, butyryl, 2-alkoxyacetyl,...
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5631244 |
mono(6-amino-6-deoxy)cyclodextrin derivatives substituted in the 6-position by an α-amino acid residue, process for their preparation and their uses
Mono (6-amino-6-deoxy)cyclodextrin derivatives substituted in the 6-position by an α-amino acid residue. These derivatives correspond to the following general formula: ##STR1## in which: CD...
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5629090 |
Starch hydrolysates as sequesterers
A starch hydrolysate composition is particularly suited for use as a sequesterer, i.e., it readily interacts noncovalently with other molecules to form stable inclusion complexes which are useful...
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5624914 |
Lipophilic oligosaccharide antibiotic salt compositions
Pharmaceutically acceptable compositions of matter comprising a lipophilic oligosaccharide antibiotic, e.g., the everninomicin-type antibiotic of Formula III, at least a stoichiometric amount of a...
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5622844 |
Method of preparing a mannosyl-cyclodextrin
A method of producing a mannosyl-cyclodextrin having a mannosyl group bonded to the hydroxyl group of the glucosyl group of a cyclodextrin via an alpha-bond. The method includes treating a liquid...
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5623071 |
Galactosyl and mannosyl cyclodextrins
A cyclodextrin having a galactosyl group which is bonded to a 6-hydroxyl group of a glucosyl group of the cyclodextrin via an α-bond or a β-bond; a cyclodextrin having a mannosyl group which is...
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5620961 |
Fructose ester-β-cyclodextrin complexes and processes for making and using same
A specialized derivative of fructose in which the compound is a fructose ester complexed with β-cyclodextrin. Preferably, the fructose derivative is fructosehexanoate β-cyclodextrin complex, and...
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5620871 |
Process for preparing optionally hydrogenated indigestible polysaccharides
The present invention relates to a process for preparing indigestible polysaccharides and to the corresponding hydrogenated products. This process essentially consists in carrying out an enzymatic...
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5612321 |
Antioxidant grafted polysaccharides
Grafted polysaccharide compositions comprising polysaccharides grafted with antioxidants on at least one hydroxyl group of the polysaccharide. The use of antioxidant grafted polysaccharides or...
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5608052 |
Inclusioin complexes of clavulanic acid and of alkali salts thereof with hydrophilic and hydrophobic beta-cyclodextrin derivatives, a process for the preparation thereof and the use thereof
Described is a new process for the preparation of alkali clavulanate from an aqueous solution of crude clavulanic acid, which is obtained in a conventional manner after the fermentation with a...
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5608015 |
Processes for producing cyclodextrin derivatives and polymers containing immobilized cyclodextrin therein
A process for producing a polymer containing immobilized cyclodextrin comprising reacting a cyclodextrin derivative with an acid halide monomer of an α,β-unsaturated acid or a derivative thereof...
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5605892 |
Compositions of arginine amide with cyclodextrin of caffeine, and methods of use
An aqueous agent comprising at least one arginine amide selected from the group consisting of (2R,4R)-4-methyl-1-[N 2 -((RS)-3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-ar
ginyl]-2-piper...
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5594125 |
Water-soluble cyclodextrin derivatives with lipophilic substituents and process for their preparation
A water-soluble mixed ether of α-, β- or γ-cyclodextrin having at least one lipophilic and one hydrophilic radical per cyclodextrin molecule, of the following formula I: ##STR1## where R is...
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5587466 |
Conductive polymer doped by a sulphonated cyclodextrin salt and device for obtaining and/or supplying an active substance incorporating said polymer
Conductive polymer doped by a sulphonated cyclodextrin salt and device for obtaining and/or supplying an active substance incorporating said polymer. The dopant used has the following formula (I):...
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5578585 |
Pleuromutilin derivative complexes
Complexes and pharmaceutical preparations containing complexes of the pleuromutilin derivative of formula I ##STR1## in free base or in acid addition or quaternary salt form and cyclodextrin are...
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5569756 |
Purification of chemically modified cyclodextrins
Chemically modified cyclodextrins such as hydroxypropyl cyclodextrins are purified by treatment with an activated carbon made from either coal or coconut shells. The amount of activated carbon used...
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5561116 |
Solid product containing propolis components, and preparation and uses thereof
A solid, water-dispersible composition containing propolis components. This composition is prepared by extracting intact or dewaxed propolis with an aqueous solution of a water-soluble organic...
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5556775 |
Method of producing β-cyclodextrin
The present invention; is a method of producing β-cyclodextrin at a higher efficiency from a raw material other than starch, comprising making a malto-oligosaccharide with 2 to 10 glucoses...
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5550222 |
Process for producing gamma-cyclodextrin
A process for preparing cyclooctaamylose by enzymatic reaction of starch hydrolysate with cyclodextrin glycosyltransferase in the presence of at least two complexing agents. The first is either an...
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5541202 |
New leukotriene-B4 Antagonists and their use as pharmaceutical agents
1. Leukotriene-B 4 antagonists of formula I, ##STR1## are described, in which X represents C 1 -C 4 -alkoxy or --S(O) p --(C 1 -C 4 )-alkyl, p represents 0, 1 or 2 Y represents a hydrogen atom...
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5538655 |
Molecular complexes for use as electrolyte components
An molecular complex is provided which includes a linear polymer associated with a cyclic molecule to form a rotaxane of the general formula, ##STR1## where R 1 and R 2 are blocking end groups of...
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5536826 |
Process for preparing amino-functional cyclodextrin derivative
A process for preparing amino-functional cyclodextrin derivatives has an amino function which is linked to the cyclodextrin (CD) via a spacer. Compositions containing CD derivatives are prepared by...
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5529915 |
Lyophilized polyethylene oxide modified protein and polypeptide complexes with cyclodextrin
Disclosed are lyophilized biologically active proteinaceous compositions containing low diol polyalkylene oxide, such as polyethylene glycol, covalently attached to a biologically active...
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5527783 |
Dry and Porous galenic form based on plants, its method of preparation and its applications
Solid compositions based on plants, capable of being converted to a dry and porous galenic form (lyophilized or equivalent form) which is undivided or powdered. Said dry and porous galenic form...
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5523218 |
Method of producing a galactosyl-cyclodextrin
Disclosed are (1) a novel galactosyl-cyclodextrin having a galactosyl group as bonded to the hydroxyl group of the glucosyl group of a cyclodextrin via an α-bond and a method of producing said...
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5519012 |
Inclusion complexes of optically active 1,4-dihydropyridines with methyl-β-cyclodextrin
Novel inclusion complexes of racemic 1,4-dihydropyridines and enantiomers thereof of the formula ##STR1## wherein R represents a phenyl group, substituted with nitro, trifluoromethyl,...
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5516766 |
Cyclodextrin polymers and cyclodextrins immobilized on a solid surface
Polyionic derivatives of cyclodextrin polymers and cyclodextrins immobilized on a solid surface are disclosed. Compositions and methods for separating a molecular species, including but not limited...
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5512290 |
Compositions containing 2-acetyl-1-pyrroline
A powder-form composition of 2-acetyl-1-pyrroline incorporated with a support of maltodextrin and/or cyclodextrin. The composition is prepared by hydrolyzing a 2-(1-alkoxyethenyl)-1-pyrroline with...
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5512665 |
Sulfonated compounds of β-cyclodextrin polymer and inhibitory drug for vascular wall hyperplasia containing the same
This invention relates to sulfonates of β-cyclodextrin polymer having a sulfur content of 10% or more, which inhibit propagation of smooth muscle cells.
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