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7605239 |
Skeletal-targeted radiation to treat bone-associated pathologies
The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases,...
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7601859 |
Organometallic complexes
Organometallic complexes comprising a trivalent lanthanide metal ion complexed with one or more polydentate ligands containing one or more pyrazolyl-derived groups, such as trispyrazolyl borate...
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7595414 |
Metal complex compound comprising β-diketonato ligand
To provide a metal complex compound capable of being suitably used for manufacturing a metal-containing thin film by the CVD method and a method for preparing a metal-containing thin film. A metal...
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7575253 |
Fluorescent image-printed article and fluorescent ink
A fluorescent image-printed article including a substrate, and an image formed on the substrate, wherein the image is formed from a fluorescent ink containing a binder, and a fluorescent substance...
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7572731 |
Unsymmetrical ligand sources, reduced symmetry metal-containing compounds, and systems and methods including same
The present invention provides metal-containing compounds that include at least one β-diketiminate ligand, and methods of making and using the same. In some embodiments, the metal-containing...
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7570411 |
Optical limiter having trimetallic nitride endohedral metallofullerence films
An exemplary optical limiter device ( 100 ) has an optically transmissive substrate ( 102 ) and a layer ( 104 ) on a first surface ( 106 ) of the substrate, the layer having a trimetallic nitride...
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7524483 |
Responsive paramagnetic MRI contrast agents
A method is claimed based on CEST procedure for the in vivo or in vitro determination of physical or chemical parameters which includes the use of a responsive paramagnetic CEST contrast agent.
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7521551 |
Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy
The present invention provides a process of preparation of naphthochlorins and other chlorins with annelated ring systems useful for photodynamic therapy and the compounds themselves. The method...
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7517701 |
Luminescent lanthanide complexes
Systems, including compositions, kits, and methods, particularly for photoluminescence applications. The systems may include, among others, (1) organic chelators, (2) complexes between the...
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7514577 |
Pd- and Pt-substituted polyoxometalates and process for their preparation
The invention relates to polyoxometalates represented by the formula (A n ) m+ [M y (H 2 O) (p.y) X 2 W 22 O 74 (OH) 2 ] m− or solvates or mixtures thereof, wherein A represents a cation, n is...
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7456215 |
Pharmaceutical gallium compositions and methods
Novel pharmaceutical gallium compositions, including gallium complexes having increased oral bioavailablity relative to uncomplexed gallium salts are disclosed. Such compositions are useful in the...
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7439338 |
Beta-diketiminate ligand sources and metal-containing compounds thereof, and systems and methods including same
The present invention provides metal-containing compounds that include at least one β-diketiminate ligand, and methods of making and using the same. In certain embodiments, the metal-containing...
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7438893 |
Polybiotin compounds for magnetic resonance imaging and drug delivery
The invention relates generally to biotin-containing compounds that are useful as imaging agents and drug-delivery agents. Another aspect of the invention relates to the aforementioned compounds...
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7429294 |
Color compositions
The present invention includes a paint or coating composition comprising an organic pigment or dye complexed to the surface of a layered or fibrous inorganic clay. A wide variety of paint colors...
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7425235 |
Color compositions and methods of manufacture
The present invention includes a paint or coating composition comprising an organic pigment or dye complexed to the surface of a layered or fibrous inorganic clay. A wide variety of paint colors...
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7408046 |
Treatment of bone-associated cancers
The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases,...
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7399460 |
Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
Diagnostic and therapeutic compositions in the form of complexes for enhancing transmembrane transport of a diagnostic or therapeutic agent and methods for their use. The complexes contain the α,...
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7390861 |
Cationic group-3 catalyst system
A cationic Group 3 or Lanthanide metal complex for coordination polymerization of olefins is disclosed. The precursor metal complex is stabilized by an anionic multidentate ancillary ligand and two...
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7388082 |
Alkoxyalcohol adduct of rare earth monocarboxylate
An alkoxyalcohol adduct of rare earth monocarboxylate has the formula (I):
M(R 2 —COO) 3 .(R 1 O(CH 2 ) n OH) p ...
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7378077 |
High dose radionuclide complexes for bone marrow suppression
The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases,...
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7371742 |
Porphyrin derivatives for photodynamic therapy
This invention relates to porphyrin compounds used to destroy or impair the functioning of a target biological material in photodynamic therapy, in particular against virus, tumoral cells,...
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7358380 |
Ru-substituted polyoxometalates and process for their preparation
The invention relates to polyoxometalates represented by the formula (A n ) m+ [R 2 (H 2 O) 6 X 2 W 20 O 70 ] m− or solvates thereof, wherein A represents a cation, n is the number of the...
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7358343 |
Endohedral metallofullerene derivatives
Trimetallic nitride endohedral metallofullerene derivatives and their preparation are described. The trimetallic nitride endohedral metallofullerene derivatives have the general formula A 3-n X n...
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7323581 |
Source reagent compositions and method for forming metal films on a substrate by chemical vapor deposition
A metalorganic complex composition comprising a metalorganic complex selected from the group consisting of: metalorganic complexes comprising one or more metal central atoms coordinated to one or...
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7321027 |
Small technetium-99m and rhenium labeled agents and methods for imaging tumors
The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tumors, e.g., carcinomas, melanomas and...
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7312251 |
Synthesis of stable solutions of rare earth tris (organophosphate) in hydrocarbon solvents
Stable rare earth tris (organophosphate) solutions comprise a rare earth tris (organophosphate) and a hydrocarbon solvent. From about 2% to about 10% rare earth element, preferably from about 3% to...
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7309567 |
Method for reducing fluorescence quenching in bioassays
The invention relates to a process for reducing the fluorescence quenching caused by the measuring medium, in a fluorescence assay for an analyte using at least one fluorescent label, characterized...
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7279234 |
Methods for identity verification using transparent luminescent polymers
Disclosed are methods of using a transparent, luminescent polymer for transparent marking and/or labeling for identity verification purposes. Also disclosed are sheets, films, markers, labels and...
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7276494 |
Photosensitisers
A compound for use as a photosensitiser in PDT, in photochemical internalisation in the production of a cancer vaccine or in the diagnosis or detection of medical conditions, the compound having a...
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7268220 |
Bridged aromatic substituted amine ligands with donor atoms
The present invention provides for substituted metal chelating compounds in which at least two of the chelating atoms are nitrogen which are directly attached to aromatic rings and one or more of...
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7244841 |
Porphyrin derivatives and their use in photodynamic therapy
A compound of formula I:
wherein X 1 , X 2 , X 3 , X 4 , Y 1 , Y 2 , Y 3 , Y 4 and Z have meanings given in the description, and metallated forms of such compounds, which are useful in the...
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7238818 |
Heterocyclic metallocenes and polymerization catalysts
A new class of heterocyclic metallocenes, a catalytic system containing them and a process for polymerizing addition polymerizable monomers using said catalytic system are disclosed; the...
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7238339 |
Bifunctional chelating compounds containing hydroxamic acid residues
New types of hydroxamic acid-based bifunctional chelators are provided. These chelators are designed to chelate metal ions that can be detected either by their paramagnetic or radioactive...
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7211241 |
Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes
Described are new cascade polymer complexes, compositions containing them and use of the complexes in diagnosis and therapy, particularly for magnetic resonance imaging and computer tomography...
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7211235 |
Method for producing hydrotalcites
A method is described for the manufacture of hydrotalcites by using at least one compound of a bivalent metal (Component A) and at least one compound of a trivalent metal (Component B), wherein at...
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7196210 |
Isoreticular metal-organic frameworks, process for forming the same, and systematic design of pore size and functionality therein, with application for gas storage
The ability to design and construct solid-state materials with pre-determined structures is a grand challenge in chemistry. An inventive strategy based on reticulating metal ions and organic...
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7192650 |
Element having porphyrin polymer fixed on a substrate and method of preparing the same
A photo-functional molecule element having, on a substrate, a porphyrin polymer containing covalently-fixed porphyrin units, and the method of preparing the same. The photo-functional molecule...
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7186400 |
Multidentate aza ligands able to complex metal ions and the use thereof in diagnostics and therapy
Compounds of general formula (I): in which: R 1 is hydrogen, C 1 –C 20 alkyl, C 3 –C 10 cycloalkyl, C 4 –C 20 cycloalkylalkyl, aryl, arylalkyl, or two R1, taken together, form a straight...
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7160873 |
Texaphyrin coordination compounds and uses thereof
Novel coordination polymers, their pharmaceutical formulations, useful for treating atheroma, tumors and other neoplastic tissue, as well as other conditions that are responsive to the induction of...
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7153956 |
Cyanine dye having multifunctional peripheral groups
The present invention provides an IR-absorbing dye of formula (I) or (II)
wherein
R 10 , R 13 , R 20 , R 23 , R 30 , R 33 , R 40 and R 43 are independently selected from a C 1-12 alkyl...
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7148367 |
Organometallic compound, its synthesis method, and solution raw material and metal-containing thin film containing the same
The organometallic compound of the present invention is a compound that has bonds between metal atoms and nitrogen atoms or bonds between semimetal atoms and nitrogen atoms, and the content of...
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7148345 |
Synthetically expedient water-dispersible IR dyes having improved lightfastness
The present invention provides an IR-absorbing naphthalocyanine dye of formula (I):
wherein
M is selected from Ga(A 1 ); A 1 is an axial ligand selected from —OH, halogen (preferably Cl),...
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7148174 |
Non-metallocene catalyst system
The present invention describes a novel group of specific transition metal compounds, referred to as nonmetallocene compounds, and catalyst systems prepared therefrom. These catalyst systems which...
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7147840 |
Oxo-bacteriopyropheophorbide-a carboxylic acid and esters thereof
A compound having the structural formula:
where R is H or lower alkyl of 1 through 12 carbon atoms. In general, the compounds of the invention are 13 2 -Oxo-bacteriopyropheophorbide—a...
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7147837 |
Bioactivated diagnostic imaging constrast agents
The present invention relates to improved diagnostic agents for Magnetic Resonance Imaging and optical imaging. In particular, this invention relates to MRI and optical imaging agents that allow...
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7138391 |
Hydrophilizable and hydrophilic cyanine dyes
The present invention provides an IR-absorbing dye of formula (I) or (II):
wherein
Q 1 , Q 2 , Q 3 and Q 4 are the same or different and are independently selected from a C 3-20 ...
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7125965 |
MRI probes of membrane potential
The invention provides methods and compositions for molecular resonance imaging of membrane potential. The compositions comprise an indicator moiety attached through an optional linker to a...
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7125862 |
Porphyrin-metal complexes and oxygen infusions containing the same
A porphyrin metal complex that can form a stable oxygen complex and acts effectively as an oxygen infusion, which comprises:
a transition metal ion M of period 4 or 5 coordinating to a porphyrin...
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7122643 |
Cytostatic lanthanum compounds
Lanthanum compounds are provided having general formulas (I) R n i+ Y i n− and (II) R b + Y b − which may be used as medicaments in the prophylaxis and/or treatment of cancer diseases. In...
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7122076 |
Synthetically expedient water-dispersible IR dyes
The present invention provides an IR-absorbing naphthalocyanine dye of formula (I):
wherein
M is selected from Si(A 1 )(A 2 ), Ge(A 1 )(A 2 ), Ga(A 1 ), Mg, Al(A 1 ), TiO, Ti(A 1 )(A 2...
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