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7569671 |
Method and system for corn fractionation
Methods and apparatus for processing corn into one or more corn products. Oil is extracted from corn or corn products or by-products with a solvent. The corn-solvent mixture is separated into...
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7556835 |
High efficiency protein extraction
The invention relates to a process for isolating edible protein from animal muscle by solubilizing the protein in an alkaline aqueous solution.
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7482162 |
Determination of vitamin D metabolite and displacement from plasma or serum binding proteins
We disclose methods for measuring vitamin D metabolite in plasma or serum samples. The methods comprise a step of adding to the plasma or serum samples a non-competitive displacement agent...
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7470778 |
Use of ionic liquids for protein extraction
The present invention relates to a method for the extraction of proteins, protein fragments and/or peptides from biological samples, where the extractants employed are ionic liquids of the general...
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7365173 |
Method for the production of pure virally inactivated butyrylcholinesterase
The present invention provides a method for purifying butyrylcholinesterase from various biological fluids. Biological fluids include, e.g., blood, blood fractions, plasma, and bioreactor broths,...
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7358342 |
Preparation derived from shark cartilage for treatment of diseased related to excessive PHF or excessive intracellular calcium
A preparation derived from shark cartilage for the treatment of diseases related to excessive PHF or Excessive intracellular calcium.
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7335739 |
Methods for the purification and aqueous fiber spinning of spider silks and other structural proteins
Methods are described for the purification and spinning of recombinant and non-recombinant proteins. Specifically, the lysis of bacteria and purification of silk proteins occur in a single solution...
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7229789 |
Methods and compositions for extracting proteins from cells
A process is disclosed for releasing proteins from cells and/or inactivating viruses. In the process, a host cell containing a protein of interest is contacted with a solution of an effective...
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7193056 |
Process for purifying a compound
The present invention relates to a process for purifying a hydrophobic or amphiphilic compound, by first mixing a starting material containing the hydrophobic or amphiphilic compound with a first...
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7098026 |
Human desert hedgehog protein
Disclosed are a novel hedgehog protein, i.e., a Desert hedgehog protein of human origin including mature and precursor forms, a DNA encoding the protein, a monoclonal antibody recognizing the...
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7067639 |
Method to provide bacterial ghosts provided with antigens
Methods for improving binding of a proteinaceous substance to cell-wall material of a Gram-positive bacterium are disclosed. The proteinaceous substance includes an AcmA cell-wall binding domain,...
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7048930 |
Expression of core-glycosylated HCV envelope proteins in yeast
The present invention relates to the general field of recombinant protein expression, purification of recombinant proteins, diagnosis of HCV infection, prophylactic treatment against HCV infection...
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7019120 |
Cloud-point extraction of enzymes and polypeptides from a fermentation broth using a non-ionic surfactant
A method of extracting a polypeptide of interest from a fermentation broth comprising:
i) adjusting the pH close to pI of the polypeptide of interest; ii) adding a non-ionic surfactant with...
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6994847 |
Stabilized interferon compositions
Stabilized pharmaceutical formulations comprising IFN-β and highly purified mannitol are provided. The highly purified mannitol stabilizes the compositions by reducing the formation of IFN-β...
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6967241 |
Process for protein extraction
The invention includes a process for extracting a target protein from E. coli cells that includes lowering the pH of a whole E. coli cell solution to form an acidic solution, disrupting the...
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6967239 |
Method of filtering viruses from a factor VIII solution
Method for preparing a factor VIII solution that is essentially free of viruses and essentially devoid of vWF (von Willebrand factor) and factor VIII-vWF complexes by (a) obtaining a starting...
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6924267 |
Methods and active substances for protecting organs
The present invention comprises a method of protecting organs or tissue susceptible to reperfusion-induced dysfunction after ischemia. The method comprises parenterally administering to a patient a...
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6916914 |
Purification of somatotropin from transformed microorganisms
This invention discloses a commercially advantageous process for extraction and purification of protein from microorganisms. The initial steps of the process are useful for purifying many insoluble...
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6894023 |
Growth hormone crystals and a process for production of these GH-crystals
A process for producing cation crystals of growth hormone or growth hormone derivatives, as well as growth hormone and growth hormone derivatives. The process of producing the growth hormone...
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6894029 |
Use of jellyfish collagen (type II) in the treatment of rheumatoid arthritis
Compositions of substantially homogeneous type II-like collagen from invertebrates belonging to the class Scyphozoa, phylum Coelenterata, i.e., jellyfish, particularly Stomolophus meleagris , and...
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6861505 |
Method for recovering soluble protein
The present invention relates in providing a process for recovering a soluble protein having a higher recovery rate by suppressing the aggregation of the protein when a denaturing agent is removed...
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6852833 |
Artificial chaperon kit
The present invention provides an artificial chaperon useful for refolding the proteins having low voluntary folding ability and being difficult or unable to be a native form without a second (or...
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6844424 |
Method for obtaining avian biological products
This invention provides a method for separating and extracting biological products of avian origin. The method allows for the production of avian cartilages and of active ingredients which can be...
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6844321 |
Crystallization of a GLP-1 analogue
Crystals of glucagon-like peptide-1 (GLP-1) and GLP-1 analogues, and processes for preparation of crystals of GLP-1 and GLP-1 analogues.
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6844427 |
Method for removing the transforming growth factor-β by adsorption
An adsorbent suitable for adsorption of a transforming growth factor-β (TGF-β) comprising a compound which has a log P value of at least 2.50 wherein P is a partition coefficient in an...
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6821752 |
Methods and compositions for extracting proteins from cells
The present invention relates to a process of releasing a protein, recombinant or otherwise, from a cell. The process of the present invention involves contacting a host cell containing a protein...
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6803454 |
Method for extraction and purification of cartilage type proteoglycan
The present invention relates to a new method for extraction and purification of cartilage type proteoglycan, and is to provide a method for extraction of crude proteoglycan characterizing to use...
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6756484 |
IGF-I purification process
Disclosed is an improved process for obtaining purified, monomeric, intact, correctly-folded insulin-like growth factor-I (also known as somatomedin-C). The improvements, consisting primarily of...
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6756041 |
Process for preparing conjugate vaccines including free protein and the conjugate vaccines, immunogens, and immunogenic reagents produced by this process
A process for preparing a protein-polysaccharide conjugate includes reacting a protein with a polysaccharide to produce a mixture including a protein-polysaccharide conjugate and free protein. At...
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6756482 |
Purified human activin and process for producing the same
The present invention provides a process for purifying human activin by cation exchange chromatography and chaotropic ion concentration gradient elution.
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6686456 |
Method for the elimination of Kunitz and Bowman-Birk trypsin inhibitors and carboxypeptidase inhibitor from potato proteins
A method for removing protein impurities from extracts of protease inhibitor-containing plant material. Plant materials containing protease inhibitors, such a potato tubers that contain protease...
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6686455 |
Tumor necrosis factor
A cytotoxic protein designated tumor necrosis factor is identified in nature. It is recovered in substantially homogeneous form by treatment with hydrophobic substances and ion exchange resins. The...
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6649740 |
Hydratable form of keratin for use as a soil amendment
A hydratable oxidized keratin composition comprising one or more metal ion species capable of absorbing water to form a hydrogel. The keratin material is useful as a soil amendment providing...
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6638749 |
Carbon dioxide soluble surfactant having two fluoroether CO2-philic tail groups and a head group
There is provided a process for the extraction of water soluble biomaterials such as enzymes or proteins into carbon dioxide utilizing certain carbon dioxide-soluble surfactants. Also provided are...
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6635285 |
Shark cartilage extract: process of making, methods of using, and compositions thereof
The present invention relates to cartilage extracts and to a method of producing the same. Shark cartilage extracts having anti-angiogenic, anti-tumor, anti-inflammatory and anti-collagenolytic...
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6635746 |
Chlamydial vaccines and immunogenic compositions containing an outer membrane antigen and methods of preparation thereof
Immunogenic compositions including vaccines are described that comprise an outer membrane antigen extract of a strain of Chlamydia and are effective in protection against disease caused by...
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6620917 |
Method for the purification and aqueous fiber spinning of spider silks and other structural proteins
Methods are described for the purification and spinning of recombinant and non-recombinant proteins. Specifically, the lysis of bacteria and purification of silk proteins occur in a single solution...
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6610831 |
Methods and apparatus for recovering zein from corn
Methods and apparatus for recovering zein from substrates are disclosed. The method includes extracting a zein-containing substrate such as whole corn with ethanol to yield a crude zein alcoholic...
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6602985 |
Extraction of zein protein from gluten meal
Zein is recovered from gluten meal prepared by wet milling procedures by washing the gluten with clean water to remove water-soluble components; separating the water-soluble components and...
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6566329 |
Freeze-dried preparation of human growth hormone
A readily-soluble freeze-dried solid preparation of hGH with a minimal content of degradation products in terms of deamidation, dimers, polymers, and sulphoxide forms, obtainable by a method...
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6562952 |
Precipitation of proteins from organic solutions
A process for forming small micron-sized (1-10 μm) protein particles is provided wherein a protein, a solvent system for the protein and an antisolvent for the protein solvent system are contacted...
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6562951 |
Method of solubilization and naturation of somatotropins
A method for the solubilization and/or naturation of a somatotropin involves contacting a somatotropin with a detergent composition and water under conditions effective to obtain a naturated...
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6562605 |
Extraction of water soluble biomaterials from fluids using a carbon dioxide/surfactant mixture
A method is provided for the extraction of water soluble biomaterials such as enzymes or proteins into carbon dioxide utilizing certain carbon dioxide soluble surfactants. The extraction can be...
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6559284 |
Process for purifying a protein
The present invention relates to a composition for use in purification of apolipoprotein A (ApoA) or apolipoprotein E (ApoE), said composition comprising a first and a second polymeric material,...
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6468733 |
Method of the inactivation of viruses by a solvent-detergent combination and nanofiltration
The invention concerns a method for elimination of viruses from a biological preparation wherein initially enveloped viruses are eliminated by a solvent-detergent step, then the solvent-detergents...
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6454950 |
Separation method utilizing liquid-liquid partition
A method for the separation of a predetermined compound comprising i) partitioning the compound in a two-phase (system A) in which at least one of the phases is rich (phase 1 ) and the other is...
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6444211 |
Purification of a pertussis outer membrane protein
Pertactin (formerly 69 kDa protein) is recovered in stable biologically pure form having no detectable adenylate cyclase activity from fermentation broth from the fermentation of Bordetella...
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6437102 |
Method of separating prions from biological materials
Disclosed is a method for separating prions from biological materials. The method includes adding a polyalkylene glycol, such as polyethylene glycol, to a solution of the biological material such...
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6433146 |
Corn oil and protein extraction method
The invention is a corn product removal process that successfully extracts oil and zein from dry-milled corn. Oils and zein are extracted from corn using ethanol. Corn solids are separated from the...
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6414124 |
Methods for the isolation of proteinase inhibitor proteins from potato tubers
A rapid and simple method of isolating heat stable proteinase inhibitor proteins from plant tissues such as potato tubers is disclosed. The method comprises three steps. Proteins from potato tubers...
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