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7601515 |
Process of high purity albumin production
A process is provided for the preparation of albumin from a yeast culture medium which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, host proteins,...
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7498412 |
Process for preparing porous collagen matrix from connective tissue
The subject invention provides a process for preparing a porous collagen matrix from connective tissue, said process comprising: a porous structure forming step to treat said connective tissue with...
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7439336 |
Process for the purification of IL-18 binding protein
The invention relates to a process for the purification of IL-18 binding protein (IL-18BP) from a fluid using aqueous two-phase partitioning.
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7381789 |
Synthesis of inorganic structures using templation and catalysis by self assembled repeat protein polymers
Methods for forming repeat protein polymers and utilizing the repeat protein polymers to form inorganic structures are provided. The inorganic structures may have features on the nanoscale, and the...
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7262058 |
Method for determining lipid associated sialoprotein in body fluids
The amount of lipid associated sialoprotein (LSP) in body fluids such as cerebrospinal fluid, peritoneal fluid, pleural fluid, bronchial washings, saliva and sputum samples, may be determined by a...
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7232894 |
Method for the production of recombinant peptides with a low amount of trisulfides
Methods for the production of recombinant peptides comprise fermenting cells to produce recombinant peptides. A metal salt is added to a concentrate of the fermented cells after the fermentation...
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7223561 |
Process of high purity albumin production
A process is provided for the preparation of albumin which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, host proteins, fragments of albumin, polymers...
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6998251 |
Nanoporous membrane reactor for miniaturized reactions and enhanced reaction kinetics
Reactors and methods for miniaturized reactions having enhanced reaction kinetics. In particular the subject matter is directed to chemical and biological reactions conducted in a nanoporous...
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6967239 |
Method of filtering viruses from a factor VIII solution
Method for preparing a factor VIII solution that is essentially free of viruses and essentially devoid of vWF (von Willebrand factor) and factor VIII-vWF complexes by (a) obtaining a starting...
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6894023 |
Growth hormone crystals and a process for production of these GH-crystals
A process for producing cation crystals of growth hormone or growth hormone derivatives, as well as growth hormone and growth hormone derivatives. The process of producing the growth hormone...
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6875617 |
Agent for protein precipitation, a method of protein precipitation, a method of protein assay using protein precipitation agent, and a kit for protein assay
A method of protein precipitation, concentration and removal of non-protein agents from the protein solution wherein the protein solution is treated with a protein-precipitation agent containing an...
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6759384 |
Factor Xa inhibitors
The invention provides compounds which specifically inhibit factor Xa activity having the structure A 1 —A 2 —(A 3 ) m —B, where m is 0 or 1. A compound of the invention is characterized, in...
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6756354 |
Therapeutic compositions containing oligo (ethylene glycol)-terminated 1,2-dithiolanes and their conjugates
The present invention provides biotechnologically useful oligo(ethylene glycol)-terminated 1,2-dithiolane compositions and conjugates of these compositions with biological or non-biological...
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6737233 |
Method for preparing HCV E2 binding protein
A 24 kd percent capable of binding the E2 envelope protein of hepatitis C virus (HCV), and functionally equivalent variants or fragments of the 24 kd protein, are disclosed. Processes for...
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6676840 |
Fat and protein removal from process streams
The precipitation and removal of suspended fat and protein components and other suspended solids from a given solution can be accomplished by the addition of an aluminate to complex with the fat...
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6635746 |
Chlamydial vaccines and immunogenic compositions containing an outer membrane antigen and methods of preparation thereof
Immunogenic compositions including vaccines are described that comprise an outer membrane antigen extract of a strain of Chlamydia and are effective in protection against disease caused by...
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6610630 |
Chromatography adsorbents utilizing mercapto heterocyclic ligands
A pseudobioaffinity chromatography adsorbent adapted for use in selectively adsorbing immunoglobulins. In one embodiment, the adsorbent includes: (a) a solid support material; and (b) a ligand...
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6566329 |
Freeze-dried preparation of human growth hormone
A readily-soluble freeze-dried solid preparation of hGH with a minimal content of degradation products in terms of deamidation, dimers, polymers, and sulphoxide forms, obtainable by a method...
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6461604 |
Crystalline IL-6 and models of the molecular structure of IL-6
Crystallographic and NMR solution structures of human IL-6 are reported. The invention provides models and systems incorporating such structures which are useful for identifying IL-6/IL-6 receptor...
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6448374 |
Production of phosphopeptides from casein
A method for the preparation of selected phosphopeptides having anticariogenic and other activities, comprising the steps of completely digesting a soluble monovalent cation salt of casein in...
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6444211 |
Purification of a pertussis outer membrane protein
Pertactin (formerly 69 kDa protein) is recovered in stable biologically pure form having no detectable adenylate cyclase activity from fermentation broth from the fermentation of Bordetella...
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6437101 |
Methods for protein purification using aqueous two-phase extraction
Methods are provided in this invention for the isolation of human growth hormone, growth hormone antagonist, or a homologue of either, from a biological source. The methods of the invention use...
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6335430 |
Process of producing polyphenolic adhesive proteins and proteins produced in accordance with the process
The invention relates to a process of producing MAP-products from mussel feet. The process is characterised by extracting the mussel feet in a weakly acid aqueous solution containing, for instance,...
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6284874 |
Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
The present invention is directed to a process for purifying α 1 -proteinase inhibitor. The process comprises providing an impure protein fraction which comprises α 1 -proteinase inhibitor. The...
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6281336 |
Process for producing immunoglobulins for intravenous administration and other immunoglobulin products
The present invention relates to a process for purifying immunoglobulin G from a crude immunoglobulin-containing plasma protein fraction. Said process includes a number of steps of which the anion...
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6239261 |
Pasteurized, purified von Willebrand factor concentrate and a process for the preparation thereof
A process for the preparation of a concentrate of von Willebrand factor is described, entailing a solution of a complex of this factor with factor VIII:C being optionally pasteurized and treated...
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6166187 |
Method of concentrating prion proteins in blood samples
A sample is prepared from blood in a manner which makes it possible to further analyze proteins in the sample, e.g. to detect prions in the sample. Blood is extracted, allowed to clot and subjected...
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6160092 |
Crystal of the core portion of a signal transducer and activator of transcription (STAT)
The present invention provides a crystal of the core portion of the STAT protein in dimeric form with an 18-mer duplex DNA that contains a binding site for the STAT-dimer. The crystal is of...
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6140469 |
Protein isolate having an increased level of isoflavone compounds and process for producing the same
The present invention relates to the production of an isoflavone enriched vegetable protein isolate in which the weight ratio of material to extractant is controlled and washing of the acid...
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6080844 |
Process for the recovery and purification of a recombinant protein from a cell
The present invention involves a process of purifying and recovering a recombinant protein from a suspension of cells. The process of the present invention involves extracting a recombinant protein...
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6051694 |
Method for size reduction of proteins
Liquefied gases, compressed gases, and supercritical fluids are used to form protein particles without first dissolving the protein. The product material is expected to retain full activity and be...
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6051687 |
Purification of liquid protein hydrolysate and the resultant products
A method for removing excess salts, sulfites, sulfates and fatty components from liquid protein hydrolysate is described. Purified liquid protein products having reduced concentrations of salts,...
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6037457 |
Method for recombinant fibrinogen production
The present invention provides methods of producing recombinant fibrinogen in a long-term mammalian cell culture system. Disclosed is a method for the production of recombinant fibrinogen,...
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6020313 |
Method for inducing bone formation using an extract of human osteosarcoma cell line SAOS-2
The invention relates to a method for inducing bone formation via administration of an extract of devitalized, freeze dried Saos-2 cells. The extract is prepared by contacting the freeze dried...
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6013771 |
Isoflavone rich protein isolate and process for producing
A process for providing an isoflavone rich protein isolate is provided, along with the isoflavone rich protein isolate produced thereby. A vegetable material containing protein and at least one...
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5994508 |
Isoflavone rich protein isolate and process for producing
A process for providing an isoflavone rich protein isolate is provided, along with the isoflavone rich protein isolate produced thereby. A vegetable material containing protein and at least one...
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5990289 |
Method for the purification of proteins
The instant invention relate to a new method for the purification of proteins using copper chelate-affinity chromatography, wherein the impure or pre-purified protein is adsorbed on immobilized...
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5981715 |
Process for increasing the yield of a protein which has been subjected to viral inactivation
The present invention is directed to a process for purifying alpha-1-PI. The process comprises providing an impure protein fraction which comprises alpha-1-PI. The impure protein fraction is...
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5977324 |
Process for concentrating protein with disease-related conformation
A method of concentrating a disease-related conformation of a protein such as the PrP Sc in a sample is disclosed. The method comprises liquefying the sample and adding a complexing agent such as...
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5912327 |
Method of purifying chemokines from inclusion bodies
The present invention relates to processes for the purification of proteins. More specifically, methods for solubilizing and purifying proteins expressed in an insoluble form using low...
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5900376 |
Agent for protein precipitation, a method of protein precipitation, a method of protein assay using protein precipitation agent, and a kit for protein assay
A method of a protein assay wherein a protein solution is treated with an acidic component followed by the addition of a precipitate-forming component, which results in precipitation of protein....
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5898067 |
Crystallization of proteins
A method of providing zinc containing crystals of a protein derivative which has a lysine residue which carries a lipophilic substituent on the ε-amino group, said method comprising providing a...
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5891429 |
Recombinant human granulocyte-macrophage-colony stimulating factor (GM-CSF)
A method for preparing and isolating a transformation vector containing CSF/cDNA is described. The method comprises: preparing RNA from a cell that produces CSF; preparing polyadenylated...
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5880266 |
Protein product from blood and/or hemoglobin
The invention relates to new protein derivatives of blood, blood-protein containing raw materials and hemoglobin, and more particularly to processed globin products, and to processes for producing...
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5851792 |
Aglucone isoflavone enriched vegetable protein whey whey protein material aglucone isoflavone material high genistein content material and high daidzein content material and process for producing the same from a vegetable protein whey
An aglucone isoflavone enriched vegetable protein whey, whey protein material, high genistein material, high daidzein material, and aglucone isoflavone material are provided, as well as a process...
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5834427 |
Casein phosphopeptide, casein containing same and process for the preparation thereof
The present invention relates to a purified casein phosphopeptide(CPP) having a novel amino acid sequence and a purified casein including same wherein the 25th Arg from N-terminal in a conventional...
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5831022 |
Purification of recombinant human IL-1α
A process for the production of essentially homogeneous soluble, stable, endotoxin free human recombinant interleukin-1α of enhanced specific activity is described. The process involves breaking...
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5808008 |
Method of producing human pluripotent hematopoietic colony stimulating factor
Highly purified Pluripotent hematopoietic colony-stimulating factor (pluripotent CSF), a glycoprotein (MW 19,600) constitutively produced by human tumor cells has been highly purified from low...
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5808006 |
Refolding of polypeptides like recombinant insulin-like growth factor IGF-I
A composition is provided comprising about 0.1 to 15 mg/ml of a polypeptide in a buffer having a pH of about 7-12 comprising about 5-40% (v/v) of an alcoholic or polar aprotic solvent, about 0.2 to...
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5773588 |
Method for purifying somatotropin monomers
There is provided a method for purifying a refold somatotropin monomer from a mixture of somatotropin monomers and somatotropin oligomers in an aqueous solution having a urea concentration of...
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