|
Match
|
Document |
Document Title |
|
|
5468484 |
Method of prevention of pseudomonas infection
The invention described includes methods and compositions useful in preventing infection by Pseudomonas aeruginosa and related organisms. Diclosed is a peptide having the sequence corresponding to...
|
|
|
5447840 |
Receptor of the small rhinovirus receptor group
A substantially pure receptor with binding activity for rhinoviruses of the small receptor group is disclosed, which has the following characteristics: (a) a molecular weight of 120 kD on a...
|
|
|
5440020 |
Platelet function inhibiting monoclonal antibody fragment
There is provided a novel monoclonal antibody fragment which inhibits platelet function and may be useful in the treatment of thrombotic diseases. The fragment is produced by proteolytic digestion...
|
|
|
5439362 |
Sex-associated membrane proteins and methods for increasing the probability that offspring will be of a desired sex
A method of sorting living cells based on DNA content. Mammalian sperm subpopulations enriched in X- or Y-sperm. X- and Y-enriched sperm-plasma-membrane vesicles. Substantially pure sex-associated...
|
|
|
5428134 |
Antibody reagents that specifically bind to the carboxyl-terminal decaptide of specific GTP-binding proteins
Antibodies which bind to a peptide having the sequence KENLKDCGLF, which represents the C-terminal decapeptide of the GTP-binding protein transducin-α, are described. Binding to transducin-α by...
|
|
|
5425937 |
Hair treatment composition and hair care product, both containing anti-keratin antibody, and production of anti-keratin antibody
Hair treatment compositions, hair damage protective agents and hair care products, each contain an active ingredient comprising an antibody which binds to human hair keratins which constitute...
|
|
|
5426046 |
Human monoclonal antibody to lipid A of gram negative bacteria
A human monoclonal antibody, C5, specific for lipid A of the endotoxin core of Gram-negative bacteria and the hybridoma cell line which produces the antibody. The monoclonal antibody is produced by...
|
|
|
5413910 |
Measuring non-dystrophin proteins and diagnosing muscular dystrophy
The invention pertains to the dystrophin-glycoprotein complex of mammalian skeletal muscle and a method of isolating said complex. The components of the complex and methods of separating and...
|
|
|
5414072 |
Anti-octopus rhodopsin monoclonal antibody
The invention relates to a monoclonal antibody which binds to octopus rhodopsin and octopus metarhodopsin wherein said monoclonal antibody binds with higher affinity to metarhodopsin than to...
|
|
|
5389518 |
Monoclonal antibodies directed against vitronectin and fibronectin, and uses thereof
The present invention provides monoclonal antibodies directed against specific domains of fibronectin and vitronectin. These monoclonals may be used in the production of the biomaterial and devices...
|
|
|
5362643 |
Antibodies to epitopes present on membrane-bound but not secreted IGA
The invention relates to antibodies which immunologically bind epitopes present on B cell-bound but not secreted IgA. This is accomplished by targeting extracellular epitopes on the membrane...
|
|
|
5342756 |
Type III collagen degradation assay
The degradation of type III collagen in the body is quantitatively determined by measuring the concentration of the liberated aminoterminal telopeptide region of the type III collagen molecule in...
|
|
|
5336618 |
Fibrinogen blocking monoclonal antibody
There is provided a novel monoclonal antibody of the class IgG 1 which reacts readily with both normal human and dog blood platelets while failing to react with thrombasthenic human platelets....
|
|
|
5320942 |
Method of diagnosing the presence of abnormal epithelial tissue using monoclonal antibodies to the A.sub.6 B.sub.4 cell surface protein
The present invention discloses a novel cell surface marker and antigenic portions thereof; antibodies reactive with said marker; polynucleotides encoding said marker and antigenic portions...
|
|
|
5312751 |
Hybridoma producing a monoclonal antibody specific for an antigen of the stratum corneum of human epidermis
The subject invention relates to monoclonal antibodies which react with antigenic determinants which are present of the stratus corneum of human epidermis. Furthermore, the invention also relates...
|
|
|
5310551 |
Method for inhibiting pulmonary oxygen toxicity
A method for inhibiting pulmonary oxygen toxicity in a patient requiring elevated levels of inhaled oxygen, by prophylactic administration of certain adhesion molecules and antibodies thereto.
|
|
|
5310874 |
Integrin α subunit cytoplasmic domain polypeptides and antibodies
Diagnostic systems, methods, polypeptides and antibodies for detecting the presence of the cytoplasmic domain of the integrin α 6B or α 3B subunit in a body sample are disclosed
|
|
|
5310786 |
Reversibly precipitable, water-soluble polymer conjugates
The invention relates to polymer conjugates which are reversibly precipitable from aqueous solution and are composed of a carrier polymer which is soluble in aqueous medium and of a catalytically...
|
|
|
5298605 |
Antibodies to islet amyloid polypeptide (IAPP) and subunits thereof
This invention is directed to antibodies which react with human islet amyloid polypeptide and which do not significantly react with insulin or calcitonin gene-related peptides. Preparations of...
|
|
|
5292667 |
Detection and treatment of ulcerative colitis
A monoclonal antibody which binds preferentially to colonic glycoproteins of cells of persons having ulcerative colitis, compared to colonic glycoproteins of cells of persons not having ulcerative...
|
|
|
5286628 |
Monoclonal antibodies to mite allergen and the use thereof
The invention provides an anti Derf II monoclonal antibody selectively recognizing Derf II and belonging to an IgG or IgM class, the antibody being obtained by immunizing a mammal with Derf II...
|
|
|
5279822 |
Monoclonal antibodies against the 28KD protein of S. mansoni
A hybridoma is provided which provides a monoclonal antibody of isotope IgG2a, which recognizes a strip corresponding to a peptidic fragment of 8kD, isolated by controlled proteolysis of the 28kD...
|
|
|
5279958 |
Surface protein of basal epidermal cells, antibodies capable of recognizing said protein, and their use, and hybrid cellular stocks capable of secreting such antibodies
A protein characterized by the fact that it is a non-keratinic protein present on the apicolateral surface and absent on the basal surface of basal epidermal cells, in particular in man, that it is...
|
|
|
5273743 |
Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
The present invention has multiple aspects. In its first aspect the present invention is directed to a trifunctional antibody-like compound that has tissue, organ, cell or molecule specificity and...
|
|
|
5270165 |
Method of diagnosis of amyloidoses
A method of diagnosing a disease with cerebrovascular deposition of amyloid, including Alzheimer's disease, hereditary cerebral hemorrhage with amyloidosis-Dutch type and other amyloidoses, in a...
|
|
|
5264351 |
Monoclonal antibodies against autoimmune RNA proteins
Monoclonal antibodies against autoimmune RNA proteins such as La/SSB, Ro/SSA, nNP and Sm. These monoclonal antibodies, which are produced by a continuous hybridoma cell line, may be used in methods...
|
|
|
5262520 |
Peptides and antibodies that inhibit integrin-ligand binding
Polypeptides derived from the ligand-binding portion of an Integrin alpha subunit are disclosed as are their use for modulation of Integrin ligand binding. Anti-peptide antibodies, hybridomas...
|
|
|
5256561 |
Monoclonal antibody to HIV-2 and uses thereof
A monoclonal antibody which specifically binds to HIV-2 gp36 antigen and does not specifically bind to HIV-1 antigens. The monoclonal antibody is useful in immunoassays as a capture reagent, as...
|
|
|
5234815 |
Monoclonal antibodies against cytosolic thyroid hormone binding protein
Antibodies having specific binding affinity for substantially pure, isolated, thyroid hormone binding protein (p58) are described.
|
|
|
5232834 |
Anti-human sperm antibody, and its production and use
A monoclonal or polyclonal antibody having a specific binding property to an antigenic site on the human sperm acrosome, which is produced by a hybridoma obtained by fusion between an...
|
|
|
5227160 |
Monoclonal antibody NUH2 capable of inactivating motility of human sperm, antigen defined by said monoclonal antibody and methods of using said monoclonal antibody and antigen
Monoclonal antibody NUH2 produced by a hybridoma having ATCC deposit no. HB 9762. An isolated antigen capable of specifically binding to anti-human sperm antibodies including NUH2 and comprising at...
|
|
|
5204449 |
Antigen antibody conjugate for major histocompatibility complex (MHC) class I or II antigens
An antigen antibody conjugate is provided including at least one antigen and at least one monoclonal antibody having a specificity for at least one major histocompatibility complex (MHC) class I or...
|
|
|
5202252 |
Monoclonal antibodies against lens epithelial cells and methods for preventing proliferation of remnant lens epithelial cells after extracapsular extraction
Compositions and methods for their use are provided for preventing proliferation of remnant lens epithelial cells following extracapsular extraction. Complement-fixing monoclonal antibodies...
|
|
|
5196337 |
Human monoclonal antibody, and its production and use
A human monoclonal antibody, which has prophylactic and therapeutic effect to infectious diseases caused by Pseudomonas aeruginosa of serotypes A and H classified under the Japanese Committee's...
|
|
|
5185245 |
Immumoassays and kit for detection of proteoglycans
The invention discloses methods of detecting proteoglycans in synovial fluid and methods of monitoring treatment of diseases characterized by breakdown of proteoglycans into synovial fluid. A test...
|
|
|
5180808 |
Versican core protein, nucleic acid sequences encoding the same, nucleic acid probes, anti-versican antibodies, and methods of detecting the same
The invention relates to the fibroblast proteoglycan, versican. The versican core protein has the amino acid sequence, and is encoded by the nucleotide sequence, as shown in FIG. 1. The nucleotide...
|
|
|
5179019 |
Therapeutic murine monoclonal antibody
The present invention relates to a monoclonal antibody which is broadly reactive with all normal human peripheral blood mononuclear cells and granulocyte, and to the hybridoma cell line which...
|
|
|
5179197 |
Secretory component-containing composition
A secretory component-containing composition which is obtainable by contacting a milk or a whey with a cation exchange resin to allow the resin to absorb a secretory component contained in the milk...
|
|
|
5175113 |
Modified β.sub.2 -microglobulin
Substantially pure modified β 2 -microglobulin (mβ 2 m) of the formula I ##STR1## wherein R 1 is 24-amino acid residue, with the sequence...
|
|
|
5168063 |
Monoclonal antibody to enterohemorrhagic Escherichia coli 0157:H7 and 026:H11
A monoclonal antibody specific for enterohemorrhagic Escherichia coli 0157:H7 and 026:H11 is produced by immunizing BALB/c mice with a strain of E coli 0157:H7. The antibody reacts strongly by an...
|
|
|
5162504 |
Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients
Monoclonal antibodies to prostatic cells, are produced by a hybridoma formed by fusing mouse lymphocytes and mouse myeloma cells. The monoclonal antibodies show specificity for a non-soluble,...
|
|
|
5162223 |
Hybridomas and resulting monoclonal antibodies directed against antigens of Bordetella pertussis
A panel of monoclonal antibody (Mab) producing hybridomas directed against various antigens of Bordetella pertussis are disclosed herein. The hybridomas and the antigens that the resulting...
|
|
|
5158893 |
Methods and compositions for screening carcinomas
Methods for determining the prognosis of human carcinomas utilizing a marker specific for malignant cells of aggressive cancers. Cell lines have been produced that secrete monoclonal antibodies...
|
|
|
5149786 |
Dopamine releasing protein and antibody
Dopamine releasing protein (DARP) is a protein which stimulates release of dopamine from dopaminergic neurons, and is effective at extremely low concentrations. DARP is useful for stimulating...
|
|
|
5142028 |
Monoclonal antibodies capable of recognizing gangliosides GQ.sub.1b and GT.sub.1a
A monoclonal antibody specifically recognizes an epitope or an antigenic determinant represented by the following formula and specifically reacts therewith: ##STR1## The monoclonal antibody can be...
|
|
|
5141849 |
Marker for early detection of human hydatidiform moles and choriocarcinomas
The present invention relates to a DNA segment comprising linked pregnancy-specific beta 1 -glycoprotein (PSβG) genes encoding PSGGA protein and PSGGB protein. The invention further relates to a...
|
|
|
5124264 |
Monoclonal antibody recognizing atrial natriuretic polypeptide
A monoclonal antibody which recognizes the N-terminal of α-atrial natriuretic polypeptide (α-ANP). A hybridoma producing said monoclonal antibody and a process for immunoassay of α-ANP are also...
|
|
|
5114863 |
Immunosorbant assay for α-1-antitrypsin, kit employing said assay, monoclonal antibody to α-1-antitrypsin, and hybridoma for producing said monoclonal antibody
A double antibody sandwich immunosorbent assay for detecting alpha-1-antitrypsin (α 1 AT) comprising the steps of: (1) reacting (a) a first-species-of-animal antibody to α 1 AT with (b) a solid...
|
|
|
5102658 |
Antibody treatment for adiposity
A method of preventing controlling or reducing adiposity in which an animal or human being is treated with an effective amount of an antibody to an adipocyte present respectively in said animal or...
|
|
|
5059521 |
Monoclonal antibodies against prosumal proteins
The invention relates to monoclonal antibodies against prosomal proteins of a prosome, said prosome having a sedimentation coefficient of approximately 19S, and to a method for detecting cancer...
|