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9029102 Process for the purification of recombinant albumin  
A process is provided for the preparation of a highly pure albumin solution the process comprising subjecting albumin (preferably expressed and secreted by transformed yeast) to a series of...
8933204 Process for the industrial-scale purification of gamma globulins from human plasma for industrial applications  
The invention relates to a novel, industrial-scale process for the purification of gamma-immunoglobulins (IgG) starting from plasma or fractions thereof. The method involves two chromatographic...
8933205 Process for preparing purified drug conjugates  
The invention provides a process for preparing a cell-binding agent chemically coupled to a drug. The process comprises covalently attaching a linker to a cell-binding agent, a purification step,...
8921064 Method for purifying urate oxidase tetramers and octamers  
A naturally occurring or recombinant protein, especially a mutein of porcine urate oxidase (uricase), that is essentially free of large aggregates can be rendered substantially non-immunogenic by...
8877903 Separation of insoluble target proteins  
The present invention relates to a method of isolating an insoluble target protein from a suspension of intact or disrupted host cells. The invention also relates to insoluble target proteins...
8852606 Capsular polysaccharide solubilisation and combination vaccines  
Precipitated bacterial capsular polysaccharides can be efficiently re-solubilized using alcohols as solvents. The invention provides a process for purifying a bacterial capsular polysaccharide,...
8841251 Method for making a homogenous vaccine composition comprising a conjugate of EGF and 64K for the treatment of tumors  
A vaccine composition for therapeutic use thereof on cancer patients includes a chemical conjugate of human recombining Epidermic Growth Factor (hrEGF) and a combining protein P64k for performing...
8822655 Pre-filtration adjustment of buffer solutes  
Herein is reported a tangential flow filtration method with a pre-filtration solute concentration adjustment in order to ensure a defined concentration of the components of the solution after...
8778879 Homogeneous vaccine composition comprising a conjugate of EGF and P64K for the treatment of tumors  
The present invention concerns the biotechnology sector and more specifically human healthcare. In particular, the present invention describes a vaccine composition for therapeutic use thereof on...
8772461 Two-stage ultrafiltration/diafiltration  
The present invention provides a method for concentrating a protein, in particular a method for concentrating a plasma product, in particular IgG, using glycine in a (two-stage...
8735544 Value added whole stillage by-products from an ethanol production process  
An improved process for obtaining value added by-products from an ethanol production whole stillage is disclosed wherein the whole stillage is mixed with additives to form a nutrition enriched...
8669353 Process for producing milk fractions rich in secretory immunoglobulins  
The present invention concerns a process for producing compositions that are rich in secretory IgA (S-IgA) by fractionating milk containing S-IgA. Such compositions may be used in particular for...
8658773 Ultrafiltration concentration of allotype selected antibodies for small-volume administration  
Disclosed are methods, compositions and uses of high concentration antibody or immunoglobulin formulations for subcutaneous, intramuscular, transdermal or other local (regional) administration, in...
8648178 Method for purifying bone morphogenetic protein  
The present invention relates to a method for purifying a protein belonging to the TGF-β, superfamily, preferably BMP, and more preferably BMP-2. According to the invention, the number of...
8633302 Variable tangential flow filtration  
The current invention reports a method for concentrating an immunoglobulin solution by tangential flow filtration wherein the transmembrane pressure and the cross-flow are variable.
8604175 Method for purifying FSH or a FSH mutant  
The invention relates to a method for purifying a glycoprotein, preferably FSH or a FSH mutant, comprising the steps of subjecting a liquid containing FSH or a FSH mutant to: (1) a dye affinity...
8598319 Process for separating proteins fibrinogen, factor XIII and biological glue from a solubilized plasma fraction and for preparing lyophilised concentrates of said proteins  
The invention is related to a process for separating proteins fibrinogen, Factor XIII and biological glue from a solubilized plasma fraction and for preparing freeze-dried concentrates of said...
8580933 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Variable tangential flow filtration
 
The current invention reports a method for concentrating an immunoglobulin solution by tangential flow filtration wherein the transmembrane pressure and the cross-flow are variable.
8546548 Method to produce a highly concentrated immunoglobulin preparation for subcutaneous use  
The present invention relates to a new and improved method for preparing a highly concentrated immunoglobulin composition from pooled plasma for subcutaneous injection. A composition comprising...
8536315 Production and purification of recombinant arylsulftase  
The present invention pertains to a process for production of recombinant arylsulfatase A in a cell culture system, the process comprising culturing a mammalian cell capable of producing rASA in...
8519108 Method for preparing antigen effective for preventing anthrax infection  
The method of the present invention comprising successive column chromatography processes for the purification of an anthrax protective antigen can achieve an improved purity of the anthrax...
8506797 Downstream bioprocessing device  
Large-scale downstream processing of secreted recombinant proteins is provided in a single device, wherein the contents of a plurality of bioreactors are combined simultaneous to their harvesting...
8481693 Virus like particle purification  
Methods for purifying human Calciviruses are disclosed, including Noroviruses and Sapoviruses.
8470969 Apo-2 ligand/trail formulations  
The present invention relates generally to Apo2L/TRAIL purification involving crystallization.
8378073 Process for attaching effector molecules to proteins  
The present invention provides a process for attaching one or more effector molecules to one or more cysteines in a protein comprising: a) activating one or more cysteines in the protein by...
8367810 Purified plasmodium and vaccine compositions  
Disclosed are substantially purified Plasmodium sporozoites and preparations of Plasmodium sporozoites substantially separated from attendant non-sporozoite material, where the preparations of...
8354505 Process for obtaining a concentrate of Von Willebrand factor or a complex of factor VII/Von Willebrand factor and use of the same  
A concentrate of Von Willebrand Factor (VWF) or a complex of Factor VIII/VWF is prepared by creating a solution of VWF or a complex of Factor VIII/VWF containing VWF at a concentration of up to 12...
8344108 Method and system for corn fractionation  
Methods and apparatus for processing corn into one or more corn products. Zein is extracted from corn or corn products or by-products with a solvent. The corn-solvent mixture is separated into...
8344107 Method and system for corn fractionation  
Methods and apparatus for processing corn into one or more corn products. Oil is extracted from corn or corn products or by-products with a solvent. The corn-solvent mixture is separated into...
8129507 Atopic dermatitis inducer  
An atopic dermatitis inducer binding to a human own IgE antibody and activating mast cells and basophiles, which includes a purified human secretion fraction, or an antigenic molecule or an...
8043866 Immunochromatography method  
A object of the present invention is to provide an immunochromatography method that makes it possible to rapidly detect an ultratrace amount of an analyte that has been impossible to analyze by...
7993877 Process for the purification of recombinant albumin  
A process is provided for the preparation of a highly pure recombinant albumin solution having a nickel ion content of less than 100 ng per gram of albumin. The process comprises subjecting a...
RE42315 Nanostructured separation and analysis devices for biological membranes  
The present invention provides a nanostructured device comprising a substrate including nanotroughs therein; and a lipid bilayer suspended on or supported in the substrate. A separation method is...
7932355 Virally-safe factor VIII with a low content of higher multimers  
La present invention pertains to a composition of plasma-derived virally-safe factor VIII, obtained after nanometric filtration, said composition comprising von Willebrand factor (vWF) at a rate...
7906024 Shear protectants in harvest microfiltration  
The addition of buffer to a harvest stream during diafiltration can cause increased turbidity and have other undesirable effects including limiting product recovery. Methods and compositions...
7872108 Processes for isolating proteon nucleation centers (PNCs) from a biological sample obtained from an animal  
Compositions and methods for the isolation and manipulation of misfolded, or partially misfolded, proteins present in blood and other biological materials are provided. In one aspect of the...
7754860 Method for purifying FSH  
The invention provides a method for purifying recombinant FSH.
7744890 Methods and compositions with reduced opalescence  
Methods for reducing the opalescent appearance of a protein preparation by modifying the ionic strength of the preparation, as well as compositions, e.g., pharmaceutical compositions, of...
7728116 Method of preparing an osteogenic protein fraction  
In a method of isolating osteogenic protein from bone, in which an osteogenic protein-containing fraction is extracted from bone and enriched by a sequence of enrichment steps selected from...
7674885 Process for concentration of macromolecules  
The invention provides methods for concentrating a macromolecule from a solution comprising the macromolecule and an organic polymer by first subjecting the solution to ultrafiltration to produce...
7667009 Method for purifying modified major mite allergen  
A method for purifying a modified major mite allergen obtained by the genetic recombination technique and a purified modified major mite allergen obtained by said method for purification are...
7662930 Polishing steps used in multi-step protein purification processes  
Various embodiments of the present invention are directed to multi-step systems and methods for target-molecule purification that employ column-chromatography-based and/or...
7569671 Method and system for corn fractionation  
Methods and apparatus for processing corn into one or more corn products. Oil is extracted from corn or corn products or by-products with a solvent. The corn-solvent mixture is separated into...
7553938 Method of providing a purified, virus safe antibody preparation  
A method of preparing a purified, virus inactivated and virus safe antibody preparation from a starting solution comprising antibodies and contaminants, the method comprising the steps of: (a)...
7524932 Lactalbumin production process  
A method for producing an oligomeric form of α-lactalbumin which is in the molten globule-like state is described. The method suitably comprises exposing a source of α-lactalbumin in which the...
7521417 Method and apparatus for preparing an acellular red blood cell substitute  
A process is disclosed for the preparation of an essentially tetramer-free, substantially stroma-free, polymerized, pyridoxylated hemoglobin. Also disclosed is an essentially tetramer-free,...
7476726 Method of producing and purifying endostatin protein  
The present invention provides a method for recombinant production, recovery and purification of endostatin protein. This method may be employed for large scale recovery and purification of...
7442308 Process for removing viruses in fibrinogen solutions and fibrinogen obtained by said process  
A process for removing viruses in fibrinogen solutions and fibrinogen obtained thereof wherein the process starts with an adjusted purified fibrinogen solution, the adjusted purified solution is...
7399840 Proteosome influenza vaccine  
Improved forms of vaccines which comprise proteosomes and protein antigens are described. Vaccines which contain influenza HA as the antigen are used for illustration as to demonstrate efficacy....
7393936 Method for the recombinant production and purification of protein kinases  
A method for the recombinant production and purification of a protein kinase selected from the group consisting of tyrosine protein kinases and serine/threonine kinases by expressing a nucleic...
Matches 1 - 50 out of 280 1 2 3 4 5 6 >