Matches 151 - 200 out of 249 < 1 2 3 4 5 >
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5625038 Monoclonal antibodies specific for Erysipelothrix rhusiopathiae  
Monoclonal antibodies specific for an immunogen of Erysipelothrix rhusiopathiae can protect from lethal effects of infection with E. rhusiopathiae. The antibodies also are useful for evaluating the...
5618916 Purified protein which functions as a mycobacterial receptor for fibronectin  
A method for the treatment of superficial urinary tract tumors in a mammal involves administering a diagnostically effective amount of a liposomal composition comprising a liposome, a...
5616321 Method of treating bacterial meningitis with anti-tumor necrosis factor antibody  
Bacterial meningitis infection in a mammal is treated by intravenous infusion of a therapeutically effective amount of a monoclonal antibody which binds to tumor necrosis factor alpha and an...
5612182 Mycobacteriophage specific for the mycobacterium tuberculosis complex  
Mycobacteriophage DS6A has been characterized and found to specifically infect all species of the TB complex, without any detectable infection of mycobacteria species other than those of the TB...
5585098 Oral administration of chicken yolk immunoglobulins to lower somatic cell count in the milk of lactating ruminants  
A method for lowering somatic cell count in the milk of a lactating ruminant is disclosed. IgY antibodies are first obtained from the egg of a hen which has been actively immunized against one or...
5554371 Recombinant vaccine against Lyme disease  
A highly-antigenic, recombinant polypeptide of a molecular weight of about 110-kD by SDS-PAGE is disclosed, which is derived by transforming E. coli with a 7.1 kB DNA fragment from EcoR1-digested...
5521085 Transformed cell lines producing human monoclonal antibodies specific for Pseudomonas aeruginosa serotypes  
The present invention relates to human monoclonal antibodies capable of plurally binding with O-antigens of Pseudomonas aeruginosa, relates to novel parent cell lines for producing human hybridomas...
5510264 Antibodies which bind meningitis related homologous antigenic sequences  
Monoclonal antibodies capable of binding to a Meningitis Related Homologous Antigenic Sequence (MRHAS) are provided. The MRHAS is found in meningitis-causing organisms and chemokines involved in...
5510241 Method of testing for the presence of Salmonella serotypes expressing Salmonella enteritidis fimbrial antigen (SEFA) and reagents therefore  
A method of testing for the presence of Salmonella serotypes S. enteritidis and S. dublin is provided. Novel monoclonal antibodies are used to detect the presence of an epitope specific for these...
5501854 Hybrid reagents capable of selectively releasing molecules into cells  
Hybrid reagents comprising a first portion having an affinity for a cellular target and a second portion having an affinity for a bioactive molecule are described, said hybrid reagents being...
5502168 Monoclonal antibodies to a continuous and cross-reactive epitope and an isolated protein of a sexual stage of P. falciparum  
Monoclonal antibodies which recognize a continuous epitope in the sexual stages of P. falciparum. The epitope so recognized has the following amino acid sequence: ##STR1## Malaria vaccines based on...
5487890 Mammalian primate erythrocyte bound heteropolymerized monoclonal antibodies and methods of use thereof  
Mammalian red blood cells are used to safely and rapidly neutralize and/or clear antigens or immunogens from the circulatory system by binding to the RBC a monoclonal antibody specific for a...
5474905 Antibodies specific for streptococcus pneumoniae hemin/hemoglobin-binding antigens  
The present invention relates to the isolation of newly discovered hemin/hemoglobin-binding proteins of Streptococcus pneumoniae with approximate molecular weights of 18, 43, 55, 66 and 76 kDa,...
5468484 Method of prevention of pseudomonas infection  
The invention described includes methods and compositions useful in preventing infection by Pseudomonas aeruginosa and related organisms. Diclosed is a peptide having the sequence corresponding to...
5459048 DNA encoding 85kd polypeptide useful in diagnosis of Mycoplasma infections in animals  
A class of polypeptides useful in an in vitro diagnosis of Mycoplasma infection in animals is disclosed. These polypeptides are also capable of inducing an immune response in swine which were...
5436321 Antibodies to the lipopolysaccharide bonding opsonin septin  
An antibody to septin, in which septin is an opsonin. Septin is isolated from human serum and is present at high levels in normal serum in distinction to the acute phase protein lipoprotein binding...
5436154 Monoclonal antibodies against human Tumor Necrosis Factor α  
A monoclonal antibody is provided which is able to neutralize both human TNF α and TNF β, or a binding fragment thereof. A stable hybridoma cell line and progeny thereof are also provided which...
5426046 Human monoclonal antibody to lipid A of gram negative bacteria  
A human monoclonal antibody, C5, specific for lipid A of the endotoxin core of Gram-negative bacteria and the hybridoma cell line which produces the antibody. The monoclonal antibody is produced by...
5403718 Methods and antibodies for the immune capture and detection of Borrelia burgdorferi  
The invention relates to novel antigens associated with Borrelia burgdorferi which are exported (or shed) in vivo and whose detection is a means of diagnosing Lyme disease. The antigens are...
5399485 Methods and compositions for diagnosing cat scratch disease and bacillary angiomatosis caused by Rochalimaea henselae  
The present invention relates to a method of diagnosing cat scratch disease and a method of diagnosing bacillary angiomatosis in a subject by detecting the presence of Rochalimaea henselae or an...
5367058 Modified antibodies with increased affinity  
The present invention relates to modified antibodies and fragments which display an increased affinity for antigen as compared to the affinity of unmodified antibody for antigen. The most preferred...
5352446 Method of treating dental caries with monoclonal antibodies against the antigen I and antigen I/II of streptococcus mutans  
A method of combatting dental caries in a mammal comprises topical application to a surface of a tooth in the mammals mouth of a monoclonal antibody raised against antigen I or antigen I/II of...
5322788 Monoclonal anti-body to cell surface protein of the bacterium Streptococcus pneumoniae  
This invention relates to a monoclonal antibody (MAb) directed against a surface protein of Streptococcus pneumoniae, a hybridoma cell line producing said antibody, and the use of such an antibody...
5314995 Therapeutic interleukin-2-antibody based fusion proteins  
The present invention relates to antibody-based fusion proteins wherein a portion of an immunoglobulin molecule is linked to a biologically active ligand. In particular embodiments of the...
5294537 Monoclonal antibody assay for Listeria monocytogenes  
Mouse monoclonal antibodies which will specifically recognize the pathogen Listeria monocytogenes were produced by fusion of spleen cells from an animal immunized with live L. monocytogenes to an...
5260057 Method and product for the treatment of gastric disease  
This invention describes a product obtained from the isolation and concentration of specific immunoglobulins (antibodies) derived from the mammary secretions of cows immunized with Helicobacter...
5252711 Monoclonal antibodies useful in deodorizing skin and antibody fragments thereof  
The present invention is concerned with a monoclonal antibody or antigen-binding fragment of a monoclonal antibody produced by a hybridoma formed by fusion of cells from mouse myeloma cells and...
5252480 Human monoclonal antibody and hybridoma producing the same  
A human monoclonal antibody, which has prophylactic and therapeutic effect to infections diseases caused by Pseudomonas aeruginosa, and the epitope of which is located in the outer core moiety of...
5248594 Immunodiagnostic reagent specific for legionella  
A set of three unique monoclonal antibodies have been produced which recognize Legionella with particular specificity, without substantial cross-reactivity with non-Legionella bacteria. These...
5246851 Monoclonal antibody specific for a 14kd protein obtained from N gonorroeae  
A monoclonal antibody, specific for N. gonorrhoeae, specifically binds to a protein which is obtained from N. gonorrhoeae, which has a molecular weight of about 14 kD as determined by SDS-PAGE and...
5233024 Anti-idiotypic monoclonal antibodies for mucoid Pseudomonas aeruginosa, their preparation and use  
An anti-idiotypic monoclonal antibody, which induces production of mucoid exopolysaccharide-specific antibodies which are opsonic for mucoid Pseudemonas aeruginosa. The anti-idiotypic monoclonal...
5231003 Monoclonal antibodies specific for Toxin B of Clostridium difficile  
Monoclonal antibodies specific for Toxin B of Clostridium difficile are provided. Further, methods for making and using the antibodies are given, particularly the use of the antibodies for the...
5225331 Immunoassay for detecting group B streptococcus  
Immunoadsorbent combinations for the detection and diagnosis of group B streptococcus polysaccharide antigen, comprising an insoluble carrier, a capture agent having an affinity for specifically...
5223604 Pseudomonas exoenzyme S peptide composition and method  
A peptide having a sequence corresponding to an antigenic site in the protein exoenzyme S which is antigenically similar to a C-terminal portion of the Pseusdomonas aeruginosa pilin protein is...
5217872 Method for detection of Borrelia burgdorferi antigens  
The invention relates to novel antigens associated with Borrelia burgdorferi which are exported (or shed) in vivo and whose detection is a means of diagnosing Lyme disease. The antigens are...
H001198 Pseudomonas aeruginosa type-specific human monoclonal antibodies, their preparation and use  
Serotype-specific human anti-Pseudomonas monoclonal antibodies which bind to determinants of the cell wall lipopolysaccharides of P. aeruginosa are prepared from hybrid cell lines. The antibodies...
5212062 Method and composition to direct Chlamydia psittaci or Chlamydia trachomatis infection  
The present invention relates to a method to detect a Chlamydia infection. More particularly, this invention relates to the discovery of a genus specific antigen in Chlamydia psittaci strain DD-34...
5202422 Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use  
The present invention contemplates glycopolypeptide multimers having a polypeptide that contain an immunoglobulin amino acid residue sequence and an oligosaccharide that comprises a core...
5196337 Human monoclonal antibody, and its production and use  
A human monoclonal antibody, which has prophylactic and therapeutic effect to infectious diseases caused by Pseudomonas aeruginosa of serotypes A and H classified under the Japanese Committee's...
5190860 Differential diagnostic assay for brucellosis  
An immunoassay procedure is provided which exhibits increased specificity over current procedures. The procedure allows the differentiation of animals infected with Brucella abortus from animals...
5179018 Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria  
Mammalian monoclonal anti-lipopolysaccharide (LPS) antibodies which react with gram-negative bacteria across different genera are disclosed. The anti-LPS antibodies are useful for the treatment or...
5168063 Monoclonal antibody to enterohemorrhagic Escherichia coli 0157:H7 and 026:H11  
A monoclonal antibody specific for enterohemorrhagic Escherichia coli 0157:H7 and 026:H11 is produced by immunizing BALB/c mice with a strain of E coli 0157:H7. The antibody reacts strongly by an...
5162223 Hybridomas and resulting monoclonal antibodies directed against antigens of Bordetella pertussis  
A panel of monoclonal antibody (Mab) producing hybridomas directed against various antigens of Bordetella pertussis are disclosed herein. The hybridomas and the antigens that the resulting...
5159064 Preparation of virus-free antibodies  
Antibodies, including monoclonal antibodies (Mabs), can be made substantially free of infectious viruses by storing them in a liquid state at conditions of pH, temperature and time sufficient to...
5158870 Diagnostic methods for mycoplasma genitalium infections  
Monoclonal antibodies binding Mycoplasma genitalium more strongly than Mycoplasma pneumoniae, Mycoplasma hominis, Mycoplasma orale, Mycoplasma salivarium and Acholeplasm laidlawii are described...
5157113 Removal of nucleic acids from monoclonal antibody preparations  
An essentially pure and stablized antibody preparation comprising IgM antibodies having a purity greater than about 98% by weight and a nucleic acid content of less than about 200 pg per mg IgM. In...
5114712 Common antigen (PSC-A) to Pseudomonas aeruginosa which acts as an agent for protecting Pseudomonas aeruginosa infection  
PSC-A is a new serological common antigen to Pseudomonas aeruginosa having very low toxicity, and highly effective for protecting infection by any of the serotypes of Pseudomonas aeruginosa. PSC-A...
5089262 E87Ag antigens of Pseudomonas aeruginosa and monoclonal antibodies against them and hybridomas thereof  
P. aeruginosa E87Ag antigen comprising polysaccharide fraction with molecular weight of about 27,000 which is contained in lipopolysaccharide of P. aeruginosa; anti-P. aeruginosa human or mouse...
5071759 Hybridoma cell lines and monoclonal antibodies to clostridum difficile toxins A and B  
Monoclonal antibodies produced by a family of murine hybrid cell lines are cross-reactive with both toxin A and toxin B of Clostridium difficile. The monoclonal antibodies are useful in an...
5069896 Malodor inhibiting skin deodorant composition comprising a monoclonal antibody and method of deodorizing  
The present invention is concerned with a monoclonal antibody or antigen-binding fragment of a monoclonal antibody produced by a hybridoma formed by fusion of cells from mouse myeloma cells and...
Matches 151 - 200 out of 249 < 1 2 3 4 5 >